Patents Assigned to Universiti Malaya
  • Patent number: 11705020
    Abstract: A method of manufacturing a three dimensional bio-model from medical image data is described. The method comprises: identifying a skin layer in the medical image data; determining a thickness of the skin layer; generating three dimensional model data from the medical image data, the three dimensional model data comprising an indication of a synthetic skin layer, the synthetic skin layer comprising a surface layer and a backing layer, wherein a combined thickness of the surface layer and the backing layer is determined from the thickness of the skin layer; and three dimensional printing the three dimensional model data to provide a three dimensional bio-model.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: July 18, 2023
    Assignee: UNIVERSITI MALAYA
    Inventors: Vickneswaran A/L Mathaneswaran, Zainal Ariff Bin Abdul Rahman, Yuwaraj Kumar A/L Balakrishnan, Su Tung Tan
  • Patent number: 11521519
    Abstract: A cranial bio-model including a skull layer and a dura layer and method of manufacturing a cranial bio-model. A three dimensional bio-model for simulating a simulated cranial surgical procedure, the bio-model comprises a synthetic skull layer, a synthetic dura layer under the synthetic skull layer, and a spacer layer between the synthetic skull layer and the synthetic dura layer. The bio-model may be manufactured based on medical image data using three-dimensional printing.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: December 6, 2022
    Assignee: Universiti Malaya
    Inventors: Vickneswaran A/L Mathaneswaran, Zainal Ariff Bin Abdul Rahman, Yuwaraj Kumar A/L Balakrishnan, Su Tung Tan
  • Patent number: 11127878
    Abstract: A method of depositing a coating layer comprising gallium nitride on a substrate comprising the steps of: (a) providing the substrate having a plurality of side walls and valleys; (b) forming a first layer of gallium nitride deposited on the substrate, by reacting gaseous trimethylgallium and ammonia at a temperature ranging from 400 to 500° C., such that the first layer is formed on the side walls and the valleys; and (c) forming a second layer of gallium nitride deposited on top of the first layer, by reacting gaseous trimethylgallium and ammonia at a temperature ranging from 1000 to 1200° C., to obtain the coating layer comprising the first layer of gallium nitride and the second layer of gallium nitride at a thickness ranging from 3.0 to 4.5 ?m.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: September 21, 2021
    Assignee: Universiti Malaya
    Inventors: Ahmad Shuhaimi Bin Abu Bakar, Mohd Adreen Shah Bin Azman Shah
  • Publication number: 20210080417
    Abstract: The present invention provides device for profiling a biological sample with at least one RNA segment comprising: a metal wire positioned relative to the biological sample such that the sample and the metal wire form a Schottky barrier junction; a bias voltage provider adapted for rectifying the Schottky junction; and; a module for collecting the current over voltage profile of the Schottky junction.
    Type: Application
    Filed: May 30, 2018
    Publication date: March 18, 2021
    Applicant: UNIVERSITI MALAYA
    Inventors: Vengadesh PERIASAMY, Maryam RAJABPOUR NIKNAM, Nastaran RIZAN, Sara TALEBI
  • Publication number: 20200411714
    Abstract: A method of depositing a coating layer comprising gallium nitride on a substrate comprising the steps of: (a) providing the substrate having a plurality of side walls and valleys; (b) forming a first layer of gallium nitride deposited on the substrate, by reacting gaseous trimethylgallium and ammonia at a temperature ranging from 400 to 500° C., such that the first layer is formed on the side walls and the valleys; and (c) forming a second layer of gallium nitride deposited on top of the first layer, by reacting gaseous trimethylgallium and ammonia at a temperature ranging from 1000 to 1200° C., to obtain the coating layer comprising the first layer of gallium nitride and the second layer of gallium nitride at a thickness ranging from 3.0 to 4.5 ?m.
