Patents Assigned to University of Chile
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Patent number: 8759065Abstract: Nucleic acid and corresponding amino acid sequences of a cold adapted subtilisin-like activity protein, insolated from antarctic marine origin, preferably from an Antarctic bacteria (Polaribacter sp) that can be used in a variety of industrial contexts and commercial purposes including laundry detergents, food processing, leather processing and skin care products. Nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the cold adapted subtilisin-like protein are also described.Type: GrantFiled: August 6, 2008Date of Patent: June 24, 2014Assignee: University of ChileInventors: Juan A. Asenjo, Barbara A. Andrews, Juan Pablo Acevedo, Fernando Reyes, Luis O. Burzio
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Patent number: 8679814Abstract: A method of preparing a cold adapted xylanase by use of recombinant DNA techniques. A nucleic acid and corresponding amino acid sequences of a cold adapted xylanase, isolated from antarctic marine origin, preferably from an Antarctic bacteria (Psychrobacter sp.) are provided. These can be used in a variety of industrial contexts and for a variety of commercial purposes including more complete hydrolysis of lignocellulosic biomass into simple sugars that can then be fermented to products, such as liquid fuels and chemical feedstocks. The enzymes are also useful in the production methods of other industries, such as the animal feed, baking, and paper industries.Type: GrantFiled: February 2, 2010Date of Patent: March 25, 2014Assignee: University of ChileInventors: Juan A. Asenjo, Barbara A. Andrews, Juan Pablo Acevedo, Loreto Parra, Luis O. Burzio
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Patent number: 8337829Abstract: The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines and cultures. The invention also concerns proliferation factors, and compositions containing the factors, which are capable of increasing the proliferation potential of any human or other animal cell in culture. The subject invention further pertains to a method for proliferating cells in culture by contacting cells with the proliferation factors. The proliferated cells can range in plasticity and can include, for example, blast cells, fertilized ova, non-fertilized gametes, embryonic stem cells, adult stem cells, precursor or progenitor cells, and highly specialized cells. Optionally, the cells can be induced to cease proliferation.Type: GrantFiled: October 6, 2011Date of Patent: December 25, 2012Assignees: University of South Florida, University of ChileInventors: Thomas B. Freeman, Pablo Caviedes, Raul Caviedes
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Publication number: 20120264191Abstract: Nucleic acid and corresponding amino acid sequences of a cold adapted subtilisin-like activity protein, insolated from antarctic marine origin, preferably from an Antarctic bacteria (Polar ibacter sp) that can be used in a variety of industrial contexts and commercial purposes including laundry detergents, food processing, leather processing and skin care products. Nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the cold adapted subtilisin-like protein are also described.Type: ApplicationFiled: August 6, 2008Publication date: October 18, 2012Applicant: UNIVERSITY OF CHILEInventors: Juan A. Asenjo, Barbara A. Andrews, Juan Pablo Acevedo, Fernando Reyes, Luis O. Burzio
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Publication number: 20120148540Abstract: The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines and cultures. The invention also concerns proliferation factors, and compositions containing the factors, which are capable of increasing the proliferation potential of any human or other animal cell in culture. The subject invention further pertains to a method for proliferating cells in culture by contacting cells with the proliferation factors. The proliferated cells can range in plasticity and can include, for example, blast cells, fertilized ova, non-fertilized gametes, embryonic stem cells, adult stem cells, precursor or progenitor cells, and highly specialized cells. Optionally, the cells can be induced to cease proliferation.Type: ApplicationFiled: October 6, 2011Publication date: June 14, 2012Applicants: UNIVERSITY OF CHILE, UNIVERSITY OF SOUTH FLORIDAInventors: THOMAS B. FREEMAN, Pablo Caviedes, Raul Caviedes, Paul R. Sanberg, Don F. Cameron
