Patents Assigned to University of Central Florida Research Foundation, Inc.
  • Patent number: 11231570
    Abstract: A fluorescent emission HIST microscope utilizes a highly inclined tile beam that is scanned over a biological sample object. Fluorescence emission from the sample is propagated through a confocal slit into an sCMOS camera supporting a rolling shutter mode. The tile beam is synchronously swept with the readout of the camera to facilitate the rejection of background. The system provides for decoupling of the total imaging area from the beam thickness, which now solely depends on the width of the tile beam, enabling a thinner illumination and larger FOV imaging. Clear visualization of single molecules across a 130 ?m×130 ?m FOV provided a greater than 40× FOV than conventional HILO imaging. An associated imaging method is disclosed.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: January 25, 2022
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Kyu Young Han, Jialei Tang
  • Patent number: 11229608
    Abstract: Compositions and methods for systemic delivery of at least one cargo in a vascular plant. Compositions may include at least one cargo delivery particle, having a core and a shell; and at least one cargo disposed on the shell. The core may include at least one micronutrient. The shell may include a coating material. The at least one cargo delivery particle may have a size of less than about 10 nanometers. Methods may include administering an effective amount of the compositions to a plant.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: January 25, 2022
    Assignees: University of Central Florida Research Foundation, Inc., ICAR-Central Citrus Research Institute, Indian Institute Technology ROORKEE
    Inventors: Swadeshmukul Santra, Ali Ozcan, Dilip K. Ghosh, Sunil Kokane, Pranav Kumar, Ashwani Kumar Sharma
  • Patent number: 11230569
    Abstract: Novel compositions and methods for the treatment and prevention of malaria are disclosed herein.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: January 25, 2022
    Assignees: University of Central Florida Research Foundation, Inc., The Board of Regents of The University of Oklahoma
    Inventors: Debopam Chakrabarti, Robert H. Cichewicz, Shengxin Cai, Jin Woo Lee, Jennifer E. Collins
  • Patent number: 11223179
    Abstract: A laser system may include a seed laser formed from a Ti:Sapphire laser providing pulsed light and an optical parametric amplifier to generate pulsed light within a Holmium emission spectrum as seed pulses in response to the pulsed light from the Ti:Sapphire laser. A laser system may further include an amplifier to generate amplified pulses of light in response to the seed pulses from the seed laser, where the amplified pulses include at least some of the seed pulses amplified by the one or more Holmium-doped gain media pumped by the one or more pump lasers. The amplifier may include one or more Holmium-doped gain media and one or more pump lasers providing continuous-wave pump light within an absorption spectrum of the one or more Holmium-doped gain media.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: January 11, 2022
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Krishna Murari, Yanchun Yin, Fangjie Zhou, Yi Wu, Zenghu Chang
  • Patent number: 11221205
    Abstract: A non-destructive iterative interferometric tomographic technique for imaging and reconstruction of phase objects as well as objects with complex permittivity and, particularly, to iterative optical diffraction tomographic (iODT) imaging and reconstruction of phase objects with high refractive index (RI) contrast, complex structures, and/or large optical path differences (OPDs) against the background, which cause multiple scattering, and applications thereof.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: January 11, 2022
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Guifang Li, Shengli Fan, Seth Smith-Dryden, Bahaa Saleh
  • Patent number: 11217738
    Abstract: Various methods and devices for ultrasensitive infrared photodetection, infrared imaging, and other optoelectronic applications using the plasmon assisted thermoelectric effect in graphene are described. Infrared detection by the photo-thermoelectric uses the generation of a temperature gradient (?T) for the efficient collection of the generated hot-carriers. An asymmetric plasmon-induced hot-carrier Seebeck photodetection scheme at room temperature exhibits a remarkable responsivity along with an ultrafast response in the technologically relevant 8-12 ?m band. This is achieved by engineering the asymmetric electronic environment of the generated hot carriers on chemical vapor deposition (CVD) grown large area nanopatterned monolayer graphene, which leads to a record ?T across the device terminals thereby enhancing the photo-thermoelectric voltage beyond the theoretical limit for graphene. The results provide a strategy for uncooled, tunable, multispectral infrared detection.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: January 4, 2022
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Debashis Chanda, Michael Leuenberger, Alireza Safaei, Sayan Chandra
  • Patent number: 11217960
    Abstract: A diamond Raman laser may include a diamond Raman oscillator (DRO) with a first diamond gain medium, a seed laser providing a seed beam at a seed wavelength, and a cavity configured to resonate at a first-Stokes wavelength, the first-Stokes wavelength corresponding to first-Stokes emission in diamond when pumped with the seed wavelength, and where the DRO outputs a first-Stokes beam at the first-Stokes wavelength. The diamond Raman laser may further include a diamond Raman amplifier (DRA) to amplify the first-Stokes beam and generate an amplified first-Stokes beam, where the DRA includes two or more diamond Raman amplification stages, each including one or more second diamond gain media, and one or more optical filters to filter light with a second-Stokes wavelength generated in at least one of the one or more second gain media.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: January 4, 2022