    Type: Application
    Filed: December 13, 2019
    Publication date: December 31, 2020
    Applicant: Universiti Malaya
    Inventors: Ahmad Shuhaimi Bin Abu Bakar, Mohd Adreen Shah Bin Azman Shah
  • Publication number: 20190236984
    Abstract: A three dimensional bio-model for simulating a simulated cranial surgical procedure, the bio-model comprises a synthetic skull layer; a synthetic dura layer under the synthetic skin layer; and a spacer layer between the synthetic skull layer and the synthetic dura layer. The bio-model may be manufactured based on medical image data using three-dimensional printing.
    Type: Application
    Filed: July 12, 2017
    Publication date: August 1, 2019
    Applicant: UNIVERSITI MALAYA
    Inventors: Vickneswaran A/L MATHANESWARAN, Zainal Ariff Bin ABDUL RAHMAN, Yuwaraj Kumar A/L BALAKRISHNAN, Su Tung TAN
  • Publication number: 20190220974
    Abstract: A method of manufacturing a three dimensional bio-model from medical image data is described. The method comprises: identifying a skin layer in the medical image data; determining a thickness of the skin layer; generating three dimensional model data from the medical image data, the three dimensional model data comprising an indication of a synthetic skin layer, the synthetic skin layer comprising a surface layer and a backing layer, wherein a combined thickness of the surface layer and the backing layer is determined from the thickness of the skin layer; and three dimensional printing the three dimensional model data to provide a three dimensional bio-model.
    Type: Application
    Filed: July 12, 2017
    Publication date: July 18, 2019
    Applicant: Universiti Malaya
    Inventors: Vickneswaran A/L MATHANESWARAN, Zainal Ariff Bin ABDUL RAHMAN, Yuwaraj Kumar A/L BALAKRISHNAN, Su Tung TAN
  • Publication number: 20180357931
    Abstract: According to a first aspect of the present invention there is provided a three dimensional bio-model for simulating a surgical procedure. The bio-model comprises a synthetic anatomical structure and a sensor configured to sense a quantity indicative of a characteristic of the simulated surgical procedure. The bio-model may be manufactured based on medical image data using three-dimensional printing.
    Type: Application
    Filed: November 18, 2016
    Publication date: December 13, 2018
    Applicant: UNIVERSITI MALAYA
    Inventors: Vickneswaran A/L MATHANESWARAN, Zainal Ariff Bin ABDUL RAHMAN, Yuwaraj Kumar A/L BALAKRISHNAN, Su Tung TAN
  • Publication number: 20180322809
    Abstract: A bio-model for simulating a surgical procedure comprises a synthetic anatomical structure which has a cavity. A fluid system is coupled to the cavity. In one embodiment the fluid system allows fluid to be pressurized. In one embodiment, the fluid system allows fluid to flow through the cavity. The bio-model may be manufactured based on medical image data using three-dimensional printing.
    Type: Application
    Filed: October 28, 2016
    Publication date: November 8, 2018
    Applicant: UNIVERSITI MALAYA
    Inventors: Vickneswaran A/L MATHANESWARAN, Zainal Ariff Bin ABDUL RAHMAN, Yuwaraj Kumar A/L BALAKRISHNAN, Su Tung TAN
  • Patent number: 9486131
    Abstract: An apparatus for surgery includes a first arm member and a second arm member movable in relation to one another in a same plane through a pivoted portion, in an open and closed position, that is controlled by a pair of handles; at least one through hole is made onto one of the arm members; and a first blade and a second blade, each defined by a tip, a body and a base, perpendicularly extended in parallel from the first and second arm members respectively; wherein both blades have a substantially flat portion started from the tip to the body followed by an expanded portion around the base attached on the arm members that the expanded portion defines a groove therein enclosing the through hole in the closed position.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: November 8, 2016
    Assignee: UNIVERSITI MALAYA
    Inventors: Vickneswaran Mathaneswaran, Hong Guan Ng
  • Patent number: 9475844
    Abstract: A method of producing an agent capable of eliciting immune response against White Spot Syndrome Baculovirus complex in crustaceans of Penaeidae family upon ingestion of the agent comprising the steps of introducing a vector containing genetic sequence of Seq. No 1 into an alga to transform the algae; and cultivating the transformed algae to express modified VP28 peptides according to the genetic sequence of Seq. No. 1 to obtain the agent.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: October 25, 2016
    Assignee: UNIVERSITI MALAYA
    Inventors: Phang Siew Moi, Gan Sook Yee, Ung Eng Huan, Rofina Yasmin Othman, Awang Muhammad Sagaf Abu Bakar
  • Publication number: 20160030206
    Abstract: The present invention relates to a liner for limb prosthesis (100), characterized by a foam layer (102) comprising a plurality of strips of foam (102) and a plurality of elastic fabric layers (101), wherein the foam layer (102) is sandwiched between the elastic fabric layers (101) wherein the liner for limb prosthesis (100) comprises a cylindrical or cone shape, with an open end and one close end.
