Patents Assigned to Universite de Reim Champagne-Ardenne
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Patent number: 11890761Abstract: A method for interconnecting a first robot with at least one second robot, each robot including at least: a first program, a second program, a third program, the method including the following steps, implemented by the second program after reception of a first message from the third program: conversion of the first message into a second message, the second message being formatted according to a predefined object structure including a field typ_msg indicating a type of the message amongst the types: command, query, or information; transmission of the second message to at least one program amongst: a first program belonging to the same robot, a second program of another robot.Type: GrantFiled: February 14, 2019Date of Patent: February 6, 2024Assignee: UNIVERSITÉ DE REIMS CHAMPAGNE-ARDENNEInventors: Marwane Ayaida, Nadhir Messai, Frédéric Valentin, Dimitri Marcheras, Lissan Afilal
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Publication number: 20240024527Abstract: A non-thermal plasma cleaning device including: an enclosure including an input port for fluid connection with a gas supply; a radio-wave source; a controller configured to successively perform, during a cleaning step, at least two, preferably at least three, non-thermal plasma generation cycles each including: controlling the radio-wave source to be in an active state during a first predetermined duration to generating a non-thermal plasma in the enclosure; and controlling the radio-wave source to be in an inactive state during a second predetermined duration, the input port being in an open state at least during the second predetermined duration.Type: ApplicationFiled: July 22, 2022Publication date: January 25, 2024Applicants: AURORA, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNEInventors: Thomas PARIAS, Florian LE BRAS, Marie-Paule GELLÉ
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Patent number: 11828652Abstract: A method for characterizing a sample using spectral images of the sample. At least one volume of values of an observed parameter is generated from the images for a plurality of coordinates of the pixels of the images and a plurality of acquisitions. At least one set of input data from the volume is extracted, with the input data corresponding to the values of the parameter, for a pixel of given coordinates in various acquisitions, to which values at least one conversion function has been applied. The at least one neural network is trained using the input data in order to extract therefrom at least one feature of the sample to be characterized. The at least one feature extracted by the neural network is used to perform a classification of the input data into a plurality of classes, each class being representative of at least one feature of the sample.Type: GrantFiled: November 30, 2018Date of Patent: November 28, 2023Assignees: UNIVERSITE DE REIMS CHAMPAGNE ARDENNE, CRITT-MDTSInventors: Valeriu Vrabie, Eric Perrin, Sihem Mezghani
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Patent number: 11820780Abstract: A process for manufacturing chromenes intended for the preparation of thermosetting resins, includes transforming an aromatic propargyl ether of general formula (I) into a chromene by homogeneous gold(I) catalysis with the catalyst (acetonitrile)[(2-biphenyl)di-tert-butylphosphine]gold(I) hexafluoroantimonate in an organic solvent under an inert or non-inert atmosphere. Moreover, a process for preparing a material made of thermoset resin, includes successively a) implementation of the above process; polymerization of the reaction product obtained in step a) so as to obtain the material made of thermoset resin; c) recovery of the material made of thermoset resin obtained in step b).Type: GrantFiled: July 23, 2020Date of Patent: November 21, 2023Assignees: ARIANEGROUP SAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNEInventors: Robin Pouyet, Xavier Coqueret, Brigitte Defoort, Bastien Rivieres
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Patent number: 11739097Abstract: A process for producing chromenes intended for the preparation of thermosetting resins, includes converting an aromatic propargyl ether of general formula (I) into a chromene by homogeneous catalysis with copper salts in anisole at a temperature between 100 and 170° C. Moreover, a process for preparing a material made of thermoset resin, includes successively a) carrying out the above process; b) polymerizing the reaction product obtained in a) so as to obtain the material made of thermoset resin; c) recovering the material made of thermoset resin obtained in b).Type: GrantFiled: July 23, 2020Date of Patent: August 29, 2023Assignees: ARIANEGROUP SAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNEInventors: Robin Pouyet, Xavier Coqueret, Brigitte Defoort, Bastien Rivieres
