Abstract: The present invention relates to imidazo[4,5-c]quinoline compounds and to their use in the inhibition, regulation and/or modulation of signal transduction by ATM kinase and, in particular, for the treatment of ATM mediated diseases, especially cancer.

Abstract: The invention relates to a stimulation electrode for a stimulation device for stimulating organs in the case of spinal paraplegia, more particularly in the case of detrusor sphincter dyssynergia, including an electrode shaft, at one end of which an electrode tip is arranged for emitting a stimulation signal and at the other end of which a connection region is provided for a signal line, and also at least one fixing mechanism for fixing the position of the electrode shaft in the surrounding tissue along the longitudinal axis of said electrode shaft, fixing mechanism having at least one holding member preventing a withdrawal and at least one holding member preventing an advance.