Patents Assigned to Universite de Limoges
  • Publication number: 20190221992
    Abstract: A method and system for adjusting the profile of a laser wavefront formed by at least a laser beam to a desired laser wavefront profile, the laser beam or beams presenting random phases and intensities, comprises a mixing module, configured to generate, from interference phenomena among the laser beam or beams, a laser field, a second intensity measuring module configured to measure the mixed intensities of the laser field portions, a calculation unit configured to calculate one or several phase correction values of the phase of the laser beam or the phases of laser beams, from the intensities of the laser beams, the mixed intensities and one or several predetermined target phases, and a phase adjustment module configured to apply the phase correction value or values obtained from the calculation unit to the laser beam phases.
    Type: Application
    Filed: January 17, 2019
    Publication date: July 18, 2019
    Applicants: COMPAGNIE INDUSTRIELLE DES LASERS CILAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DE LIMOGES
    Inventors: Paul Armand, Jérémy Saucourt, Vincent Kermene, Agnès Desfarges-Berthelemot, Joël Benoist, Alain Barthelemy, Julien Leval
  • Patent number: 10243316
    Abstract: The invention relates to a method for triggering a pulsed light source, wherein it comprises at least one iteration of the following steps: receiving a control signal; determining what is called a separation time between the reception of said control signal and at least one preceding control signal; adjusting at least one control parameter of said pulsed light source depending at least on said separation; generating at least one electrical signal for triggering the pulsed light source depending on said at least one control parameter adjusted during the preceding step; and triggering the pulsed light source depending on said at least one triggering electrical signal.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: March 26, 2019
    Assignees: HORIBA ABX SAS, UNIVERSITE DE LIMOGES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Vincent Couderc, Roland Grando, Alexis Labruyere, Nelly Rongeat, Denisa Subtirelu
  • Publication number: 20190056373
    Abstract: A method for determination of the behavior of a reactive mixture intended for obtaining a geopolymer. The reactive mixture comprises at least one aluminosilicate material. The method includes determining a proportion of amorphous phase of the at least one aluminosilicate material and determining a degree of wettability of the at least one aluminosilicate material. If the proportion of amorphous phase is greater than 45% and if the degree of wettability is situated in a range between 300 ?g/l and 1400 ?g/l, then the reactive mixture, formed by the reaction of the at least one aluminosilicate material with an alkaline solution, forms a geopolymer.
    Type: Application
    Filed: October 27, 2016
    Publication date: February 21, 2019
    Applicants: UNIVERSITE DE LIMOGES, CNRS
    Inventors: Ameni Gharzouni, Laëticia Vidal, Sylvie Rossignol, Elodie Prud'Homme, Alexandre Autef, Emmanuel JOUSSEIN
  • Patent number: 10199177
    Abstract: The invention relates to a method for the synthesis of a nanocomposite compound comprising TiO2 nanoparticles bound to carbon nanostructures, characterized in that it comprises the following steps: a) mixing carbon nanostructures and at least one TiO2 precursor in a first liquid in order to form a stock suspension; b) nebulizing said stock suspension and transporting it into a reaction chamber by means of a gaseous flow; and c) carrying out laser pyrolysis of said stock suspension in said reaction chamber in order to simultaneously form TiO2 nanoparticles and graft them onto the nano structures.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: February 5, 2019
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LIMOGES
    Inventors: Nathalie Herlin, Jin Wang, Mathieu Pinault, Johann Boucle
  • Publication number: 20190027890
    Abstract: Some embodiments relate to a generation device that includes: a pulsed laser source generating primary photons having at least one wavelength within pulses having time dissymmetry, a forming device(s) controlling the primary photons so as to generate a selective-polarization, focused input beam, and an optical fiber wherein the primary photons induce secondary photons having different wavelengths resulting from a raman conversion cascade and forming a wide-spectrum output beam having substantially constant energy.
    Type: Application
    Filed: January 20, 2017
    Publication date: January 24, 2019
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LIMOGES
    Inventors: Christophe LOUOT, Dominique PAGNOUX, Katarzyna KRUPA, Badr SHALABY, Alexis LABRUYÈRE, Alessandro TONELLO, Vincent COUDERC
  • Publication number: 20180344760
    Abstract: The present invention concerns a treatment of diseases involving B cells, B lymphocytes or plasmocytes. In particular, it concerns an antisense oligonucleotide or a mixture of antisense oligonucleotides capable of inducing exon skipping at the RNA of the immunoglobulin heavy or light chains, for the use of same in the treatment of diseases involving B cells.
    Type: Application
    Filed: November 22, 2016
    Publication date: December 6, 2018
    Applicants: Universite de Limoges, Centre National de la Recherche Scientifique
    Inventors: Laurent Delpy, Nivine Srour, Michel Cogné
  • Patent number: 10116114
    Abstract: According to the invention, a plurality of elementary laser beams (fi) are generated, the phases of which are adjusted by an electro-optical feedback loop (6, 7i, 8i, 9) implementing the matrix equation of a phase-contrast filtering device (6).
