Patents Assigned to Universite de Limoges
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Publication number: 20190221992Abstract: A method and system for adjusting the profile of a laser wavefront formed by at least a laser beam to a desired laser wavefront profile, the laser beam or beams presenting random phases and intensities, comprises a mixing module, configured to generate, from interference phenomena among the laser beam or beams, a laser field, a second intensity measuring module configured to measure the mixed intensities of the laser field portions, a calculation unit configured to calculate one or several phase correction values of the phase of the laser beam or the phases of laser beams, from the intensities of the laser beams, the mixed intensities and one or several predetermined target phases, and a phase adjustment module configured to apply the phase correction value or values obtained from the calculation unit to the laser beam phases.Type: ApplicationFiled: January 17, 2019Publication date: July 18, 2019Applicants: COMPAGNIE INDUSTRIELLE DES LASERS CILAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DE LIMOGESInventors: Paul Armand, Jérémy Saucourt, Vincent Kermene, Agnès Desfarges-Berthelemot, Joël Benoist, Alain Barthelemy, Julien Leval
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Patent number: 10243316Abstract: The invention relates to a method for triggering a pulsed light source, wherein it comprises at least one iteration of the following steps: receiving a control signal; determining what is called a separation time between the reception of said control signal and at least one preceding control signal; adjusting at least one control parameter of said pulsed light source depending at least on said separation; generating at least one electrical signal for triggering the pulsed light source depending on said at least one control parameter adjusted during the preceding step; and triggering the pulsed light source depending on said at least one triggering electrical signal.Type: GrantFiled: March 30, 2016Date of Patent: March 26, 2019Assignees: HORIBA ABX SAS, UNIVERSITE DE LIMOGES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Vincent Couderc, Roland Grando, Alexis Labruyere, Nelly Rongeat, Denisa Subtirelu
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Publication number: 20190056373Abstract: A method for determination of the behavior of a reactive mixture intended for obtaining a geopolymer. The reactive mixture comprises at least one aluminosilicate material. The method includes determining a proportion of amorphous phase of the at least one aluminosilicate material and determining a degree of wettability of the at least one aluminosilicate material. If the proportion of amorphous phase is greater than 45% and if the degree of wettability is situated in a range between 300 ?g/l and 1400 ?g/l, then the reactive mixture, formed by the reaction of the at least one aluminosilicate material with an alkaline solution, forms a geopolymer.Type: ApplicationFiled: October 27, 2016Publication date: February 21, 2019Applicants: UNIVERSITE DE LIMOGES, CNRSInventors: Ameni Gharzouni, Laëticia Vidal, Sylvie Rossignol, Elodie Prud'Homme, Alexandre Autef, Emmanuel JOUSSEIN
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Patent number: 10199177Abstract: The invention relates to a method for the synthesis of a nanocomposite compound comprising TiO2 nanoparticles bound to carbon nanostructures, characterized in that it comprises the following steps: a) mixing carbon nanostructures and at least one TiO2 precursor in a first liquid in order to form a stock suspension; b) nebulizing said stock suspension and transporting it into a reaction chamber by means of a gaseous flow; and c) carrying out laser pyrolysis of said stock suspension in said reaction chamber in order to simultaneously form TiO2 nanoparticles and graft them onto the nano structures.Type: GrantFiled: July 13, 2015Date of Patent: February 5, 2019Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LIMOGESInventors: Nathalie Herlin, Jin Wang, Mathieu Pinault, Johann Boucle
