Patents Assigned to UNIVERSITE DU MANS
  • Patent number: 12233041
    Abstract: Compounds of general formula: wherein R0A and R0B are independently selected from hydrogen and pharmaceutically acceptable cations; and RA and RB are identical and selected from amide, carbamate, sulphonamide, azido, cyano and halide. Also, a pharmaceutical composition including one of the compounds. The composition may also include another active ingredient, especially an antineoplastic agent. Further a compound or a composition for use as a medicament, especially a compound or a composition for use in the treatment of a proliferative disease such as for example cancer.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: February 25, 2025
    Assignees: UNIVERSITÉ DE NANTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DU MANS
    Inventors: Fabrice Fleury, Alexandre Demeyer, Pierre Weigel, Benoit Chenais, Monique Mathé, Jacques Lebreton
  • Patent number: 12181415
    Abstract: A method for identifying a microorganism to be identified, which includes the following steps: obtaining an Excitation-Emission EEM of the microorganism to be identified, analysing the main components of the EEM matrix using at least one reference EEMr matrix, projecting the result of the analysis onto a plane defined by two main components, and identifying the microorganism to be identified.
    Type: Grant
    Filed: November 27, 2020
    Date of Patent: December 31, 2024
    Assignees: UNIVERSITE DU MANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS-, CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS, UNIVERSITE D'ANGERS
    Inventors: Jean-François Bardeau, Jean-Philippe Bouchara
  • Publication number: 20240239025
    Abstract: Embodiments of the present invention relates to an acoustic metamaterial, as well as to a method for manufacturing the same. The acoustic metamaterial includes a plurality of channels or columns each having the same cross-section with a hydraulic radius between 5 and 300 ?m, which channels or columns are arranged with a periodic spacing between 2 and 600 ?m. This results in a highly dense network that can provide optimal acoustic absorption and/or impedance over a wide frequency range. The method for manufacturing the same includes additive manufacturing with a plurality of consecutive material deposition steps to form, in each step, a layer comprising a plurality of periodically repeated cells separated by walls. The layers deposited in the consecutive material deposition steps are stacked with their respective cells aligned to form channels.
    Type: Application
    Filed: May 3, 2022
    Publication date: July 18, 2024
    Applicants: SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU MANS
    Inventors: Josué COSTA BAPTISTA, Edith-Roland FOTSING, Annie ROSS, Jacky Novi MARDJONO, Jean BOULVERT, Daniel THERRIAULT
  • Patent number: 11988168
    Abstract: Resonating patch for acoustic treatment comprising a resonant plate, a transducer and an electrical circuit electrically connected to the transducer, the resonant plate comprising a peripheral strip extending along the perimeter of the resonant plate. The patch comprises cutouts together defining deformable lamellae having at least one end connected to the peripheral strip.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: May 21, 2024
    Assignees: SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU MANS
    Inventors: Josselin David Florian Regnard, Thibault Abily, Stéphane Bernard Durand
  • Patent number: 11785391
    Abstract: A micrometric speaker includes a frame, an electromechanical transducer, and a mechanical-acoustic transducer comprising a rigid plate movably mounted in the frame. The electromechanical transducer comprises two piezoelectric actuators and two elastic strips. The frame comprises a central crossmember from which the two strips extend until engaging two lateral coupling edges of the mechanical-acoustic transducer, and the mechanical-acoustic transducer comprises two linearising springs each extending from one of the lateral edges to the rigid plate, to enable, during a deformation of the strips, a movement of the two lateral edges to the central crossmember and reduce the longitudinal constraints applied to the strips during their deformation due to their “recessed-guided” bending configuration.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: October 10, 2023
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU MANS
    Inventors: Romain Liechti, Fabrice Casset, Thierry Hilt, Stephane Durand
  • Patent number: 11635367
    Abstract: A contrast-amplifying carrier for observing a sample, includes a transparent substrate bearing at least one absorbent coating suitable for behaving as an antireflection coating when it is illuminated at normal incidence at an illumination wavelength ? through the substrate and when the face of the coating opposite the substrate is in contact with a medium referred to as a transparent ambient medium, the refractive index n3 of which is lower than that of the refractive index n0 of the substrate. The absorbent coating comprises: an absorbent sublayer referred to as the contrast sublayer, deposited on the surface of the transparent substrate; and an absorbent layer referred to as the sensitive layer, distinct from the contrast sublayer and comprising between 1 and 5 sheets of a graphene-type material. Methods for producing and for using such a contrast-amplifying carrier are also provided.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: April 25, 2023
