Patents Assigned to Universite du Droit et de la Sante de Lille
  • Patent number: 9593313
    Abstract: The present invention relates to a product selected from a protein, a fragment of the protein, a derived sequence and a homologous sequence of the protein, the protein including or being constituted by the 28 kDa glutathione S-transferase protein from a schistosome selected from Schistosoma haematobium, Schistosoma mansoni, Schistosoma bovis represented respectively by the sequences SEQ ID NO: 1, SEQ ID NO: 2 and SEQ ID NO: 3 for the use thereof in the treatment of an inflammatory autoimmune disease generating a response of type Th1 and/or Th17.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: March 14, 2017
    Assignees: UNIVERSITE DU DROIT ET DE LA SANTE DE LILLE 2, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE LILLE
    Inventors: Monique Capron, Mohamed El Nady, Jean-Frederic Colombel, Gilles Riveau
  • Publication number: 20150118259
    Abstract: The present invention relates to a product selected from a protein, a fragment of the protein, a derived sequence and a homologous sequence of the protein, the protein including or being constituted by the 28 kDa glutathione S-transferase protein from a schistosome selected from Schistosoma haematobium, Schistosoma mansoni, Schistosoma bovis represented respectively by the sequences SEQ ID NO: 1, SEQ ID NO: 2 and SEQ ID NO: 3 for the use thereof in the treatment of an inflammatory autoimmune disease generating a response of type Th1 and/or Th17.
    Type: Application
    Filed: February 6, 2013
    Publication date: April 30, 2015
    Applicants: UNIVERSITE DU DROIT ET DE LA SANTE DE LILLE 2, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE LILLE
    Inventors: Monique Capron, Mohamed El Nady, Jean-Frederic Colombel, Gilles Riveau
  • Patent number: 8642315
    Abstract: Process for preserving insulin secreting cells intended to be transplanted, including the following steps: introducing an initial volume of culture medium and insulin-secreting cells into a culture container, providing a culture medium source, and replacing, at time intervals below 8 hours, the culture medium in the culture container with culture medium from the source so as to renew the culture medium contained in the container.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: February 4, 2014
    Assignees: Maco Pharma, Centre Hospitalier Regional Universitaire de Lille, Universite du Droit et de la Sante de Lille 2
    Inventors: Francois Pattou, Julie Kerr-Conte, Cecile Coissac Blondel, Bruno Lukowiak, Brigitte Vandewalle, Antoine Heron
  • Publication number: 20120003187
    Abstract: A method for preserving a preparation of insulin-secreting cells includes the step of placing the preparation of insulin-secreting cells in contact with a biological medium, the biological medium including a nutritive product including albumin, and further includes a peptone or a mixture of peptones in sufficient quantity to preserve the insulin-secreting cells.
    Type: Application
    Filed: May 5, 2011
    Publication date: January 5, 2012
    Applicants: MACO PHARMA, UNIVERSITE DU DROIT ET DE LA SANTE DE LILLE 2, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE LILLE
    Inventors: Julie Kerr-Conte, Bruno Delorme
  • Patent number: 7833699
    Abstract: The present invention concerns methods for in vitro detection of an infection by Mycobacterium tuberculosis in mammals, and methods for in vitro distinction between mammals infected with Mycobacterium tuberculosis in which the disease is declared (active form) and mammals which are infected but asymptomatic for tuberculosis (latent form), and a method for in vitro distinction between mammals presenting an active form of tuberculosis and mammals not infected by M. tuberculosis or presenting a latent form of tuberculosis. The present invention also pertains to kits for detection and distinction between infected mammals presenting tuberculosis symptoms and infected mammals with no disease development, and a kit for distinguishing between mammals presenting an active form of tuberculosis and mammals not infected by M. tuberculosis or presenting a latent form of tuberculosis.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: November 16, 2010
    Assignees: Institute Pasteur de Lille, Inserm (Institut National de la Sante Et de la Recherche Medicale), Universite Libre de Bruxelles, Universite du Droit Et de la Sante de Lille II
    Inventors: Camille Locht, Françoise Mascart, Stéphane Temmerman, Jean-Michel Hougardy, Sammy Place, Christian Sergheraert
  • Publication number: 20090286315
    Abstract: Process for preserving insulin secreting cells intended to be transplanted, including the following steps: introducing an initial volume of culture medium and insulin-secreting cells into a culture container, providing a culture medium source, and replacing, at time intervals below 8 hours, the culture medium in the culture container with culture medium from the source so as to renew the culture medium contained in the container.