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: October 30, 2018
    Assignees: COMPAGNIE INDUSTRIELLE DES LASERS CILAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE LIMOGES
    Inventors: Vincent Kermene, Agnes Desfarges-Berthelemot, Paul Armand, Joel Benoist, David Kabeya, Alain Barthelemy, David Sabourdy, Jean-Eucher Montagne
  • Patent number: 10053780
    Abstract: Process for depositing a corrosion-protection coating on at least one portion of the surfaces of a metallic substrate having at least one cavity with an equivalent diameter emm<2 mm and a length/width ratio of greater than 150, using an aqueous suspension comprising powder of the metal to be deposited on the substrate combined with an agent for protecting the surface of the metal powder, a diluent, and at least one additive, the particles of the suspension each having an equivalent diameter d such that d?emm/10.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: August 21, 2018
    Assignees: L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude, Centre National de la Recherche Scientifique, Université de Lorraine, Université de Limoges
    Inventors: Thierry Chartier, Pascal Del-Gallo, Sebastien Doublet, Thierry Mazet, Laurent Prost, Nicolas Ramenatte, Fabrice Rossignol, Michel Vilasi
  • Patent number: 10038441
    Abstract: A power switching cell with normally on field-effect transistors comprises a current switch receiving the control input signal over an activation input and a power transistor for switching a high voltage VDD applied to its drain, to its source that is connected to the output port of the cell. The control of the gate of the power transistor whose source is floating, according to the input signal, is provided by a self-biasing circuit connected between its gate and source. The current switch is connected between the self-biasing circuit and a zero or negative reference voltage. The self-biasing circuit comprises a transistor whose source or drain is connected to the gate or source of the power transistor. The gate of this transistor is biased by a resistor connected between its gate and source, and between the current switch and the source. The transistors are HEMT transistors using GaN or AsGa technology.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: July 31, 2018
    Assignees: THALES, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE DE LIMOGES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Olivier Jardel, Raymond Quere, Stéphane Piotrowicz, Philippe Bouysse, Sylvain Delage, Audrey Martin
  • Patent number: 9872483
    Abstract: The invention relates to a transgenic non-human mammal comprising human immunoglobulin mu and epsilon heavy-chain constant transgenes C? and C? inserted in place of endogenous mu heavy-chain switch sequence S?, and its use for producing chimeric human immunoglobulin E antibodies specific for an antigen of interest.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: January 23, 2018
    Assignees: B CELL DESIGN, UNIVERSITE DE LIMOGES
    Inventors: Michel Cogne, Brice Laffleur, Armelle Cuvillier, Marie Bosselut
  • Patent number: 9810837
    Abstract: A waveguide with a hollow core (16) delimited by a closed contour includes a succession of arcs (20) of negative curvature, each arc including a chord (24), characterized in that the contour of the hollow core (16) includes small arcs (PA) and large arcs (GA) arranged alternately, each arc (20) being symmetric with respect to a straight line passing through the center (18) of the hollow core (16) and the middle of the chord (24) thereof, the ratio b=2Ra/C of the large arcs being greater than 0.9 for the large arcs (GA), Ra corresponding to the maximum distance between the chord (24) and the arc (20), C corresponding to the length of the chord (24).
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: November 7, 2017
    Assignees: UNIVERSITE DE LIMOGES, CNRS, GLOPHOTONICS
    Inventors: Fetah Benabid, Frederic Gerome, Benoit Debord
  • Patent number: 9711867
    Abstract: A basic antenna (2), designed to form a radiating element of an array antenna, includes, superimposed, a planar reflector (4), a probe (6), and an assembly (8) of the EBG type by default in the form of a cavity (16). The basic antenna (2) includes a wall enclosure (10) capable of reflecting the electromagnetic waves at the operating frequency or frequencies of the basic antenna (2), the wall enclosure (10) being an extension in a direction orthogonal to the planar reflector (4) and simultaneously surrounding only the probe (6), the cavity (16) and the structure (14). The one- or two-dimensional array antenna includes a plurality of joined basic antennas (2) arranged compactly.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: July 18, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE DE LIMOGES
    Inventors: Bernard Jecko, Mohammad Hajj, Regis Chantalat, Moustapha Salah Toubet
  • Patent number: 9629872
    Abstract: The present invention relates to pharmaceutical compositions comprising sodium thiosulphate dispersed in a hydrophile-in-lipophile emulsion, and the use thereof for topical administration for the treatment of an ectopic calcification and/or of the consequences thereof in an individual, the sodium thiosulphate being in the form of a pharmaceutical composition comprising, in addition, a hydrophile-in-lipophile emulsion. The invention also relates to a method for preparing these pharmaceutical compositions.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: April 25, 2017
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE LIMOGES, CHU DE LIMOGES, UNIVERSITE PARIS-SUD
    Inventors: Voa Ratsimbazafy, Jeremy Jost, Vincent Guigonis, Eric Caudron
  • Patent number: 9590381
    Abstract: The invention relates to a laser oscillator comprising an amplifying optical fiber (MA) inserted in a resonant cavity so as to act as an active medium, and pumping means (DL, CP) causing a population inversion in said amplifying optical fiber, characterized in that said amplifying optical fiber comprises at least two cores (C1, C2) optically coupled to each other in a common cladding (G), and in that the shapes, sizes, refractive indices and the relative arrangement of said cores are chosen so that super-modes are supported, at least one (SMI) of which super-modes has, in an emission spectral band of said laser oscillator, a normal chromatic dispersion.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: March 7, 2017
    Assignees: Centre National de la Recherche Scientifique, Universite de Rouen, Universite de Limoges
    Inventors: Ammar Hideur, Caroline Lecaplain, Sébastien Fevrier, Philippe Roy
  • Publication number: 20160320316
    Abstract: Method for determining, in vitro, the cell aggressiveness grade of cancer cells or for detecting cancer stem cells in a cell sample originating from a solid tissue suspected of being cancerous, includes: a) dissociating the cell cluster constituting the sample into a suspension of whole and viable isolated cells, b) macroscopically sorting the cells to obtain homogeneous subpopulations, c) calibrating at least one microwave electromagnetic sensor resonating at its own resonance frequency, d) presenting the dissociated and sorted cells to the calibrated sensor, e) interrogating the sensor and determining its new resonance frequency having received the cells, f) calculating the variation in overall dielectric permittivity of the cells according to the variation in working frequency, which constitutes the electromagnetic signature of the cells. The macroscopic sorting is without prior labelling and is based on the intrinsic properties of the cells. A kit for implementing the method is also described.
