Abstract: Methods of treating or preventing microbial infection in a subject in need of treatment by administering a therapeutically effective amount of ergothioneine, or functional analog, or prodrug, or salt thereof. Ergothioneine may be advantageously administered in conjunction with lactoferrin.

Abstract: Systems and methods are disclosed to detect and/or classify electrophysiological signals as motor events.

Abstract: A method for improving blood flow in a patient who has undergone a first heart valve replacement procedure followed by a second heart valve replacement procedure is disclosed. The method includes positioning a second prosthetic replacement valve to replace a primary prosthetic replacement valve within the patient, providing a laser fenestration system including a laser fiber, guiding the laser fiber through the patient's circulatory system to the second prosthetic replacement valve, performing a laser ablation process using the laser fiber to remove portions of a leaflet tissue between any stent structure of the primary prosthetic replacement valve, removing the laser fiber from the patient's circulatory system, and finalizing the second prosthetic valve replacement procedure. In embodiments, the method includes removing native leaflet tissue using laser ablation. In embodiments, a fenestration system for implementing the described method is disclosed.

Abstract: Methods, compounds, and compositions for inhibiting ice nucleation are disclosed. A method includes selecting a modified polyvinyl alcohol molecule based on at least one altered hydroxyl distance of the modified polyvinyl alcohol molecule and applying the modified polyvinyl alcohol molecule to water molecules to inhibit ice nucleation when subjected to freezing temperatures.

Abstract: The present disclosure relates to a composition that includes a film having a network of randomly aligned carbon nanotubes, where the carbon nanotubes have an average diameter between about 0.6 nm and about 2.0 nm and the carbon nanotubes form bundles having an average diameter between about 3 nm and about 50 nm. In addition, the composition is characterized by a power factor ?2? between 1 ?W/mK2 and about 3500 ?W/mK2 and by ZT=?2?T/k between about 0.02 and about 2.0 over a temperature range between about 100 K and about 500 K.

Abstract: Systems and method for providing chaperone activity to a protein-containing compound is disclosed. The method includes selecting a nucleic acid based on one or more of the nucleic acid's particular properties and a specific sequence of the nucleic acid and applying the nucleic acid to a compound comprising one or more proteins to provide chaperone activity to the compound.

Abstract: Methods and systems are disclosed for determining active and/or reactive power flows in a distribution line of a distribution network. The determined power flows may be linear in nature, and they may further be used to determine an overall network power flow for the distribution network. Further, the network power flow can be used to determine a voltage magnitude for any distribution bus in the distribution network. The methods and systems are capable of considering a plurality of sensitivity factors that may affect one or more distribution buses.

Abstract: A therapeutic system comprising a posture-mimicry robot comprising a head-assembly, a neck assembly, and a body assembly comprising a hemispherical bottom portion; and a base portion comprising three rotary actuators; wherein the posture-mimicry robot is configured to perform rotational movement in each of yaw, pitch, and roll axes to perform therapeutic interactive movements, gestures, and audio-visual cues.

Abstract: Methods and systems for evaluating economic viability of a proposed microgrid, including uncertain variables are disclosed. One or more candidate distributed energy resources can be selected for use within a proposed microgrid. An investment cost and an operation cost of the one or more candidate distributed energy resources can be determined. A cost of drawing power from a main power grid can be compared to a sum of the investment cost and the operation cost of the one or more candidate distributed energy resources. The proposed microgrid can be identified for installation when the sum of the investment cost and the operation cost is less than the cost of drawing power from the main power grid.

Abstract: Methods of treating or preventing microbial infection in a subject in need of treatment by administering a therapeutically effective amount of ergothioneine, or functional analog, or prodrug, or salt thereof. Ergothioneine may be advantageously administered in conjunction with lactoferrin.

Abstract: A method for optimizing a shape of a replacement valve leaflet, wherein the shape of the replacement valve leaflet is determined by defining variable parameters of the replacement valve leaflet. The variable parameters may comprise: a valve height; a leaflet coaptation height, a first set of two control points for a first B-spline plane of symmetry; and a second set of two control points for a second B-spline plane tangent to a frame of the valve. The method may further comprise creating iterations of potential shapes of the replacement valve leaflet by changing one or more of the variable parameters using modeling software. The method may also comprise calculating the maximum stresses or strains on each of the potential shapes.

