Abstract: Methods for derivatizing the surface of a substrate having a plurality of thiol groups thereon are disclosed herein. The method can include reacting the thiol groups with an o-quinone methide, which can optionally be generated by irradiating an o-quinone methide precursor compound. In some embodiments, the method can advantageously be reversible. Exemplary o-quinone methides having a cyclic alkyne attached thereto, and precursor compounds for generating such compounds, are also disclosed herein.
Type:
Application
Filed:
April 16, 2013
Publication date:
October 24, 2013
Applicant:
University of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center
Inventor:
University of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center
Abstract: Genetic material encoding luciferase from the marine coelenterate Renilla has been isolated and characterized. This genetic material allows the production of peptides for use as labels in bioluminescence assays or can itself be directly used to identify luciferase genes from related organisms.
Type:
Grant
Filed:
June 17, 1993
Date of Patent:
March 8, 1994
Assignee:
University of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center