Patents Assigned to Universite Toulouse III - Paul Sabatier
-
Publication number: 20240101618Abstract: The present invention relates to an isolated peptide consisting of a sequence of 3 to 39 amino acids derived from the amino acid sequence SEQ ID NO: 1, said peptide having a sequence of amino acids selected from the group consisting of: a) sequences of 3 to 39 amino acids comprising at least the residues 6 to 8 of SEQ ID NO: 1, and b) sequences of 3 to 39 amino acids having at least 70% identity with said sequence in a).Type: ApplicationFiled: August 3, 2023Publication date: March 28, 2024Applicants: INSTITUT NATIONAL UNIVERSITAIRE JEAN-FRANCOIS CHAMPOLLION, UNIVERSITE TOULOUSE III - PAUL SABATIER, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE DE ROUEN-NORMANDIEInventors: Khaddouj Benmoussa, Elsa Bonnafe, Agnès Coste, Jérôme Leprince, Bernard Pipy, Michel Treilhou
-
Publication number: 20240075097Abstract: Compositions containing micropeptides capable of modulating the accumulation of miRs involved in certain pathologies, and the use of these micropeptides for treating the certain pathologies. Also, methods of identifying these micropeptides modulating the accumulation of miRs involved in pathologies. Further, nuclei acids encoding those micropeptides that modulate the accumulation of miRs involved in pathologies.Type: ApplicationFiled: December 27, 2022Publication date: March 7, 2024Applicants: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), ETABLISSEMENT FRANÇAIS DU SANGInventors: Jean-Philippe COMBIER, Anne PREL, Frédéric DESCHASEAUX
-
Publication number: 20230334301Abstract: The invention relates to a method for quantizing a deep neural network including several layers, previously trained during a training phase determining for each layer a set of weights. The method includes a phase of quantizing the deep neural network including determining a disruption limit value of at least one weight of the weight set of the layer, beyond which the output of the deep neural network is erroneous, determining, for a target inference precision of the neural network, and from the disruption limit value, an adjustment limit value of at least one weight of the set of weights, and decreasing an arithmetic precision of at least one weight of the set of weights as a function of the adjustment limit value. The invention also relates to a computer program, a device implementing such a method, and a deep neural network obtained by such a method.Type: ApplicationFiled: April 13, 2023Publication date: October 19, 2023Applicants: BULL SAS, INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, UNIVERSITE TOULOUSE III - PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Stéphane PRALET, Théo BEUZEVILLE, Alfredo BUTTARI, Serge GRATTON
-
Publication number: 20230279355Abstract: The method for the in vitro or ex vivo amplification of stem cells of brown or beige adipocytes includes: extracting (i) a stromal vascular fraction from human adipose tissue including endothelial cells of the vascular network of human adipose tissue and stem cells of brown or beige human adipose tissue and (ii) an extracellular matrix of the human adipose tissue, the extracellular matrix including endothelial cells of the vascular network of human adipose tissue, stem cells of brown or beige human adipose tissue and collagen; mixing the stromal vascular fraction and the extracellular matrix; and culturing the mixture obtained, in suspension, in a culture medium.Type: ApplicationFiled: July 15, 2021Publication date: September 7, 2023Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CHU DE NICE, ETABLISSEMENT FRANCAIS DU SANG, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE COTE D'AZUR, UNIVERSITE TOULOUSE III - PAUL SABATIERInventors: Christian, Jean, Lucien Dani, Vincent Dani, Louis Casteilla, Alain, Pierre, Louis Doglio, Philippe Letertre
-
Publication number: 20230151147Abstract: A process for preparing preferably degradable copolymers by free radical ring-opening polymerization using thionolactone monomers or thionocarbonate monomers, in the presence of a radical polymerization initiator. Also, the copolymers, which include thioester or thiocarbonate bonds, that are obtained by carrying out the process including the free radical ring-opening polymerization using thionolactone monomers or thionocarbonate monomers.Type: ApplicationFiled: April 8, 2021Publication date: May 18, 2023Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE TOULOUSE III - PAUL SABATIERInventors: Simon HARRISSON, Mathias DESTARAC
-
Patent number: 11607443Abstract: Compositions containing micropeptides capable of modulating the accumulation of miRs involved in certain pathologies, and the use of these micropeptides for treating the certain pathologies. Also, methods of identifying these micropeptides modulating the accumulation of miRs involved in pathologies. Further, nuclei acids encoding those micropeptides that modulate the accumulation of miRs involved in pathologies.Type: GrantFiled: December 22, 2017Date of Patent: March 21, 2023Assignees: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), ETABLISSEMENT FRANçAIS DU SANGInventors: Jean-Philippe Combier, Anne Prel, Frédéric Deschaseaux
-
Publication number: 20210212281Abstract: Micropeptides (miPEPs), or peptides coded by microRNAs, for promoting nodulation between a plant and a bacterium, as well as their use in this manner.Type: ApplicationFiled: March 25, 2021Publication date: July 15, 2021Applicants: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jean-Philippe COMBIER, Olivier ANDRE
