Abstract: The present application provides a human joint energy harvesting apparatus for capturing the biomechanical energy of a joint to generate electrical energy. The generated electrical energy may provide a real-time power supply to the wearable electronics. The apparatus employs a linear slide rail mechanism and cooperates with the user's first limb and second limb to form a slider-crank mechanism, which converts the rotating motion of the joint into a linear motion of the linear slide rail mechanism. The bending beam converts the linear motion of the linear slide rail mechanism into a bending motion. A piezoelectric film may be bonded to the upper and lower surfaces of the bending beam. During walking, the bending beam is deformed, causing the piezoelectric film to be stretched or compressed to generate electrical energy. To harvest more energy, the bending beam used in the apparatus is designed to be subjected to forced motion and free vibration, and a proof mass is attached to it.

Abstract: An apparatus for patterning biological cells, and a method of patterning and coculturing biological cells using the apparatus. The apparatus includes a fluidic structure having an outlet and a plurality of inlets, the fluidic structure is arranged to facilitate a flow of a plurality of different cells in a cell suspension therethrough, wherein each of the plurality of inlets is arranged to facilitate a loading of the plurality of different cells from a plurality of supplies into the fluidic structure; and a flow controlling device arranged to control the flow of the plurality of different cells through the fluidic structure and/or the loading of the plurality of different cells from the plurality of supplies through the plurality of inlets; wherein the fluidic structure is further arranged to facilitate a simultaneous observation of the plurality of different cells arranged in a predetermined pattern in the fluidic structure.

Abstract: Methods, apparatuses, and systems for wireless power transfer (WPT) in ball-and-socket type structures are provided. A ball and ball-socket structure can include conductive windings and conductive plates having a variety of shapes to optimize WPT over different angles as the ball moves or rotates within the ball-socket. One or both of capacitive coupling and inductive coupling can be incorporated.

Abstract: A computer-implemented method and a related system for determining seismic hazard related data. The method includes processing geological/seismological data associated with an area of unknown hazard using a simulation model, and determining simulated ground motion intensity data associated with the area of unknown hazard. The simulation model is determined based on geological/seismological data associated with an area of known hazard and ground motion intensity data associated with the area of known hazard. Alternatively, or additionally, the method includes processing simulated ground motion intensity data associated with the area of unknown hazard with another simulation model.

Abstract: A method for analyzing neuropharmacology of a drug, including the steps of providing a set of brain activity maps representing changes of a brain activity of a living species under an influence of a plurality of known drugs each consisting of a known chemical structure; clustering the set of brain activity maps to form a plurality of functional classifiers; and classifying a brain activity map associated with a chemical compound using the functional classifiers so as to predict a neuropharmacology of the chemical compound.

Abstract: To improve the performance and accuracy of an image segmentation neural network, a cascaded robust learning framework for the segmentation of noisy labeled images includes two stages: a sample selection stage, and a joint optimization stage with label correction. In the first stage, the clean annotated samples are selected for network updating, so that the influence of noisy sample can be interactively eliminated. In the second stage, the label correction module works together with the joint optimization scheme to revise the imperfect labels. Thus, the training of the whole network is supervised by the corrected labels and the original ones.

Abstract: The present invention provides a high output voltage supercapacitor having a cathode including layers of phosphorene, an anode comprising zinc, and an organic-solvent-based electrolyte including zinc. The supercapacitor demonstrates a high anti-self-discharge. The organic electrolyte may include an anhydrous zinc salt, tetraethylammonium tetrafluoroborate, and propylene carbonate (Et4NBF4/PC). The electrochemical stability window of Et4NBF4/PC extends beyond 2.5 V. The supercapacitor can be charged to 2.5 V and possesses high initial discharge voltage. The supercapacitor delivered 130 F g?1 even after more than 9500 cycles at a current density of 0.5 A g?1. More importantly, the supercapacitor exhibits a capacitance retention of 70.16% even after 500 hours self-discharge behavior.

Abstract: A method of treating metastatic cancer in a subject in need thereof including administering an effective amount of a capping protein Z inhibitor to the subject. A method of inhibiting metastasis of cancer cells including administering an effective amount of a capping protein Z inhibitor.

Abstract: A method for streaming a video. The method includes determining a total bitrate for a segment of a video to be received and streamed; predicting a viewpoint of a user for the segment; and determining bitrates for one or more tiles in the segment based on the determined total bitrate and the predicted viewpoint.

Abstract: Various embodiments are directed to applications (e.g., classification of biological samples) of the analysis of the count, the fragmentation patterns, and size of cell-free nucleic acids, e.g., plasma DNA and serum DNA, including nucleic acids from pathogens, such as viruses. Embodiments of one application can determine if a subject has a particular condition. For example, a method of present disclosure can determine if a subject has cancer or a tumor, or other pathology. Embodiments of another application can be used to assess the stage of a condition, or the progression of a condition over time. For example, a method of the present disclosure may be used to determine a stage of cancer in a subject, or the progression of cancer in a subject over time (e.g., using samples obtained from a subject at different times).

