Patents Assigned to University of Debrecen
  • STEREOSELECTIVE SYNTHESIS OF 9-CIS.13,14-DIHYDRORETINOIC ACID AND ITS ETHYL ESTERS
    Publication number: 20180170867
    Abstract: The retinoid X receptors (RXRs) are ligand-activated transcription factors heterodimerize with a number of nuclear hormone receptors, thereby controlling a variety of physiological processes. The invention relates to novel enantiomer compounds which are derivatives of dihydroretinoic acid, their stereoselective synthesis, to pharmaceutical compositions containing the same and to the use of same in the treatment of diseases.
    Type: Application
    Filed: May 9, 2016
    Publication date: June 21, 2018
    Applicant: University of Debrecen
    Inventors: Wojciech KREZEL, Ralph RÜHL, Angel R. DE LERA
  • Modified peptide toxins
    Patent number: 9062119
    Abstract: The invention relates to toxin peptides capable of selectively inhibiting a Kv1.3 potassium channel protein. The toxin peptides of the invention are modified anuroctonus scorpion toxin peptides.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: June 23, 2015
    Assignees: University of Debrecen, University of Szeged
    Inventors: Zoltan Varga, Gyorgy Panyi, Gabor Toth, Kinga Rakosi
  • MODIFIED PEPTIDE TOXINS
    Publication number: 20150087603
    Abstract: The invention relates to toxin peptides capable of selectively inhibiting a Kv1.3 potassium channel protein. The toxin peptides of the invention are modified anuroctonus scorpion toxin peptides.
    Type: Application
    Filed: October 29, 2012
    Publication date: March 26, 2015
    Applicants: UNIVERSITY OF SZEGED, UNIVERSITY OF DEBRECEN
    Inventors: Zoltan Varga, Gyorgy Panyi, Gabor Toth, Kinga Rakosi
  • Nanoparticles from chitosan
    Patent number: 7740883
    Abstract: Methods are disclosed for preparing crosslinked core and core-shell nanoparticle polymers from chitosan. The final products of the present invention may be used as detergents and as additives for pharmaceutical composition and for drug delivery, and DNA carrier system. The nanoparticles made from biopolymers of the present invention may also be used in controlled release, superabsorbent materials and biomaterials like enzyme immobilization.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: June 22, 2010
    Assignee: University of Debrecen
    Inventors: Janos Borbely, Magdolna Bodnar