Patents Assigned to University Industry Foundation, Yonsei University Wonju Campus
  • Patent number: 11974970
    Abstract: A muscular atrophy-inducing agent containing, as an active ingredient, a hypometabolism-inducing substance selected from the group consisting of 3-iodothyronamine (T1AM), [D-Ala2,D-Leu5] enkephalin (DADLE), 5?-adenosine monophosphate (5?-AMP), and hydrogen sulfide (H2S), and a method for preventing or treating muscular hypertrophy; and a method for shrinking facial muscle are proposed. The muscular atrophy study model can provide a study model for an economic muscular atrophy study by using a hypometabolism-inducing substance which can be mass-produced, has an effect which may be usefully used by verification for screening of a drug for preventing or treating muscular atrophy, and can be usefully used as a compositions for preventing or treating muscular hypertrophy and a composition for facial muscle shrinkage through the muscular atrophy effect.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: May 7, 2024
    Assignee: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Inho Choi, Chan-Moon Chung
  • Patent number: 11944731
    Abstract: A dialyzer control apparatus includes a magnetic field generator which is disposed on an outer surface of a dialyzer which removes wastes from a blood flowing therein and generates a magnetic field; and a controller which controls the magnetic field generator to perform a magnetic field stimulation on the blood flowing into the dialyzer. The magnetic field stimulation may be a stimulation related to the improvement of the Rouleaux formation for the red blood cells in the blood.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: April 2, 2024
    Assignee: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Yong Heum Lee, Na Ra Lee, Soo Yong Lee, Ja Woo Lee
  • Publication number: 20240105344
    Abstract: The present invention relates to a system for constructing a hyperkalemia prediction algorithm through an electrocardiogram, a method for constructing the hyperkalemia prediction algorithm through the electrocardiogram by using the same, and a hyperkalemia prediction system using the electrocardiogram, and the system for constructing a hyperkalemia prediction algorithm through an electrocardiogram includes: a data collection unit collecting electrocardiogram data of multiple hyperkalemia patients; a data processing unit generating a training dataset for machine learning based on the electrocardiogram data collected by the data collection unit; and a model generation unit constructing a neural network model for predicting a hyperkalemia using an electrocardiogram based on the training dataset provided by the data processing unit.
    Type: Application
    Filed: December 4, 2023
    Publication date: March 28, 2024
    Applicant: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Hyun YOUK, Sang Won HWANG, ERDENEBAYAR URTNASAN
  • Patent number: 11860186
    Abstract: Provided are a fall detection apparatus and method. The fall detection method may include measuring first to third accelerations corresponding to a user, measuring first to third angular velocities corresponding to the user, determining an acceleration value for the user based on at least one of the first to third accelerations, determining an angular velocity value for the user based on at least one of the first and second angular velocities, determining an angle value for the user based on at least one of the first to third accelerations, calculating a triangle feature using the acceleration value, and detecting a fall of the user based on at least one of the acceleration value, the angular velocity value, the angle value, and the triangle feature.
    Type: Grant
    Filed: October 12, 2021
    Date of Patent: January 2, 2024
    Assignee: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Youngho Kim, Jongman Kim, Bummo Koo, Hanul Jeong, Soonjae Ahn, Seongjung Kim
  • Publication number: 20230270788
    Abstract: The present application pertains to a sialyloligosaccharide for augmenting the stemness of stem cells and a use thereof and provides a composition for augmenting stemness of stem cells, a method of culturing stem cells in a medium containing a sialyloligosaccharide, a method of augmenting stemness of stem cells, a stem cell with augmented stemness, obtained by the method, and a cell therapy composition including the stem cells as an active ingredient. The composition or the method according to one or more embodiments may suppress the aging of stem cells and may maintain and augment stemness.
