Patents Assigned to University of Florida Research Foundation, Inc.
  • Patent number: 10614953
    Abstract: Various embodiments to mitigate the contamination of electroplated cobalt-platinum films on substrates are described. In one embodiment, a device includes a substrate, a titanium nitride diffusion barrier layer formed upon the substrate, a titanium layer formed upon the titanium nitride diffusion barrier layer, a platinum seed layer, and a cobalt-platinum magnetic layer formed upon the platinum seed layer. Based in part on the use of the titanium nitride diffusion barrier layer and/or the platinum seed layer, improvements in the interfaces between the layers can be achieved after annealing, with less delamination, and with substantial improvements in the magnetic properties of the cobalt-platinum magnetic layer. Further, the cobalt-platinum magnetic layer can be formed at a relatively thin thickness of hundreds of nanometers to a few microns while still maintaining good magnetic properties.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: April 7, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: David P. Arnold, Ololade D. Oniku
  • Patent number: 10614358
    Abstract: Disclosed are various embodiments of memristive networks comprising a number of nodes. Memristive nanofibers are used to form conductive and memristive paths in the networks. Each memristive nanofiber may couple one or more nodes to one or more other nodes. In one case, a memristive network includes a first node, a second node, and a memristive fiber that couples the first node to the neural node. The memristive fiber comprises a conductive core and a memristive shell, where the conductive core forms a conductive path between the first node and the second node and the memristive shell forms a memristive path between the first node and the second node.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: April 7, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Juan Claudio Nino, Jack Kendall
  • Patent number: 10608660
    Abstract: Various examples of devices, methods and systems related to pulse based arithmetic units. In one example, a pulse domain device includes an augend area calculator to provide an augend area output for an augend pulse train; an addend area calculator to provide an addend area output for an addend pulse train; a resultant sum area (RSA) decoder to provide a RSA output using the augend and addend area outputs; and a pulse timing calculator to provide RSA output pulse timing. In another example, a pulse domain device includes a multiplicand area calculator to provide an multiplicand area output for a multiplicand pulse train; a multiplier area calculator to provide a multiplier area output for a multiplier pulse train; a resultant product area (RPA) decoder to provide a RPA output using the multiplicand and multiplier area outputs; and a pulse timing calculator to provide RPA output pulse timing.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: March 31, 2020
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Gabriel Nallathambi, Jose C. Principe
  • Patent number: 10597636
    Abstract: A polymerizable unit that yields an electrochemically responsive polymer (advantageously pyrrole) is anchored by polymerization within a polycaprolactone matrix to form an electroactive scaffold upon which cells can be cultured and in which the micro- and nano-topological features of the polycaprolactone matrix are preserved. A scaffold manufactured in accordance with the preferred embodiment can support Schwann cells, which produce nerve growth factor when electrically stimulated. Nerve growth factor has been demonstrated to promote the regeneration of nerve tissue. By implanting the scaffold on which Schwann cells have been cultured into damaged nerve tissue and applying a voltage across the scaffold, nerve growth factor is produced, thereby promoting repair of the damaged nerve tissue.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: March 24, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: John Hardy, Christine E. Schmidt
  • Patent number: 10597761
    Abstract: Disclosed herein is a composite comprising a metal alloy matrix; where the metal alloy matrix comprises aluminum in an amount greater than 50 atomic percent; a first metal and a second metal; where the first metal is different from the second metal; and where the metal alloy matrix comprises a low temperature melting phase and a high temperature melting phase; where the low temperature melting phase melts at a temperature that is lower than the high temperature melting phase; and a contracting constituent; where the contracting constituent exerts a compressive force on the metal alloy matrix at a temperature between a melting point of the low temperature melting phase and a melting point of the high temperature melting phase or below the melting points of the high and low temperature melting phases.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: March 24, 2020
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Michele Viola Manuel, Charles Robert Fisher, Maria Clara Wright
  • Patent number: 10590517
    Abstract: Disclosed herein is a shape memory alloy comprising 48 to 50 atomic percent nickel, 15 to 30 atomic percent hafnium, 1 to 5 atomic percent aluminum; with the remainder being titanium. Disclosed herein too is a method of manufacturing a shape memory alloy comprising mixing together to form an alloy nickel, hafnium, aluminum and titanium in amounts of 48 to 50 atomic percent nickel, 15 to 30 atomic percent hafnium, 1 to 5 atomic percent aluminum; with the remainder being titanium; solution treating the alloy at a temperature of 700 to 1300° C. for 50 to 200 hours; and aging the alloy at a temperature of 400 to 800° C. for a time period of 50 to 200 hours to form a shape memory alloy.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: March 17, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Michele Viola Manuel, Derek Hsen Dai Hsu
