Patents Assigned to University of Exeter
  • Patent number: 11684266
    Abstract: A probe comprising a body portion and a tip portion. The body portion comprises: a first mounting portion comprising a plurality of first carriers, each first carrier being arranged to support an elongate first waveguide, the first carriers being disposed in an equiangular arrangement around a longitudinal axis of the body portion; a plurality of first waveguides, each first waveguide being supported in a respective one of the plurality of first carriers; and a body end fitting at which first ends of the first waveguides are supported in the equiangular arrangement around the longitudinal axis of the body portion such that the first waveguides can transmit electromagnetic radiation signals from an energy source to the body end fitting and/or transmit electromagnetic radiation signals from the body end fitting to a receiver.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: June 27, 2023
    Assignees: The University of Bristol, The University of Exeter, Gloucestershire Hospitals NHS Foundation Trust
    Inventors: Nicholas Stone, John Charles Clifford Day
  • Patent number: 11567389
    Abstract: A display is described which comprises a plurality of pixels (12), wherein each pixel (12) comprises a plasmonic resonator (26) including first and second metallic material elements (16, 22) and incorporating a layer (18) of a phase change material, the plasmonic resonator (26) being arranged such that in one material state of the phase change material (18) the electric field coupling between the second metallic material element (22) and the phase change material layer (18) is strong and so strong absorption of selected wavelengths of the incident light occurs, whereas in another state of the phase change material (18) the electric field coupling between the metallic material elements (16, 22) and the phase change material layer (18), and between the first and second metallic material elements (16, 22) is weak and so re-radiation of incident light occurs, the pixel (12) being of high reflectance.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: January 31, 2023
    Assignee: University of Exeter
    Inventors: Santiago Garcia-Cuevas Carrillo, Christopher David Wright
  • Patent number: 11556312
    Abstract: A co-processor for performing a matrix multiplication of an input matrix with a data matrix in one step may be provided. The co-processor receives input signals for the input matrix as optical signals. A plurality of photonic memory elements is arranged at crossing points of an optical waveguide crossbar array. The plurality of memory elements is configured to store values of the data matrix. Input signals are connected to input lines of the optical waveguide crossbar array. Output lines of the optical waveguide crossbar array represent a dot-product between a respective column of the optical waveguide crossbar array and the received input signals, and values of elements of the input matrix to be multiplied with the data matrix correspond to light intensities received at input lines of the respective photonic memory elements. Additionally, different wavelengths are used for each column of the input matrix optical signals.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: January 17, 2023
    Assignees: International Business Machines Corporation, Oxford University Innovation Limited, University of Exeter, University of Muenster
    Inventors: Abu Sebastian, Manuel Le Gallo-Bourdeau, Christopher David Wright, Nathan Youngblood, Harish Bhaskaran, Xuan Li, Wolfram Pernice, Johannes Feldmann
  • Publication number: 20220174950
    Abstract: The invention provides an antifungal composition comprising an antifungal compound of formula R—S+(R?)2 or R—N+(R?)3 wherein R is C17-C32 straight chain or branched alkyl; and each R? is independently methyl, ethyl, propyl, isopropyl or butyl; and uses of said composition as antifungal agents.
    Type: Application
    Filed: March 18, 2020
    Publication date: June 9, 2022
    Applicant: University of Exeter
    Inventors: Gero Steinberg, Sarah Gurr, Mark Wood
  • Patent number: 10995061
    Abstract: The present disclosure is concerned with N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)benzamide compounds that are capable of inhibiting SPAK kinase function, methods of treating hypoxic brain injuries due to, for example, ischemic stroke. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: May 4, 2021
    Assignees: United States Government as Represented by the Department of Veterans Affairs, The University of Pittsburgh—of the Commonwealth of Higher Education, Xiamen University, University of Exeter
    Inventors: Dandan Sun, Xianming Deng, Jinwei Zhang, Mohammad Iqbal Hossain Bhuiyan, Bradley J. Molyneaux
  • Patent number: 10422947
    Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: September 24, 2019
    Assignees: President and Fellows of Harvard College, University of Exeter
    Inventors: Joanna Aizenberg, Mathias Kolle, Peter Vukusic, Robert D. Howe
  • Publication number: 20190227224
    Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.
