Patents Assigned to Universite Toulouse III - Paul Sabatier
  • Publication number: 20240101618
    Abstract: The present invention relates to an isolated peptide consisting of a sequence of 3 to 39 amino acids derived from the amino acid sequence SEQ ID NO: 1, said peptide having a sequence of amino acids selected from the group consisting of: a) sequences of 3 to 39 amino acids comprising at least the residues 6 to 8 of SEQ ID NO: 1, and b) sequences of 3 to 39 amino acids having at least 70% identity with said sequence in a).
    Type: Application
    Filed: August 3, 2023
    Publication date: March 28, 2024
    Applicants: INSTITUT NATIONAL UNIVERSITAIRE JEAN-FRANCOIS CHAMPOLLION, UNIVERSITE TOULOUSE III - PAUL SABATIER, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE DE ROUEN-NORMANDIE
    Inventors: Khaddouj Benmoussa, Elsa Bonnafe, Agnès Coste, Jérôme Leprince, Bernard Pipy, Michel Treilhou
  • Publication number: 20240075097
    Abstract: Compositions containing micropeptides capable of modulating the accumulation of miRs involved in certain pathologies, and the use of these micropeptides for treating the certain pathologies. Also, methods of identifying these micropeptides modulating the accumulation of miRs involved in pathologies. Further, nuclei acids encoding those micropeptides that modulate the accumulation of miRs involved in pathologies.
    Type: Application
    Filed: December 27, 2022
    Publication date: March 7, 2024
    Applicants: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), ETABLISSEMENT FRANÇAIS DU SANG
    Inventors: Jean-Philippe COMBIER, Anne PREL, Frédéric DESCHASEAUX
  • Publication number: 20230334301
    Abstract: The invention relates to a method for quantizing a deep neural network including several layers, previously trained during a training phase determining for each layer a set of weights. The method includes a phase of quantizing the deep neural network including determining a disruption limit value of at least one weight of the weight set of the layer, beyond which the output of the deep neural network is erroneous, determining, for a target inference precision of the neural network, and from the disruption limit value, an adjustment limit value of at least one weight of the set of weights, and decreasing an arithmetic precision of at least one weight of the set of weights as a function of the adjustment limit value. The invention also relates to a computer program, a device implementing such a method, and a deep neural network obtained by such a method.
    Type: Application
    Filed: April 13, 2023
    Publication date: October 19, 2023
    Applicants: BULL SAS, INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, UNIVERSITE TOULOUSE III - PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stéphane PRALET, Théo BEUZEVILLE, Alfredo BUTTARI, Serge GRATTON
  • Publication number: 20230279355
    Abstract: The method for the in vitro or ex vivo amplification of stem cells of brown or beige adipocytes includes: extracting (i) a stromal vascular fraction from human adipose tissue including endothelial cells of the vascular network of human adipose tissue and stem cells of brown or beige human adipose tissue and (ii) an extracellular matrix of the human adipose tissue, the extracellular matrix including endothelial cells of the vascular network of human adipose tissue, stem cells of brown or beige human adipose tissue and collagen; mixing the stromal vascular fraction and the extracellular matrix; and culturing the mixture obtained, in suspension, in a culture medium.
    Type: Application
    Filed: July 15, 2021
    Publication date: September 7, 2023
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CHU DE NICE, ETABLISSEMENT FRANCAIS DU SANG, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE COTE D'AZUR, UNIVERSITE TOULOUSE III - PAUL SABATIER
    Inventors: Christian, Jean, Lucien Dani, Vincent Dani, Louis Casteilla, Alain, Pierre, Louis Doglio, Philippe Letertre
  • Publication number: 20230151147
    Abstract: A process for preparing preferably degradable copolymers by free radical ring-opening polymerization using thionolactone monomers or thionocarbonate monomers, in the presence of a radical polymerization initiator. Also, the copolymers, which include thioester or thiocarbonate bonds, that are obtained by carrying out the process including the free radical ring-opening polymerization using thionolactone monomers or thionocarbonate monomers.
    Type: Application
    Filed: April 8, 2021
    Publication date: May 18, 2023
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE TOULOUSE III - PAUL SABATIER
    Inventors: Simon HARRISSON, Mathias DESTARAC
  • Patent number: 11607443
    Abstract: Compositions containing micropeptides capable of modulating the accumulation of miRs involved in certain pathologies, and the use of these micropeptides for treating the certain pathologies. Also, methods of identifying these micropeptides modulating the accumulation of miRs involved in pathologies. Further, nuclei acids encoding those micropeptides that modulate the accumulation of miRs involved in pathologies.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: March 21, 2023
    Assignees: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), ETABLISSEMENT FRANçAIS DU SANG
    Inventors: Jean-Philippe Combier, Anne Prel, Frédéric Deschaseaux
  • Publication number: 20210212281
    Abstract: Micropeptides (miPEPs), or peptides coded by microRNAs, for promoting nodulation between a plant and a bacterium, as well as their use in this manner.
