Abstract: The present invention relates to methods and pharmaceutical compositions for treating cancer. More specifically, the invention relates to a polypeptide isolated from Brevibacterium aurantiacum that shows methionine gamma-lyase and homocysteinase activities. The present invention also relates to the use of such a polypeptide for the treatment of cancer.

Abstract: The present invention relates to methods and pharmaceutical compositions for treating cancer. More specifically, the invention relates to a polypeptide isolated from Brevibacterium aurantiacum that shows methionine gamma-lyase and homocysteinase activities. The present invention also relates to the use of such a polypeptide for the treatment of cancer.

Abstract: Pyridocarbazole-type compounds of formula (I): are provided as a medicament, and more particularly for application in anticancer chemotherapy. Also provided is a pharmaceutical composition with the compound and methods for preventing and/or treating neurodegenerative-type pathologies, such as Alzheimer's disease and schizophrenia, parasitoses, such as malaria, or glaucomas.

Abstract: Substrate, in particular in silicon carbide, covered by a thin film of stoichiometric silicon nitride, for the manufacture of electronic components and method for obtaining said film. To obtain the film on the substrate (1) in the presence of at least one nitrogen gas, the substrate is covered with a film (2) of a material that is permeable to said gas and the film of silicon nitride is capable of forming at the interface between the substrate and the film of the material. The invention applies for example to microelectronics.

Abstract: An antenna, permitting the configuration of at least one radioelectric wave beam of at least one fixed wavelength, of the type including at least one transmitting element, preferably of the passive type, arranged in a set of essentially parallel, wave-reflecting wires or bars, made from a photonic band gap (BIP) material and forming a given structure. The given structure includes faults for shaping the at least one beam in a direction as a function of the position and/or the configuration of the faults. The wires or bars and the faults are arranged on a set of N curves which are closed and concentric on a plane, N being greater than or equal to 1 and the transmitting element is arranged within the innermost curve. The curves are preferably circular and the wires/bars can be controlled to pass from a wave-conducting/reflecting state to a transparent state.

Abstract: Silicon layer highly sensitive to oxygen and method for obtaining said layer. This layer (2), formed on a substrate (4) for example of SiC, has a 3'2 structure. To obtain it, it is possible to substantially uniformly deposit silicon on a surface of the substrate. The invention can be applied for example to microelectronics.

Abstract: Process for the stabilization of mercury metal by reaction of the mercury metal with sulphur in the solid state, in which the mercury and the sulphur are brought into contact, at an Hg/S molar ratio of 1/1 to 1/3, in a reactor integral with a hollow pipe in fluid communication with the interior space of the said reactor, the said hollow pipe comprising a first end connected to the wall of the said reactor and a second end distant from the said reactor; the said hollow pipe and the said reactor being hermetically sealed, the said hollow pipe being provided with rotating means external to the said pipe and to the said reactor for rotating the said reactor and the said pipe around the axis of the said pipe, and the said hollow pipe being provided, at its end distant from the reactor, with means for introducing the sulphur and the mercury inside the reactor and discharging the reaction products.

Abstract: Process for the stabilization of mercury metal by reaction of the mercury metal with sulphur in the solid state, in which the mercury and the sulphur are brought into contact, at an Hg/S molar ratio of 1/1 to 1/3, in a reactor integral with a hollow pipe in fluid communication with the interior space of the said reactor, the said hollow pipe comprising a first end connected to the wall of the said reactor and a second end distant from the said reactor; the said hollow pipe and the said reactor being hermetically sealed, the said hollow pipe being provided with rotating means external to the said pipe and to the said reactor for rotating the said reactor and the said pipe around the axis of the said pipe, and the said hollow pipe being provided, at its end distant from the reactor, with means for introducing the sulphur and the mercury inside the reactor and discharging the reaction products.

Abstract: The invention relates to derivatives corresponding to formula I: in which X is an alkyl-(CH2)n— chain with n=0, 1 or 2, or O or N, Z is an aromatic which may contain heteroatoms chosen from O, N or S, as substitutions for the carbon atoms constituting said aromatic ring, this ring being substituted or otherwise with Rb, Rb represents 1 to 3 substituents chosen from —OH, —OR, —COOH, —COOR, —COH, —COR, —NH2, —NH(R), —NH(R,R?), —SH, —SR and CN, Ra is H or —(CH2)n?—Y, with n?=0, 1, 2 or 3 and Y and —CH3, —COOH, —COOR, —CN, —OH, —OR, SR, or an aryl group optionally substituted with Rb, R and R? represent a linear or branched alkyl chain of 1 to 4 C, and their pharmaceutically acceptable salts. Application as active ingredient of medicaments inhibiting retrovirus integrases.

Abstract: Calculator based resolution method and device for an optimization problem of the physical real world, the problem being modeled with constrained discrete variables, the variables having a referenced set of possible states. The method comprising, a survey propagation step and a survey induced decimation step to provide a simplified problem, until all variables are either assigned or are unpolarized.

Abstract: Calculator based resolution method and device for an optimization problem of the physical real world, the problem being modeled with constrained discrete variables, the variables having a referenced set of possible states. The method comprising, a survey propagation step and a survey induced decimation step to provide a simplified problem, until all variables are either assigned or are unpolarized.

Abstract: The present invention relates to biodegradable microcapsules based on serum albumin, the preparation thereof and the application thereof to the release of drugs in situ.A feature of the microcapsules according to the present invention is that their wall consists of serum albumin, a portion of which is crosslinked by interfacial polymerization with the aid of an acylating bifunctional reagent, and the other, non-crosslinked portion of which is denatured by means of an alcohol.