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Martin Richardson, Soumya Sarang, Patrick Roumayah, Nathan Bodnar
  • Patent number: 11215605
    Abstract: A method and apparatus for determining a presence of a microorganism in a sample is provided. The method includes storing electrophysiological and/or impedance signatures of a plurality of microorganisms in a memory of a processor. The method also includes obtaining a sample and generating an electrophysiological and/or impedance signature of the sample. The electrophysiological and/or impedance signature of the sample is compared with the electrophysiological and/or impedance signatures in the memory. A presence of one of the plurality of microorganisms in the sample is then identified based on a correlation between the electrophysiological and/or impedance signature of the sample and the electrophysiological and/or impedance signature of the one of the plurality of microorganisms. A method is also provided for determining a growth stage of a microorganism in a sample.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: January 4, 2022
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Parthiban Rajasekaran, Swaminathan Rajaraman
  • Patent number: 11217760
    Abstract: Techniques for growing, at least one of: (a) quantum dots and (b) nano-crystals, on a surface of a material are provided. One method comprises placing a precursor on the surface; adding an antisolvent to the precursor; and growing at least one of the quantum dots and the nanocrystals on the surface.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: January 4, 2022
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Jayan Thomas, Basudev Pradhan, Farzana Chowdhury
  • Publication number: 20210407820
    Abstract: A method for isolating at least one conductive via from a surrounding glass substrate is provided. A support layer is formed over at least one surface of the glass substrate. Thereafter, the glass substrate is removed. As a result, the at least one conductive via can be analyzed without interference from the glass substrate.
    Type: Application
    Filed: May 28, 2021
    Publication date: December 30, 2021
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: Omar Saad Ahmed, Tengfei Jiang
  • Publication number: 20210393289
    Abstract: A laparoscopic surgery support system can include a plurality of ports configured to receive a trocar therethrough and a plurality of arms connecting the plurality of ports together and configured to allow fixation of a relative position of the plurality of ports. For example, the plurality of ports can include three or more ports.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 23, 2021
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventor: Sang-Eun Song
  • Patent number: 11198637
    Abstract: Gradient refractive index (GRIN) materials can include multi-phase composites having substances with differing refractive indices disposed non-uniformly within one another. Particular glass composites having a gradient index of refraction can include: an amorphous phase, and a phase-separated region disposed non-uniformly within the amorphous phase. The glass composites include a mixture containing: GeZ2 and A2Z3 in a combined molar ratio of about 60% to about 95%, and CsX and PbZ in a combined molar ratio of about 5% to about 40%, where A is As, Sb or Ga, X is Cl, Br or I, and Z is S or Se. When A is As, the glass composites include PbZ in a molar ratio of about 15% or less. The amorphous phase and the phase-separated region have refractive indices that differ from one another. More particularly, A is Ga or As, X is Cl, and Z is Se.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: December 14, 2021
    Assignees: Lockheed Martin Corporation, University of Central Florida Research Foundation, Inc.
    Inventors: Clara Rivero Baleine, Kathleen Richardson, Charmayne Smith
  • Patent number: 11199498
    Abstract: A portable spectrometer system is disclosed for more reliable and convenient on-site drug testing. More particularly, but not by way of limitation, the presently disclosed and/or claimed inventive concept(s) relates to a portable spectrometer system having a test strip having a fluorescent indicator, a fluorimeter, and a mobile computing device capable of determining the identity of an unknown substance in the sample.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: December 14, 2021
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventor: Richard George Blair
  • Patent number: 11193174
    Abstract: Provided are methods of detecting cancer in a patient that involve analyzing DNA in extracellular vesicles. Detection may involve screening for an insert in a 3? UTR of NANOGP8 present in extracellular vesicles. A method involves (i) obtaining a biological sample containing extracellular vesicles from the patient; (ii) isolating the vesicles from the biological sample; (iii) detecting an amount of NANOG DNA in the vesicles; (iv) comparing the amount of NANOG DNA in the vesicles with vesicles in a non-cancer cell sample, wherein an increased level of NANOG DNA in the vesicles from the patient as compared to the non-cancer cell sample provides a positive indication of cancer in the patient.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: December 7, 2021
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Kiminobu Sugaya, Vaidya Manjusha
  • Publication number: 20210363670
    Abstract: A color-changing product includes a fabric. At least a portion of the fabric includes or is arranged using at least one of (i) a color-changing fiber or (ii) a color-changing yarn including the color-changing fiber. The color-changing fiber includes an electrically conductive core having a first tensile strength, a reinforcement core having a second tensile strength that is greater than the first tensile strength, and a coating disposed around and along the electrically conductive core and the reinforcement core. The coating includes a polymeric material having a color-changing pigment.