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Publication number: 20190027890Abstract: Some embodiments relate to a generation device that includes: a pulsed laser source generating primary photons having at least one wavelength within pulses having time dissymmetry, a forming device(s) controlling the primary photons so as to generate a selective-polarization, focused input beam, and an optical fiber wherein the primary photons induce secondary photons having different wavelengths resulting from a raman conversion cascade and forming a wide-spectrum output beam having substantially constant energy.Type: ApplicationFiled: January 20, 2017Publication date: January 24, 2019Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LIMOGESInventors: Christophe LOUOT, Dominique PAGNOUX, Katarzyna KRUPA, Badr SHALABY, Alexis LABRUYÈRE, Alessandro TONELLO, Vincent COUDERC
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Publication number: 20180344760Abstract: The present invention concerns a treatment of diseases involving B cells, B lymphocytes or plasmocytes. In particular, it concerns an antisense oligonucleotide or a mixture of antisense oligonucleotides capable of inducing exon skipping at the RNA of the immunoglobulin heavy or light chains, for the use of same in the treatment of diseases involving B cells.Type: ApplicationFiled: November 22, 2016Publication date: December 6, 2018Applicants: Universite de Limoges, Centre National de la Recherche ScientifiqueInventors: Laurent Delpy, Nivine Srour, Michel Cogné
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Patent number: 10116114Abstract: According to the invention, a plurality of elementary laser beams (fi) are generated, the phases of which are adjusted by an electro-optical feedback loop (6, 7i, 8i, 9) implementing the matrix equation of a phase-contrast filtering device (6).Type: GrantFiled: October 14, 2015Date of Patent: October 30, 2018Assignees: COMPAGNIE INDUSTRIELLE DES LASERS CILAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE LIMOGESInventors: Vincent Kermene, Agnes Desfarges-Berthelemot, Paul Armand, Joel Benoist, David Kabeya, Alain Barthelemy, David Sabourdy, Jean-Eucher Montagne
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Patent number: 10053780Abstract: Process for depositing a corrosion-protection coating on at least one portion of the surfaces of a metallic substrate having at least one cavity with an equivalent diameter emm<2 mm and a length/width ratio of greater than 150, using an aqueous suspension comprising powder of the metal to be deposited on the substrate combined with an agent for protecting the surface of the metal powder, a diluent, and at least one additive, the particles of the suspension each having an equivalent diameter d such that d?emm/10.Type: GrantFiled: September 17, 2014Date of Patent: August 21, 2018Assignees: L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude, Centre National de la Recherche Scientifique, Université de Lorraine, Université de LimogesInventors: Thierry Chartier, Pascal Del-Gallo, Sebastien Doublet, Thierry Mazet, Laurent Prost, Nicolas Ramenatte, Fabrice Rossignol, Michel Vilasi
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Patent number: 10038441Abstract: A power switching cell with normally on field-effect transistors comprises a current switch receiving the control input signal over an activation input and a power transistor for switching a high voltage VDD applied to its drain, to its source that is connected to the output port of the cell. The control of the gate of the power transistor whose source is floating, according to the input signal, is provided by a self-biasing circuit connected between its gate and source. The current switch is connected between the self-biasing circuit and a zero or negative reference voltage. The self-biasing circuit comprises a transistor whose source or drain is connected to the gate or source of the power transistor. The gate of this transistor is biased by a resistor connected between its gate and source, and between the current switch and the source. The transistors are HEMT transistors using GaN or AsGa technology.Type: GrantFiled: April 17, 2015Date of Patent: July 31, 2018Assignees: THALES, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE DE LIMOGES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Olivier Jardel, Raymond Quere, Stéphane Piotrowicz, Philippe Bouysse, Sylvain Delage, Audrey Martin
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Patent number: 9872483Abstract: The invention relates to a transgenic non-human mammal comprising human immunoglobulin mu and epsilon heavy-chain constant transgenes C? and C? inserted in place of endogenous mu heavy-chain switch sequence S?, and its use for producing chimeric human immunoglobulin E antibodies specific for an antigen of interest.Type: GrantFiled: July 3, 2014Date of Patent: January 23, 2018Assignees: B CELL DESIGN, UNIVERSITE DE LIMOGESInventors: Michel Cogne, Brice Laffleur, Armelle Cuvillier, Marie Bosselut