    Type: Application
    Filed: March 25, 2021
    Publication date: July 15, 2021
    Applicants: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Philippe COMBIER, Olivier ANDRE
  • Patent number: 10959393
    Abstract: Micropeptides (miPEPs), or peptides coded by microRNAs, for promoting nodulation between a plant and a bacterium, as well as their use in this manner.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: March 30, 2021
    Assignees: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Philippe Combier, Olivier Andre
  • Publication number: 20200079912
    Abstract: The invention relates to a block copolymer film nanostructured in nanodomains, said copolymer comprising at least one first biodegradable block and a second block of a different chemical nature than the first block, said block copolymer being characterized in that the first biodegradable block is amorphous and in that the second block is derived from an oligomer or a polymer bearing a hydroxyl function on at least one end and acting as macro-initiator of the polymerization of the first block.
    Type: Application
    Filed: December 13, 2017
    Publication date: March 12, 2020
    Applicants: Arkema France, Centre National de la Recherche Scientifique, Université Toulouse III - Paul Sabatier
    Inventors: Christophe Navarro, Didier Bourissou, Blanca Martin-Vaca, Franck Kayser
  • Patent number: 10563214
    Abstract: The present invention relates to the use of micropeptides (peptides encoded by microRNAs or “miPEPs”) for promoting plant growth.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: February 18, 2020
    Assignees: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Philippe Combier, Dominique Laures-Sergues, Guillaume Becard
  • Publication number: 20200000878
    Abstract: Compositions containing micropeptides capable of modulating the accumulation of miRs involved in certain pathologies, and the use of these micropeptides for treating the certain pathologies. Also, methods of identifying these micropeptides modulating the accumulation of miRs involved in pathologies. Further, nuclei acids encoding those micropeptides that modulate the accumulation of miRs involved in pathologies.
    Type: Application
    Filed: December 22, 2017
    Publication date: January 2, 2020
    Applicants: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), ETABLISSEMENT FRANÇAIS DU SANG
    Inventors: Jean-Philippe COMBIER, Anne PREL, Frédéric DESCHASEAUX
  • Patent number: 10501798
    Abstract: Providing Nuclear factor (erythroid-derived 2)-like 2 (NRF2)-activated genes products, e.g. SOD1 and CAT, in their use in the prognosis of an OPA1 gene- or OPA1 gene product-deficit-induced disease, or related complications, e.g. optic atrophy and optic neuropathy, in a biological sample selected from fibroblasts, epithelial cells, blood samples or a mixture thereof, of a patient affected or suspected to be affected by the disease.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: December 10, 2019
    Assignees: UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Noelie Davezac, Pascale Belenguer, Aurelie Millet
  • Publication number: 20190330286
    Abstract: Embodiments of the present disclosure relate to an isolated peptide consisting of a sequence of 3 to 39 amino acids derived from the amino acid sequence SEQ ID NO: 1, said peptide having a sequence of amino acids selected from the group consisting of: a) sequences of 3 to 39 amino acids comprising at least the residues 6 to 8 of SEQ ID NO: 1, and b) sequences of 3 to 39 amino acids having at least 70% identity with said sequence in a).
    Type: Application
    Filed: January 12, 2018
    Publication date: October 31, 2019
    Applicants: INSTITUT NATIONAL UNIVERSITAIRE JEAN-FRANCOIS CHAMPOLLION, UNIVERSITE TOULOUSE III - PAUL SABATIER, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE DE ROUEN-NORMANDIE
    Inventors: Khaddouj Benmoussa, Elsa Bonnafe, Agnès Coste, Jérôme Leprince, Bernard Pipy, Michel Treilhou
  • Publication number: 20190187559
    Abstract: Provided is a block copolymer film nanostructured in nanodomains, where the copolymer includes at least one first biodegradable block of polyester type and a second block of a different chemical nature than the first block. The first block of polyester type is polybutyrolactone (PBL) and the second block is derived from an oligomer or from a polymer bearing a hydroxyl function on at least one end and acting as macro-initiator of the polymerization of ?-butyrolactone (?-BL) to give polybutyrolactone (PBL).
    Type: Application
    Filed: June 22, 2017
    Publication date: June 20, 2019
    Applicants: Arkema France, Centre National De La Recherche Scientifique - CNR, Universite Toulouse III - Paul Sabatier
    Inventors: Christophe Navarro, Didier Bourissou, Blanca Martin-Vaca, Aline Couffin, Franck Kayser
  • Publication number: 20180049726
    Abstract: The invention relates to a device for capture of cellular biomarkers circulating in an animal or human biological flow, characterised in that it is suitable for use in vivo and in that it comprises a means of filtration intended to retain the said cellular biomarkers, the said means of filtration comprising at least one through-aperture the dimensions of which are suitable for retaining the said cellular biomarkers and being integral with a support, the support taking the form of a hollow component.
    Type: Application
    Filed: February 2, 2016
    Publication date: February 22, 2018
    Applicants: Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire de Toulouse, Universite Toulouse III - Paul Sabatier
    Inventors: Aline Cerf, Sylvain Sanson, Hélène Cayron, Alejandro Kayum Jimenez, Christophe Vieu, Bernard Malavaud