Abstract: The present invention relates to a gallium-doped phosphocalcic compound of formula (I): Ca(10.5-1.5x)Gax(PO4)7??(I) wherein 0<x<1 and the salts, hydrates and mixtures thereof. The invention further relates to a solid state process and a process in solution for the manufacture of such compounds and the use thereof for the preparation of a biomaterial, in particular a self-setting calcium-phosphate cement (CPC).
Type:
Grant
Filed:
December 2, 2013
Date of Patent:
December 30, 2014
Assignees:
Graftys SA, University de Nantes, Centre National de la Recherche Scientifique
Inventors:
Bruno Bujoli, Jean-Michel Bouler, Pascal Janvier, Ibrahim Khairoun, Verena Schnitzler
Abstract: The present invention relates to a galliated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I): Ca(10.5-1.5x)Gax(PO4)7??(I) wherein 0<x<1 and the salts, hydrates and mixtures thereof and/or a calcium deficient apatite structure with in particular a (Ca+Ga)/P molar ratio in the range of 1.3 to 1.67, and a gallium content up to 4.5% by weight. It also relates to processes of preparation of such materials and uses thereof, in particular as dental or bony implants. It further relates to a kit comprising a galliated calcium-phosphate biomaterial in combination with a fluid component. It finally relates to methods of use of the galliated calcium-phosphate biomaterial, notably for III) ions increase radio-opacity after bone implantation and can be released for inhibiting bone resorption.
Type:
Grant
Filed:
March 3, 2010
Date of Patent:
November 25, 2014
Assignees:
Centre National de la Recherche Scientifique (C.N.R.S.), University de Nantes, Graftys
Inventors:
Bruno Bujoli, Jean-Michel Bouler, Pascal Janvier, Ibrahim Khairoun, Verena Schnitzler, Charlotte Mellier
Abstract: A device providing biological protection against the electromagnetic waves emitted by a mobile telephone. A protective element against electromagnetic waves, arranged so that the user is able to protect himself or herself from the electromagnetic waves emitted by the mobile telephone during use, with the protective element reflecting these signals away from the user.
Type:
Grant
Filed:
October 22, 2009
Date of Patent:
December 11, 2012
Assignees:
Dephasium Ltd., University de Nantes
Inventors:
Cyril Mourali, Serge Parienti, Joseph Saillard, Janic Chauveau, Marc Brunet, Henri Collette