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Patent number: 9810837Abstract: A waveguide with a hollow core (16) delimited by a closed contour includes a succession of arcs (20) of negative curvature, each arc including a chord (24), characterized in that the contour of the hollow core (16) includes small arcs (PA) and large arcs (GA) arranged alternately, each arc (20) being symmetric with respect to a straight line passing through the center (18) of the hollow core (16) and the middle of the chord (24) thereof, the ratio b=2Ra/C of the large arcs being greater than 0.9 for the large arcs (GA), Ra corresponding to the maximum distance between the chord (24) and the arc (20), C corresponding to the length of the chord (24).Type: GrantFiled: June 4, 2014Date of Patent: November 7, 2017Assignees: UNIVERSITE DE LIMOGES, CNRS, GLOPHOTONICSInventors: Fetah Benabid, Frederic Gerome, Benoit Debord
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Patent number: 9711867Abstract: A basic antenna (2), designed to form a radiating element of an array antenna, includes, superimposed, a planar reflector (4), a probe (6), and an assembly (8) of the EBG type by default in the form of a cavity (16). The basic antenna (2) includes a wall enclosure (10) capable of reflecting the electromagnetic waves at the operating frequency or frequencies of the basic antenna (2), the wall enclosure (10) being an extension in a direction orthogonal to the planar reflector (4) and simultaneously surrounding only the probe (6), the cavity (16) and the structure (14). The one- or two-dimensional array antenna includes a plurality of joined basic antennas (2) arranged compactly.Type: GrantFiled: December 20, 2012Date of Patent: July 18, 2017Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE DE LIMOGESInventors: Bernard Jecko, Mohammad Hajj, Regis Chantalat, Moustapha Salah Toubet
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Patent number: 9629872Abstract: The present invention relates to pharmaceutical compositions comprising sodium thiosulphate dispersed in a hydrophile-in-lipophile emulsion, and the use thereof for topical administration for the treatment of an ectopic calcification and/or of the consequences thereof in an individual, the sodium thiosulphate being in the form of a pharmaceutical composition comprising, in addition, a hydrophile-in-lipophile emulsion. The invention also relates to a method for preparing these pharmaceutical compositions.Type: GrantFiled: May 10, 2013Date of Patent: April 25, 2017Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE LIMOGES, CHU DE LIMOGES, UNIVERSITE PARIS-SUDInventors: Voa Ratsimbazafy, Jeremy Jost, Vincent Guigonis, Eric Caudron
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Patent number: 9590381Abstract: The invention relates to a laser oscillator comprising an amplifying optical fiber (MA) inserted in a resonant cavity so as to act as an active medium, and pumping means (DL, CP) causing a population inversion in said amplifying optical fiber, characterized in that said amplifying optical fiber comprises at least two cores (C1, C2) optically coupled to each other in a common cladding (G), and in that the shapes, sizes, refractive indices and the relative arrangement of said cores are chosen so that super-modes are supported, at least one (SMI) of which super-modes has, in an emission spectral band of said laser oscillator, a normal chromatic dispersion.Type: GrantFiled: April 4, 2012Date of Patent: March 7, 2017Assignees: Centre National de la Recherche Scientifique, Universite de Rouen, Universite de LimogesInventors: Ammar Hideur, Caroline Lecaplain, Sébastien Fevrier, Philippe Roy
