Abstract: An apparatus comprises a main processor to execute a main stream of program instructions, two or more checker processors to execute respective checker streams of program instructions in parallel with each other, the checker streams corresponding to different portions of the main stream executed by the main processor, and error detection circuitry to detect an error when a mismatch is detected between an outcome of a given portion of the main stream executed on the main processor and an outcome of the corresponding checker stream executed on one of the plurality of checker processors. This approach enables high performance main processors 4 to be checked for errors with lower circuit area and power consumption overhead than a dual-core lockstep technique.

Abstract: A main processor 4 executes a main program and has an associated cache memory 6. Event detection circuitry 12 detects events consequent upon execution of the main program and indicative of data to be used by the main processor. One or more programmable further processors 16, 18 is triggered to execute a further program by the events detected by the event detection circuitry 12. Prefetch circuitry 28 is responsive to the further program executed by the one or more programmable further processors to trigger prefetching of the data to be used by the main processor to the cache memory.

Abstract: A speech processing system includes an input for receiving an input utterance spoken by a user and a word alignment unit configured to align different sequences of acoustic speech models with the input utterance spoken by the user. Each different sequence of acoustic speech models corresponds to a different possible utterance that a user might make. The system identifies any parts of a read prompt text that the user skipped; any parts of the read prompt text that the user repeated; and any speech sounds that the user inserted between words of the read prompt text. The information from the word alignment unit can be used to assess the proficiency and/or fluency of the user's speech.

Abstract: A speech processing system includes an input for receiving an input utterance spoken by a user and a word alignment unit configured to align different sequences of acoustic speech models with the input utterance spoken by the user. Each different sequence of acoustic speech models corresponds to a different possible utterance that a user might make. The system identifies any parts of a read prompt text that the user skipped; any parts of the read prompt text that the user repeated; and any speech sounds that the user inserted between words of the read prompt text. The information from the word alignment unit can be used to assess the proficiency and/or fluency of the user's speech.

Abstract: The present invention relates to bifunctional compounds, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins that are degraded and/or otherwise inhibited by bifunctional compounds of the present invention. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand that binds to the ubiquitin ligase and on the other end a moiety that binds a target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. The present invention exhibits a broad range of pharmacological activities associated with compounds of the present invention, consistent with the degradation/inhibition of targeted polypeptides.

Abstract: A signal processing apparatus and method are provided for separating a plurality of mixture signals from a MIMO system to iteratively obtain a plurality of output signals. The plurality of mixture signals are a response of the MIMO system to a plurality of source signals. The signal processing apparatus comprises a plurality of blind source separators including a first blind source separator based on a first blind source separation technique or algorithm and a second blind source separator based on a second blind source separation technique or algorithm, wherein the first blind source separator is configured to compute a first plurality of preliminary output signals on the basis of a first set of coefficients describing the MIMO system and wherein the second blind source separator is configured to compute a second plurality of preliminary output signals on the basis of a second set of coefficients describing the MIMO system.

Abstract: A method of testing the oxidation resistance of an alloy includes applying a layer of salt on the alloy's surface and placing the alloy in a furnace at a temperature of at least 1000° C. and containing an oxygen containing gas. The alloy is maintained in the furnace at the predetermined temperature for a period of time then the alloy is removed from the furnace and the alloy is to cool to ambient temperature or other suitable temperature. These steps are repeated for a number of times to maintain the salt on the alloy's surface at a level of 0.5 to 30 ?g cm?2 h?1. The alloy is weighed periodically to determine oxidation resistance. The addition of salt reduces the time to test the oxidation resistance of the alloy and the addition of the salt mimics the degradation of the alloy in a real working environment in a gas turbine engine.

Abstract: Embodiments herein provide automated assessment of examination scripts, such as English for Speakers of Other Languages (ESOL) examination scripts, written in response to prompts eliciting free text answers. In an embodiment, the task may be defined as discriminative preference ranking. Further, a system employing such methodology may be trained and tested on a corpus of manually-graded scripts. Embodiments herein, unlike extant solutions, are relatively prompt-insensitive and resistant to subversion, even if the operating principles are known. Embodiments may also detect scripts which are linguistically good but non-responsive to prompts such as memorized responses.