    Type: Application
    Filed: October 8, 2020
    Publication date: August 31, 2023
    Applicants: GENECHEM INC., UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS, INDUSTRY-ACADEMIC COOPERATION FOUNDATION,YONSEI UNIVERSITY
    Inventors: Sung Hoon KIM, Ah Reum BAEK, Sung Rae CHO, Jin Suk WOO, Li La KIM, Dae Hee KIM
  • Patent number: 11679134
    Abstract: The present invention relates to a pharmaceutical composition, a food composition, and a food additive for the prevention and treatment or improvement of muscle loss, muscle weakness, and muscle atrophy, which contain Enterococcus faecalis, particularly Enterococcus faecalis EF-2001 among others, a culture solution thereof, or a killed body thereof as an active ingredient. Killed Enterococcus faecalis EF-2001 of the present invention exhibits a remarkable treatment effect for muscle loss, muscle weakness, and muscle atrophy by inhibiting the damage to muscle cells induced by oxidative stress, and thus killed lactic acid bacterium Enterococcus faecalis EF-2001 of the present invention or a culture solution thereof can be usefully used as an active ingredient in a pharmaceutical composition, a food composition, and a food additive for prevention of muscle atrophy and sarcopenia.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: June 20, 2023
    Assignees: KOREA BERM CO., LTD., UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS, NIHON BERUMU CO., LTD.
    Inventors: Tack Joong Kim, Myung Hun Lee, Masahiro Iwasa, Kwon il Han, Wan Jae Kim
  • Publication number: 20230128338
    Abstract: An apparatus for imaging examination of cells on a surface of living tissue using moxifloxacin includes: a light source emitting light towards living tissue stained with moxifloxacin; a photographing unit photographing the living tissue subjected to fluorescence excitation by the light emitted from the light source; a lens unit controlling the light emitted from the light source or a fluorescence path of moxifloxacin excited by the light; an objective lens controlling a focus of the photographing unit; an active lens disposed between the objective lens and the photographing unit and changing a focal position on the living tissue; and an image generator performing image processing of a cell image of the living tissue photographed by the photographing unit to generate an in-focus image, in which the entirety of the cell image is in focus.
    Type: Application
    Filed: January 24, 2022
    Publication date: April 27, 2023
    Applicants: POSTECH Research and Business Development Foundation, SEOUL NATIONAL UNIVERSITY HOSPITAL, UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Ki Hean KIM, Jung Bin LEE, Seong Han KIM, Chang Ho YOON, Sejung Yang
  • Patent number: 11607131
    Abstract: Provided is an apparatus for measuring implant osseointegration, and the apparatus for measuring implant osseointegration includes: a vibration generation unit configured to apply multiple vibrations with frequencies in different bands, respectively, to an implant fixture; a vibration sensor configured to measure three-axis vibration information of the implant fixture caused by the vibrations from the vibration generation unit; and a control unit configured to determine the degree of osseointegration based on the measured vibration information.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: March 21, 2023
    Assignee: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Yong Heum Lee, Soo Byeong Kim, Na Ra Lee
  • Publication number: 20220112515
    Abstract: Disclosed herein are methods for producing virus-infected cell lines or animal models, wherein an enveloped virus including a lipid bilayer is mixed with a bile acid or a bile acid derivative, which allows the lipid bilayer to be replaced with a lipid bilayer derived from a target animal. Also disclosed herein are the virus-infected cell lines or animal models so produced and methods of screening a therapeutic candidate for a viral disease using the same.
