Patents Assigned to Universiti Malaya
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Patent number: 12000791Abstract: The present invention provides device for profiling a biological sample with at least one RNA segment comprising: a metal wire positioned relative to the biological sample such that the sample and the metal wire form a Schottky barrier junction; a bias voltage provider adapted for rectifying the Schottky junction; and; a module for collecting the current over voltage profile of the Schottky junction.Type: GrantFiled: May 30, 2018Date of Patent: June 4, 2024Assignee: UNIVERSITI MALAYAInventors: Vengadesh Periasamy, Maryam Rajabpour Niknam, Nastaran Rizan, Sara Talebi
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Patent number: 11705020Abstract: A method of manufacturing a three dimensional bio-model from medical image data is described. The method comprises: identifying a skin layer in the medical image data; determining a thickness of the skin layer; generating three dimensional model data from the medical image data, the three dimensional model data comprising an indication of a synthetic skin layer, the synthetic skin layer comprising a surface layer and a backing layer, wherein a combined thickness of the surface layer and the backing layer is determined from the thickness of the skin layer; and three dimensional printing the three dimensional model data to provide a three dimensional bio-model.Type: GrantFiled: July 12, 2017Date of Patent: July 18, 2023Assignee: UNIVERSITI MALAYAInventors: Vickneswaran A/L Mathaneswaran, Zainal Ariff Bin Abdul Rahman, Yuwaraj Kumar A/L Balakrishnan, Su Tung Tan
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Patent number: 11521519Abstract: A cranial bio-model including a skull layer and a dura layer and method of manufacturing a cranial bio-model. A three dimensional bio-model for simulating a simulated cranial surgical procedure, the bio-model comprises a synthetic skull layer, a synthetic dura layer under the synthetic skull layer, and a spacer layer between the synthetic skull layer and the synthetic dura layer. The bio-model may be manufactured based on medical image data using three-dimensional printing.Type: GrantFiled: July 12, 2017Date of Patent: December 6, 2022Assignee: Universiti MalayaInventors: Vickneswaran A/L Mathaneswaran, Zainal Ariff Bin Abdul Rahman, Yuwaraj Kumar A/L Balakrishnan, Su Tung Tan
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Patent number: 11127878Abstract: A method of depositing a coating layer comprising gallium nitride on a substrate comprising the steps of: (a) providing the substrate having a plurality of side walls and valleys; (b) forming a first layer of gallium nitride deposited on the substrate, by reacting gaseous trimethylgallium and ammonia at a temperature ranging from 400 to 500° C., such that the first layer is formed on the side walls and the valleys; and (c) forming a second layer of gallium nitride deposited on top of the first layer, by reacting gaseous trimethylgallium and ammonia at a temperature ranging from 1000 to 1200° C., to obtain the coating layer comprising the first layer of gallium nitride and the second layer of gallium nitride at a thickness ranging from 3.0 to 4.5 ?m.Type: GrantFiled: December 13, 2019Date of Patent: September 21, 2021Assignee: Universiti MalayaInventors: Ahmad Shuhaimi Bin Abu Bakar, Mohd Adreen Shah Bin Azman Shah
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Publication number: 20210080417Abstract: The present invention provides device for profiling a biological sample with at least one RNA segment comprising: a metal wire positioned relative to the biological sample such that the sample and the metal wire form a Schottky barrier junction; a bias voltage provider adapted for rectifying the Schottky junction; and; a module for collecting the current over voltage profile of the Schottky junction.Type: ApplicationFiled: May 30, 2018Publication date: March 18, 2021Applicant: UNIVERSITI MALAYAInventors: Vengadesh PERIASAMY, Maryam RAJABPOUR NIKNAM, Nastaran RIZAN, Sara TALEBI
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Publication number: 20200411714Abstract: A method of depositing a coating layer comprising gallium nitride on a substrate comprising the steps of: (a) providing the substrate having a plurality of side walls and valleys; (b) forming a first layer of gallium nitride deposited on the substrate, by reacting gaseous trimethylgallium and ammonia at a temperature ranging from 400 to 500° C., such that the first layer is formed on the side walls and the valleys; and (c) forming a second layer of gallium nitride deposited on top of the first layer, by reacting gaseous trimethylgallium and ammonia at a temperature ranging from 1000 to 1200° C., to obtain the coating layer comprising the first layer of gallium nitride and the second layer of gallium nitride at a thickness ranging from 3.0 to 4.5 ?m.Type: ApplicationFiled: December 13, 2019Publication date: December 31, 2020Applicant: Universiti MalayaInventors: Ahmad Shuhaimi Bin Abu Bakar, Mohd Adreen Shah Bin Azman Shah
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Publication number: 20190236984Abstract: A three dimensional bio-model for simulating a simulated cranial surgical procedure, the bio-model comprises a synthetic skull layer; a synthetic dura layer under the synthetic skin layer; and a spacer layer between the synthetic skull layer and the synthetic dura layer. The bio-model may be manufactured based on medical image data using three-dimensional printing.Type: ApplicationFiled: July 12, 2017Publication date: August 1, 2019Applicant: UNIVERSITI MALAYAInventors: Vickneswaran A/L MATHANESWARAN, Zainal Ariff Bin ABDUL RAHMAN, Yuwaraj Kumar A/L BALAKRISHNAN, Su Tung TAN
