Abstract: Disclosed are methods of making BMP-2 microparticles and methods of using the microparticles. These microparticles are prepared, for example, by mixing a solution containing BMP-2 with a second solution whose ionic concentration and pH results in the precipitation of the BMP-2.
Type:
Grant
Filed:
February 10, 2003
Date of Patent:
March 1, 2011
Assignees:
University of Erlangen-Nurnberg, Wyeth Inc.
Inventors:
Susan J. Sofia, Daniel Schwartz, Wolfgang Friess