Patents Assigned to University of Arizona
  • Patent number: 11987564
    Abstract: Disclosed are small molecule PTPRD inhibitors and uses thereof. Methods of using the PTPRD inhibitors include methods of treating, preventing, or delaying the progression of a disorder responsive to PTPRD inhibition, including for example nicotine dependence, addiction, obesity, metabolic syndrome, and substance-use disorders such as stimulant-use disorders and opioid-use disorders.
    Type: Grant
    Filed: May 2, 2022
    Date of Patent: May 21, 2024
    Assignees: Arizona Board of Regents on Behalf of the University of Arizona, The United States Government as respresented by the Department of Veterans Affairs, The University of Kentucky Research Foundation
    Inventors: George Richard Uhl, Ian M. Henderson, Wei Wang, Thomas Prisinzano
  • Publication number: 20240160001
    Abstract: Imaging a distribution of one or more optical sources includes: receiving respective optical signals from a spatial mode sorter during each of two or more detection intervals of time; after each of the two or more detection intervals of time, processing information based at least in part on: (1) the respective optical signal received in the corresponding detection interval of time, and (2) a first set of models comprising a set of distributions related to one or more optical sources, each model corresponding to a different number of optical sources in the distribution, and configuring the spatial mode sorter based at least in part on the processing; and providing an estimated measurement characterizing the distribution of one or more optical sources based at least in part on the processed information. The processing after at least one of the two or more detection intervals of time includes computing an eigen-projection.
    Type: Application
    Filed: May 6, 2022
    Publication date: May 16, 2024
    Applicant: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Kwan Kit Lee, Michael Grace, Amit Ashok, Saikat Guha
  • Publication number: 20240159432
    Abstract: A system for providing a contour map of the surface of a heliostat from reflected sunlight using a fly's eye camera. The system includes an entrance screen configured to receive sunlight reflected by said heliostat; an array of imaging apertures extending across the entrance screen, each aperture forming an image of said heliostat from a different viewpoint to provide a plurality of heliostat images; one or more digital cameras configured to view all of said plurality of heliostat images; an image processor configured to map out from the plurality of heliostat images a location of sunlight delivered to the entrance screen to obtain a plurality of maps, and to provide, based on centroids of said maps a tip and tilt of each said subsection The reflecting surface profile of the heliostat is obtained by integration of the subsection tilts across all the subsections.
    Type: Application
    Filed: March 8, 2022
    Publication date: May 16, 2024
    Applicant: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Ryker EADS, James Roger P . Angel
  • Patent number: 11981421
    Abstract: A system and method for controlling boundary layer transition for a high-speed vehicle are disclosed. The method includes determining a location of onset of boundary-layer transition that naturally develops during high-speed flight of the high-speed vehicle, and providing a pair of flow control strips at a surface/wall/skin of the high-speed vehicle such that the boundary-layer transition is delayed or prevented during high-speed flight of the high-speed vehicle. The delayed or prevented locations of the transition result in a change in the high-speed boundary layer during the high-speed flight of the high-speed vehicle. The change in the high-speed boundary layer transition affects skin friction drag, aero-thermodynamic heating, and pressure fluctuations in the boundary layer of the high-speed vehicle.
    Type: Grant
    Filed: December 24, 2020
    Date of Patent: May 14, 2024
    Assignee: Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Hermann F. Fasel, Christoph Hader
  • Patent number: 11980698
    Abstract: Disclosed herein are contractile cell constructs, methods for using them to treat disease, and methods for making them.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: May 14, 2024
    Assignees: Arizona Board of Regents on Behalf of the University of Arizona, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Jordan J. Lancaster, Steven Goldman
  • Patent number: 11977047
    Abstract: This present disclosure is directed to a silver metal wire coated with silver sulfide reference electrode, the preparation via anodization of a silver metal wire in a sodium and/or potassium sulfide solution and use thereof, including test methods to measure corrosion in test articles such as metal pipes. The reference electrode exhibits good stability characteristics, including stability under high temperature conditions.
