Patents Assigned to Universite de la Mediterranee Aix-Marseilles 2
  • Use of poly-?2,8-sialic acid mimetic peptides to modulate NCAM functions
    Patent number: 8048858
    Abstract: A peptide consisting of 5 to 30 amino acid residues, preferably 9 to 15, most preferably about 12 amino acid residues, comprising a B epitope of a poly-?2,8 sialic acid attached to NCAM which is recognized by an anti-poly-?2,8 sialic acid (PSA) antibody, the use thereof and the preparation of a medicament for modulating NCAM functions, to be administered for the prevention and/or the treatment of neurodegenerative diseases, brain and spine lesions, age-related learning and memory problems, and cancer is disclosed.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: November 1, 2011
    Assignees: Centre National de la Recherche Scientifique, Universite de la Mediterranee Aix-Marseilles 2, Schafer-N, Universitaetsklinikum Hamburg-Eppendorf
    Inventors: Genevieve Rougon, Pascal Torregrossa, Melitta Schachner, Claus Schafer Nielsen