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Publication number: 20190220974Abstract: A method of manufacturing a three dimensional bio-model from medical image data is described. The method comprises: identifying a skin layer in the medical image data; determining a thickness of the skin layer; generating three dimensional model data from the medical image data, the three dimensional model data comprising an indication of a synthetic skin layer, the synthetic skin layer comprising a surface layer and a backing layer, wherein a combined thickness of the surface layer and the backing layer is determined from the thickness of the skin layer; and three dimensional printing the three dimensional model data to provide a three dimensional bio-model.Type: ApplicationFiled: July 12, 2017Publication date: July 18, 2019Applicant: Universiti MalayaInventors: Vickneswaran A/L MATHANESWARAN, Zainal Ariff Bin ABDUL RAHMAN, Yuwaraj Kumar A/L BALAKRISHNAN, Su Tung TAN
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Publication number: 20180357931Abstract: According to a first aspect of the present invention there is provided a three dimensional bio-model for simulating a surgical procedure. The bio-model comprises a synthetic anatomical structure and a sensor configured to sense a quantity indicative of a characteristic of the simulated surgical procedure. The bio-model may be manufactured based on medical image data using three-dimensional printing.Type: ApplicationFiled: November 18, 2016Publication date: December 13, 2018Applicant: UNIVERSITI MALAYAInventors: Vickneswaran A/L MATHANESWARAN, Zainal Ariff Bin ABDUL RAHMAN, Yuwaraj Kumar A/L BALAKRISHNAN, Su Tung TAN
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Publication number: 20180322809Abstract: A bio-model for simulating a surgical procedure comprises a synthetic anatomical structure which has a cavity. A fluid system is coupled to the cavity. In one embodiment the fluid system allows fluid to be pressurized. In one embodiment, the fluid system allows fluid to flow through the cavity. The bio-model may be manufactured based on medical image data using three-dimensional printing.Type: ApplicationFiled: October 28, 2016Publication date: November 8, 2018Applicant: UNIVERSITI MALAYAInventors: Vickneswaran A/L MATHANESWARAN, Zainal Ariff Bin ABDUL RAHMAN, Yuwaraj Kumar A/L BALAKRISHNAN, Su Tung TAN
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Patent number: 9486131Abstract: An apparatus for surgery includes a first arm member and a second arm member movable in relation to one another in a same plane through a pivoted portion, in an open and closed position, that is controlled by a pair of handles; at least one through hole is made onto one of the arm members; and a first blade and a second blade, each defined by a tip, a body and a base, perpendicularly extended in parallel from the first and second arm members respectively; wherein both blades have a substantially flat portion started from the tip to the body followed by an expanded portion around the base attached on the arm members that the expanded portion defines a groove therein enclosing the through hole in the closed position.Type: GrantFiled: June 3, 2009Date of Patent: November 8, 2016Assignee: UNIVERSITI MALAYAInventors: Vickneswaran Mathaneswaran, Hong Guan Ng
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Patent number: 9475844Abstract: A method of producing an agent capable of eliciting immune response against White Spot Syndrome Baculovirus complex in crustaceans of Penaeidae family upon ingestion of the agent comprising the steps of introducing a vector containing genetic sequence of Seq. No 1 into an alga to transform the algae; and cultivating the transformed algae to express modified VP28 peptides according to the genetic sequence of Seq. No. 1 to obtain the agent.Type: GrantFiled: October 31, 2011Date of Patent: October 25, 2016Assignee: UNIVERSITI MALAYAInventors: Phang Siew Moi, Gan Sook Yee, Ung Eng Huan, Rofina Yasmin Othman, Awang Muhammad Sagaf Abu Bakar
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Publication number: 20160030206Abstract: The present invention relates to a liner for limb prosthesis (100), characterized by a foam layer (102) comprising a plurality of strips of foam (102) and a plurality of elastic fabric layers (101), wherein the foam layer (102) is sandwiched between the elastic fabric layers (101) wherein the liner for limb prosthesis (100) comprises a cylindrical or cone shape, with an open end and one close end.Type: ApplicationFiled: March 11, 2014Publication date: February 4, 2016Applicant: Universiti MalayaInventors: Noor Azuan Abu Osman, Hossein Gholizadeh
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Patent number: 9192640Abstract: The present invention relates to a composition having antiviral activity for prophylaxis or treatment of flavivirus infection or a disease resulting therefrom in humans or animals, characterized in that said composition consisting of baicalein, or analogs, or derivatives thereof. The composition may further comprise a pharmaceutically acceptable carrier. The antiviral activity may include inhibition of virus attachment to host cells, inhibition of intracellular virus replication and direct virucidal activity. The flavivirus may comprise dengue virus type-1, dengue virus type-2, dengue virus type-3, dengue virus type-4 and Japanese encephalitis virus.Type: GrantFiled: January 16, 2013Date of Patent: November 24, 2015Assignee: Universiti MalayaInventor: Sazaly Abu Bakar
