Abstract: The instant methods pertain to improved methods for storing neural cells, preferably dissociated neural cells, prior to their use in transplantation and to the cells obtained using such methods. One embodiment pertains to methods for storing the neural cells in medium lacking added buffer or added protein, other embodiments feature neural cells which are maintained at 4° C. prior to cryopreservation and have comparable viability and/or functionality to freshly harvest cells. In addition, methods for storing and/or transplantation of porcine neural cells are described.
Type:
Grant
Filed:
August 17, 2001
Date of Patent:
November 23, 2004
Assignees:
University Hospital Groningen, Inc., Diacrin, Inc.
Inventors:
Jan Koopmans, Douglas B. Jacoby, Jonathan Dinsmore