Abstract: A key holder includes a ferrule, a multimode light guide at least partly embedded inside the ferrule, an optical key which has a light scattering material, and a mechanical mount which mounts each of the ferrule, the multimode light guide, and the optical key. The multimode light guide has a front facet and a back facet which are arranged at opposite ends. The back facet of the multimode light guide contacts the optical key. Light can enter into the multimode light guide via the front facet, propagate through the multimode light guide, be scattered by the optical key, and propagate back through the multimode light guide and exit via the front facet. The mechanical mount is detachably connected to a mechanical mount terminator. The front facet of the multimode light guide is oriented in a direction of the mechanical mount terminator.

Abstract: A method for determining a scaled respiratory flow rate and volume during respiration of a patient includes a) successively determining a plurality of values for a difference between a pressure in at least a first location in an upper respiratory tract of the patient and a reference pressure, b) deriving the scaled respiratory flow rate from the plurality of values for the pressure difference by using a first relationship, c) deriving the scaled respiratory volume from the plurality of values for the pressure difference by using a second relationship, and d) displaying the scaled respiratory flow rate derived in step b) and the scaled respiratory volume derived in step c) or a further variable derived from the scaled respiratory flow rate and volume in a graphical representation. Step a) is performed during tidal breathing of the patient. A system for performing the aforementioned method.

Abstract: Disclosed are compositions for use in the simultaneous removal of endotoxins from dialysate and uremic solutes from blood during the treatment of patients. The treatment is selected from the group consisting of hemodialysis and hemodiafiltration. The compositions comprise sorbent particles embedded in a membrane comprising a polymer and a hydrophilic additive.

Abstract: A method for monitoring a system for injecting heated air into a patient. The system includes a source of air, a device for heating the air, a cannula for insertion into nostrils of the patient, a first conduit interconnecting the source and the device, and a second conduit interconnecting the device and the cannula. The method includes deriving pressure in the cannula from pressure of the air between the source and the cannula. The method includes measuring a pressure of the air at between the source and the cannula, determining a flow rate of the air in the system, deriving a first function representative of a respiratory flow rate of the patient from the measured pressure and the system air flow rate, deriving a second function representative of a respiratory volume of the patient from the measured pressure and the system air flow rate, and graphically displaying the functions.

Abstract: A method of printing a cellular solid by direct bubble writing comprises introducing an ink formulation comprising a polymerizable monomer and a gas into a nozzle, which includes a core flow channel radially surrounded by an outer flow channel. The ink formulation is directed into the outer flow channel and the gas is directed into the core flow channel. The ink formulation and the gas are ejected out of the nozzle as a stream of bubbles, where each bubble includes a core comprising the gas and a liquid shell overlying the core that comprises the ink formulation. After ejection, the polymerizable monomer is polymerized to form a solid polymeric shell from the liquid shell, and the bubbles are deposited on a substrate moving relative to the nozzle. Thus, a polymeric cellular solid having a predetermined geometry is printed.

Abstract: The present disclosure relates to a conductivity measuring system of a fluid including a solvent and an ionic solute, comprising: —a holder comprising an isolated holder wall defining a fluid channel for holding fluid, wherein the holder is shaped to allow an electrical current induced in the fluid to form a current loop; —an excitation device configured to excite an electric field inside a first part of the fluid channel, the excitation device comprising an electrical signal generator configured to generate an alternating current signal and a conducting slab; —a sensing device arranged at a position remote from the first part of the fluid channel and configured to sense a voltage signal (V) resulting from the changing magnetic field resulting from the current generated inside the fluid by the excitation device.

Abstract: The invention relates to a method and apparatus for detecting superparamagnetic material. The method comprises applying, by an excitation coil, a magnetic field during a first period to an object to modulate a magnetization of the superparamagnetic material, the magnetic field comprising a first component with a first frequency; positioning a sensing device at a first position from the excitation coil receiving a first signal by a first detection sub-coil in the sensing device and a second signal by a second detection-sub-coil in the sensing device; determining a sensor signal from the first signal and the second signal; determining a detection signal based on the sensor signal; determining a parameter indicating an amount of superparamagnetic material by dividing the detection signal by the first signal, and repeating steps to at at least one different position in order to determine a location where the parameter has a maximal value.

Abstract: A method of printing a cellular solid (120) by direct bubble writing comprises introducing an ink formulation (102) comprising a polymerizable monomer and a gas (104) into a nozzle (106), which includes a core flow channel (108) radially surrounded by an outer flow channel (110). The ink formulation is directed into the outer flow channel (110) and the gas is directed into the core flow channel (108). The ink formulation (102) and the gas (104) are ejected out of the nozzle (106) as a stream of bubbles (112), where each bubble includes a core (114) comprising the gas and a liquid shell (116) overlying the core that comprises the ink formulation. After ejection, the polymerizable monomer is polymerized to form a solid polymeric shell (118) from the liquid shell (116), and the bubbles are deposited on a substrate (122) moving relative to the nozzle (106). Thus, a polymeric cellular solid (120) having a predetermined geometry is printed.

Abstract: The disclosure relates to integrin binding peptides, pharmaceutical compositions comprising the peptides and to uses thereof as therapeutic, diagnostic, imaging and targeting agents.

Abstract: The invention relates to a method of fabricating a micro machined channel, comprising the steps of providing a substrate of a first material and having a buried layer of a different material therein, and forming at least two trenches in said substrate by removing at least part of said substrate. Said trenches are provided at a distance from each other and at least partly extend substantially parallel to each other, as well as towards said buried layer. The method comprises the step of forming at least two filled trenches by providing a second material different from said first material and filling said at least two trenches with at least said second material; forming an elongated cavity in between said filled trenches by removing at least part of said substrate extending between said filled trenches; and forming an enclosed channel by providing a layer of material in said cavity and enclosing said cavity.