    Type: Grant
    Filed: August 30, 2021
    Date of Patent: May 7, 2024
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Dominic Francis Gervasio, Kalin Denton, Gil-Pyo Kim, Vlad Alex Sasaran, Nicholas Michael McEvoy, Alexis Gray
  • Patent number: 11969401
    Abstract: The disclosure provides methods for treating or limiting development age-related macular degeneration, comprising (a) a GPR143 receptor agonist, including but not limited to L-DOPA, L-DOPA analogues, or a pharmaceutically acceptable salt thereof, and (b) melatonin, a melatonin analogue, or a pharmaceutically acceptable salt thereof, and related compositions.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: April 30, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Robert Snyder, Brian McKay
  • Patent number: 11970521
    Abstract: Peptide analogues of ?-amyloid and methods of using said analogues for neuroprotection are described herein. The ?-amyloid peptide analogues have a sequence that is at least 50% identical to an N-terminal ?-amyloid core fragment. A pharmaceutical composition of the ?-amyloid peptide analogues in a pharmaceutically acceptable carrier can be administered to a subject for neuromodulation. The ?-amyloid peptide analogues, while lacking neurotoxicity, effectively provides for protective activity against ?-amyloid toxicity.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: April 30, 2024
    Assignees: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, UNIVERSITY OF HAWAII
    Inventors: Robert A. Nichols, Kelly Forest, Victor J. Hruby
  • Publication number: 20240135219
    Abstract: A signal comprises a plurality of codewords associated with a set of codewords, each codeword comprising a plurality of symbols associated with a symbol constellation. Processing includes: mapping quantum states associated with symbols of a particular codeword of the signal to a plurality of input qubits, and applying quantum operations to the input qubits according to a quantum circuit for decoding the signal. The quantum operations comprise: controlled unitary multi-qubit operations performed on two or more qubits in a first set of qubits controlled based on two or more qubits in a second set of qubits, an initial quantum measurement performed on an initially measured qubit in the first set of qubits, at least one controlled unitary single-qubit operation performed on a post-measurement state associated with the initially measured qubit, and quantum operations that invert at least a portion of the operations in the plurality of controlled unitary multi-qubit operations.
    Type: Application
    Filed: January 25, 2022
    Publication date: April 25, 2024
    Applicants: Arizona Board of Regents on Behalf of the University of Arizona, Duke University
    Inventors: Narayanan Rengaswamy, Kaushik Seshadreesan, Saikat Guha, Henry Pfister
  • Patent number: 11957480
    Abstract: Computer-implemented systems and methods for sleep optimization are disclosed. In certain embodiments, the system includes one or more peripheral devices, a network, one or more networked computers, and one or more remote servers. The peripheral devices and/or the networked computers collect one or more types of sleep data, calculate one or more sleep parameters, and transmit said sleep parameters to the one or more remote servers. The remote servers then perform calculations to determine optimal sleep recommendations. The sleep recommendations are then output to one or more networked computers and/or one or more peripheral devices as adjustments to sleep time and sleep duration.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: April 16, 2024
    Assignees: Arizona Board of Regents on Behalf of the University of Arizona, The Trustees of the University of Pennsylvania
    Inventors: Michael Grandner, Michael Perlis
  • Patent number: 11960815
    Abstract: Various examples are provided related to automated chip design, such as a pareto-optimization framework for automated network-on-chip design. In one example, a method for network-on-chip (NoC) design includes determining network performance for a defined NoC configuration comprising a plurality of n routers interconnected through a plurality of intermediate links; comparing the network performance of the defined NoC configuration to at least one performance objective; and determining, in response to the comparison, a revised NoC configuration based upon iterative optimization of the at least one performance objective through adjustment of link allocation between the plurality of n routers. In another example, a method comprises determining a revised NoC configuration based upon iterative optimization of at least one performance objective through adjustment of a first number of routers to obtain a second number of routers and through adjustment of link allocation between the second number of routers.
    Type: Grant
    Filed: January 3, 2023
    Date of Patent: April 16, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventor: Wolfgang Fink
  • Patent number: 11962127
    Abstract: External cavity laser systems are described that can operate with essentially no mode hopping. One example configuration of the laser system includes a semiconductor laser device, a folded cavity external to the semiconductor laser device, where at the semiconductor laser device is positioned at a fold in the folded cavity. In this configuration, at least one mirror is positioned in the folded cavity to enable sustained propagation of light within the folded cavity, and at least two polarization elements are positioned in the folded external cavity. The polarization elements cause a polarization state of the light that impinges in different directions on each semiconductor laser device that is positioned at a fold to be orthogonal to one another, thus eliminating or substantially reducing mode hopping in the laser output.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: April 16, 2024
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventor: Yushi Kaneda
  • Patent number: 11957096
    Abstract: The systems and methods described herein relate to fully or partially autonomous or remotely operated aerial pollination vehicles that use computer vision and artificial intelligence to automatically detect plants, orient the vehicle to a pollen dispensing position above each plant, and pollinate the individual plants.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: April 16, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Kyle Tabor Norland, Mitzy Oros, Evan Westman
  • Patent number: 11955676
    Abstract: A unit configured as constituent part of a fuel cell for use in novel electrochemical hydrogen compressor material technology system includes a combination of a hydrocarbon auto-thermal reformer, a water-gas shift reactor, and at least two countercurrent flow heat recuperators at least one of which is downstream from both the reformer and reactor. Optionally, two of the at least two recuperators are separated by the reactor to generate H2 in addition to that already contained in reformate formed at the reformer. The unit may include a proton conducting membrane that includes an inorganic polymer with pores filled with an organic polymer, each of which is configured to operate individually within a wide range of temperatures with no added solvent.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: April 9, 2024
    Assignee: Arizona Board of Regents on behalf of The University of Arizona
    Inventors: Peiwen Li, Xinhai Xu, Shuyang Zhang, Xiaoxin Wang
  • Patent number: 11952379
    Abstract: This invention is in the field of medicinal pharmacology. In particular, the invention relates to a new class of small-molecules having a pyrazino-pyrimidine-dione (or related) structure which function as modulators (activators, inhibitors) of protease activated receptor type 2 (PAR2), and their use as therapeutics for the treatment of conditions involving PAR2 activity (e.g., asthma, chronic pain, cancer and/or vascular disorders).