Abstract: Embodiments of the present disclosure provide a stereoscopic imaging apparatus and method, and a display. The stereoscopic imaging apparatus includes: a display panel, which includes multiple pixel units, and is configured to display images in a time division multiplexing scheme; and an electro-optic modulation layer, which includes multiple electro-optic modulation units respectively arranged at positions corresponding to the multiple pixel units, and is configured to alternately deflect light rays of the images displayed on the multiple pixel units into different projection directions under the effect of electric fields that change in a time division multiplexing scheme, where the electric fields that change in a time division multiplexing scheme change synchronously with the images displayed in a time division multiplexing scheme. The technical solutions of the embodiments of the present disclosure can improve resolution of auto-stereoscopic display.

Abstract: The invention relates to optical beam steering. There is described an optical beam steering apparatus, comprising: a splitter arranged to split an optical beam into at least a first part having a first polarization and a second part having a second polarization, said first and second polarizations being substantially mutually orthogonal; a first liquid crystal device region arranged to receive said first part and to have director orientation substantially aligned to said first polarization; and a second liquid crystal device region arranged to receive said second part and to have director orientation substantially aligned to said second polarization.

Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.

Abstract: Some embodiments are related to a method for determining if a subject has an increased likelihood of high grade dysplasia (HGD) or esophagal adenocarcinoma (EC). An exemplary method can include providing a sample from an AFI patch of the subject's esophagus, assaying the sample for (i) aneuploidy, and (ii) abnormal p53, and (iii) abnormal Cyclin A, wherein if the sample shows the presence of at least two of (i), (ii) and (iii), then the subject is determined as having an increased likelihood of high grade dysplasia (HGD) or esophagal adenocarcinoma (EC). The invention also relates to certain methods of medical treatment.

Abstract: A power electronic package includes: first and second high thermal conductivity insulating non-planar substrates; and multiple semiconductor chips and electronic components between the substrates. Each substrate includes multiple electrical insulator layers and patterned electrical conductor layers connecting to the electronic components, and further includes multiple raised regions or posts, which are bonded together so that the substrates are mechanically and electrically connected. The number, arrangement, and shape of the raised regions or posts are adjusted to have mechanical separation between the substrates. The electrical conductor layers are separated and isolated one another so that multiple electric circuits are provided on at least one of the substrates.

Abstract: A wide band gap semiconductor device has a transistor cell region, a diode forming region, an electric field relaxation region located between the transistor cell region and the diode forming region, and an outer peripheral region surrounding the transistor cell region and the diode forming region. In the transistor cell region, a junction field effect transistor is disposed. In the diode forming region, a diode is disposed. In the electric field relaxation region, an isolating part is provided. The isolating part includes a trench dividing the transistor cell region and the diode forming region, a first conductivity-type layer disposed on an inner wall of the trench, and a second conductivity-type layer disposed on a surface of the first conductivity-type layer so as to fill the trench. The first conductivity-type layer and the second conductivity-type layer provide a PN junction.

Abstract: A power electronic package includes: first and second high thermal conductivity insulating non-planar substrates; and multiple semiconductor chips and electronic components between the substrates. Each substrate includes multiple electrical insulator layers and patterned electrical conductor layers connecting to the electronic components, and further includes multiple raised regions or posts, which are bonded together so that the substrates are mechanically and electrically connected. The number, arrangement, and shape of the raised regions or posts are adjusted to have mechanical separation between the substrates. The electrical conductor layers are separated and isolated one another so that multiple electric circuits are provided on at least one of the substrates.

Abstract: A power electronic package includes: first and second high thermal conductivity insulating non-planar substrates; and multiple semiconductor chips and electronic components between the substrates. Each substrate includes multiple electrical insulator layers and patterned electrical conductor layers connecting to the electronic components, and further includes multiple raised regions or posts, which are bonded together so that the substrates are mechanically and electrically connected. The number, arrangement, and shape of the raised regions or posts are adjusted to have mechanical separation between the substrates. The electrical conductor layers are separated and isolated one another so that multiple electric circuits are provided on at least one of the substrates.

Abstract: A wide band gap semiconductor device has a transistor cell region, a diode forming region, an electric field relaxation region located between the transistor cell region and the diode forming region, and an outer peripheral region surrounding the transistor cell region and the diode forming region. In the transistor cell region, a junction field effect transistor is disposed. In the diode forming region, a diode is disposed. In the electric field relaxation region, an isolating part is provided. The isolating part includes a trench dividing the transistor cell region and the diode forming region, a first conductivity-type layer disposed on an inner wall of the trench, and a second conductivity-type layer disposed on a surface of the first conductivity-type layer so as to fill the trench. The first conductivity-type layer and the second conductivity-type layer provide a PN junction.

Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.

Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.

Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.