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Publication number: 20160320316Abstract: Method for determining, in vitro, the cell aggressiveness grade of cancer cells or for detecting cancer stem cells in a cell sample originating from a solid tissue suspected of being cancerous, includes: a) dissociating the cell cluster constituting the sample into a suspension of whole and viable isolated cells, b) macroscopically sorting the cells to obtain homogeneous subpopulations, c) calibrating at least one microwave electromagnetic sensor resonating at its own resonance frequency, d) presenting the dissociated and sorted cells to the calibrated sensor, e) interrogating the sensor and determining its new resonance frequency having received the cells, f) calculating the variation in overall dielectric permittivity of the cells according to the variation in working frequency, which constitutes the electromagnetic signature of the cells. The macroscopic sorting is without prior labelling and is based on the intrinsic properties of the cells. A kit for implementing the method is also described.Type: ApplicationFiled: December 24, 2014Publication date: November 3, 2016Applicants: UNIVERSITE DE LIMOGES, ONCOMEDICSInventors: Arnaud POTHIER, Claire JEROME, Pierre BLONDY, Fabrice LALLOUE, Serge BATTU, Marie-Odile JAUBERTEAU, Philippe CARDOT, Christophe LAUTRETTE, Stephanie GIRAUD, Christophe MORAND DU PUCH
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Publication number: 20160264637Abstract: The present invention relates to a chimeric protein comprising at least one human amyloid P component and at least one fragment of an Fc region of a human antibody, the human amyloid P component and the fragment of an Fc region with which it is associated being bound to each other by means of a hinge region.Type: ApplicationFiled: October 31, 2014Publication date: September 15, 2016Applicants: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIO- TECHNOLOGIES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LIMOGESInventors: Christophe DE ROMEUF, Christophe SIRAC
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Publication number: 20160237574Abstract: Process for depositing a corrosion-protection coating on at least one portion of the surfaces of a metallic substrate having at least one cavity with an equivalent diameter emm<2 mm and a length/width ratio of greater than 150, using an aqueous suspension comprising powder of the metal to be deposited on the substrate combined with an agent for protecting the surface of the metal powder, a diluent, and at least one additive, the particles of the suspension each having an equivalent diameter d such that d?emm/10.Type: ApplicationFiled: September 17, 2014Publication date: August 18, 2016Applicants: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude, Centre National de la Recherche Scientifique, Universite de Limoges, Universite de LorraineInventors: Thierry CHARTIER, Pascal DEL-GALLO, Sebastien DOUBLET, Thierry MAZET, Laurent PROST, Nicolas RAMENATTE, Fabrice ROSSIGNOL, Michel VILASI
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Publication number: 20160157468Abstract: The invention relates to a transgenic non-human mammal comprising human immunoglobulin mu and epsilon heavy-chain constant transgenes C? and C? inserted in place of endogenous mu heavy-chain switch sequence S?, and its use for producing chimeric human immunoglobulin E antibodies specific for an antigen of interest.Type: ApplicationFiled: July 3, 2014Publication date: June 9, 2016Applicants: B Cell Design, Université de LimogesInventors: Michel Cogne, Brice Laffleur, Armelle Cuvillier, Marie Bosselut
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Patent number: 9270075Abstract: A supercontinuum source capable of emitting waves between the infrared range and the ultraviolet range, includes a pulsed laser source (12) capable of generating a laser beam and a non-linear microstructured optical fiber (14) capable of receiving the laser beam, in such a way that the supercontinuum source is capable of generating a beam (F?) over a pulse duration (T?), characterized in that the supercontinuum source includes elements for varying the pulse duration.Type: GrantFiled: April 8, 2011Date of Patent: February 23, 2016Assignees: UNIVERSITE DE LIMOGES, LEUKOS, MULTITELInventors: Philippe Leproux, Vincent Couderc, Yves Hernandez, Anthony Bertrand, Marco Andreana, Stephane Hilaire, Philippe Roy
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Patent number: 9256025Abstract: According to the invention, the intermediate sheath (13) is formed by assembling longitudinal elements (13A) and includes: a first optical material, the refractive index of which differs from the refractive index of the monomode core by at most 10?3; and a second optical material, the refractive index of which is lower than the refractive index of said monomode core and differs therefrom by at least 10?3.Type: GrantFiled: April 24, 2012Date of Patent: February 9, 2016Assignees: Centre National de la Recherche Scientifique, Universite de LimogesInventors: Philippe Roy, Kay Schuster, Stephan Grimm