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Publication number: 20230207070Abstract: This method comprises: obtaining first data representative of amounts of a first gas and second data representative of amounts of a second tracer gas emitted by the source together with the first gas, calculating at least one coefficient of correlation between the amounts of the first gas and the amounts of the second gas from the first representative data and the second representative data; obtaining a measured or computed flow of the second gas emitted by the source; computing a flow of the first gas emitted by the source on the basis of the measured or computed flow of the second gas emitted by the source and the correlation coefficient.Type: ApplicationFiled: May 19, 2021Publication date: June 29, 2023Applicants: Centre national de la recherche scientifique, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE, TotalEnergies OneTechInventors: Ludovic DONNAT, Olivier DUCLAUX
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Publication number: 20230160789Abstract: This method comprises the following steps retrieving data about amounts of at least one gas, said data being measured in the atmosphere at a distance from the source along a plurality of lines parallel to a first direction; integrating the amounts read on each line in the first direction in order to obtain an integrated overall amount on each line; integrating the product of the integrated overall amounts on each line and a wind speed present on the line in a second direction perpendicular to the first direction, in order to obtain a raw flow of gas; determining the flow of gas emitted by the source based on the raw flow of gas.Type: ApplicationFiled: April 8, 2021Publication date: May 25, 2023Applicants: Centre national de la recherche scientifique, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE, TotalEnergies OneTechInventors: Ludovic DONNAT, Olivier DUCLAUX
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Publication number: 20230146441Abstract: This drone comprises a sensor for measuring representative data, comprising at least one measurement cell that is open to the atmosphere, at least a first laser source configured to inject, into the measurement cell, a first laser beam at a first wavelength characteristic of a first gas to be detected and a second laser source configured to inject, into the measurement cell, a second laser beam at a second wavelength characteristic of a second gas to be detected. The measuring sensor comprises a detector common to the two laser sources, said detector being configured to detect a first measurement signal originating from the measurement cell and resulting from injection of the first laser beam into the measurement cell and a second measurement signal originating from the measurement cell and resulting from injection of the second laser beam into the measurement cell.Type: ApplicationFiled: March 25, 2021Publication date: May 11, 2023Applicants: Centre national de la recherche scientifique, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE, TotalEnergies OneTechInventors: Ludovic DONNAT, Abel MAUNOURY, Lilian JOLY, Thomas DECARPENTERIE, Jérémie BURGALAT, Nicolas CHAUVIN, Grégory ALBORA, Nicolas DUMELIE, Julien COUSIN
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Publication number: 20230130737Abstract: The present invention is situated in the field of multimers used for targeted therapies. More particularly, the invention relates to methods for preparing multifunctional heteromultimeric protein complexes with a defined ratio of functional components and to multifunctional heteromultimeric protein complexes for directing complement-dependent cytolysis, optionally comprising a scaffold, which display three or more different functional components present in a defined relative ratio, of which one is a tracking component.Type: ApplicationFiled: November 2, 2022Publication date: April 27, 2023Applicants: Luxembourg Institute of Health (LIH), Université de Reims Champagne Ardenne URCAInventors: Xavier Dervillez, Carole Devaux, Jacques H.M. Cohen
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Patent number: 11591343Abstract: A process for manufacturing chromenes which are intended for the preparation of thermosetting resins, includes transforming an aromatic propargyl ether of general formula (I) into a chromene by flash vacuum thermolysis, at a temperature of between 300 and 600° C., at a pressure of between 4 and 10,000 Pa. It also concerns a process for preparing a material made of thermoset resin, including successively: a) implementation of the above process; b) polymerization of the reaction product obtained in a) so as to obtain the material made of thermoset resin; c) recovery of the material made of thermoset resin obtained in b).Type: GrantFiled: July 23, 2020Date of Patent: February 28, 2023Assignees: ARIANEGROUP SAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNEInventors: Robin Pouyet, Xavier Coqueret, Brigitte Defoort, Bastien Rivieres
