Patents Assigned to University of Cambridge
  • Patent number: 10909006
    Abstract: An apparatus comprises a main processor to execute a main stream of program instructions, two or more checker processors to execute respective checker streams of program instructions in parallel with each other, the checker streams corresponding to different portions of the main stream executed by the main processor, and error detection circuitry to detect an error when a mismatch is detected between an outcome of a given portion of the main stream executed on the main processor and an outcome of the corresponding checker stream executed on one of the plurality of checker processors. This approach enables high performance main processors 4 to be checked for errors with lower circuit area and power consumption overhead than a dual-core lockstep technique.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: February 2, 2021
    Assignees: Arm Limited, The Chancellor, Masters and Scholars of the University of Cambridge
    Inventors: Sam Ainsworth, Thomas Christopher Grocutt, Timothy Martin Jones
  • Patent number: 10831494
    Abstract: A main processor 4 executes a main program and has an associated cache memory 6. Event detection circuitry 12 detects events consequent upon execution of the main program and indicative of data to be used by the main processor. One or more programmable further processors 16, 18 is triggered to execute a further program by the events detected by the event detection circuitry 12. Prefetch circuitry 28 is responsive to the further program executed by the one or more programmable further processors to trigger prefetching of the data to be used by the main processor to the cache memory.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: November 10, 2020
    Assignees: ARM Limited, The Chancellor, Masters and Scholars of the University of Cambridge
    Inventors: Thomas Christopher Grocutt, Sam Ainsworth, Timothy Martin Jones
  • Publication number: 20200320987
    Abstract: A speech processing system includes an input for receiving an input utterance spoken by a user and a word alignment unit configured to align different sequences of acoustic speech models with the input utterance spoken by the user. Each different sequence of acoustic speech models corresponds to a different possible utterance that a user might make. The system identifies any parts of a read prompt text that the user skipped; any parts of the read prompt text that the user repeated; and any speech sounds that the user inserted between words of the read prompt text. The information from the word alignment unit can be used to assess the proficiency and/or fluency of the user's speech.
    Type: Application
    Filed: June 19, 2020
    Publication date: October 8, 2020
    Applicant: THE CHANCELLOR, MASTERS, AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
    Inventors: Thomas William John ASH, Anthony John ROBINSON
  • Patent number: 10783880
    Abstract: A speech processing system includes an input for receiving an input utterance spoken by a user and a word alignment unit configured to align different sequences of acoustic speech models with the input utterance spoken by the user. Each different sequence of acoustic speech models corresponds to a different possible utterance that a user might make. The system identifies any parts of a read prompt text that the user skipped; any parts of the read prompt text that the user repeated; and any speech sounds that the user inserted between words of the read prompt text. The information from the word alignment unit can be used to assess the proficiency and/or fluency of the user's speech.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: September 22, 2020
    Assignee: THE CHANCELLOR, MASTERS, AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
    Inventors: Thomas William John Ash, Anthony John Robinson
  • Patent number: 10730862
    Abstract: The present invention relates to bifunctional compounds, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins that are degraded and/or otherwise inhibited by bifunctional compounds of the present invention. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand that binds to the ubiquitin ligase and on the other end a moiety that binds a target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. The present invention exhibits a broad range of pharmacological activities associated with compounds of the present invention, consistent with the degradation/inhibition of targeted polypeptides.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: August 4, 2020
    Assignees: Yale University, Glaxosmithkline Intellectual Property Development, Cambridge Enterprise Limited University of Cambridge
    Inventors: Craig M. Crews, Dennis Buckley, Alessio Ciulli, William Jorgensen, Peter C. Gareiss, Inge Van Molle, Jeffrey Gustafson, Hyun-Seop Tae, Julien Michel, Denton Wade Hoyer, Anke G. Roth, John David Harling, Ian Edward David Smith, Afjal Hussain Miah, Sebastien Andre Campos, Joelle Le
  • Patent number: 10679642
    Abstract: A signal processing apparatus and method are provided for separating a plurality of mixture signals from a MIMO system to iteratively obtain a plurality of output signals. The plurality of mixture signals are a response of the MIMO system to a plurality of source signals. The signal processing apparatus comprises a plurality of blind source separators including a first blind source separator based on a first blind source separation technique or algorithm and a second blind source separator based on a second blind source separation technique or algorithm, wherein the first blind source separator is configured to compute a first plurality of preliminary output signals on the basis of a first set of coefficients describing the MIMO system and wherein the second blind source separator is configured to compute a second plurality of preliminary output signals on the basis of a second set of coefficients describing the MIMO system.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: June 9, 2020
