Patents Assigned to University of Exeter
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Publication number: 20240032533Abstract: The invention relates to trialkyl sulfonium salts, compositions comprising the trialkyl sulfonium salts, agricultural compositions comprising such compositions, to the use of the trialkyl sulfonium salts and of the compositions as pesticide, preferably as fungicide, and to methods for controlling or combating pests and/or improving plant health by means of the trialkyl sulfonium salts and the compositions.Type: ApplicationFiled: October 1, 2021Publication date: February 1, 2024Applicants: HELM AG, UNIVERSITY OF EXETERInventors: Winfried NESS, Henrique RAMINHOS, Joerg STROOT, Johann Christian NIENDORF, Gero STEINBERG, Sarah GURR
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Publication number: 20230413811Abstract: The invention relates to a trialkyl sulfonium chloride, compositions comprising the trialkyl sulfonium chloride, agricultural compositions comprising such compositions and trialkyl sulfonium chloride, respectively, to the use of the trialkyl sulfonium chloride and of the compositions as a pesticide, preferably as a fungicide, and to methods for controlling or combating pests and/or improving plant health by means of the trialkyl sulfonium chloride and compositions.Type: ApplicationFiled: October 1, 2021Publication date: December 28, 2023Applicants: HELM AG, UNIVERSITY OF EXETERInventors: Winfried NESS, Henrique RAMINHOS, Joerg STROOT, Johann Christian NIENDORF, Gero STEINBERG, Sarah GURR
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Publication number: 20230332659Abstract: An elastomeric isolator is described comprising a layer of an elastomeric material, wherein the layer of elastomeric material is provided with a reinforcing material layer in the form of a graphene layer.Type: ApplicationFiled: February 26, 2021Publication date: October 19, 2023Applicant: UNIVERSITY OF EXETERInventors: Maria Rosaria MARSICO, Julián Mauricio Londono MONSALVE, Monica F. CRACIUN
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Patent number: 11684266Abstract: A probe comprising a body portion and a tip portion. The body portion comprises: a first mounting portion comprising a plurality of first carriers, each first carrier being arranged to support an elongate first waveguide, the first carriers being disposed in an equiangular arrangement around a longitudinal axis of the body portion; a plurality of first waveguides, each first waveguide being supported in a respective one of the plurality of first carriers; and a body end fitting at which first ends of the first waveguides are supported in the equiangular arrangement around the longitudinal axis of the body portion such that the first waveguides can transmit electromagnetic radiation signals from an energy source to the body end fitting and/or transmit electromagnetic radiation signals from the body end fitting to a receiver.Type: GrantFiled: March 15, 2018Date of Patent: June 27, 2023Assignees: The University of Bristol, The University of Exeter, Gloucestershire Hospitals NHS Foundation TrustInventors: Nicholas Stone, John Charles Clifford Day
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Patent number: 11567389Abstract: A display is described which comprises a plurality of pixels (12), wherein each pixel (12) comprises a plasmonic resonator (26) including first and second metallic material elements (16, 22) and incorporating a layer (18) of a phase change material, the plasmonic resonator (26) being arranged such that in one material state of the phase change material (18) the electric field coupling between the second metallic material element (22) and the phase change material layer (18) is strong and so strong absorption of selected wavelengths of the incident light occurs, whereas in another state of the phase change material (18) the electric field coupling between the metallic material elements (16, 22) and the phase change material layer (18), and between the first and second metallic material elements (16, 22) is weak and so re-radiation of incident light occurs, the pixel (12) being of high reflectance.Type: GrantFiled: August 24, 2018Date of Patent: January 31, 2023Assignee: University of ExeterInventors: Santiago Garcia-Cuevas Carrillo, Christopher David Wright