    Type: Application
    Filed: March 11, 2014
    Publication date: February 4, 2016
    Applicant: Universiti Malaya
    Inventors: Noor Azuan Abu Osman, Hossein Gholizadeh
  • Patent number: 9192640
    Abstract: The present invention relates to a composition having antiviral activity for prophylaxis or treatment of flavivirus infection or a disease resulting therefrom in humans or animals, characterized in that said composition consisting of baicalein, or analogs, or derivatives thereof. The composition may further comprise a pharmaceutically acceptable carrier. The antiviral activity may include inhibition of virus attachment to host cells, inhibition of intracellular virus replication and direct virucidal activity. The flavivirus may comprise dengue virus type-1, dengue virus type-2, dengue virus type-3, dengue virus type-4 and Japanese encephalitis virus.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: November 24, 2015
    Assignee: Universiti Malaya
    Inventor: Sazaly Abu Bakar
  • Patent number: 9175995
    Abstract: An inferential Coriolis mass flowmeter characterized by: a power supply (10); a pressure sensor (11) connected to the power supply (10) and a tube of fluid; a current to voltage converter (13) connected to the pressure sensor (11) for converting a current signal from the pressure sensor (11) to a voltage signal; a controller unit (20) including an analogue to digital converter (21) connected to the current to voltage converter (13) for converting analogue signal from the current to voltage converter (13) to a digital signal, and a microprocessor (22) for processing the digital signal from the analogue to digital converter (21) to determine the mass flowrate of the fluid, wherein the microprocessor (22) is embedded with an algorithm to determine the mass flowrate of a fluid according to equation: y=0.002x4?0.0218x3?0.0865x2?0.8769x?0.0846; a display panel (14) connected to the microprocessor (22); and a transmission circuit (15) connected to the microprocessor (22).
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: November 3, 2015
    Assignee: Universiti Malaya
    Inventor: Mahidzal Dahari
  • Patent number: 8999004
    Abstract: The present invention relates to a coupling device (100) for connecting a residual limb liner (10) to a residual limb socket (20) of a limb prosthesis, characterized by: a magnet assembly (120) comprising a permanent magnet (122) sandwiched by a pair of iron bars (124) for creating a magnetic field; a housing (110) comprising a protrusion (112) for intensifying magnetic field and a cavity (114) for receiving the magnet assembly (120), wherein said housing (110) is embedded at a distal end of the residual limb socket (20); a controlling means (130) coupled to the housing (110) and the magnet assembly (120) for controlling the magnetic field by rotating the magnet assembly (120); and a mounting plate (140) coupled to the residual limb liner (10); wherein the mounting plate (140) is attracted to the protrusion (112) of the housing (110) when the permanent magnet (122) is vertically aligned, thereby attaching the residual limb liner (10) to the residual limb socket (20); and wherein the mounting plate (140) is re
    Type: Grant
    Filed: April 18, 2013
    Date of Patent: April 7, 2015
    Assignee: Universiti Malaya
    Inventors: Madya Noor Azuan Abu Osman, Arezoo Eshraghi
  • Patent number: 8907070
    Abstract: Glycolipids of branched chain alkyl oligosaccharides include a primary alcohol branched in the 2-position and an oligosaccharide, covalently bond to the alcohol in either ?- or ?-linkage (shown in Formula I and Formula II). These compounds show phase behavior not found for the corresponding straight chain counterparts. The properties involve an ambient temperature liquid crystalline appearance and thermotropic liquid crystal phase polymorphism. The formation of cubic phases is considered most interesting with respect to life science applications, e.g. liposomes for drug delivery. Depending on the choice of sugar head group and alkyl tail, various levels of water miscibility may be adjusted to meet applications requirements (complete solubility for emulsifier applications, e.g. cosmetic creams, to limited water swelling only, e.g. for the preparation of artificial membranes).
