Abstract: The invention relates to a water-dispersible derivative of a therapeutic agent having a low water solubility that comprises at least one molecule of said agent covalently bonded to at least one molecule of a hydrocarbon derivative having a squalenic structure or the like. The invention further relates to corresponding nanoparticles.
Type:
Grant
Filed:
November 27, 2008
Date of Patent:
February 24, 2015
Assignees:
Centre Nationale de Recherche Scientifique, Universite Paris SU XI
Inventors:
Patrick Couvreur, Harivardhan Reddy Lakkireddy, Franco Dosio, Barbara Stella, Luigi Cattel