Abstract: Various arrangements for identifying and grading cancer in tissue samples are presented. A digital image of a stained tissue sample may be acquired. A Shearlet transform may be performed on the digital image of the stained tissue sample. Shearlet coefficients may be calculated based on the performed Shearlet transform of the normalized digital RGB image of the stained tissue sample. A trained neural network may be applied to create a plurality of feature maps using the digital image and Shearlet coefficients, wherein the trained neural network was trained using a plurality of images and Shearlet coefficients of a plurality of digital images. A classifier may be applied to an output of the trained neural network to identify whether cancer is present in the stained tissue sample. A notification may be output that is indicative of a grade of detected cancer in the sample.

Abstract: A circulation control system for an aerial vehicle. The system comprises an air supply unit attached to the aerial vehicle configured to generate a specified amount of mass air flow; an air delivery system, the air supply unit and the air delivery system being connected via at least one tube that turns at least one right angle; a circulation control wing through which air from the air supply unit is delivered through the air delivery system, the circulation control wing comprising at least one plenum configured to blow the air out of a slot in a trailing edge of the wing, and at least one dual radius flap positioned behind the slot.

Abstract: A mobile self-leveling landing platform vehicle is disclosed that includes a landing surface and one or more wheel assemblies. Each wheel assembly includes a wheel, a control arm coupled with the wheel and the body of the landing platform vehicle, and an actuator coupled with the control arm and the body of the platform vehicle. Methods for self-leveling the landing platform vehicle are also disclosed.

Abstract: Systems and methods are disclosed to detect and/or classify electrophysiological signals as motor events.

Abstract: Full-cycle rapid scan (RS) electron paramagnetic resonance (EPR) can be performed without the instability of prior art methods and with a higher scan rate than traditional half-scan methods. In particular, a full scan is performed, but the constant RF driving B-field can be mathematically represented as two step functions, each corresponding to one half of a full scan cycle. This mathematical representation can be carried through the deconvolution such that two deconvolutions, one for the up cycle and one for the down cycle, can be performed. The solutions to these two deconvolutions can then be summed to give a single spectrum having a higher signal-to-noise ratio than half-cycle RS scans.

Abstract: A mobile self-leveling landing platform vehicle is disclosed that includes a landing surface and one or more wheel assemblies. Each wheel assembly includes a wheel, a control arm coupled with the wheel and the body of the landing platform vehicle, and an actuator coupled with the control arm and the body of the platform vehicle. Methods for self-leveling the landing platform vehicle are also disclosed.

Abstract: A method for estimating a pose of a first object in relation to a second object, the second object comprising a visual marker comprising a plurality of ellipses comprises capturing a video image of the visual marker with an image capture device on the first object, then pre-processing frames of the video image on a graphics processing unit. The method comprises detecting the visual marker by finding contours in the frames to identify the plurality of ellipses and determining that a pattern of the plurality of ellipses match a known pattern of the visual marker. Then the method comprises obtaining coordinates of two or more of the plurality of ellipses of the visual marker, estimating the pose of the first object in relation to the second object by inputting the coordinates of the plurality of ellipses into a pose estimation algorithm, and filtering results of the pose estimation algorithm.

Abstract: Various systems and methods for detecting electron spins using electron paramagnetic resonance are described. An excitation signal generator configured to generate an excitation signal of varying amplitude and phase as compared to a reference signal may be present. A crossed-loop resonator configured to isolate a detection signal produced by the excitation signal exciting an object with a magnetic field may also be present. Further, a detection device configured to detect electron spins of the object using the detection signal isolated by the crossed-loop resonator may be present.

Abstract: Embodiments of the invention are directed toward a crossed-loop electron paramagnetic resonance resonator comprising a first resonator having a first resonator axis; and a second resonator having a second resonator axis. The first resonator axis and the second resonator axis can be substantially perpendicular. Either or both the first resonator and the second resonator can be a ribbon resonator having a plurality of metallic ribbons formed in a loop. Each metallic ribbon can include a central axis. The plurality of metallic ribbons can be arranged parallel relative one to another.