Patents Assigned to Universite de Caen Basse Normandie
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Patent number: 11474099Abstract: The invention relates to a novel method for diagnosing the sulfur nutrition state of a plant by measuring the content of certain mineral nutrients in the leaves.Type: GrantFiled: February 3, 2017Date of Patent: October 18, 2022Assignees: AGRO INNOVATION INTERNATIONAL, UNIVERSITE DE CAEN BASSE NORMANDIEInventors: Elise Sorin, Mustapha Arkoun, Florence Cruz, Jean-Claude Yvin, Anne Maillard, Sylvain Diquelou, Philippe Etienne, Alain Ourry
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Polypeptides derived from and their use for vaccination and the generation of therapeutic antibodies
Patent number: 11278609Abstract: Medicament for the treatment or the prevention of a bacterial infection, characterized in that it contains at least one polypeptide selected from the group of SEQ ID NO: 1 to SEQ ID NO: 9, and contiguous fragments thereof, wherein said at least one polypeptide or contiguous fragment thereof induces opsonic antibodies in a patient in need thereof. The polypeptides or the contiguous fragments thereof according to the present invention can be used for the preparation of a vaccine against an infection against Enterococcus.Type: GrantFiled: February 25, 2015Date of Patent: March 22, 2022Assignees: KLINIKUM DER UNIVERSITÄT MÜNCHEN, UNIVERSITE DE CAEN BASSE-NORMANDIEInventors: Johannes Hübner, Axel Hartke, Luis Felipe Romero Saavedra -
Publication number: 20190339259Abstract: The invention relates to a novel method for diagnosing the sulfur nutrition state of a plant by measuring the content of certain mineral nutrients in the leaves.Type: ApplicationFiled: February 3, 2017Publication date: November 7, 2019Applicants: Agro Innovation International, Universite de Caen Basse NormandieInventors: Elise SORIN, Mustapha ARKOUN, Florence CRUZ, Jean-Claude YVIN, Anne MAILLARD, Sylvain DIQUELOU, Philippe ETIENNE, Alain OURRY
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Patent number: 10307410Abstract: The invention relates to compounds of formula (I), and to their therapeutic use in the treatment of cancer: Wherein Y1, Y2, Ar1, Ar2, R1, R2, i, j, k, l are as defined in claim 1.Type: GrantFiled: March 3, 2015Date of Patent: June 4, 2019Assignees: CENTRE REGIONAL DE LUTTE CONTRE LE CANCER FRANCOIS BACLESSE, UNIVERSITE DE CAEN BASSE-NORMANDIE, INSTITUT DE CANCEROLOGIE DE L'OUEST RENE GAUDUCHEAUInventors: Laurent Poulain, Anne-Sophie Voisin-Chiret, Jana Sopkova-de Oliveira Santos, Ronan Bureau, Grégory Burzicki, Marcella De Giorgi, Serge Perato, Jade Fogha, Sylvain Rault, Philippe Juin, Fabien Gautier
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Patent number: 10239953Abstract: Disclosed herein is a bispecific inhibitor for use in treating thrombotic disorders, such as acute thrombotic disorders like stroke and thromboembolism. The bispecific inhibitor is based on monoclonal antibodies targeting TAFI and PAI-1, and shows efficacy in the presence or the absence of plasminogen activators such as tissue-type plasminogen activator (tPA).Type: GrantFiled: February 9, 2015Date of Patent: March 26, 2019Assignees: KATHOLIEKE UNIVERSITEIT LEUVEN, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE CAEN BASSE NORMANDIE, CENTRE HOSPITALIER UNVIERSITAIRE DE CAENInventors: Paul Declerck, Simon De Meyer, Nick Geukens, Ann Gils, Marina Rubio, Denis Vivien, Tine Wyseure
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Patent number: 10180427Abstract: Novel grafted dinuclear metal complexes having formula (I) or of formula (II) wherein M represents a metal ion, and also the use thereof as sensors in a method for detecting and/or characterising cellular microparticles.Type: GrantFiled: September 2, 2016Date of Patent: January 15, 2019Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE CAEN BASSE-NORMANDIE, UNIVERSITE GRENOBLE ALPESInventors: Catherine Belle, Gisele Gellon, Laurent Plawinski, Loic Doeuvre, Eduardo Angles Cano
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Patent number: 9845382Abstract: This invention relates to a method for producing functionalized telechelic oligomers, comprising two steps. The first step relates to bringing a raw material comprising at least one high-molecular-weight polymer comprising at least two unsaturations, into contact with a solution comprising at least one metathesis catalyst and at least one functionalizing agent. The second step relates to the separation of the functionalized telechelic oligomers produced by the metathesis reaction in ionic liquid medium of the first step.Type: GrantFiled: December 3, 2014Date of Patent: December 19, 2017Assignees: Centre National de la Recherche Scientifique, Universite de Caen Basse-Normandie, Universite du MaineInventors: Jean-Francois Pilard, Arnaud Nourry, Isabelle Dez, Annie-Claude Gaumont, Ali Mouawia
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Patent number: 9732334Abstract: The present invention relates to mutated tissue plasminogen activators, and their use for treating thrombotic diseases.Type: GrantFiled: December 17, 2015Date of Patent: August 15, 2017Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite de Caen Basse NormandieInventors: Denis Vivien, Jerome Parcq