  • Patent number: 10588306
    Abstract: Embodiments relate to smart mosquito and insect trap devices, networks and method for detecting, counting, trapping and discarding a population of mosquitoes and/or insects. The mosquito species include the ones such as Aedes mosquito species that can cause Zika virus diseases. The device comprising a housing (201) having a directional force through a narrow path (240) to move an insect or mosquito in a predetermined direction. The device comprises one or more detectors (255) to detect a presence of an insect or mosquito along the path (240). An isolated basket (260) or trap is included to trap the insect or mosquito at a location below or at an end of the path. A processor (352) tracks a count of a population in the basket based on detection of the presence of the insect or mosquito.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: March 17, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Byul Hur, William R. Eisenstadt
  • Patent number: 10584340
    Abstract: DNA aptamers that bind to tau protein at its phosphorylatable sites are identified. These disclosed DNA aptamers not only recognize tau at specific phosphorylatable sites, but also demonstrate inhibitory effects on phosphorylation and oligomer formation of tau protein. Molecular probes based on these disclosed DNA aptamers can be used as capture or detection agents to detect the levels of tau and phosphor-tau in cerebrospinal fluid as well as for cell-based or in vivo brain imaging in live animals or human. Compositions comprising these disclosed DNA aptamers can be used to arrest or treat the progression of tauopathy associated neurodegenerative disorders.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: March 10, 2020
    Assignees: University of Florida Research Foundation, Inc., Department of Veteran's Affairs
    Inventors: Ka W. Wang, Weihong Tan, Xiaowei Li, Hamad Yadikar, I-Ting Teng
  • Patent number: 10577639
    Abstract: The subject invention provides novel devices and methods for the detection and quantification of neutrophil elastase activity in biological samples.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: March 3, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Gregory S. Schultz, Daniel J. Gibson
  • Publication number: 20200061158
    Abstract: Disclosed herein are compositions and methods for treating obesity involving satiation gut peptide administration to the mouth of a subject for a predetermined dose and frequency. In other embodiments, materials and methods of treating certain psychological disorders are disclosed involving satiation gut peptides. In exemplary embodiments, the satiation gut peptide pertains to PYY.
    Type: Application
    Filed: September 5, 2019
    Publication date: February 27, 2020
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Sergei Zolotukhin, Andres Acosta
  • Patent number: 10573878
    Abstract: Embodiments of the present disclosure provide for cathodes having a metal sulfide thin layer, devices including cathodes, lithium ion batteries including cathodes, methods of making cathodes, and the like.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: February 25, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Kevin S. Jones, Nicholas G. Rudawski, Shadi Al Khateeb
  • Patent number: 10553711
    Abstract: Various aspects of tunable barrier transistors that can be used in high power electronics are provided. In one example, among others, a tunable barrier transistor includes an inorganic semiconducting layer; a source electrode including a nano-carbon film disposed on the inorganic semiconducting layer; a gate dielectric layer disposed on the nano-carbon film; and a gate electrode disposed on the gate dielectric layer over at least a portion of the nano-carbon film. The nano-carbon film can form a source-channel interface with the inorganic semiconducting layer. A gate field produced by the gate electrode can modulate a barrier height at the source-channel interface. The gate field may also modulate a barrier width at the source-channel interface.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: February 4, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Maxime G. Lemaitre, Xiao Chen, Bo Liu, Mitchell Austin McCarthy, Andrew Gabriel Rinzler
  • Patent number: 10542997
    Abstract: Devices and methods for removing tissue, which causes minimal pain or scarring. A hemostatic clamp having two arms with juxtaposeablefaces, can compress tissue between the faces of the arms so as to fuse a portion of the tissue therebetween. A locking mechanism maintains pressure on the arms until the skin is fused to create a skin tab. The unwanted tissue, such as a polydactyl digit, skin tag, or the like, can be excised with the clamp in position. When the locking mechanism is disengaged and the clamp is removed, the fused skin tab inhibits bleeding and the removal of the digit encourages any remaining underlying nerves to withdraw from the area of amputation. A related device can be used as a castration clamp to externally compress testicular-related tissues, such as ductiles, nerves, and blood vessels leading to the testicles, to castrate an animal. The castration clamp provides a quick, bloodless technique that eliminates the need for open wounds, which are subject to infection.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: January 28, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Juan Carlos Roig, Carlos Hondal