    Type: Application
    Filed: May 15, 2009
    Publication date: November 19, 2009
    Applicants: MACO PHARMA, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE LILLE, UNIVERSITE DU DROIT ET DE LA SANTE DE LILLE 2
    Inventors: Francois Pattou, Julie Kerr-Conte, Cecile Coissac Blondel, Bruno Lukowiak, Brigitte Vandewalle, Antoine Heron
  • Patent number: 7441898
    Abstract: The eye is positioned relative to a detection device in such a manner as to co-operate with the device to form a Fabry-Perot cavity having a main optical axis and comprising two opposite reflecting faces on the main optical axis, one of these two faces being constituted by a stationary reflecting element and the other being formed by the cornea of the eye. An incident laser beam is injected into said cavity so as to be centered on the main optical axis of the Fabry-Perot cavity, the cornea is aligned laterally and longitudinally relative to the main optical axis in such a manner as to obtain longitudinal interference between the go and the return laser beams reflected between the two reflecting faces of the cavity, and an optoelectronic detector is used to detect the intensity I of said interference as a function of time. The invention is applicable to measuring intraocular pressure.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: October 28, 2008
    Assignees: Centre Hospitalier Regional Universitaire de Lille, Universite des Sciences et Technologies de Lille, Universite du Droit et de la Sante de Lille
    Inventors: Jaouad Zemmouri, Patrick Dubois, Pierre-Paul Elena, Jean-François Rouland, Alexis Debut
  • Publication number: 20080038776
    Abstract: The present invention relates to a method for the preparation of a macromolecule produced by bacteria of the Bifidobacterium breve I-2219 strain and the use of the said macromolecule for the preparation of medicines designed for the prevention and treatment of inflammatory rheumatic disease.
    Type: Application
    Filed: October 14, 2005
    Publication date: February 14, 2008
    Applicant: UNIVERSITE DU DROIT ET DE LA SANTE DE LILLE
    Inventors: Marie-Benedicte ROMOND, Marie-Francoise ODOU-PARIS, Elisabeth SINGER
  • Publication number: 20070212740
    Abstract: The present invention concerns methods for in vitro detection of an infection by Mycobacterium tuberculosis in mammals, and methods for in vitro distinction between mammals infected with Mycobacterium tuberculosis in which the disease is declared (active form) and mammals which are infected but asymptomatic for tuberculosis (latent form), and a method for in vitro distinction between mammals presenting an active form of tuberculosis and mammals not infected by M. tuberculosis or presenting a latent form of tuberculosis. The present invention also pertains to kits for detection and distinction between infected mammals presenting tuberculosis symptoms and infected mammals with no disease development, and a kit for distinguishing between mammals presenting an active form of tuberculosis and mammals not infected by M. tuberculosis or presenting a latent form of tuberculosis.
    Type: Application
    Filed: December 28, 2006
    Publication date: September 13, 2007
    Applicants: Institut Pasteur de Lille, Inserm (institut National de la Sante et de la Recherche Medicale), Universite Libre de Bruxelles, Universite du Droit et de la Sante de Lille II
    Inventors: Camille Locht, Francoise Mascart, Stephane Temmerman, Jean-Michel Hougardy, Sammy Place, Christian Sergheraert