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DU MANS, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Stéphane Campidelli, Renaud Cornut, Vincent Derycke, Dominique Ausserre, Manuel Ausserre
  • Patent number: 11614460
    Abstract: An electronic device for measuring a speed of flow of a fluid that includes at least two electroacoustic transducers adapted for emitting and/or receiving acoustic signals through the flow of the fluid, the electronic device being adapted for determining a measurement of the speed of flow of the fluid from the characteristics of an acoustic signal emitted and one or more acoustic signals received, these received acoustic signals corresponding to reflections of the emitted acoustic signal.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: March 28, 2023
    Assignees: UNIVERSITE DU MANS, ASSOC TRANSFERTS TECHNOLOGIES MANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Jacques Emery, Mohammed Tabellout, Charfeddine Mechri
  • Publication number: 20230003652
    Abstract: A method for identifying a microorganism to be identified, which includes the following steps: obtaining an Excitation-Emission EEM of the microorganism to be identified, analysing the main components of the EEM matrix using at least one reference EEMr matrix, projecting the result of the analysis onto a plane defined by two main components, and identifying the microorganism to be identified.
    Type: Application
    Filed: November 27, 2020
    Publication date: January 5, 2023
    Applicants: UNIVERSITE DU MANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -, UNIVERSITE D'ANGERS, CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS
    Inventors: Jean-François BARDEAU, Jean-Philippe BOUCHARA
  • Publication number: 20220412289
    Abstract: Resonating patch for acoustic treatment comprising a resonant plate, a transducer and an electrical circuit electrically connected to the transducer, the resonant plate comprising a peripheral strip extending along the perimeter of the resonant plate. The patch comprises cutouts together defining deformable lamellae having at least one end connected to the peripheral strip.
    Type: Application
    Filed: November 19, 2020
    Publication date: December 29, 2022
    Applicants: SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU MANS
    Inventors: Josselin David Florian REGNARD, Thibault ABILY, Stéphane Bernard DURAND
  • Publication number: 20220337954
    Abstract: A micrometric speaker includes a frame, an electromechanical transducer, and a mechanical-acoustic transducer comprising a rigid plate movably mounted in the frame. The electromechanical transducer comprises two piezoelectric actuators and two elastic strips. The frame comprises a central crossmember from which the two strips extend until engaging two lateral coupling edges of the mechanical-acoustic transducer, and the mechanical-acoustic transducer comprises two linearising springs each extending from one of the lateral edges to the rigid plate, to enable, during a deformation of the strips, a movement of the two lateral edges to the central crossmember and reduce the longitudinal constraints applied to the strips during their deformation due to their “recessed-guided” bending configuration.
    Type: Application
    Filed: April 15, 2022
    Publication date: October 20, 2022
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU MANS
    Inventors: Romain LIECHTI, Fabrice CASSET, Thierry HILT, Stephane DURAND
  • Publication number: 20220016068
    Abstract: Compounds of general formula: wherein R0A and R0B are independently selected from hydrogen and pharmaceutically acceptable cations; and RA and RB are identical and selected from amide, carbamate, sulphonamide, azido, cyano and halide. Also, a pharmaceutical composition including one of the compounds. The composition may also include another active ingredient, especially an antineoplastic agent. Further a compound or a composition for use as a medicament, especially a compound or a composition for use in the treatment of a proliferative disease such as for example cancer.
    Type: Application
    Filed: November 22, 2019
    Publication date: January 20, 2022
    Applicants: UNIVERSITÉ DE NANTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DU MANS
    Inventors: Fabrice FLEURY, Alexandre DEMEYER, Pierre WEIGEL, Benoit CHENAIS, Monique MATHÉ, Jacques LEBRETON
  • Publication number: 20210165017
    Abstract: An electronic device for measuring a speed of flow of a fluid that includes at least two electroacoustic transducers adapted for emitting and/or receiving acoustic signals through the flow of the fluid, the electronic device being adapted for determining a measurement of the speed of flow of the fluid from the characteristics of an acoustic signal emitted and one or more acoustic signals received, these received acoustic signals corresponding to reflections of the emitted acoustic signal.
