Abstract: A method is disclosed for continuously monitoring a blood pressure measurement using a sensor connected by a hydraulic link to an arterial catheter, the method includes determining the dynamic parameters of the link, analyzing the frequency content of the incident signal, detecting one of the following situations: (a) ability of the link to transmit the incident signal with a distortion below a threshold, (b) ability of the link to transmit the incident signal with a distortion above the threshold and possibility of correcting the measured signal, (c) inability of the link to transmit the incident signal with a distortion below the threshold and impossibility of correcting the measured signal, periodic application of a mechanical action to the tubing providing the hydraulic link.

Abstract: A device treats a region of the body of a patient having a cutaneous ulcer, including: a hydrogel, hydrocolloid, hydrocellular or hydrofiber primary dressing, impregnated with treprostinil, that can be shaped to the contours of the region to be treated, a so-called “active” electrode in contact with the primary dressing, a so-called “passive” electrode at a distance from the active electrode, a DC generator, the terminals of which are connected to the electrodes, the cathode and the anode respectively forming the active electrode and the passive electrode for iontophoresis, so as to cause treprostinil to migrate by cathodal iontophoresis into the region to be treated.

Abstract: A device positions and/or orients in the body of a patient, a surgical tool carried by a tool-holder, including a platform capable of being placed on the body of the patient, an orientable carrier, at least one part of which is rigidly connected to the tool-holder, means for guiding the orientable carrier rotationally relative to the platform in two directions of a plane parallel to the platform, at least 2 pneumatic actuators which engage with the orientable carrier such that a variation in pressure of at least one of the pneumatic actuators causes the orientable carrier to rotate in the first direction and/or the second direction, in which the pneumatic actuators are volumes that can deform in a predetermined direction as a function of the internal pressure.

Abstract: A method for producing a film including a non-magnetic matrix and a plurality of three-dimensional magnetic microstructures arranged within the matrix according to a predetermined pattern. The method includes providing a master substrate with a magnetically structured face formed from a plurality of magnetic field micro-sources, having a magnetic field gradient of between 102 and 106 T/m. The method also includes adding magnetic microparticles or nanoparticles to the magnetically structured face of the master substrate, the particles agglomerating into three-dimensional microstructures arranged under an effect of an attractive magnetophoretic force exerted by the magnetic field gradient on the surface of the master substrate. The method further includes depositing, on the magnetically structured face of the master substrate, a matrix made from a non-magnetic material, in such a way as to enclose the arranged microstructures and to form the film and peeling the film from the master substrate.

Abstract: A process of manufacturing component with a composite film including a matrix made of thermoplastic polymer and particles inside this matrix. This process includes heating the composite film in order for its temperature to exceed the glass transition temperature of its matrix, then when the composite film is softened, flattening an external face of the composite film by a smooth face resting directly over the whole of this external face, this smooth face forming part of the front face of a flexible membrane, the whole of the rear face of which, located on the side opposite the front face, is pushed against the composite film by a fluid, then cooling the composite film below the glass transition temperature, then withdrawing the membrane in order to mechanically separate its front face from the external face of the composite film.

Abstract: An image processing method enables an elasticity image of a body including a cavity to be produced on the basis of the material(s) forming the body, wherein the method includes the steps of: receiving a deformation image illustrating a field of movement of the points of the body on the basis of a pressure difference in the body, estimating a shape function of the body from the deformation image, calculating an elasticity image of the body on the basis of the shape function, of the pressure difference and of the deformation image.

Abstract: A supercapacitor to be submerged in a medium containing a biological material and an oxidant, wherein the anode comprises a first enzyme that can catalyse the oxidation of the biological material and the cathode comprises a second enzyme that can catalyse the reduction of the oxidant, and wherein each of the anode and cathode electrodes consists of a solid agglomerate of a conductive material mixed with the first or the second enzyme, said agglomerate having a specific surface that is larger than or equal to 20 m2/g and an average pore size varying between 0.7 nm and 10 pm.

Abstract: The invention relates to novel cyclodecapeptide compounds having formula (I) for use as drugs and, more specifically, for use in the diagnosis, prevention and/or treatment of neurodegenerative diseases, such as Wilson's disease and Alzheimer's disease, and for use in the diagnosis, prevention and/or treatment of poisoning with metal ions, such as copper and mercury ions. The invention also relates to pharmaceutical compositions comprising at least one compound having formula (I) as an active principle.

Abstract: The present invention relates to a method for producing a molecule of interest in bacteria which is based on a reversible growth arrest of the bacteria at the cellular growth global control system level, thus allowing an improved yield of production of said molecule of interest.