    Type: Application
    Filed: October 25, 2019
    Publication date: April 14, 2022
    Applicants: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Hong Jai Lee, Soo Ki Kim, Jae Seung Moon, Bo Young Shin, Jin Su Shin, Sang Kyou Lee
  • Patent number: 11129567
    Abstract: A portable nystagmus examination device includes: a main body which is provided in the form of goggles and comes into contact with the face of a subject so that the visual field of the subject is blocked from the outside; a camera unit which is provided on the inner side of the main body and captures eyeball image information on the subject; a monitor unit which is provided on the outer side of the main body and displays, to a user, the eyeball image information on the subject captured through the camera unit; and a control unit which is provided in the main body, collects the eyeball image information on the subject captured by the camera unit, and controls the monitor unit to output the eyeball image information. Thus, the user can perform the nystagmus examination regardless of a place.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: September 28, 2021
    Assignee: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventor: Young Joon Seo
  • Patent number: 11097240
    Abstract: The present invention relates to a pickering emulsion composition using polyimide particles and a method for preparing the same. The pickering emulsion stabilized by the polyimide particles according to the present invention has a very stable dispersed phase and does not cause flocculation, creaming, coalescence and phase separation even after a long time, and has an advantage of being capable of forming both an oil-in-water type emulsion and a water-in-oil type emulsion. Further, the polyimide particles used in the present invention can be synthesized in a simple manner and have partial wettability without the surface treatment and pH control so that they can be easily used for the emulsion stabilization.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: August 24, 2021
    Assignees: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS, RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
    Inventors: Chan Moon Chung, Kwang Myong Lee, Yu Jin Cho, Ju Young Choi, Beom Jun Kim, Jin Won Jeong, Dong Min Kim
  • Patent number: 10821086
    Abstract: The present invention relates to: a muscular atrophy-inducing agent containing, as an active ingredient, a hypometabolism-inducing substance selected from the group consisting of 3-iodothyronamine (T1AM), [D-Ala2,D-Leu5] enkephalin (DADLE), 5?-adenosine monophosphate (5?-AMP), and hydrogen sulfide (H2S); a method for preparing a muscular atrophy study model comprising inducing muscular atrophy by administering the muscular atrophy-inducing agent; a study model prepared by the method; a screening method for a drug for preventing or treating muscular atrophy using the same; a composition for preventing or treating muscular hypertrophy; and a composition for facial muscle shrinkage.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: November 3, 2020
    Assignee: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Inho Choi, Kyoungsook Park, Hyun Woo Ju
  • Patent number: 10685219
    Abstract: Provided is a sign language recognition system, and the sign language recognition system includes an acquisition unit configured to acquire an electromyogram signal of a user from a sensor measurement device worn around an arm of the user, an extraction unit configured to extract a muscle active section from the electromyogram signal to detect a sign language gesture of the user, a producing unit configured to produce a first feature vector by performing signal processing to the muscle active section, a search unit configured to search a signal corresponding to the first feature vector in a database, and an output unit configured to output a text corresponding to the searched signal.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: June 16, 2020
    Assignee: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Young Ho Kim, Seong Jung Kim, Han Soo Lee, Jong Man Kim, Min Jo, Eun Kyoung Choi, Soon Jae Ahn, Young Jae Jeong
  • Publication number: 20190192003
    Abstract: Provided is an apparatus for measuring implant osseointegration, and the apparatus for measuring implant osseointegration includes: a vibration generation unit configured to apply multiple vibrations with frequencies in different bands, respectively, to an implant fixture; a vibration sensor configured to measure three-axis vibration information of the implant fixture caused by the vibrations from the vibration generation unit; and a control unit configured to determine the degree of osseointegration based on the measured vibration information.