    Type: Application
    Filed: April 19, 2019
    Publication date: June 3, 2021
    Applicants: UNIVERSITE DU MANS, ASSOC TRANSFERTS TECHNOLOGIES MANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Jacques EMERY, Mohammed TABELLOUT, Charfeddine Mechri
  • Patent number: 10824112
    Abstract: Some embodiments are directed to a system for measuring vibrations of a surface of a mechanical part, by digital holography. The system includes a source of radiation emitting in a predetermined range of frequencies, a first separator element configured to define a first incident ray and a reference ray, a module for shaping a second incident ray from the first incident ray, and an optical element configured to make the reference ray and a radiation produced by a reflection of the incident ray on the surface of the mechanical part interfere. The module for shaping the second incident ray includes diffracting optical elements having a diffraction structure to diffract the incident radiation. The structure is from a polymer, sol-gel or photoresin material resting against a glass substrate, the structure including elements etched in a plane parallel and/or orthogonal to the substrate, with dimensions from 100 nanometres to 100 micrometres.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: November 3, 2020
    Assignees: UNIVERSITE DU MANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT MINES TÉLÉCOM (IMT) ATLANTIQUE BRETAGNE PAYS DE LA LOIRE, INSTITUT DE RECHERCHE TECHNOLOGIQUE JULES VERNE
    Inventors: Julien Poittevin, Pascal Picart, Kevin Heggarty, Julien Le Meur
  • Patent number: 10705115
    Abstract: A method is provided for positioning a micro- or nano-object on a planar support by displacement performed under visual control, wherein the micro- or nano-object is immersed in a transparent medium, called ambient medium, having a refractive index n3; the planar support comprises a transparent substrate of refractive index n0>n3 on which is deposited at least one optically absorbent layer, adapted to behave as antireflection coating when it is lit at normal incidence with a lighting wavelength ? through the substrate; and the visual control comprises the lighting of the micro- or nano-object at least with the wavelength ? through the substrate, and the observation thereof also through the substrate. A method to scanning probe microscopy and to the assembly of nanostructures is provided.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: July 7, 2020
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DU MANS
    Inventors: Stéphane Campidelli, Renaud Cornut, Vincent Derycke, Dominique Ausserre, Manuel Ausserre
  • Patent number: 10562868
    Abstract: Disclosed are polyfunctional compounds of formula: as well as methods for preparing same and the uses thereof, in particular in orthogonal or bioorthogonal processes.
    Type: Grant
    Filed: July 4, 2017
    Date of Patent: February 18, 2020
    Assignee: UNIVERSITE DU MANS
    Inventors: Philippe Bertus, Laurent Fontaine, Morwenna Pearson-Long, Fabien Boeda, Julien Caille, Valentin Gaignet
  • Patent number: 10477302
    Abstract: A passive sound absorber includes a cavity opening to the outside via an input direction to form a Helmholtz resonator for a first frequency. The absorber further includes at least one moving element, or wafer, suspended or held by suspensions in a position obstructing the neck in a non-sealed manner. The relative stiffness of the suspensions and the wafer is determined so that the assembly resonates in a vibration in a “piston” movement at a second frequency different from the first frequency, achieving absorption for this second frequency or frequency range. A hybrid version includes a coil that is controlled to adjust the acoustic impedance of the absorber. An acoustic wall includes a plurality of such absorbers produced by a repetitive structure opening through perforations, each receiving such a wafer, and a method of designing and manufacturing such an absorber or wall is also provided.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: November 12, 2019
    Assignees: UNIVERSITE PARIS-SUD, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU MANS
    Inventors: Emile Martincic, Alexandre Houdouin, Stéphane Durand, Nourdin Yaakoubi, Elie Lefeuvre, Yves Auregan
  • Patent number: 9453843
    Abstract: Novel compounds, having an azlactone function, of formula (I), to be used as multifunctional coupling agents, and a method for coupling a biomolecule and a target molecule using such a compound are described. A diagnosis reagent, a kit for implementing the coupling method, a method for separating, detecting and/or characterizing at least one molecule of interest, and a composition including a novel compound are also described.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: September 27, 2016
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU MANS
    Inventors: Laurent Fontaine, The Hien Ho, Sagrario Pascual, Veronique Montembault