Abstract: The present invention relates to compositions and methods for cell transplantation. In particular, the present invention provides a composition comprising procoagulant cells and at least one factor Xa inhibitor, preferably rivaroxaban, as well as at least one thrombin inhibitor, preferably bivalirudin.

Abstract: A method of treating liver-based inborn, metabolic deficiencies is disclosed by treatment of an individual, such as a patient suffering from liver-based inborn, metabolic deficiencies, with human progenitor or stem cells, a cell population or their progeny. The cells used in the treatment have the following characteristics. They are positive for vimentin, ?-smooth muscle actin (ASMA), and for at least one mesenchymal marker such as CD90, CD29, CD73, and CD44. They are positive for at least one hepatocyte marker such as albumin, alpha-fetoprotein, alpha-1 antitrypsin, HNF-4 and MRP2 transporter. They express at least one hepatocyte-like property or function such as G6P, CYP1B1, CYP3A4, TDO, TAT, GS, GGT, CK8, and EAAT2. They are negative for at least one marker such as cytokeratin-19, CD45, CD34, CD49f, CD133, HLA-DR, and CD117. They have mesenchymal-like morphology. They originate from human adult liver cells.

Abstract: A vortex chamber device comprising: a reactor comprising at least one chamber having a substantially circular cross-section; a device for feeding at least one fluid that is gaseous or liquid into the chamber; a device for removing said one or more fluids from the chamber; a device for feeding powder particles or a powder particles precursor to said chamber; wherein said fluid removing device comprises at least one discharge opening for removing said at least one fluid from the chamber. The invention also provides a method for treating powder particles or a powder particles precursor.

Abstract: In an image sensor, a photo detector circuit applies a photo current to a capacitive node during a photo detection time interval. A front-end circuit comprises an input transistor having a control node that is coupled to the capacitive node. A switchable biasing arrangement puts the input transistor in a disabled state during the photo detection time interval. The input transistor is put in an enabled state after the photo detection time interval. This then causes the front-end circuit to provide an output signal that is representative of a voltage on the capacitive node after the photo detection time interval.

Abstract: Biomaterial having a multi-dimensional structure and comprising demineralized bone matrix dispersed within differentiated mesenchymal stem cells (MSCs) tissue, wherein MSCs are adipose tissue-derived stem cells. Method for producing this biomaterial comprising incubating MSCS in osteoblastic and/or chondrongenic medium in presence of demineralized bone matrix. Use of this biomaterial for alleviating or treating a bone or cartilage defect, supporting or correcting a congenital or acquired abnormality, supporting a bon or articular bone replacement following surgery or trauma, and/or supporting a musculoskeletal implant.

Abstract: The present invention provides a method for the quantification of NO in a blood sample comprising the steps of collecting a blood sample, dividing said collected blood sample into three blood subsamples, chemically treating one blood subsample with an antioxidant to at least partly reduce free radicals of said blood subsample, performing EPR measurement of said blood subsamples, performing a first comparison of said chemically treated blood subsample EPR measurement with the EPR measurement of a non-chemically treated blood sub-sample thereby obtaining a first comparison result and performing a second comparison of this result with an EPR measurement of the remaining blood subsample in order to eliminate background signals.

Abstract: The present invention relates to methods for determining the concentration of a free beta-lactam antibiotic in a biological sample. In particular, the present invention relates to methods for measuring a free beta-lactam antibiotic in a biological sample, comprising the steps of: (a) providing at least one class C beta-lactamase, a functional fragment or variant thereof; (b) providing at least one biological sample; (c) contacting said at least one class C beta-lactamase with said at least one biological sample; and (d) determining the concentration of said free beta-lactam antibiotic in said at least one biological sample.

Abstract: The present invention relates to a two-degree-of-freedom planar rehabilitating, monitoring and/or evaluating device comprising a first guiding mechanism (2), a second guiding mechanism (3), substantially parallel to the first guiding mechanism (2), a third guiding mechanism (4), substantially perpendicular to the first and second guiding mechanisms (2, 3), and an end-effector (5), wherein the third guiding mechanism (4) is connected to the first and second guiding mechanisms (2, 3), and wherein the end-effector (5) is connected to the third guiding mechanism (4). The present invention also relates to a two-degree-of-freedom planar rehabilitating, monitoring and/or evaluating interactive device adapted for rehabilitation, monitoring and/or assessment of the upper limbs of a subject, comprising said device.

Abstract: Transmission (10) comprising a sun (1), a planet carrier (4), a first planet (21) having a first axis of revolution (41) and a first lateral surface (31) that is nonparallel to it, and a ring (3). When there is a relative movement between said first planet (21) and said ring (3) for a constant transmission ratio, a force of power transmission, Formula (I), between said first planet (21) and said ring (3) defines a plane (55). The transmission (10) comprises rolling means (15) for allowing a movement of translation between said ring (3) and said first planet (21) along a direction of translation (65) that is perpendicular to said plane (55) such that different transmission ratios can be obtained, corresponding to different coupling points (8) between said first lateral surface (31) and said ring (3) along said direction of translation (65).

Abstract: The invention relates to a method for converting a polycondensed elastomeric thermoplastic polymer, including a step of extruding the polycondensed elastomeric thermoplastic polymer in the presence of water. The polycondensed elastomeric thermoplastic polymer is in particular chosen from copolymer block amides, copolyethers or copolyester block urethanes, copolyether block esters and the mixtures thereof, and is preferably a copolyether block amide.