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Patent number: 9175995Abstract: An inferential Coriolis mass flowmeter characterized by: a power supply (10); a pressure sensor (11) connected to the power supply (10) and a tube of fluid; a current to voltage converter (13) connected to the pressure sensor (11) for converting a current signal from the pressure sensor (11) to a voltage signal; a controller unit (20) including an analogue to digital converter (21) connected to the current to voltage converter (13) for converting analogue signal from the current to voltage converter (13) to a digital signal, and a microprocessor (22) for processing the digital signal from the analogue to digital converter (21) to determine the mass flowrate of the fluid, wherein the microprocessor (22) is embedded with an algorithm to determine the mass flowrate of a fluid according to equation: y=0.002x4?0.0218x3?0.0865x2?0.8769x?0.0846; a display panel (14) connected to the microprocessor (22); and a transmission circuit (15) connected to the microprocessor (22).Type: GrantFiled: August 17, 2012Date of Patent: November 3, 2015Assignee: Universiti MalayaInventor: Mahidzal Dahari
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Patent number: 8999004Abstract: The present invention relates to a coupling device (100) for connecting a residual limb liner (10) to a residual limb socket (20) of a limb prosthesis, characterized by: a magnet assembly (120) comprising a permanent magnet (122) sandwiched by a pair of iron bars (124) for creating a magnetic field; a housing (110) comprising a protrusion (112) for intensifying magnetic field and a cavity (114) for receiving the magnet assembly (120), wherein said housing (110) is embedded at a distal end of the residual limb socket (20); a controlling means (130) coupled to the housing (110) and the magnet assembly (120) for controlling the magnetic field by rotating the magnet assembly (120); and a mounting plate (140) coupled to the residual limb liner (10); wherein the mounting plate (140) is attracted to the protrusion (112) of the housing (110) when the permanent magnet (122) is vertically aligned, thereby attaching the residual limb liner (10) to the residual limb socket (20); and wherein the mounting plate (140) is reType: GrantFiled: April 18, 2013Date of Patent: April 7, 2015Assignee: Universiti MalayaInventors: Madya Noor Azuan Abu Osman, Arezoo Eshraghi
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Patent number: 8907070Abstract: Glycolipids of branched chain alkyl oligosaccharides include a primary alcohol branched in the 2-position and an oligosaccharide, covalently bond to the alcohol in either ?- or ?-linkage (shown in Formula I and Formula II). These compounds show phase behavior not found for the corresponding straight chain counterparts. The properties involve an ambient temperature liquid crystalline appearance and thermotropic liquid crystal phase polymorphism. The formation of cubic phases is considered most interesting with respect to life science applications, e.g. liposomes for drug delivery. Depending on the choice of sugar head group and alkyl tail, various levels of water miscibility may be adjusted to meet applications requirements (complete solubility for emulsifier applications, e.g. cosmetic creams, to limited water swelling only, e.g. for the preparation of artificial membranes).Type: GrantFiled: November 5, 2012Date of Patent: December 9, 2014Assignee: Universiti MalayaInventors: Rauzah Hashim, Thorsten Heidelberg, Hind Hassan, Nasrul Zamani Mohd Rodzi, Rusnah Syahila Dauli Hussen, Ahmad Sazali Hamzah, Shahidan Radiman, Volkmar Vill, Matthias Wulf, Seiji Ujiie
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Patent number: 8895275Abstract: A method for producing an aqueous sugar solution from cellulosic materials comprising the steps of heating ground cellulosic materials with perchloric acid; neutralizing the heated materials with an alkali to yield a salt precipitate; and filtering the salt precipitate off to obtain the aqueous sugar solution.Type: GrantFiled: January 29, 2010Date of Patent: November 25, 2014Assignee: Universiti MalayaInventors: Zainudin Bin Arifin, Teow Chong Teoh
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Publication number: 20140190274Abstract: The present invention relates to an inferential coriolis mass flowmeter characterized by: a power supply (10);a pressure sensor (11) connected to the power supply (10) and a tube of fluid; a current to voltage converter (13) connected to the pressure sensor (11) for converting a current signal from the pressure sensor (11) to a voltage signal; a controller unit (20) including an analogue to digital converter (21) connected to the current to voltage converter (13) for converting analogue signal from the current to voltage converter (13) to a digital signal, and a microprocessor (22) for processing the digital signal from the analogue to digital converter (21) to determine the mass flowrate of the fluid, wherein said microprocessor (22) is embedded with an algorithm to determine the mass flowrate of a fluid according to equation (1): y=0.002x4?0.0218x3+0.0865x2+0.8769x+0.0846 ; a display panel (14) connected to the microprocessor (22); and a transmission circuit (15) connected to the microprocessor (22).Type: ApplicationFiled: August 17, 2012Publication date: July 10, 2014Applicant: UNIVERSITI MALAYAInventor: Mahidzal Dahari
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Patent number: D801265Type: GrantFiled: May 23, 2015Date of Patent: October 31, 2017Assignee: UNIVERSITI MALAYAInventor: Mahidzal Bin Dahari