    Assignees: Huawei Technologies Co., Ltd., University of Cambridge
    Inventors: Milos Markovic, Karim Helwani, Herbert Buchner, Simon Godsill
  • Patent number: 9752970
    Abstract: A method of testing the oxidation resistance of an alloy includes applying a layer of salt on the alloy's surface and placing the alloy in a furnace at a temperature of at least 1000° C. and containing an oxygen containing gas. The alloy is maintained in the furnace at the predetermined temperature for a period of time then the alloy is removed from the furnace and the alloy is to cool to ambient temperature or other suitable temperature. These steps are repeated for a number of times to maintain the salt on the alloy's surface at a level of 0.5 to 30 ?g cm?2 h?1. The alloy is weighed periodically to determine oxidation resistance. The addition of salt reduces the time to test the oxidation resistance of the alloy and the addition of the salt mimics the degradation of the alloy in a real working environment in a gas turbine engine.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: September 5, 2017
    Assignees: ROLLS-ROYCE PLC, THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
    Inventors: Stephen Moray Bagnall, Julian Charles Mason-Flucke, Catherine Mary Fiona Rae, Siavash Pahlavanyali
  • Patent number: 9679256
    Abstract: Embodiments herein provide automated assessment of examination scripts, such as English for Speakers of Other Languages (ESOL) examination scripts, written in response to prompts eliciting free text answers. In an embodiment, the task may be defined as discriminative preference ranking. Further, a system employing such methodology may be trained and tested on a corpus of manually-graded scripts. Embodiments herein, unlike extant solutions, are relatively prompt-insensitive and resistant to subversion, even if the operating principles are known. Embodiments may also detect scripts which are linguistically good but non-responsive to prompts such as memorized responses.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: June 13, 2017
    Assignee: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
    Inventors: Ted Briscoe, Ben Medlock, Oeistein Andersen
  • Publication number: 20160131918
    Abstract: Embodiments of the present disclosure provide a stereoscopic imaging apparatus and method, and a display. The stereoscopic imaging apparatus includes: a display panel, which includes multiple pixel units, and is configured to display images in a time division multiplexing scheme; and an electro-optic modulation layer, which includes multiple electro-optic modulation units respectively arranged at positions corresponding to the multiple pixel units, and is configured to alternately deflect light rays of the images displayed on the multiple pixel units into different projection directions under the effect of electric fields that change in a time division multiplexing scheme, where the electric fields that change in a time division multiplexing scheme change synchronously with the images displayed in a time division multiplexing scheme. The technical solutions of the embodiments of the present disclosure can improve resolution of auto-stereoscopic display.
    Type: Application
    Filed: January 18, 2016
    Publication date: May 12, 2016
    Applicants: HUAWEI TECHNOLOGIES CO.,LTD., UNIVERSITY OF CAMBRIDGE
    Inventors: Daping Chu, Brian Robertson, Jiong Zhou, Jun Yao
  • Patent number: 9274400
    Abstract: The invention relates to optical beam steering. There is described an optical beam steering apparatus, comprising: a splitter arranged to split an optical beam into at least a first part having a first polarization and a second part having a second polarization, said first and second polarizations being substantially mutually orthogonal; a first liquid crystal device region arranged to receive said first part and to have director orientation substantially aligned to said first polarization; and a second liquid crystal device region arranged to receive said second part and to have director orientation substantially aligned to said second polarization.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: March 1, 2016
    Assignee: Cambridge Enterprise Limited, University of Cambridge
    Inventors: Neil Collings, William Crossland, Maura Michelle Redmond, John Richard Moore, David Nugent, Brian Robertson
  • Publication number: 20150354010
    Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.
    Type: Application
    Filed: June 12, 2015
    Publication date: December 10, 2015
    Applicants: Perlegen Sciences, Inc., University of Cambridge
    Inventors: David Cox, Dennis Ballinger, Bruce Ponder, Doug Easton
  • Publication number: 20150168409
    Abstract: Some embodiments are related to a method for determining if a subject has an increased likelihood of high grade dysplasia (HGD) or esophagal adenocarcinoma (EC). An exemplary method can include providing a sample from an AFI patch of the subject's esophagus, assaying the sample for (i) aneuploidy, and (ii) abnormal p53, and (iii) abnormal Cyclin A, wherein if the sample shows the presence of at least two of (i), (ii) and (iii), then the subject is determined as having an increased likelihood of high grade dysplasia (HGD) or esophagal adenocarcinoma (EC). The invention also relates to certain methods of medical treatment.