Abstract: The invention provides a radial bearing for supporting a shaft of a rotating device comprising an inductor having an inductor axis, generating a magnetic field radial to said inductor axis having p pole pairs, a winding having loops disposed around a winding axis, magnetically coupled to said radial magnetic field, and connected in a closed circuit in such a manner that the net flux variation intercepted by said winding when said inductor and said winding are in rotation with respect to each other is zero when said inductor axis and said winding axis coincide, and a gap between said inductor and said winding. According to the invention, said armature winding comprises p?1 or p+1 pole pairs when p is larger than or equal to 1 and said armature winding comprises one pole pair when p is equal to 0.

Abstract: Novel phenazine derivatives of formula (I) are disclosed. In particular, substituted 2,3-dihydro-1H-benzo[a]pyrano[2,3-c]phenazines are disclosed. The compounds can be used as anti-angiogenic and/or anti-tumor agents.

Abstract: Isolated liver progenitor stem cells and cell populations of isolated liver progenitor stem cells are disclosed. The progenitor stem cells originate from adult liver, especially human adult liver. The isolated progenitor stem cells have uses in medicine, hepatology, inborn errors of liver metabolism transplantation, infectious diseases and liver failure. Methods of isolating these cells and their culture is described. The isolated cells are characterized before and after differentiation. Their use for transplantation and as animal models of human disease, toxicology and pharmacology is disclosed.

Abstract: According to a first aspect, the invention relates to a thermoelectric module (10) that comprises a thermoelectric layer (15) comprising one p-type (7p) and one n-type (7n) portions presenting together an upper and a lower main surfaces (11,12). The thermoelectric module (10) further comprises a first and a second thermal resistor elements (1r, 2r), and a first thermal bridge element (3c), between and adjacent to the first and second thermal resistor elements (1r, 2r). The first and second thermal resistor elements (1r, 2r) and the first thermal bridge element (3c) cover the whole lower main surface (12). The p-type (7p) and the n-type (7n) portions are adjacent and directly coupled by an interface (7i). The first thermal bridge element (3c) spans at least over the orthogonal projection of the interface (7i) on the lower main surface (12).

Abstract: The method of the invention relates to a method for welding a first (20) and a second (30) layers together. The second melting temperature of the second layer (30), Tm,2, is lower than the first melting temperature of the first layer (20), Tm,1. After having formed a layup (50) by placing the first layer (20) on top of the second layer (30), a rotating tool (70) is pressed and translated over at least a friction portion (15) of the upper surface (20u) of the first layer (20) such that the temperature reached by at least a portion of the upper surface (30u) of the second layer (30) is higher than the second melting temperature, Tm,2. Restraining means allow preventing molten second material from flowing out of the layup (50). Materials of first (20) and second (30) layers are chosen among the following materials: metals, semi-metals, or semiconductors.

Abstract: The invention relates to a method for converting a polycondensed elastomeric thermoplastic polymer, including a step of extruding the polycondensed elastomeric thermoplastic polymer in the presence of water. The polycondensed elastomeric thermoplastic polymer is in particular chosen from copolymer block amides, copolyethers or copolyester block urethanes, copolyether block esters and the mixtures thereof, and is preferably a copolyether block amide.

Abstract: The present invention relates to compositions and methods for cell transplantation. In particular, the present invention provides a composition comprising procoagulant cells and at least one factor Xa inhibitor, preferably rivaroxaban, as well as at least one thrombin inhibitor, preferably bivalirudin.

Abstract: The present invention provides a method for the quantification of NO in a blood sample comprising the steps of collecting a blood sample, dividing said collected blood sample into three blood subsamples, chemically treating one blood subsample with an antioxidant to at least partly reduce free radicals of said blood subsample, performing EPR measurement of said blood subsamples, performing a first comparison of said chemically treated blood subsample EPR measurement with the EPR measurement of a non-chemically treated blood sub-sample thereby obtaining a first comparison result and performing a second comparison of this result with an EPR measurement of the remaining blood subsample in order to eliminate background signals.

Abstract: A system for measuring a solution pH includes a potentiostat with a working electrode made of an electro-conductive solid polymer transducer, an input to receive the potential to be applied between the working electrode and a reference electrode, and an output to transmit a signal representative of the current flowing between a counter electrode and the working electrode, the three electrodes being immerged into the solution. The system further includes a digital processor connected to a digital to analog converter for generating the potential to be applied between the working and the reference electrodes; and to an analog to digital converter for receiving a digital value representative of the current. The digital processor is adapted to modify the potential to maintain the current inside a predetermined range such that the potential is representative of the solution pH when the current is inside the predetermined range.

Abstract: An autonomous computer based method and system is described for personalized production of videos such as team sport videos such as basketball videos from multi-sensored data under limited display resolution. Embodiments of the present invention relate to the selection of a view to display from among the multiple video streams captured by the camera network. Technical solutions are provided to provide perceptual comfort as well as an efficient integration of contextual information, which is implemented, for example, by smoothing generated viewpoint/camera sequences to alleviate flickering visual artifacts and discontinuous story-telling artifacts. A design and implementation of the viewpoint selection process is disclosed that has been verified by experiments, which shows that the method and system of the present invention efficiently distribute the processing load across cameras, and effectively selects viewpoints that cover the team action at hand while avoiding major perceptual artifacts.