    Type: Application
    Filed: May 21, 2020
    Publication date: November 25, 2021
    Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Ayman Abouraddy, Joshua Kaufman, Morgan Monroe, Felix Tan
  • Publication number: 20210363669
    Abstract: A color-changing product includes a fabric. The fabric includes a first layer and a second layer. The first layer is arranged using at least one fiber. The at least one fiber includes (a) an electrically conductive core and (b) a coating disposed around and along the electrically conductive core. The second layer is printed onto the first layer. The second layer includes a foreground thermochromic pigment that is selectively activatable by providing an electrical current to the electrically conductive core of the at least one fiber to change at least one of a foreground color or a pattern of the second layer.
    Type: Application
    Filed: May 21, 2020
    Publication date: November 25, 2021
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: Ayman Abouraddy, Joshua Kaufman, Felix Tan, Morgan Monroe
  • Patent number: 11179436
    Abstract: In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: November 23, 2021
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Annette Khaled, Rebecca Boohaker, Michael Lee, Jesus Perez Figueroa
  • Patent number: 11180492
    Abstract: The present disclosure provides compounds of Formula (I?), Formula (II), and Formula (III). The compounds described herein may useful in treating and/or preventing protozoan infections in a subject in need thereof, treating and/or preventing trypanosomal infections (e.g., Trypanosoma cruzi (T. cruzi) or Trypanosoma brucei infections) and/or plasmodial infections in a subject in need thereof, treating and/or preventing diseases in a subject in need thereof (e.g., Chagas disease, malaria, and/or sleeping sickness), and may be useful in treating and/or preventing infectious diseases in a subject in need thereof. Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including a compound described herein.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: November 23, 2021
    Assignees: University of Central Florida Research Foundation, Inc., The Regents of the University of California, Memorial Sloan-Kettering Cancer Center, The Broad Institute, Inc.
    Inventors: Derek Shieh Tan, Corinne N. Foley, Gustavo Moura-Letts, James McKerrow, Sivaraman Dandapani, Rahul Edwankar, Alyssa Verano, Debopam Chakrabarti, Bracken Roberts
  • Patent number: 11177473
    Abstract: High-performance flexible batteries are promising energy storage devices for portable and wearable electronics. The major obstacle to develop flexible batteries is the shortage of flexible electrodes with excellent electrochemical performance. Another challenge is the limited progress in the flexible batteries beyond Li-ion because of safety concerns for the Li-based electrochemical system. Accordingly, a self-supported tin sulfide (SnS) porous film (PF) was fabricated as a flexible cathode material in Al-ion battery, which delivers a high specific capacity of 406 mAh/g. A capacity decay rate of 0.03% per cycle was achieved, indicating a good stability. The self-supported and flexible SnS film also shows an outstanding electrochemical performance and stability during dynamic and static bending tests. Microscopic images demonstrated that the porous structure of SnS is beneficial for minimizing the volume expansion during charge/discharge.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: November 16, 2021
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventor: Yang Yang
  • Patent number: 11162972
    Abstract: A microelectromechanical system (MEMS) sensor includes a substrate having a piezoelectric layer thereon; a MEMS piezoelectric resonator including a reference electrode on a first side of the piezoelectric layer, a first port (port 1) including a capacitor coupling electrode on a side of the piezoelectric layer opposite the first side, and a second port (port 2) for excitation signal coupling including another electrode on the side opposite the first side. The MEMS piezoelectric resonator has a natural resonant frequency. A variable capacitor on the substrate is positioned lateral to the MEMS piezoelectric resonator having a first and a second plate are connected to port 1. An antenna or an oscillator circuit is connected to port 2. Responsive to a physical parameter a capacitance of the variable capacitor changes which changes a frequency of the MEMS piezoelectric resonator relative to the natural resonant frequency to generate a frequency shift.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: November 2, 2021
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Reza Abdolvand, Hakhamanesh Mansoorzare