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Patent number: 11556312Abstract: A co-processor for performing a matrix multiplication of an input matrix with a data matrix in one step may be provided. The co-processor receives input signals for the input matrix as optical signals. A plurality of photonic memory elements is arranged at crossing points of an optical waveguide crossbar array. The plurality of memory elements is configured to store values of the data matrix. Input signals are connected to input lines of the optical waveguide crossbar array. Output lines of the optical waveguide crossbar array represent a dot-product between a respective column of the optical waveguide crossbar array and the received input signals, and values of elements of the input matrix to be multiplied with the data matrix correspond to light intensities received at input lines of the respective photonic memory elements. Additionally, different wavelengths are used for each column of the input matrix optical signals.Type: GrantFiled: July 10, 2020Date of Patent: January 17, 2023Assignees: International Business Machines Corporation, Oxford University Innovation Limited, University of Exeter, University of MuensterInventors: Abu Sebastian, Manuel Le Gallo-Bourdeau, Christopher David Wright, Nathan Youngblood, Harish Bhaskaran, Xuan Li, Wolfram Pernice, Johannes Feldmann
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Patent number: 11414379Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: February 16, 2021Date of Patent: August 16, 2022Assignees: UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH OF HIGHER EDUCATION, XIAMAN UNIVERSITY, UNIVERSITY OF EXETERInventors: Dandan Sun, Xianming Deng, Jinwei Zhang, Mohammad Iqbal Hossain Bhuiyan, Bradley J. Molyneaux
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Publication number: 20220174950Abstract: The invention provides an antifungal composition comprising an antifungal compound of formula R—S+(R?)2 or R—N+(R?)3 wherein R is C17-C32 straight chain or branched alkyl; and each R? is independently methyl, ethyl, propyl, isopropyl or butyl; and uses of said composition as antifungal agents.Type: ApplicationFiled: March 18, 2020Publication date: June 9, 2022Applicant: University of ExeterInventors: Gero Steinberg, Sarah Gurr, Mark Wood
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Patent number: 11339093Abstract: A reinforced concrete material is described comprising a cementitious material (22) in which graphene is substantially uniformly distributed. A method of production of concrete is also described comprising the steps of forming a substantially uniform suspension (20) of graphene with water, and mixing the suspension (20) with a cementitious material (22) to form a concrete material (28).Type: GrantFiled: March 12, 2019Date of Patent: May 24, 2022Assignee: UNIVERSITY OF EXETERInventors: Monica Craciun, Dimitar Dimov, Saverio Russo
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Publication number: 20220146426Abstract: A test apparatus is disclosed that has a housing containing a location at which a sample tray containing a plurality of sample wells can be located, a light box positioned to permit irradiation of the sample tray, and an imaging arrangement to permit imaging of the sample tray. The light box has a light source including a light guide in the form of a plate of a transparent material and a plurality of light emitting devices provided adjacent at least one edge of the plate where a surface of the plate is provided with a plurality of transmitting regions and light is transmitted from the plate.Type: ApplicationFiled: February 12, 2020Publication date: May 12, 2022Applicant: UNIVERSITY OF EXETERInventors: Robert BEARDMORE, Ivana BEARDMORE, Kai LONGSHAW, Carlos REDING
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Patent number: 11142568Abstract: The invention relates to antibodies to Aspergillus species and to methods of producing those antibodies. The invention also relates to the use of such antibodies in identifying the presence of the Aspergillus species and to methods of treating an infection with the Aspergillus species.Type: GrantFiled: July 22, 2019Date of Patent: October 12, 2021Assignee: THE UNIVERSITY OF EXETERInventor: Christopher Thornton
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Patent number: 10995061Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: September 30, 2019Date of Patent: May 4, 2021Assignees: United States Government as Represented by the Department of Veterans Affairs, The University of Pittsburgh—of the Commonwealth of Higher Education, Xiamen University, University of ExeterInventors: Dandan Sun, Xianming Deng, Jinwei Zhang, Mohammad Iqbal Hossain Bhuiyan, Bradley J. Molyneaux
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Patent number: 10610163Abstract: Assessing Susceptibility to Epilepsy and Epileptic Seizures A method and system adapted to assist with assessing susceptibility to epilepsy and/or epileptic seizures in a patient receives (202) patient brain data and generates (204) a network model from the received patient brain data. The system further generates (206) synthetic brain activity data in at least some of the nodes of the network model and computes (208) seizure frequency from the synthetic brain activity data by monitoring transitions from non-seizure states to seizures states in at least some of the nodes over time. The system further includes a device (104, 110) configured to use the seizure frequency to compute (210) a likelihood of susceptibility to epilepsy and/or epileptic seizures in the patient, and a device (104, 110) configured to compare (212) the computed likelihood with another likelihood of susceptibility to epilepsy and/or epileptic seizures in order to assess whether the likelihood has increased or decreased.Type: GrantFiled: June 5, 2013Date of Patent: April 7, 2020Assignees: UNIVERSITY OF EXETER, KINGS COLLEGE LONDONInventors: John Robert Terry, Mark Richardson, Oscar Benjamin