Abstract: The disclosure includes a coaxial microwave applicator for plasma production, including a coaxial tube formed by a central core and an outer conductor separated from the central core by an annular space allowing propagation of microwaves. The applicator includes: a cylindrical permanent magnet disposed at the end of the central core; and at least one annular permanent magnet disposed at the end of the outer conductor, all of the magnets disposed at the end of the coaxial tube having the same direction of magnetization. The magnetization of the magnets forms a magnetic field suitable for generating, in a zone away from the end of the applicator, an electronic cyclotronic resonance coupling with the electric microwave field of the applicator. The external radius and the magnetization of the annular magnet are selected such that the magnetic field lines generated by the magnets pass through the coupling zone in a direction substantially parallel to the axis of the applicator.

Abstract: The present disclosure relates to a method for identifying the presence or absence of anti-Toxoplasma gondii antibodies in a human or animal serum, including placing the previously drawn serum in contact with antigens capable of binding with the anti-Toxoplasma gondii antibodies, and the observation of a bond or of an absence of a bond of antibodies with the antigens, and a combination of two recombinant GRA2 and GRA6 proteins. In particular, the antigens are attached to a support, in particular an ELISA plate. This test is preferably carried out as a supplement to another test for diagnosing toxoplasmosis.

Abstract: The invention concerns a device for measuring parasitic movements in a sample (5) to be analysed in an X-ray tomography apparatus, the device comprising: a source (1) emitting an X-ray beam (6) to a detector (3), the sample, carried by a support (13), being traversed by the beam; and a sight (17) carrying at least three balls (21) that are opaque to X-rays, the sight being attached to said support such that, on the detector, images (25) of the balls are around an image (16) of the sample, the shape and the materials of the sight being chosen such that the positions of the balls relative to the support are insensitive to temperature variations.

Abstract: The disclosure includes a glow-discharge lamp including: an elongate casing transparent to illuminating radiation and containing a plasma gas; a device for applying an electric field for maintaining a plasma in the so-called positive column region of the casing, the device including two electrodes forming an anode and a cathode located in the casing at each end thereof; and a radio-frequency or microwave cathode plasma source arranged in the casing in relation to the cathode-forming electrode, such as to generate a high-frequency discharge located on the surface of the electrode in order to generate the plasma. The disclosure also includes a lighting method of such a glow-discharge lamp.

Abstract: The present disclosure relates to a minimally invasive surgical procedure device including a set for forming a modular surgical tool, the set including a carrier shaft and a plurality of functional modules, in which the each functional module has means for rigid connection to the carrier shaft and/or to another functional module and has dimensions suitable for insertion into the body of a patient through a trocar, wherein the device is characterized in that: —each functional module has at least one degree of rotational or translational freedom and/or a functional end-piece such as a forceps, hook or a scalpel, —the carrier shaft and/or the functional modules include means for actuating the functional modules according to the respective degree of freedom thereof and/or the respective function thereof, and in that the device includes an electromechanical interface capable of controlling the actuating of the assembled functional modules forming the tool.

Abstract: The invention relates to small cell penetrating peptides (CPP) derived from the scorpion toxin maurocalcine and to their use as vectors for the intracellular delivery of various drugs and agents.

Abstract: A process of manufacturing component with a composite film including a matrix made of thermoplastic polymer and particles inside this matrix. This process includes heating the composite film in order for its temperature to exceed the glass transition temperature of its matrix, then when the composite film is softened, flattening an external face of the composite film by a smooth face resting directly over the whole of this external face, this smooth face forming part of the front face of a flexible membrane, the whole of the rear face of which, located on the side opposite the front face, is pushed against the composite film by a fluid, then cooling the composite film below the glass transition temperature, then withdrawing the membrane in order to mechanically separate its front face from the external face of the composite film.

Abstract: A spacer including a first part made from a first shape memory material, and a second part made from a second shape memory material.

Abstract: The invention relates to a method for producing a component comprising a conductive grid insulated from a semiconductor monocrystalline diamond substrate by an insulating region, comprising the following steps: a) oxygenating the surface of the substrate so as to replace the hydrogen surface terminations of the substrate with oxygen surface terminations; and b) forming the insulating region on the surface of the substrate by repeated monatomic layer deposition.

Abstract: The invention relates to a matrix device for measuring characteristics of an X-ray beam. The device includes a first set of detection cells of a size different from the cells of at least one second set of detection cells. Each cell corresponds to an ionization chamber including a detection electrode. The detection electrodes of all the cells have the same effective surface for collecting charges.

Abstract: The present disclosure relates to a surgical instrument for sampling molecules in an organ which can be accessed directly or via a surgical portal, including: a device for capturing the molecules, a stylet supporting the capture device, capable of entering the organ, a guide for inserting the stylet into the body as far as the organ, wherein the distal end of the guide is provided with a damping block intended to come to bear upon the organ.