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Patent number: 8137662Abstract: The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines and cultures. The invention also concerns proliferation factors, and compositions containing the factors, which are capable of increasing the proliferation potential of any human or other animal cell in culture. The subject invention further pertains to a method for proliferating cells in culture by containing cells with the proliferation factors. The proliferated cells can range in plasticity and can include, for example, blast cells, fertilized ova, non-fertilized gametes, embryonic stem cells, adult stem cells, precursor or progenitor cells, and highly specialized cells. Optionally, the cells can be induced to cease proliferation.Type: GrantFiled: October 31, 2007Date of Patent: March 20, 2012Assignees: University of South Florida, University of ChileInventors: Thomas B. Freeman, Pablo Caviedes, Raul Caviedes
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Publication number: 20110287515Abstract: A method of preparing a cold adapted xylanase by use of recombinant DNA techniques. A nucleic acid and corresponding amino acid sequences of a cold adapted xylanase, isolated from antarctic marine origin, preferably from an Antarctic bacteria (Psychrobacter sp.) are provided. These can be used in a variety of industrial contexts and for a variety of commercial purposes including more complete hydrolysis of lignocellulosic biomass into simple sugars that can then be fermented to products, such as liquid fuels and chemical feedstocks. The enzymes are also useful in the production methods of other industries, such as the animal feed, baking, and paper industries.Type: ApplicationFiled: February 2, 2010Publication date: November 24, 2011Applicant: UNIVERSITY OF CHILEInventors: Juan A. Asenjo, Barbara A. Andrews, Juan Pablo Acevedo, Loreto Parra, Luis O. Burzio
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Patent number: 7617208Abstract: Methods and apparatus are described for mining user queries found within the access logs of a website and for relating this information to the website's overall usage, structure, and content. Such techniques may be used to discover valuable information to improve the quality of the website, allowing the website to become more intuitive and adequate for the needs of its users.Type: GrantFiled: September 12, 2006Date of Patent: November 10, 2009Assignees: Yahoo! Inc., University of ChileInventors: Ricardo Alberto Baeza-Yates, Barbara Poblete
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Patent number: 7416885Abstract: The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines and cultures. The invention also concerns proliferation factors, and compositions containing the factors, which are capable of increasing the proliferation potential of any human or other animal cell in culture. The subject invention further pertains to a method for proliferation cells in culture by contacting cells with the proliferation factors. The proliferated cells can range in plasticity and can include, for example, blast cells, fertilized ova, non-fertilized gametes, embryonic stem cells, adult stem cells, precursor or progenitor cells, and highly specialized cells. Optionally, the cells can be induced to cease proliferation.Type: GrantFiled: February 7, 2003Date of Patent: August 26, 2008Assignees: University of South Florida, University of ChileInventors: Thomas B. Freeman, Pablo Caviedes, Raul Caviedes
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Patent number: 7323333Abstract: The subject invention pertains to materials and methods for inhibiting process formation and extension by cells in culture. The subject invention further includes cultures of process-forming cells wherein formation and extension of processes have been inhibited. In another aspect, the subject invention concerns methods of transplantation using process-forming cells that have been cultured by the process-inhibiting methods of the invention.Type: GrantFiled: March 31, 2004Date of Patent: January 29, 2008Assignees: University of South Florida, University of ChileInventors: Pablo Caviedes, Raul Caviedes, Thomas B. Freeman, Juan A. Asenjo, Barbara A. Andrews, Dario SepĂșlveda, Christian Arriagada, Julio Salazar Rivera
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Protein and nucleic acid sequence encoding a KRILL-derived cold adapted trypsin-like activity enzyme
Patent number: 7202074Abstract: The present invention provides nucleic acid and corresponding amino acid sequences of two isoforms of cold adapted trypsin-like activity protein, insolated from antarctic marine origin, preferably from antarctic krill (Euphausia superba) that can be used in a variety of industrial contexts and commercial purposes including laundry detergents, food processing, drugs and skin care products. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the cold adapted trypsin-like protein.Type: GrantFiled: July 22, 2004Date of Patent: April 10, 2007Assignee: University of ChileInventors: Juan A. Asenjo, Barbara A. Andrews, Fernando Reyes, Mauricio Salamanca, Luis Burzio