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Patent number: 11525008Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of lung cancer. The inventors showed that FHIT (also known as bis(5-adenosyl)-triphosphatase) regulates HER2 activity in lung tumor cells and that HER2 inhibitors reduce invasion induced by FHIT inhibition. In particular, the present invention relates to a method of treating lung cancer in a patient in need thereof comprising the steps of i) determining the expression level of FHIT in a tumor tissue sample obtained from the patient, ii) comparing the expression level determined at step i) with a predetermined reference value and iii) administering to the patient a therapeutically effective amount of at least one HER2 inhibitor when the expression level determined at step i) is lower than the predetermined reference level.Type: GrantFiled: September 21, 2017Date of Patent: December 13, 2022Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE REIMS CHAMPAGNE-ARDENNE, CENTRE HOSPITALIER UNIVERSITAIRE DE REIMSInventors: Béatrice Raby, Amina Jouida, Myriam Polette
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Patent number: 11518791Abstract: The present invention is situated in the field of multimers used for targeted therapies. More particularly, the invention relates to methods for preparing multifunctional heteromultimeric protein complexes with a defined ratio of functional components and to multifunctional heteromultimeric protein complexes for directing complement-dependent cytolysis, optionally comprising a scaffold, which display three or more different functional components present in a defined relative ratio, of which one is a tracking component.Type: GrantFiled: May 22, 2017Date of Patent: December 6, 2022Assignees: Luxembourg Institute of Health (LIH), Université de Reims Champagne Ardenne URCAInventors: Xavier Dervillez, Carole Devaux, Jacques H. M. Cohen
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Patent number: 10829581Abstract: The invention relates to a curable resin that represents an excellent substitute for phenolic resins and is therefore able to replace phenolic resins in all applications in which they are used. Said resin is characterised in that it comprises: (1) at least one prepolymer resulting from the prepolymerisation of a compound A comprising at least one aromatic or heteroaromatic ring, a first group —O—CH2-C?CH and at least one second group selected from the groups —O—CH2-C?CH2 and —CH2-CH?CH2, said groups being carried by the at least one aromatic or heteroaromatic ring; and (2) a compound B comprising at least two thiol groups (—SH). The invention also relates to a material obtained by curing said curable resin, and in particular to an ablative composite material. The invention further relates to a material obtained by curing said curable resin.Type: GrantFiled: January 26, 2017Date of Patent: November 10, 2020Assignees: ARIANEGROUP SAS, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Bastien Rivieres, Brigitte Defoort, Cécile Lesamber, Xavier Coqueret
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Patent number: 10745530Abstract: A sizing composition for reinforcing fibres is provided which makes it possible to improve the adhesion of these fibres with respect to an organic matrix that forms, with them, a part made of a composite material and that results from the chain transfer polymerization of a curable resin. The sizing composition includes a polybutadiene prepolymer comprising at least two epoxide functions, a cross-linking agent comprising at least two reactive functions, at least one of which is a thiol function; and a catalyst comprising at least one tertiary amine function.Type: GrantFiled: February 11, 2015Date of Patent: August 18, 2020Assignees: AIRBUS SAFRAN LAUNCHERS SAS, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Arnaud Martin, Brigitte Defoort, Xavier Coqueret
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Patent number: 10673633Abstract: Method for retrieving data entered during a server connection, the server having access to a memory including a generated hashed word of a first input data, which corresponds to the data modified by a processing function, the capacity of the hashed word being lower than a predefined capacity, a generated security key of a second input data, which corresponds to the data modified by a processing function, the capacity of the security key being equal to the difference between the predefined capacity and the hashed word capacity, the security key not being stored, method wherein: —after a request to retrieve the data, the hashed word and the security key are concatenated in order to reach the predefined capacity, and —an inverse hash function, using an algebraic solving of the hash function, is applied to the concatenation of the hashed word and security key, to retrieve the data.Type: GrantFiled: March 23, 2016Date of Patent: June 2, 2020Assignees: UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE, UNIVERSITE DE PICARDIE JULES VERNEInventors: Gilles Dequen, Florian Legendre, Michaël Krajecki
