Patents Assigned to Universite Paris 7
-
Patent number: 8361908Abstract: The use of at least one diazonium salt bearing an initiator function, for forming an undercoat obtained by grafting a graft derived from the diazonium salt and bearing an initiator function at the surface of a conductive or semiconductive material on the undercoat, and for forming on the undercoat a polymeric layer obtained by polymerization, in particular free radical polymerization, in situ of at least one monomer, initiated from the initiator function.Type: GrantFiled: September 23, 2011Date of Patent: January 29, 2013Assignees: Universite Paris 7-Denis Diderot, AlchimedicsInventors: Mohamed Mehdi Chehimi, Jean Pinson, Bernadette Charleux, Christophe Bureau, Christopher Tronche, Tarik Matrab, Christian Perruchot, Eva Cabet-Deliry, Maud Save
-
Patent number: 8343718Abstract: The invention relates to a novel strain of severe acute respiratory syndrome (SARS)-associated coronavirus, resulting from a sample collected in Hanoi (Vietnam), reference number 031589, nucleic acid molecules originating from the genome of same, proteins and peptides coded by said nucleic acid molecules and, more specifically, protein N and the applications thereof, for example, as diagnostic reagents and/or as a vaccine.Type: GrantFiled: April 6, 2010Date of Patent: January 1, 2013Assignees: Institut Pasteur, Centre National de la Recherche Scientifique, Universite Paris 7Inventors: Sylvie Van Der Werf, Nicolas Escriou, Bernadette Crescenzo-Chaigne, Jean-Claude Manuguerra, Frederik Kunst, Benoît Callendret, Jean-Michel Betton, Valérie Lorin, Sylvie Gerbaud, Ana Maria Burguiere, Saliha Azebi, Pierre Charneau, Frédéric Tangy, Chantal Combredet, Jean-François Delagneau, Monique Martin
-
Patent number: 8338169Abstract: A cell/ligand specific marking system, the system being characterized in that it comprises: (a) an endothelial precursor cell (EPC) including a cell marker selected from among the group consisting of the Eph (in particular EphB4 or EphB1), and (b) a protein material of structure L-K, which consists of a ligand (L) specific of the marker and is associated or fused with a binding protein (K), the system being capable of providing a proangiogenetic cell material of structure EPC-Eph-L-K. The invention also concerns the cell material as product capable of stimulating angiogenesis, its preparation method and its therapeutic use, in particular with respect to vascular insufficiencies.Type: GrantFiled: July 27, 2006Date of Patent: December 25, 2012Assignees: Institut des Vaisseaux et du Sang, Universite Paris 7-Denis DiderotInventors: Philippe Foubert, Sophie Le Ricousse-Roussanne, Jean-Sebastien Silvestre
-
Publication number: 20120015138Abstract: The use of at least one diazonium salt bearing an initiator function, for forming an undercoat obtained by grafting a graft derived from the diazonium salt and bearing an initiator function at the surface of a conductive or semiconductive material on the undercoat, and for forming on the undercoat a polymeric layer obtained by polymerization, in particular free radical polymerization, in situ of at least one monomer, initiated from the initiator function.Type: ApplicationFiled: September 23, 2011Publication date: January 19, 2012Applicants: ALCHIMEDICS, UNIVERSITE PARIS 7-DENIS DIDEROTInventors: Mohamed Mehdi CHEHIMI, Jean Pinson, Bernadette Charleux, Christophe Bureau, Christopher Tronche, Tarik Matrab, Christian Perruchot, Eva Cabet-Deliry, Maud Save
-
Patent number: 7935807Abstract: The invention relates to a novel polynucleotide exhibiting a promoting transcription activity, polynucleotide-containing vectors and to the use thereof for the transcription of interesting sequences such as the production of non-cap RNA virus. Said invention also relates to host cells preferably of avian origin, containing a polynucleotide or the inventive vector.Type: GrantFiled: February 27, 2004Date of Patent: May 3, 2011Assignees: Institut Pasteur, Centre National de la Recherche Scientifique (SNRS), Universite Paris 7-Denis DiderotInventors: Nadia Naffakh, Pascale Massin, Sylvie Van Der Werf
-
Publication number: 20100221301Abstract: The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprise the steps consisting of a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide and one cross-linking agent b) freezing the aqueous solution of step a) c) sublimating the frozen solution of step b). characterized in that step b) is performed before the cross-linking of the polysaccharide occurs in the solution of step a).Type: ApplicationFiled: October 10, 2008Publication date: September 2, 2010Applicants: UNIVERSITE PARIS 7 - DENIS DIDEROT, RECHERCHE MEDICALE)Inventors: Catherine Le Visage, Didier Letourneur, Frederic Chaubet, Aude Autissier
-
Publication number: 20100221303Abstract: The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprises the steps consisting of: a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide, an amount of a cross-linking agent and an amount of a porogen agent b) transforming the solution into a hydrogel by placing said solution at a temperature from about 4° C. to about 80° C. for a sufficient time to allow the cross-linking of said amount of polysaccharide and c) submerging said hydrogel into an aqueous solution d) washing the porous scaffold obtained at step c).Type: ApplicationFiled: October 10, 2008Publication date: September 2, 2010Applicants: UNIVERSITE PARIS 7 - DENIS DIDEROT, RECHERCHE MEDICALE)Inventors: Catherine Le Visage, Didier Letourneur