-
Patent number: 10959393Abstract: Micropeptides (miPEPs), or peptides coded by microRNAs, for promoting nodulation between a plant and a bacterium, as well as their use in this manner.Type: GrantFiled: March 24, 2016Date of Patent: March 30, 2021Assignees: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jean-Philippe Combier, Olivier Andre
-
Publication number: 20200079912Abstract: The invention relates to a block copolymer film nanostructured in nanodomains, said copolymer comprising at least one first biodegradable block and a second block of a different chemical nature than the first block, said block copolymer being characterized in that the first biodegradable block is amorphous and in that the second block is derived from an oligomer or a polymer bearing a hydroxyl function on at least one end and acting as macro-initiator of the polymerization of the first block.Type: ApplicationFiled: December 13, 2017Publication date: March 12, 2020Applicants: Arkema France, Centre National de la Recherche Scientifique, Université Toulouse III - Paul SabatierInventors: Christophe Navarro, Didier Bourissou, Blanca Martin-Vaca, Franck Kayser
-
Patent number: 10563214Abstract: The present invention relates to the use of micropeptides (peptides encoded by microRNAs or “miPEPs”) for promoting plant growth.Type: GrantFiled: June 3, 2015Date of Patent: February 18, 2020Assignees: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jean-Philippe Combier, Dominique Laures-Sergues, Guillaume Becard
-
Publication number: 20200000878Abstract: Compositions containing micropeptides capable of modulating the accumulation of miRs involved in certain pathologies, and the use of these micropeptides for treating the certain pathologies. Also, methods of identifying these micropeptides modulating the accumulation of miRs involved in pathologies. Further, nuclei acids encoding those micropeptides that modulate the accumulation of miRs involved in pathologies.Type: ApplicationFiled: December 22, 2017Publication date: January 2, 2020Applicants: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), ETABLISSEMENT FRANÇAIS DU SANGInventors: Jean-Philippe COMBIER, Anne PREL, Frédéric DESCHASEAUX
-
Patent number: 10501798Abstract: Providing Nuclear factor (erythroid-derived 2)-like 2 (NRF2)-activated genes products, e.g. SOD1 and CAT, in their use in the prognosis of an OPA1 gene- or OPA1 gene product-deficit-induced disease, or related complications, e.g. optic atrophy and optic neuropathy, in a biological sample selected from fibroblasts, epithelial cells, blood samples or a mixture thereof, of a patient affected or suspected to be affected by the disease.Type: GrantFiled: March 27, 2015Date of Patent: December 10, 2019Assignees: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Noelie Davezac, Pascale Belenguer, Aurelie Millet
-
Publication number: 20190330286Abstract: Embodiments of the present disclosure relate to an isolated peptide consisting of a sequence of 3 to 39 amino acids derived from the amino acid sequence SEQ ID NO: 1, said peptide having a sequence of amino acids selected from the group consisting of: a) sequences of 3 to 39 amino acids comprising at least the residues 6 to 8 of SEQ ID NO: 1, and b) sequences of 3 to 39 amino acids having at least 70% identity with said sequence in a).Type: ApplicationFiled: January 12, 2018Publication date: October 31, 2019Applicants: INSTITUT NATIONAL UNIVERSITAIRE JEAN-FRANCOIS CHAMPOLLION, UNIVERSITE TOULOUSE III - PAUL SABATIER, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE DE ROUEN-NORMANDIEInventors: Khaddouj Benmoussa, Elsa Bonnafe, Agnès Coste, Jérôme Leprince, Bernard Pipy, Michel Treilhou
-
Publication number: 20190187559Abstract: Provided is a block copolymer film nanostructured in nanodomains, where the copolymer includes at least one first biodegradable block of polyester type and a second block of a different chemical nature than the first block. The first block of polyester type is polybutyrolactone (PBL) and the second block is derived from an oligomer or from a polymer bearing a hydroxyl function on at least one end and acting as macro-initiator of the polymerization of ?-butyrolactone (?-BL) to give polybutyrolactone (PBL).Type: ApplicationFiled: June 22, 2017Publication date: June 20, 2019Applicants: Arkema France, Centre National De La Recherche Scientifique - CNR, Universite Toulouse III - Paul SabatierInventors: Christophe Navarro, Didier Bourissou, Blanca Martin-Vaca, Aline Couffin, Franck Kayser
-
Publication number: 20180049726Abstract: The invention relates to a device for capture of cellular biomarkers circulating in an animal or human biological flow, characterised in that it is suitable for use in vivo and in that it comprises a means of filtration intended to retain the said cellular biomarkers, the said means of filtration comprising at least one through-aperture the dimensions of which are suitable for retaining the said cellular biomarkers and being integral with a support, the support taking the form of a hollow component.Type: ApplicationFiled: February 2, 2016Publication date: February 22, 2018Applicants: Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire de Toulouse, Universite Toulouse III - Paul SabatierInventors: Aline Cerf, Sylvain Sanson, Hélène Cayron, Alejandro Kayum Jimenez, Christophe Vieu, Bernard Malavaud