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Publication number: 20190382458Abstract: The present invention is situated in the field of multimers used for targeted therapies. More particularly, the invention relates to methods for preparing multifunctional heteromultimeric protein complexes with a defined ratio of functional components and to multifunctional heteromultimeric protein complexes for directing complement-dependent cytolysis, optionally comprising a scaffold, which display three or more different functional components present in a defined relative ratio, of which one is a tracking component.Type: ApplicationFiled: May 22, 2017Publication date: December 19, 2019Applicants: Luxembourg Institute of Health (LIH), Université de Reims Champagne Ardenne URCAInventors: Xavier Dervillez, Carole Devaux, Jacques H.M. Cohen
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Patent number: 10155065Abstract: The subject matter of the present invention is a photopolymerizable liquid composition comprising at least one epoxidized polybutadiene prepolymer, at least one cationic photoinitiator, and at least one thioxanthone-derived photosensitizer, which can, for example, be in the form of a liquid dressing. The subject matter of the invention is also a process for obtaining a polymerized film from said photopolymerizable liquid composition, characterized in that said composition is applied to tissues such as the skin, the skin appendages or the mucous membranes so as to form a uniform liquid film, and the film thus obtained is subjected to ultraviolet radiation, preferably ultraviolet-visible radiation having a wavelength of between 380 and 405 nm, preferably between 385 and 395 nm.Type: GrantFiled: December 12, 2014Date of Patent: December 18, 2018Assignees: LABORATORIES URGO, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE, CENTER NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Xavier Coqueret, Sadananda Das, Stéphane Auguste
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Patent number: 9810625Abstract: A method for detecting and quantifying fibrosis, which involves at least; positioning a non-colored fixed tissue sample on a support; carrying out infrared acquisition, by scanning, of points of the sample; converting the infrared spectrum produced by each acquired point into at least one spectral image; carrying out a digital processing operation on the spectral image by distinguishing between at least physiological collagen and pathological collagen from fibrosis, attributing, to each point, a spectral class defined by an algorithm classifying the spectra according to the spectral similarities % thereof, then attributing a status to each class by statistically comparing with a digital model of spectra; quantifying the relative surface area occupied by the points of each status; and recording the result.Type: GrantFiled: July 2, 2015Date of Patent: November 7, 2017Assignee: UNIVERSITE DE REIMS CHAMPAGNE-ARDENNEInventors: Vincent Vuiblet, Olivier Piot, Philippe Rieu, Michael Fere, Cyril Gobinet
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Patent number: 9682929Abstract: The invention relates to new ?-vinyl carbonylated compounds corresponding to general formula (I), wherein R1, R2,R3, R4, R5 and Y are as defined in claim 1, their isomers, their diastereoisomers and acid addition salts or a pharmaceutically acceptable base. The invention also relates to a method for producing said compounds (I). It further relates to the use of said compound (I) as selective metalloprotease inhibitors, especially matrix metalloproteases 12 (MMP-12) and/or 9 (MMP-9). The compounds (I) are particularly useful for the prevention and/or treatment of chronic obstructive pulmonary disease (COPD), particularly emphysema induced by cigarette smoke.Type: GrantFiled: September 2, 2014Date of Patent: June 20, 2017Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, UNIVERSITE DE REIMS CHAMPAGNE-ARDENNEInventors: Samir Bouzbouz, Xavier Pannecoucke, Azzaq Belaaouaj, Laurette Malleret, Clement Denhez, Dominique Guillaume
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Patent number: 9675628Abstract: The method for producing a mixture of neutral oligosaccharides extracted from flaxseed includes oligosaccharides having high molar masses generated by fractionation by ultrafiltration at a cut-off of between 15,000 and 50,000 Da and between 5,000 and 15,000 Da. The mixture of oligosaccharides produced as a result of the implementation of the method, and to the applications of the mixture can be used for skin repair and skin aging control.Type: GrantFiled: April 24, 2014Date of Patent: June 13, 2017Assignees: UNIVERSITE DE REIMS CHAMPAGNE ARDENNE, CENTRE VALORISATION GLUCIDES PROD NAT, UNIVERSITE DE ROUEN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Francois Maquart, Georges Bellon, Claire Marchal, Helene Ducatel, Olivier Dupuis, Luc Picton, Didier Lecerf, Renauld Forbice