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Publication number: 20170071921Abstract: The invention relates to compounds of formula (I), and to their therapeutic use in the treatment of cancer: Wherein Y1, Y2, Ar1, Ar2, R1, R2, i, j, k, l are as defined in claim 1.Type: ApplicationFiled: March 3, 2015Publication date: March 16, 2017Applicants: CENTRE REGIONAL DE LUTTE CONTRE LE CANCER FRANCOIS BACLESSE, UNIVERSITE DE CAEN BASSE-NORMANDIE, INSTITUT DE CANCEROLOGIE DE L'OUEST RENE GAUDUCHEAUInventors: Laurent POULAIN, Anne-Sophie VOISIN-CHIRET, Jana SOPKOVA-DE OLIVEIRA SANTOS, Ronan BUREAU, Grégory BURZICKI, Marcella DE GIORGI, Serge PERATO, Jade FOGHA, Sylvain RAULT, Philippe JUIN, Fabien GAUTIER
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Patent number: 9453837Abstract: Novel grafted dinuclear metal complexes having formula (I) or of formula (II) wherein M represents a metal ion, and also the use thereof as sensors in a method for detecting and/or characterising cellular microparticles.Type: GrantFiled: March 23, 2012Date of Patent: September 27, 2016Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE CAEN BASSE-NORMANDIE, UNIVERSITE JOSEPH FOURIERInventors: Catherine Belle, Gisele Gellon, Laurent Plawinski, Loic Doeuvre, Eduardo Angles Cano
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Publication number: 20160194623Abstract: The present invention relates to mutated tissue plasminogen activators, and their use for treating thrombotic diseases.Type: ApplicationFiled: December 17, 2015Publication date: July 7, 2016Applicants: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite de Caen Basse NormandieInventors: Denis VIVIEN, Jerome PARCQ
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Patent number: 9249406Abstract: The present invention relates to mutated tissue plasminogen activators, and their use for treating thrombotic diseases.Type: GrantFiled: September 7, 2012Date of Patent: February 2, 2016Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite de Caen Basse NormandieInventors: Denis Vivien, Jerome Parcq
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Patent number: 8926736Abstract: The present invention relates to reducible porous crystalline solids, constituted of a metal-organic framework (MOF), for the separation of mixtures of molecules having different unsaturation degrees and/or a different number of unsaturations with a selectivity that can be adjusted by controlling the reduction of the MOF. The MOF solids of the present invention, after reduction, have a strong affinity for molecules containing at least one unsaturation. They can be used in various separation processes, especially those relating to hydrocarbons.Type: GrantFiled: June 11, 2009Date of Patent: January 6, 2015Assignees: Centre National de la Recherche Scientifique -CNRS-, Universite de Caen-Basse Normandie, Universite de Versailles—Saint Quentin en Yvelines, Korea Research Institute of Chemical & Technology (KRICT)Inventors: Christian Serre, Alexandre Vimont, Philip Llewellyn, Jong-San Chang, Patricia Horcajada-Cortes, Gérard Ferey, Marco Daturi, Young-Kyu Hwang
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Patent number: 8541189Abstract: The invention relates to a method for measuring the plasmine activity of microparticles, in particular circulating microparticles, in a sample of a biological fluid, particularly a biological fluid in a flow situation, wherein said method can be used as a diagnosis method or a method for following a treatment.Type: GrantFiled: June 6, 2008Date of Patent: September 24, 2013Assignees: Institut National de la Sante et de la Recherche Medicale (Inserm), Assistance Publique—Hopitaux de Marseille, Universite d'Aix-Marseille, Universite de caen Basse-NormandieInventors: Eduardo Angles Cano, Romaric Lacroix, Florence Malaterre, Françoise Dignat-George
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Patent number: 8126140Abstract: A method of generating a pseudorandom data sequence, wherein said pseudorandom data sequence is generated by a procedure for searching for a search pattern in an initial data sequence of N bits, said search procedure comprising the following steps: (a) detecting in said initial data sequence a particular search pattern of r bits that is one of a set of search patterns; (b) determining an output pattern of k bits by an operation that depends on the progress of the preceding step; and repeating the preceding steps (a) and (b) successively to form the pseudorandom data sequence from a succession of output patterns.Type: GrantFiled: August 2, 2004Date of Patent: February 28, 2012Assignees: France Telecom, Universite de Caen Basse NormandieInventors: Herve Sibert, Aline Gouget
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Publication number: 20110172412Abstract: The present invention relates to reducible porous crystalline solids, constituted of a metal-organic framework (MOF), for the separation of mixtures of molecules having different unsaturation degrees and/or a different number of unsaturations with a selectivity that can be adjusted by controlling the reduction of the MOF. The MOF solids of the present invention, after reduction, have a strong affinity for molecules containing at least one unsaturation. They can be used in various separation processes, especially those relating to hydrocarbons.Type: ApplicationFiled: June 11, 2009Publication date: July 14, 2011Applicants: Universite De Caen-Basse Normandie, Centre National De La Recherche Scientifique- CNRS-Inventors: Christian Serre, Alexandre Vimont, Philip Llewellyn, Jong-San Chang, Patricia Horcajada-Cortes, Gérard Ferey, Marco Daturi, Young-Kyu Hwang