-
Publication number: 20100183555Abstract: An in vitro method for determining whether a patient infected with HCV is a responder or non-responder to the treatment with interferon-alpha and ribavirin. More specifically, the method includes a step of determining the expression level of the IFI27, CXCL9 and G1P2 genes in a biological sample.Type: ApplicationFiled: February 4, 2008Publication date: July 22, 2010Applicants: ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS, UNIVERSITE RENE DESCARTES (PARIS V), UNIVERSITE PARIS 7 - DENIS DIDEROTInventors: Michel Vidaud, Ivan Bieche, Tarik Asselah, Patrick Marcellin
-
Patent number: 7751117Abstract: The invention relates to the field of optical parametric oscillators (OPO), especially to an essentially vertical monolithic system (S) for parametric conversion from a pump wave with a pump wavelength, said system comprising at least two resonant cavities (6, 7). Said cavities are coupled by at least one coupling mirror (3), at least one of the cavities comprising an active non-linear medium, and the at least one coupling mirror being arranged in such a way that the parametric frequencies associated with the pump wavelength are located in the stop line of the at least one mirror for an injection direction of the pump wave essentially according to the axis of the system.Type: GrantFiled: June 6, 2006Date of Patent: July 6, 2010Assignees: Centre National de la Recherche Scientifique (corp.), Universite Paris 7-Denis Diderot (university)Inventors: Jerome Tignon, Cristiano Ciuti, Gregor Dasbach, Carole Diederichs
-
Patent number: 7736850Abstract: The invention relates to a novel strain of severe acute respiratory syndrome (SARS)-associated coronavirus, resulting from a sample collected in Hanoi (Vietnam), reference number 031589, nucleic acid molecules originating from the genome of same, proteins and peptides coded by said nucleic acid molecules and, more specifically, protein N and the applications thereof, for example, as diagnostic reagents and/or as a vaccine.Type: GrantFiled: December 2, 2004Date of Patent: June 15, 2010Assignees: Institute Pasteur, Centre National de la Recherche Scientifique, Universite Paris 7Inventors: Sylvie Van Der Werf, Nicolas Escriou, Bernadette Crescenzo-Chaigne, Jean-Claude Manuguerra, Frederick Kunst, Benoît Callendret, Jean-Michel Betton, Valérie Lorin, Sylvie Gerbaud, Ana Maria Burguiere, Saliha Azebi, Pierre Charneau, Frédéric Tangy, Chantal Combredet, Jean-François Delagneau, Monique Martin
-
Patent number: 7679988Abstract: An ultrasound imaging method including an emission step during which an array of transducers is caused to emit at an ultrasound wave focused in a target medium by causing the excitation wave to pass through a reverberant solid object prior to reaching the target medium.Type: GrantFiled: July 23, 2004Date of Patent: March 16, 2010Assignees: Centre National de la Recherche Scientifique -CNRS-, universite Paris 7 - Denis DiderotInventors: Mathias Fink, Gabriel Montaldo, Mickael Tanter
-
Patent number: 7656748Abstract: The invention relates to a method of determining impulse responses from a medium (2) in relation to the transmission of waves between different points (T1-TN). The inventive method consists in: transmitting waves in the medium by generating, at each point j, signals ei(t) each comprising n elementary signals with respective frequencies which are spaced apart in pairs by an interval ?f and which are different from the frequencies of the elementary signals corresponding to the other points; receiving signals rj(t) at points j after the transmission of the aforementioned waves in the medium; and calculating each impulse response hij(t) from a correlation signal between signal ei(t) transmitted at point i and signal rj(t) received at point j.Type: GrantFiled: March 19, 2004Date of Patent: February 2, 2010Assignees: Centre National de la Recherche Scientifique, Universite Paris 7 - Denis DiderotInventors: Matthias Fink, Julien De la Gorgue de Rosny, Claire Julia-Prada, Thomas Folegot
-
Patent number: 7653137Abstract: According to the invention, a wave, corresponding to a signal s(t) may be temporally inverted by application of a first transformation to lower the central frequency thereof to produce a first set of transformed signals Ki(t) then a second set of transformed signals K?i(t) is produced representing the temporal inversion signal s(?t) and a third transformation is applied to said second set to generate the temporally-inverted signal s(?t)Type: GrantFiled: April 11, 2005Date of Patent: January 26, 2010Assignees: Centre National de la Recherche -CNRS-, Universite Paris 7 - Denis DiderotInventors: Mathias Fink, Geoffroy Lerosey, Arnaud Derode, Julien De Rosny, Arnaud Tourin
-