Abstract: A method for a PUK authenticated communication includes creating an optical challenge in a time-frequency domain, providing the optical challenge to a tPUK which includes a spatial input channel and a plurality of spatial output channels, and detecting in which of the plurality of spatial output channels a short temporally focused pulse is created. The tPUK provides a complex challenge-response behavior in the time-frequency domain. The optical challenge is created so that the tPUK creates the response having a short temporally focused pulse in only one of the plurality of spatial output channels of the tPUK.

Abstract: The present invention relates to a method for preparing a membrane comprising sorbent particles that bind urea. The invention also relates to the sorbent-comprising membranes per se, and to methods of using the membranes. The membranes are useful for undergoing subsequent reactions with small molecules such as urea, for instance to remove urea from a solution.

Abstract: Aspects of the present disclosure describe improved supercontinuum generation based upon alternating optical dispersion along a waveguide length that advantageously generates much more spectral bandwidth than possible with conventional, prior art techniques without losing coherence as well as supporting a larger range of pulse energies (i.e., for lower than conventionally allowed pulse energies or high pulse energies).

Abstract: The invention provides a construct (1) comprising a number N of material types (100, 110, . . . ), wherein N is at least 2, wherein at least two of the material types (100, 110, . . . ) comprise granular material (101) comprising particles (10), wherein the granular material (101) at least defines an exterior surface (6) of the construct (1), wherein the construct (1) is self-supporting, and wherein the construct (1) is (i) self-healing or is (ii) configured for being self-healing by changing a liquid (15) content of the construct (1); wherein the different material types (100, 110, . . . ) mutually differ in at least one characteristic (19) selected from the group consisting of a physical characteristic and a chemical characteristic.

Abstract: The invention is in the field of methods for preparing polymer films, and of such polymer films. The method involves phase separation and requires only aqueous solution, eliminating the need for organic solvents. The aqueous phase separation involves contacting a polymer solution comprising a trigger-responsive polymer with an aqueous coagulation solution in which the trigger-responsive polymer is not soluble.

Abstract: A jet injection system (10) comprising (i) a microfluidic device (100) for jet ejection and (ii) a laser-based heating system (200), wherein: —the microfluidic device (100) comprises a hosting chamber (110) defined by a chamber wall (120), the hosting chamber (110) having a chamber height he selected from the range of 5-400 ?m, a chamber width we selected from the range of 2hc-10hc, and a chamber length lc defined by a first chamber end (111) and a second chamber end (112), wherein the second chamber end (112) comprises a first chamber opening (131) for jet ejection from the hosting chamber (110), and wherein the hosting chamber (110) is configured to host a liquid (50); —the laser-based heating system (200) is configured to provide laser radiation (201) to one or more of the chamber wall (120) and a liquid (50) in the hosting chamber (110).

Abstract: The invention provides a sensor (100) for sensing a predetermined particle (10) in a fluid (11), wherein the sensor (100) comprises (i) an electrode (110) and (ii) an recognition element (112), wherein the electrode (110) comprises an electrode face (111) configured accessible to the fluid (11), to the predetermined particle (10) in the fluid (11), and to a redox mediator (12) in the fluid (11); and wherein the recognition element (112) is configured to at least temporarily selectively bind with the predetermined particle (10), thereby limiting access of the redox mediator (12) to the electrode face (111) during the binding of the predetermined particle with the recognition element (112).

Abstract: The invention relates to a method for creating a porous film through aqueous phase separation, the method comprising: i) providing an aqueous solution comprising a responsive copolymer, and optionally a charged polymer, wherein at least one of the monomers in the responsive copolymer is a responsive monomer; ii) forming the aqueous solution into a thin layer and contacting the thin layer of aqueous solution with an aqueous coagulation solution in which the responsive copolymer is not soluble, or contacting the thin layer of aqueous solution with an aqueous coagulation solution in which a complex comprising the responsive copolymer and the charged polymer is not soluble; and iii) allowing solvent exchange between the aqueous solution and the aqueous coagulation solution to produce a porous film. The invention further relates to porous films or membranes thus obtained.

Abstract: A method of printing a cellular solid (120) by direct bubble writing comprises introducing an ink formulation (102) comprising a polymerizable monomer and a gas (104) into a nozzle (106), which includes a core flow channel (108) radially surrounded by an outer flow channel (110). The ink formulation is directed into the outer flow channel (110) and the gas is directed into the core channel (108). The ink formulation (102) and the gas (104) are ejected out of the nozzle (106) as a stream of bubbles (112), where each bubble includes a core (114) comprising the gas and a liquid shell (116) overlying the core that comprises the ink formulation. After ejection, the polymerizable monomer is polymerized to form a solid polymeric shell (118) from the liquid shell (116), and the bubbles are deposited on a substrate (122) moving relative to the nozzle (106). Thus, a polymeric cellular solid (120) having a predetermined geometry is printed.

Abstract: The invention relates to a channel comprising device (1) comprising a channel (10) with a channel wall (15), a channel inlet (11) and a channel outlet (12), wherein the channel wall comprises a polymer (150),wherein the polymer (150) comprises an epoxy-based polymer. The invention further relates to a system (1000) comprising a Coriolis-type flow measuring device(50) comprising the channel comprising device (1) according to the invention and an actuation system (450) configured to let at least part of the channel (10) vibrate thereby causing temporary displacements. The invention, further relates a method for measuring a property of a fluid, wherein the property of the fluid is a property selected form the group consisting of a mass flow rate of the fluid and a density of the fluid.