Abstract: The present invention concerns a TCTP antagonist, in particular a nucleic acid targeting an m RNA encoding Translationally-Controlled Tumor Protein (TCTP), wherein said nucleic acid is capable of reducing the amount of TCTP in cells, for use in the treatment or prevention of hormone-independent cancer or chemo-resistant cancer, such as an androgen-independent prostate cancer.
Type:
Application
Filed:
April 16, 2015
Publication date:
August 6, 2015
Applicants:
Institut National De La Sante Et De La Recherche Medicale (Inserm), UNIVERSITE DE LA MEDITARRANEE AIX-MARSEILLE II
Abstract: The present invention concerns a TCTP antagonist, in particular a nucleic acid targeting an m RNA encoding Translationally-Controlled Tumor Protein (TCTP), wherein said nucleic acid is capable of reducing the amount of TCTP in cells, for use in the treatment or prevention of hormone-independent cancer or chemo-resistant cancer, such as an androgen-independent prostate cancer.
Type:
Application
Filed:
December 19, 2011
Publication date:
October 10, 2013
Applicant:
UNIVERSITE DE LA MEDITARRANEE AIX-MARSEILLE II