    Type: Application
    Filed: December 24, 2014
    Publication date: November 3, 2016
    Applicants: UNIVERSITE DE LIMOGES, ONCOMEDICS
    Inventors: Arnaud POTHIER, Claire JEROME, Pierre BLONDY, Fabrice LALLOUE, Serge BATTU, Marie-Odile JAUBERTEAU, Philippe CARDOT, Christophe LAUTRETTE, Stephanie GIRAUD, Christophe MORAND DU PUCH
  • Publication number: 20160264637
    Abstract: The present invention relates to a chimeric protein comprising at least one human amyloid P component and at least one fragment of an Fc region of a human antibody, the human amyloid P component and the fragment of an Fc region with which it is associated being bound to each other by means of a hinge region.
    Type: Application
    Filed: October 31, 2014
    Publication date: September 15, 2016
    Applicants: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIO- TECHNOLOGIES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LIMOGES
    Inventors: Christophe DE ROMEUF, Christophe SIRAC
  • Publication number: 20160237574
    Abstract: Process for depositing a corrosion-protection coating on at least one portion of the surfaces of a metallic substrate having at least one cavity with an equivalent diameter emm<2 mm and a length/width ratio of greater than 150, using an aqueous suspension comprising powder of the metal to be deposited on the substrate combined with an agent for protecting the surface of the metal powder, a diluent, and at least one additive, the particles of the suspension each having an equivalent diameter d such that d?emm/10.
    Type: Application
    Filed: September 17, 2014
    Publication date: August 18, 2016
    Applicants: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude, Centre National de la Recherche Scientifique, Universite de Limoges, Universite de Lorraine
    Inventors: Thierry CHARTIER, Pascal DEL-GALLO, Sebastien DOUBLET, Thierry MAZET, Laurent PROST, Nicolas RAMENATTE, Fabrice ROSSIGNOL, Michel VILASI
  • Publication number: 20160157468
    Abstract: The invention relates to a transgenic non-human mammal comprising human immunoglobulin mu and epsilon heavy-chain constant transgenes C? and C? inserted in place of endogenous mu heavy-chain switch sequence S?, and its use for producing chimeric human immunoglobulin E antibodies specific for an antigen of interest.
    Type: Application
    Filed: July 3, 2014
    Publication date: June 9, 2016
    Applicants: B Cell Design, Université de Limoges
    Inventors: Michel Cogne, Brice Laffleur, Armelle Cuvillier, Marie Bosselut
  • Patent number: 9270075
    Abstract: A supercontinuum source capable of emitting waves between the infrared range and the ultraviolet range, includes a pulsed laser source (12) capable of generating a laser beam and a non-linear microstructured optical fiber (14) capable of receiving the laser beam, in such a way that the supercontinuum source is capable of generating a beam (F?) over a pulse duration (T?), characterized in that the supercontinuum source includes elements for varying the pulse duration.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: February 23, 2016
    Assignees: UNIVERSITE DE LIMOGES, LEUKOS, MULTITEL
    Inventors: Philippe Leproux, Vincent Couderc, Yves Hernandez, Anthony Bertrand, Marco Andreana, Stephane Hilaire, Philippe Roy
  • Patent number: 9256025
    Abstract: According to the invention, the intermediate sheath (13) is formed by assembling longitudinal elements (13A) and includes: a first optical material, the refractive index of which differs from the refractive index of the monomode core by at most 10?3; and a second optical material, the refractive index of which is lower than the refractive index of said monomode core and differs therefrom by at least 10?3.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: February 9, 2016
    Assignees: Centre National de la Recherche Scientifique, Universite de Limoges
    Inventors: Philippe Roy, Kay Schuster, Stephan Grimm