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Patent number: 10422947Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.Type: GrantFiled: October 19, 2018Date of Patent: September 24, 2019Assignees: President and Fellows of Harvard College, University of ExeterInventors: Joanna Aizenberg, Mathias Kolle, Peter Vukusic, Robert D. Howe
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Publication number: 20190227224Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.Type: ApplicationFiled: October 19, 2018Publication date: July 25, 2019Applicants: President and Fellows of Harvard College, University of ExeterInventors: Joanna AIZENBERG, Mathias KOLLE, Peter VUKUSIC, Robert D. HOWE
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Patent number: 10231985Abstract: The present invention relates to the field of medicine. It more particularly relates to the use of compounds for preventing and/or treating dyslipidemia in a subject, said dyslipidemia typically being linked to the excess presence in the biological membranes, including in the biological membranes of non-adipocyte cells, of fatty acids, in particular of saturated long-chain fatty acids, and/or of sterols. The invention also relates to compositions, in particular pharmaceutical compositions and food supplements or complements, comprising such compounds, and to the uses thereof for preventing and/or treating dyslipidemia. The compounds and compositions according to the invention can in particular be advantageously used for preventing and/or treating a pathological condition selected from metabolic syndrome and/or a symptom or abnormality characteristic of metabolic syndrome, preferably for preventing or treating type 2 diabetes mellitus or hepatic steatosis.Type: GrantFiled: October 8, 2014Date of Patent: March 19, 2019Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE POITIERS, UNIVERSITY OF EXETERInventors: Miroslava Spanova, Thierry Ferreira, Romain Clement, Shalinee Dhayal, Noël Morgan
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Patent number: 10174086Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID NO:3, the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.Type: GrantFiled: August 22, 2016Date of Patent: January 8, 2019Assignee: University of ExeterInventors: Richard W. Titball, Sergio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
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Patent number: 10149907Abstract: The invention relates to a combination comprising (i) a compound A comprising a mitochondrial targeting group linked to a group capable of releasing hydrogen sulfide or a pharmaceutically acceptable salt thereof or a prodrug thereof, an inhibitor of the thioredoxin antioxidant system or a pharmaceutically acceptable salt thereof or a prodrug thereof, and/or a nitroxide or a pharmaceutically acceptable salt thereof or a prodrug thereof; and (ii) a photosensitizer or photosensitizer precursor; for use in photodynamic therapy.Type: GrantFiled: February 7, 2018Date of Patent: December 11, 2018Assignee: University of ExeterInventors: Mark Elliott Wood, Paul Graham Winyard, Daniel Colin Jeremy Ferguson, Matthew Whiteman, Alison Curnow, Alexis Perry
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Patent number: 10146007Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.Type: GrantFiled: January 23, 2014Date of Patent: December 4, 2018Assignees: President and Fellows of Harvard College, University of ExeterInventors: Joanna Aizenberg, Mathias Kolle, Peter Vukusic, Robert D. Howe
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Patent number: 10132780Abstract: Device and method for detecting a defect in a workpiece with a broadband transducer (10), a driving circuit connected to the transducer to operate the transducer in a actuator mode, a signal output circuit connectable to operate in a sensor mode, a control for selectively connecting the transducer to the driving circuit or signal output circuit wherein the driving circuit includes at least a pair of oscillators for generating signals of at least frequencies F1 and F2 and a summer for summing the signals to provide a driving circuit for the transducer.Type: GrantFiled: June 30, 2014Date of Patent: November 20, 2018Assignee: UNIVERSITY OF EXETERInventor: Peter Robert Armitage