  • Patent number: 10538757
    Abstract: Embodiments of the present disclosure provide for nanozymes that can include a therapeutic agent, methods of making nanozymes, methods of using nanozymes, and the like. In some embodiments, the nanozymes can include a shell that can surround a hollow core that can be configured to receive a compound and the shell can include a recognition moiety and an enzyme.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: January 21, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Yunwei Charles Cao, Chen Liu
  • Patent number: 10541602
    Abstract: Various examples related to sinusoidal pulse width modulation (SPWM) techniques for harmonic and electromagnetic interference (EMI) noise suppression are provided. In one example, a method includes applying a DC offset to a sinusoidal modulation waveform to change an average duty cycle of a switching circuit; and controlling switching of an array of switches of the switching circuit based at least in part upon the offset sinusoidal modulation waveform and a carrier waveform, thereby reducing total energy. In another example, a system includes a switching circuit with an array of semiconductor switches that control application of a voltage source to a load; and controller circuitry that can control switching of the array of semiconductor switches by applying a DC offset to a sinusoidal modulation waveform to change an average duty cycle of the switching circuit.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: January 21, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Shuo Wang, Hui Zhao, Le Yang, Yingjie Zhang
  • Patent number: 10541601
    Abstract: Various examples related to electromagnetic interference (EMI) energy mitigation techniques are provided. In one example, a method includes adjusting switching angles of a switching circuit based on resolution bandwidths (RBWs) associated with an EMI frequency spectrum of the switching circuit and weight coefficients of the RBWs. The total energy of the switching circuit can be reduced by adjusting an average duty cycle of the switching circuit. EMI spectrum information can be determined based upon switching angles of a switching circuit. For example, weighted errors corresponding to differences between reference harmonic magnitudes and determined harmonic magnitudes can be determined. In response to a comparison of a maximum weighted error to a preset tolerance threshold, adjustment to the switching angles can be determined and/or applied.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: January 21, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Shuo Wang, Hui Zhao, Le Yang
  • Patent number: 10531806
    Abstract: Various examples are provided for brain state advisory systems using calibrated metrics and optimal time-series decompositions. In one embodiment, a method includes monitoring brainwave activity of a subject and classifying a brain state of the subject based upon the brainwave activity and a model of the brainwave activity. In another embodiment, brain states of the subject are modeled based upon the brainwave activity of the subject.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: January 14, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Jose Principe, Austin J. Brockmeier
  • Publication number: 20200003789
    Abstract: The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.
    Type: Application
    Filed: June 21, 2019
    Publication date: January 2, 2020
    Applicants: University of Florida Research Foundation, Inc., Banyan Biomarkers, Inc.
    Inventors: Kevin Ka-Wang WANG, Monika OLI, Ming-Cheng LIU
  • Patent number: 10517525
    Abstract: Various examples are provided for a smart mouth guard for diagnosis, quantification, and/or management of e.g., bruxism. In one example, among others, a diagnostic mouth guard includes a plurality of pressure sensors and processing circuitry configured to provide pressure sensor data to an external processing unit when located in an oral cavity. The diagnostic mouth guard may also include temperature, pH and/or inertia sensors. In another example, a system includes the diagnostic mouth guard and the external processing unit such as, e.g., a smart phone, table or computer. The diagnostic mouth guard can communicate with the external processing unit over a wireless channel.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: December 31, 2019
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Yong-Kyu Yoon, Xiaoyu Cheng, Gloria Jung-a Kim, Fong Wong
  • Patent number: 10521600
    Abstract: Aspects of system-on-chip (SoC) security architecture that supports systematic and efficient implementation, validation, and in-field upgrade of security policies are described. In one example, an apparatus can include at least one intellectual property (IP) core, a centralized reconfigurable security policy engine (RSPE) and at least one security wrapper. The RSPE implements actionable constraint based on a security policy and at least one event frame. A security wrapper is associated with an IP core. The security wrapper is configured to communicate an event frame to the RSPE in response to an event.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: December 31, 2019
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Swarup Bhunia, Atul Prasad Deb Nath