    Type: Application
    Filed: May 17, 2013
    Publication date: June 18, 2015
    Applicants: The University of Cambridge, Medical Research Council
    Inventors: Massimiliano Di Pietro, Rebecca Fitzgerald, Xinxue Liu
  • Patent number: 8432030
    Abstract: A power electronic package includes: first and second high thermal conductivity insulating non-planar substrates; and multiple semiconductor chips and electronic components between the substrates. Each substrate includes multiple electrical insulator layers and patterned electrical conductor layers connecting to the electronic components, and further includes multiple raised regions or posts, which are bonded together so that the substrates are mechanically and electrically connected. The number, arrangement, and shape of the raised regions or posts are adjusted to have mechanical separation between the substrates. The electrical conductor layers are separated and isolated one another so that multiple electric circuits are provided on at least one of the substrates.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: April 30, 2013
    Assignees: DENSO CORPORATION, University of Cambridge, The University of Sheffield
    Inventors: Rajesh Kumar Malhan, C Mark Johnson, Cyril Buttay, Jeremy Rashid, Florin Udrea
  • Patent number: 8274086
    Abstract: A wide band gap semiconductor device has a transistor cell region, a diode forming region, an electric field relaxation region located between the transistor cell region and the diode forming region, and an outer peripheral region surrounding the transistor cell region and the diode forming region. In the transistor cell region, a junction field effect transistor is disposed. In the diode forming region, a diode is disposed. In the electric field relaxation region, an isolating part is provided. The isolating part includes a trench dividing the transistor cell region and the diode forming region, a first conductivity-type layer disposed on an inner wall of the trench, and a second conductivity-type layer disposed on a surface of the first conductivity-type layer so as to fill the trench. The first conductivity-type layer and the second conductivity-type layer provide a PN junction.
    Type: Grant
    Filed: July 28, 2009
    Date of Patent: September 25, 2012
    Assignees: DENSO CORPORATION, University of Cambridge
    Inventors: Rajesh Kumar Malhan, Yuuichi Takeuchi, Jeremy Rashid
  • Publication number: 20110254177
    Abstract: A power electronic package includes: first and second high thermal conductivity insulating non-planar substrates; and multiple semiconductor chips and electronic components between the substrates. Each substrate includes multiple electrical insulator layers and patterned electrical conductor layers connecting to the electronic components, and further includes multiple raised regions or posts, which are bonded together so that the substrates are mechanically and electrically connected. The number, arrangement, and shape of the raised regions or posts are adjusted to have mechanical separation between the substrates. The electrical conductor layers are separated and isolated one another so that multiple electric circuits are provided on at least one of the substrates.
    Type: Application
    Filed: June 29, 2011
    Publication date: October 20, 2011
    Applicants: DENSO CORPORATION, The University of Sheffield, University of Cambridge
    Inventors: Rajesh Kumar MALHAN, C Mark JOHNSON, Cyril BUTTAY, Jeremy RASHID, Florin UDREA
  • Patent number: 7999369
    Abstract: A power electronic package includes: first and second high thermal conductivity insulating non-planar substrates; and multiple semiconductor chips and electronic components between the substrates. Each substrate includes multiple electrical insulator layers and patterned electrical conductor layers connecting to the electronic components, and further includes multiple raised regions or posts, which are bonded together so that the substrates are mechanically and electrically connected. The number, arrangement, and shape of the raised regions or posts are adjusted to have mechanical separation between the substrates. The electrical conductor layers are separated and isolated one another so that multiple electric circuits are provided on at least one of the substrates.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: August 16, 2011
    Assignees: DENSO CORPORATION, University of Cambridge, The University of Sheffield
    Inventors: Rajesh Kumar Malhan, C. Mark Johnson, Cyril Buttay, Jeremy Rashid, Florin Udrea
  • Publication number: 20100025693
    Abstract: A wide band gap semiconductor device has a transistor cell region, a diode forming region, an electric field relaxation region located between the transistor cell region and the diode forming region, and an outer peripheral region surrounding the transistor cell region and the diode forming region. In the transistor cell region, a junction field effect transistor is disposed. In the diode forming region, a diode is disposed. In the electric field relaxation region, an isolating part is provided. The isolating part includes a trench dividing the transistor cell region and the diode forming region, a first conductivity-type layer disposed on an inner wall of the trench, and a second conductivity-type layer disposed on a surface of the first conductivity-type layer so as to fill the trench. The first conductivity-type layer and the second conductivity-type layer provide a PN junction.
    Type: Application
    Filed: July 28, 2009
    Publication date: February 4, 2010
    Applicants: DENSO CORPORATION, University of Cambridge
    Inventors: Rajesh Kumar Malhan, Yuuichi Takeuchi, Jeremy Rashid
  • Publication number: 20090239226
    Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.
    Type: Application
    Filed: February 13, 2009
    Publication date: September 24, 2009
    Applicants: PERLEGEN SCIENCES, INC., UNIVERSITY OF CAMBRIDGE
    Inventors: David Cox, Dennis Ballinger, Bruce Ponder, Doug Easton
  • Publication number: 20090239763
    Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.
    Type: Application
    Filed: February 13, 2009
    Publication date: September 24, 2009
    Applicants: PERLEGEN SCIENCES, INC., UNIVERSITY OF CAMBRIDGE
    Inventors: David Cox, Dennis Ballinger, Bruce Ponder, Doug Easton
  • Publication number: 20090208962
    Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.
    Type: Application
    Filed: February 13, 2009
    Publication date: August 20, 2009
    Applicants: PERLEGEN SCIENCES, INC., UNIVERSITY OF CAMBRIDGE
    Inventors: DAVID COX, DENNIS BALLINGER, BRUCE PONDER, DOUG EASTON