Publication number: 20090275066Abstract: The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.Type: ApplicationFiled: November 13, 2007Publication date: November 5, 2009Applicant: UNIVERSITE PARIS 7 - DENIS DIDEROTInventors: Jean-Luc Popot, Delphine Charvolin, Fabrice Giusti
-
Publication number: 20090097510Abstract: The invention relates to the field of optical parametric oscillators (OPO), especially to an essentially vertical monolithic system (S) for parametric conversion from a pump wave with a pump wavelength, said system comprising at least two resonant cavities (6, 7). Said cavities are coupled by at least one coupling mirror (3), at least one of the cavities comprising an active non-linear medium, and the at least one coupling mirror being arranged in such a way that the parametric frequencies associated with the pump wavelength are located in the stop line of the at least one mirror for an injection direction of the pump wave essentially according to the axis of the system.Type: ApplicationFiled: June 6, 2006Publication date: April 16, 2009Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS, UNIVERSITE PARIS 7 - DENIS DIDEROTInventors: Jerome Tignon, Cristiano Ciuti, Gregor Dasbach, Carole Diederichs
-
Patent number: 7364648Abstract: The invention concerns a metal material with a surface which is modified by bonding an aromatic group, optionally substituted by a functional group, on the surface. In one embodiment, an aromatic group is attached to the surface by electrochemical reduction of a diazonium salt containing the aromatic group. The metal material is brought into contact with a solution of the diazonium salt in a solvent and negatively polarized relative to an anode that is also in contact with the solution. A carbon-metal bond of the covalent type is formed.Type: GrantFiled: May 3, 2005Date of Patent: April 29, 2008Assignee: Universite Paris 7-Denis DiderotInventors: Jean Pinson, Olivier Fagebaume, Fetah Podvorica
-
Publication number: 20070274156Abstract: An ultrasound imaging method including an emission step during which an array of transducers is caused to emit at an ultrasound wave focused in a target medium by causing the excitation wave to pass through a reverberant solid object prior to reaching the target medium.Type: ApplicationFiled: July 23, 2004Publication date: November 29, 2007Applicants: Centre National De La Recherche Scientifque-CNRS, Universite Paris 7 Denis DiderotInventors: Mathias Fink, Gabriel Montaldo, Mickael Tanter
-
Patent number: 7273456Abstract: A method of analyzing an event comprises the steps consisting in: gathering at least one series of measurements of a physical phenomenon associated with the event or likely to be associated therewith; from a predetermined mother wavelet ? and for at least one value of a predetermined parameter a, determining: the partition function Z(q,a) such that: Z ? ( q , a ) = ? b i ? ? ? T ? ? [ s ] ? ( b i , a ) ? q ?where: s is a signal representing variation in the measurements of the series as a function of a variable; T?[s](b,a)=1/a? ?((x?b)/a)s(x)dx where ? is the complex conjugate of the function ?(x) in an orthonormal base; and {(bi,a)}i is the set of local maxima in T as a function of a; the spectrum of the function ?(q) such that: Z(q,a)?a?(q) in the limit a?0+; the spectrum of the function D(h) such that: D ? ( h ) = min q ? ( qh - ? ? ( q ) ) and an index I(a) depending on said spectrum, which index is calculatType: GrantFiled: July 10, 2002Date of Patent: September 25, 2007Assignee: Universite Paris 7 - Denis DiderotInventors: Philippe May, Eric Vicaut, Jean-Marie Servant
-
Publication number: 20070211788Abstract: According to the invention, a wave, corresponding to a signal s(t) may be temporally inverted by application of a first transformation to lower the central frequency thereof to produce a first set of transformed signals Ki(t) then a second set of transformed signals K?i(t) is produced representing the temporal inversion signal s(?t) and a third transformation is applied to said second set to generate the temporally-inverted signal s(?t)Type: ApplicationFiled: April 11, 2005Publication date: September 13, 2007Applicants: CENTRAL NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE PARIS 7-DENIS DIDEROTInventors: Mathias Fink, Geoffory Lerosey, Arnaud Derode, Julien De Rosny, Arnaud Tourin
-
Patent number: 7252004Abstract: An imaging method for observing the propagation of a shear wave simultaneously at a multitude of points in a diffusing viscoelastic medium. The shear wave is caused to be generated by firing at least one focused ultrasound compression wave into the viscoelastic medium by means of an array of transducers, and then emitting at a fast rate and using the same array of transducers, unfocused ultrasound compression waves serving to obtain a succession of images of the medium, and processing the images obtained in this way in deferred time in order to determine the movements of the medium during the propagation of the shear wave.Type: GrantFiled: August 12, 2003Date of Patent: August 7, 2007Assignees: Centre National de la Recherche Scientifique-CNRS, Universite Paris 7Inventors: Mathias A. Fink, Mickael Tanter