Abstract: This invention relates to compounds of formula 1, 2 or 3 a pharmaceutically acceptable salt, or solvate thereof, wherein X1, Y, R1, R2, R3, R4, and R5 are as defined herein. The compounds are antimicrobial agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1, 2 or 3.

Abstract: The invention relates to a method for making a dielectric reflectarray antenna, and a dielectric reflectarray antenna made using such method. The method includes removing, from a substrate having a dielectric layer and a first outer metallic layer arranged on one side of the dielectric layer, the first outer metallic layer to form an intermediate substrate. The method also includes cutting the intermediate substrate to integrally form a dielectric reflectarray with an array of dielectric reflector elements of the dielectric reflectarray antenna.

Abstract: Segmentation of bony regions in MRI images of joints is automated using a two-stage process. In a first stage, a machine-learning image-slice categorizer is used to categorize image slices of the MRI image data as belonging to one of a set of image-slice categories, depending on presence or absence of bone and/or tendon in the image slice. In a second stage, a first instance of a machine-learning segmentation classifier is used to segment image slices that contain both bone and tendon into bone and non-bone regions, and a second instance of a machine-learning segmentation classifier is used to segment image slices that contain bone but not tendon into bone regions and non-bone regions. Results from the two segmentation classifiers can be combined across image slices to provide a final segmentation of the bony structures, including inflammatory regions, in the image data.

Abstract: A universal color coding system, and method of analyzing objects with multiple attributes using the color coding system. The color coding system includes a color mapper arranged to map a plurality of colors with a plurality of numerical codes, wherein the each of the plurality of numerical codes is a unique integer determined based on a combination of prime numbers; wherein each of the plurality of numerical codes is arranged to represent a unique color in color space wherein each of the prime numbers represents a respective basic color of the color space; and wherein the plurality of numerical codes are integers calculated based on addition and multiplication of a plurality of prime numbers.

Abstract: An energy harvester (100) includes: an inner band (110); an outer band (120) arranged to surround the inner band (110), wherein the inner band (110) is coupled to the outer band (120) at a fixed end (20) and the inner band (110) is spaced from the outer band (120) at a free end (30); and an energy generator (150) arranged to generate electric energy through relative movement between the inner band (110) and the outer band (120) at the free end (30). Also disclosed is a wearable device (10) including: a wearable strap formed by the inner band (110) and the outer band (120) of the energy harvester (100), and a mass (130) arranged to receive at least a portion of the wearable device (10).

Abstract: The present invention provides a method and a system for arranging base stations in a millimeter wave communication network. The method establishes a stochastic optimization framework for millimeter-wave base station deployment in the urban street geometry and provides a low-complexity user association arrangement which can well balance the workloads among BSs and reduce the outage probability by taking the time-varying nature of user equipments' positions and the susceptibility of millimeter-wave links to blockage effect into account. Compared with the state-of-the-art approaches, the present invention can effectively and efficiently reduce the outage probability in the long term.

Abstract: A system for ankle rehabilitation includes a motorized platform arranged to hold an ankle of a subject to be rehabilitated; a first sensor module arranged to detect signals representing movement intention of the ankle on the motorized platform; a second sensor module arranged to detect signals representing actual movement of the ankle on the motorized platform; and a processor arranged to process the signals detected by the first sensor module and the signals detected by the second sensor module, for control of movement of the motorized platform.

Abstract: A method for surface modification of nanoparticles includes the separate steps of removing ligands from the surface of the nanoparticles to form ligand-free nanoparticles, and mixing new ligands with the ligand-free nanoparticles to form modified nanoparticles.

Abstract: Methods for screening, diagnosing, or predicting presence, progression, or treatment effects of a cognitive dysfunction such as dementia based on an analysis of drawing behavior changes by a pre-trained Naïve Bayes method are provided. The methods include steps of obtaining drawing data of at least one image created by a test subject on a digital device and obtaining personal data of the test subject; reconstructing the at least one image based on the drawing data obtained; converting the drawing data to drawing features comprising a plurality of motion features and a plurality of geometric features; and determining probability that the test subject has a cognitive dysfunction based on the drawing features and the personal data by a pre-trained Naïve Bayes method with a greedy variable selection.

Abstract: Systems and methods for using determination of base modification in analyzing nucleic acid molecules and acquiring data for analysis of nucleic acid molecules are described herein. Base modifications may include methylations. Methods to determine base modifications may include using features derived from sequencing. These features may include the pulse width of an optical signal from sequencing bases, the interpulse duration of bases, and the identity of the bases. Machine learning models can be trained to detect the base modifications using these features. The relative modification or methylation levels between haplotypes may indicate a disorder. Modification or methylation statuses may also be used to detect chimeric molecules.