    Type: Application
    Filed: October 19, 2018
    Publication date: July 25, 2019
    Applicants: President and Fellows of Harvard College, University of Exeter
    Inventors: Joanna AIZENBERG, Mathias KOLLE, Peter VUKUSIC, Robert D. HOWE
  • Patent number: 10174086
    Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID NO:3, the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: January 8, 2019
    Assignee: University of Exeter
    Inventors: Richard W. Titball, Sergio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
  • Patent number: 10149907
    Abstract: The invention relates to a combination comprising (i) a compound A comprising a mitochondrial targeting group linked to a group capable of releasing hydrogen sulfide or a pharmaceutically acceptable salt thereof or a prodrug thereof, an inhibitor of the thioredoxin antioxidant system or a pharmaceutically acceptable salt thereof or a prodrug thereof, and/or a nitroxide or a pharmaceutically acceptable salt thereof or a prodrug thereof; and (ii) a photosensitizer or photosensitizer precursor; for use in photodynamic therapy.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: December 11, 2018
    Assignee: University of Exeter
    Inventors: Mark Elliott Wood, Paul Graham Winyard, Daniel Colin Jeremy Ferguson, Matthew Whiteman, Alison Curnow, Alexis Perry
  • Patent number: 10146007
    Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: December 4, 2018
    Assignees: President and Fellows of Harvard College, University of Exeter
    Inventors: Joanna Aizenberg, Mathias Kolle, Peter Vukusic, Robert D. Howe
  • Patent number: 10058100
    Abstract: The invention relates to a compound comprising a mitochondrial targeting group linked to group capable of releasing hydrogen sulfide, or a pharmaceutically acceptable salt thereof, for use in the treatment of the human or animal body by surgery or therapy. The invention also relates to the use of the compound in the treatment of a plant, and to certain forms of the compound.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: August 28, 2018
    Assignee: The University of Exeter
    Inventors: Mark Wood, Matthew Whiteman, Alexis Perry
  • Patent number: 10053772
    Abstract: Methods of producing a uniformly or substantially uniformly doped relatively large area multi-layered graphene element are described comprising the steps of placing the graphene element and a dopant under low pressure conditions, and holding the graphene element and dopant at an elevated temperature for a period of time while under the low pressure conditions. In one arrangement, openings are formed in a multi-layered graphene element of relatively large area prior to doping. In another arrangement, a relatively large area multi-layered graphene element formed by an epitaxial growth technique is used. The invention also relates to an element produced using the aforementioned techniques.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: August 21, 2018
    Assignee: University of Exeter
    Inventors: Saverio Russo, Monica Craciun, Thomas Hardisty Bointon
  • Patent number: 9919049
    Abstract: Compounds for use The invention relates to a combination comprising (i) a compound A comprising a mitochondrial targeting group linked to a group capable of releasing hydrogen sulfide or a pharmaceutically acceptable salt thereof or a prodrug thereof, an inhibitor of the thioredoxin antioxidant system or pharmaceutically acceptable salt thereof or a prodrug thereof, and/or a nitroxide or a pharmaceutically acceptable salt thereof or a prodrug thereof; and (ii) a photosensitizer or photosensitizer precursor; for use in photodynamic therapy.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: March 20, 2018
    Assignee: University of Exeter
    Inventors: Mark Elliott Wood, Paul Graham Winyard, Daniel Colin Jeremy Ferguson, Matthew Whiteman, Alison Curnow, Alexis Perry
  • Patent number: 9865369
    Abstract: The present invention relates to a transparent chemically functionalized graphene with high electrical conductivity and which is stable in air. It also relates to a method of manufacturing a conductive and transparent graphene-based material.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: January 9, 2018
    Assignee: University of Exeter
    Inventors: Saverio Russo, Monica Felicia Craciun
  • Patent number: 9720151
    Abstract: A structure for broadband light funneling comprises a two-dimensional periodic array of connected ultrasubwavelength apertures, each aperture comprising a large sub-aperture that aids in the coupling of the incoming incident light and a small sub-aperture that funnels a significant fraction of the incident light power. The structure possesses all the capabilities of prior extraordinary optical transmission platforms, yet operates nonresonantly on a distinctly different mechanism. The structure demonstrates efficient ultrabroadband funneling of optical power confined in an area as small as ˜(?/500)2, where optical fields are enhanced, thus exhibiting functional possibilities beyond resonant platforms.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: August 1, 2017
    Assignees: National Technology & Engineering Solutions of Sandia, LLC, University of Exeter
    Inventors: Ganapathi Subramanian Subramania, Igal Brener, Stavroula Foteinopoulou
  • Publication number: 20170051023
    Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID NO:3, the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.
    Type: Application
    Filed: August 22, 2016
    Publication date: February 23, 2017
    Applicant: University of Exeter
    Inventors: Richard W. Titball, Sergio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
  • Patent number: 9573981
    Abstract: There is provided an epsilon toxin epitope polypeptide comprising a sequence of at least 10 contiguous amino acids from SEQ ID NO:3, the sequence comprising a mutation of at least one tyrosine residue compared to the equivalent sequence in SEQ ID NO:3, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:5 and having reduced toxicity compared with the toxicity of SEQ ID NO:5. The polypeptide is useful in a method of vaccinating a subject against developing a disease caused by clostridium perfringens and/or caused by (or associated with the presence of) active epsilon toxin.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: February 21, 2017
    Assignee: University of Exeter
    Inventors: Richard W. Titball, Monika Bokori-Brown, Claire Naylor
  • Patent number: 9422343
    Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID NO:3, the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: August 23, 2016
    Assignee: University of Exeter
    Inventors: Richard W. Titball, Sérgio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
  • Publication number: 20160230273
    Abstract: Methods of producing a uniformly or substantially uniformly doped relatively large area multi-layered graphene element are described comprising the steps of placing the graphene element and a dopant under low pressure conditions, and holding the graphene element and dopant at an elevated temperature for a period of time whilst under the low pressure conditions. In one arrangement, openings are formed in a multi-layered graphene element of relatively large area prior to doping. In another arrangement, a relatively large area multi-layered graphene element formed by an epitaxial growth technique is used. The invention also relates to an element produced using the aforementioned techniques.
    Type: Application
    Filed: September 26, 2014
    Publication date: August 11, 2016
    Applicant: University of Exeter
    Inventors: Saverio Russo, Monica Craciun, Thomas Hardisty Bointon
  • Publication number: 20150364614
    Abstract: A detector is described comprising a first graphene element (12), the first graphene element (12) comprising a few layer graphene element functionally doped with a dopant material and to which at least one electrode is connected.
    Type: Application
    Filed: January 14, 2014
    Publication date: December 17, 2015
    Applicant: University of Exeter
    Inventors: Freddie Withers, Thomas H. Bointon, Monica F. Craciun, Saverio Russo, Steven Martins