    Type: Application
    Filed: May 23, 2017
    Publication date: June 27, 2019
    Applicant: UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Yong Heum LEE, Soo Byeong KIM, Na Ra LEE
  • Patent number: 10330576
    Abstract: A sensor for measuring shear force and a dummy for testing a vehicle using the same are provided herein. A sensor for measuring shear force which is configured to quantitatively accurately measure shear force applied to a human body who sits on a vehicle seat, and a dummy for measuring shear force using the sensor are provided, wherein the sensor for measuring shear force includes an upper block, an intermediate block and a lower block and is configured such that a first strain gauge is mounted upright between the upper block and the intermediate block and a second strain gauge is mounted upright between the intermediate block and the lower block so that the shear force can be accurately measured without being affected by horizontal tensile force.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: June 25, 2019
    Assignees: Hyundai Motor Company, Kia Motors Corporation, University Industry Foundation, Yonsei University Wonju Campus
    Inventors: Tae Uk Kang, Han Sung Kim, Seong Guk Kim, Dong Hyun Kim, Dong Hyun Hwang, Han A. Lee, Ye Eun Song
  • Patent number: 10072302
    Abstract: There are provided an improved cervical cancer diagnosing method and a diagnostic kit for same. According to the present invention, it is possible to more rapidly and accurately provide a patient group requiring a clinical treatment and a prevention treatment in terms of a technical aspect to predict that the limitation of the existing HPV DNA test method can be overcome, automate the RNA extraction from eliminated cells, and more rapidly provide more objective and accurate results because the result analysis can be performed by software by using the real-time RT-PCR.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: September 11, 2018
    Assignees: OPTIPHARM.CO., LTD., UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Hye Young Lee, Hye Young Wang
  • Publication number: 20180164198
    Abstract: A sensor for measuring shear force and a dummy for testing a vehicle using the same are provided herein. A sensor for measuring shear force which is configured to quantitatively accurately measure shear force applied to a human body who sits on a vehicle seat, and a dummy for measuring shear force using the sensor are provided, wherein the sensor for measuring shear force includes an upper block, an intermediate block and a lower block and is configured such that a first strain gauge is mounted upright between the upper block and the intermediate block and a second strain gauge is mounted upright between the intermediate block and the lower block so that the shear force can be accurately measured without being affected by horizontal tensile force.
    Type: Application
    Filed: August 30, 2017
    Publication date: June 14, 2018
    Applicants: Hyundai Motor Company, Kia Motors Corporation, University Industry Foundation, Yonsei University Wonju Campus
    Inventors: Tae Uk KANG, Han Sung KIM, Seong Guk KIM, Dong Hyun KIM, Dong Hyun HWANG, Han A. LEE, Ye Eun SONG
  • Patent number: 9839880
    Abstract: A water treatment device using a hollow fiber membrane module is provided, including: a water container filled with raw water; a hollow fiber membrane module installed in the water container and provided with hollow fiber membranes therein to perform water treatment by a water pressure difference; and a raw water supplying part positioned on the water container, and configured to supply the raw water into the water container through the hollow fiber membrane module, in which the hollow fiber membrane module causes the raw water supplied from the raw water supplying part collide with the hollow fiber membrane to move the hollow fiber membrane, so that it is possible to minimize contamination of the hollow fiber membrane, minimize use of energy using electricity, and wash the hollow fiber membrane by a physical method.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: December 12, 2017
    Assignee: UNIVERSITY INDUSTRY FOUNDATION YONSEI UNIVERSITY WONJU CAMPUS
    Inventors: Soo Hong Noh, Jong Hun Lee, Danhong Kim, Jong chan Yi
  • Publication number: 20170211156
    Abstract: There are provided an information offering method for diagnosing breast cancer comprising: (a) separating total RNA from a cell obtained from a tissue or blood of a suspected cancer patient; (b) synthesizing a cDNA from the separated total RNA; (c) performing a real-time PCR with the synthesized cDNA by using primer pair mix and probe mix that can amplify human epidermal growth factor receptor 2 (HER2); wherein, the primer pair mix that can amplify human epidermal growth factor receptor 2 (HER2) are described as SEQ ID Nos.:1 and 2, 3 and 4, and 6 and 7 and the probe mix are described as SEQ ID Nos.: 5, 8, and 9.
    Type: Application
    Filed: March 9, 2017
    Publication date: July 27, 2017
    Applicants: Optipharm Co., Ltd., University Industry Foundation, Yonsei University Wonju Campus
    Inventors: Hye Young Lee, Seung Il Kim, Hye Young Wang, Sang Jung Park