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: December 9, 2014
    Assignee: Universiti Malaya
    Inventors: Rauzah Hashim, Thorsten Heidelberg, Hind Hassan, Nasrul Zamani Mohd Rodzi, Rusnah Syahila Dauli Hussen, Ahmad Sazali Hamzah, Shahidan Radiman, Volkmar Vill, Matthias Wulf, Seiji Ujiie
  • Patent number: 8895275
    Abstract: A method for producing an aqueous sugar solution from cellulosic materials comprising the steps of heating ground cellulosic materials with perchloric acid; neutralizing the heated materials with an alkali to yield a salt precipitate; and filtering the salt precipitate off to obtain the aqueous sugar solution.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: November 25, 2014
    Assignee: Universiti Malaya
    Inventors: Zainudin Bin Arifin, Teow Chong Teoh
  • Publication number: 20140190274
    Abstract: The present invention relates to an inferential coriolis mass flowmeter characterized by: a power supply (10);a pressure sensor (11) connected to the power supply (10) and a tube of fluid; a current to voltage converter (13) connected to the pressure sensor (11) for converting a current signal from the pressure sensor (11) to a voltage signal; a controller unit (20) including an analogue to digital converter (21) connected to the current to voltage converter (13) for converting analogue signal from the current to voltage converter (13) to a digital signal, and a microprocessor (22) for processing the digital signal from the analogue to digital converter (21) to determine the mass flowrate of the fluid, wherein said microprocessor (22) is embedded with an algorithm to determine the mass flowrate of a fluid according to equation (1): y=0.002x4?0.0218x3+0.0865x2+0.8769x+0.0846 ; a display panel (14) connected to the microprocessor (22); and a transmission circuit (15) connected to the microprocessor (22).
    Type: Application
    Filed: August 17, 2012
    Publication date: July 10, 2014
    Applicant: UNIVERSITI MALAYA
    Inventor: Mahidzal Dahari
  • Patent number: 8741852
    Abstract: Disclosed herein is a peptide for inhibiting growth of bacterial pathogens in a biological sample, characterized by an amino acid sequence selected from a group consisting of Gly-Leu-Phe-Asp-Lys-Trp-Ala-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:1), Gly-Leu-Phe-Asp-Ile-Trp-Ala-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:2), Gly-Leu-Phe-Asp-Ile-Trp-Lys-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID No:3), Gly-Leu-Phe-Asp-Ile-Trp-Lys-Lys-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:4), and Gly-Leu-Phe-Asp-Ile-Trp-Lys-Lys-Leu-Arg-Trp-Arg-Arg (SEQ ID NO:5).
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: June 3, 2014
    Assignee: Universiti Malaya
    Inventors: Shamala Devi Sekaran, Mohd Yasim Md Yusof, Cheng Foh Le
  • Patent number: D801265
    Type: Grant
    Filed: May 23, 2015
    Date of Patent: October 31, 2017
    Assignee: UNIVERSITI MALAYA
    Inventor: Mahidzal Bin Dahari