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: April 9, 2024
    Assignees: Arizona Board of Regents on Behalf of the University of Arizona, Board of Regents, The University of Texas System
    Inventors: Scott A. Boitano, Josef Vagner, Theodore J. Price, Greg Dussor
  • Patent number: 11950026
    Abstract: A light projection system including a light source and a light controller to generate modulatable beams of light and an angular light modulator (ALM) positioned to selectively direct the light from each beam. The light controller can be a spatial light modulator or a processor programmed to control light output. The angular light modulator may be a digital micromirror device (DMD). The ALM may be configured to direct the images into diffraction orders or using scanning the images. A LIDAR system to detect a position of an object including a first source of a two-dimensional array of beams of light and ALM to project light into a selected one of a plurality of directions. An illumination system, comprising a first angular-spatial light modulator (ASLM) and a second ASLM system configured such a first beam and a second beam of light intersect.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: April 2, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Yuzuru Takashima, Brandon Hellman, Braden Smith
  • Patent number: 11947128
    Abstract: A gaze tracking platform for human-machine interface device, such as a wearable Augmented Reality Near-to-Eye Display. The gaze tracking method, digital illumination assisted analog feedback tracking employs neither auxiliary camera nor digital image processing of human eye image that confronts challenges in gaze tracking speed, power, cost and space. Instead, an analog-digital hybrid method to track the gaze inspired by the groove tracking method that is widely adopted for optical data storage systems. In the method, a digital micromirror device generates angular modulated and infrared illuminating beam. The cornea reflects the infrared light and a segmented photodiode detects the reflection while providing a feedback servo signal to the digital micromirror device controller. The feedback signal is integrated over a time provides the variation gaze. Moreover, infrared and angularly modulated illumination is time-multiplexed with information displayed in visible wavelength.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: April 2, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventor: Yuzuru Takashima
  • Publication number: 20240103908
    Abstract: Provided herein are dynamic adaptive scheduling (DAS) systems. In some embodiments, the DAS systems include a first scheduler, a second scheduler that is slower than the first scheduler, and a runtime preselection classifier that is operably connected to the first scheduler and the second scheduler, which runtime preselection classifier is configured to effect selective use of the first scheduler or the second scheduler to perform a given scheduling task. Related systems, computer readable media, and additional methods are also provided.
    Type: Application
    Filed: September 19, 2023
    Publication date: March 28, 2024
    Applicants: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, WISCONSIN ALUMNI RESEARCH FOUNDATION, UNIVERSITY OF ARIZONA, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Chaitali CHAKRABARTI, Umit OGRAS, Ahmet GOKSOY, Anish KRISHNAKUMAR, Ali AKOGLU, Md Sahil HASSAN, Radu MARCULESCU, Allen-Jasmin FARCAS
  • Patent number: 11937561
    Abstract: Modular cultivation systems utilized in a Vertical Farm or Plant Factory is described herein. The modular cultivation system has a growing module that includes an expandable and collapsible support frame with growing boards or pods, lighting boards, and an irrigation system arranged within the support frame to maximize the quantity of crops that can be grown within an available volume of space in a Vertical Farm unit, warehouse or greenhouse per unit time. The modular cultivation system further includes a mover robot for moving the growing module. The Vertical Farm relies on an ambulatory cultivation system and a cyclical automated operational protocol for planting, growing and harvesting made possible by the ambulatory growing module. Thus, access for crop planting, maintenance and harvesting is conveniently carried out through automation, that is, by commanding a specific ambulatory cultivation system to move autonomously to designated locations in the vertical farm.
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: March 26, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Joel L. Cuello, Yaser Mehdipour, Jack Welchert
  • Patent number: 11931239
    Abstract: Collapsible branched anastomosis devices allow for the formation of percutaneous vascular anastomoses using a Seldinger wire technique. This minimally invasive approach eliminates the need for a large surgical incision and also avoids the use of time consuming hand-suturing. The devices collapse to a fraction of their expanded volume and are configured to fit within a delivery sheath for over the wire delivery through a small incision in a blood vessel.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: March 19, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Charles T. Hennemeyer, Adam Gold