Patents Assigned to University of Hong Kong
  • Patent number: 12206144
    Abstract: Provided is an aqueous redox flow battery comprising a positive electrode, a negative electrode, a posolyte chamber containing a posolyte in a solvent, a negolyte chamber containing a polysulfide based negolyte and a soluble organic catalyst in a solvent, and a separator disposed between the posolyte chamber and the negolyte chamber, wherein the soluble organic catalyst has a potential lower than the polysulfide based negolyte.
    Type: Grant
    Filed: March 25, 2022
    Date of Patent: January 21, 2025
    Assignee: The Chinese University of Hong Kong
    Inventors: Yi-Chun Lu, Jiafeng Lei
  • Publication number: 20250022362
    Abstract: An electronic reader for electro-chemical transistors (OECT) includes a potential output control module that controls the Vd, Vs, and Vg for the OECT under test, a high accuracy current monitor module which contains a transimpedance amplifier (TIA) used to control the output voltage and convert the input channel current Ids into a voltage value. A microcontroller (MCU) that controls the working sequences of the TIA so as to realize the specific characterization mode and enable an adjustable output voltage range. The MCU further controls a programmable sampling rate of up to 200 k samples per second (SPS) with low noise by down-sampling the base rate, convolution processing it and interpolating it back to ah high frequency, but without the noise. The device is small enough to be worn by a user and its output is sent to a mobile device for reading.
    Type: Application
    Filed: November 30, 2022
    Publication date: January 16, 2025
    Applicant: The University of Hong Kong
    Inventors: Shiming ZHANG, Xinyu TIAN, Kwok Leung CHAN, Dingyao LIU, Jing BAI
  • Patent number: 12193791
    Abstract: A handheld device for photoacoustic microscopy. The handheld device includes an optical assembly, a light beam scanner and a transducer unit. The optical assembly is arranged to provide a light beam. The light beam scanner includes a reflector arranged to reflect the light beam from the optical assembly to provide a reflected light beam to an object, a first drive mechanism operable to move the reflector relative to the optical assembly to move the reflected light beam relative to the object, and a second drive mechanism operable to move the reflector relative to the optical assembly to move the reflected light beam relative to the object. The transducer unit is arranged to detect photoacoustic signals emitted by the object in response to receiving the reflected light beam.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: January 14, 2025
    Assignee: City University of Hong Kong
    Inventors: Lidai Wang, Jiangbo Chen
  • Patent number: 12190998
    Abstract: An aberration in a fetal genome can be identified by analyzing a sample of fetal and maternal DNA. Classifications of whether an aberration (amplification or deletion) exists in a subchromosomal region are determined using count-based and size-based methods. The count classification and the size classification can be used in combination to determine whether only the fetus or only the mother, or both, have the aberration in the subchromosomal region, thereby avoiding false positives when the mother has the aberration and the fetus does not.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: January 7, 2025
    Assignee: The Chinese University of Hong Kong
    Inventors: Yuk-Ming Dennis Lo, Rossa Wai Kwun Chiu, Kwan Chee Chan, Peiyong Jiang, Cheuk Yin Jandy Yu
  • Patent number: 12189844
    Abstract: An eye-gaze tracking apparatus and a method of eye-gaze tracking. The eye-gaze tracking apparatus comprises: a plurality of foreground cameras each arranged to capture at least a portion of a target view area of a user; and an eye-gaze estimation module having at least one eye-gaze camera each arranged to capture an image an eye of the user, so as to estimate a position of a pupil of the eye based on the image of the eye; wherein each of the plurality of foreground cameras includes a field-of-view (FOV) being different from each other.
    Type: Grant
    Filed: January 5, 2023
    Date of Patent: January 7, 2025
    Assignee: The Education University of Hong Kong
    Inventors: Hong Fu, Bin Fu, Yang Zheng, Ruimin Li
  • Publication number: 20250000979
    Abstract: The present disclosure generally relates to various phototriggered drug release and photoreactions, including reactions generally based on triplet-triplet energy transfer with light excitation at long wavelengths. One aspect of the present disclosure is directed to systems and methods for absorbing energy in a photosensitizer, transferring that energy by triplet-triplet energy transfer to cleave a cleavable or other active moiety causing the release of a releasable moiety. One aspect relates to a composition comprising a photosensitizer which is capable of singlet-to-triplet (S-T) activation at a near-infrared (NIR) wavelength, a cleavable moiety to accept triplet-triplet energy transfer from the photosensitizer in a higher energy state to cause cleavage of the cleavable moiety, and a releasable moiety releasable from the composition upon cleavage of the cleavable moiety. Such systems and methods may be used in various biological or physical applications.
    Type: Application
    Filed: June 7, 2024
    Publication date: January 2, 2025
    Applicant: The University of Hong Kong
    Inventors: Weiping Wang, Kaiqi Long
  • Publication number: 20250004094
    Abstract: A system for suppressing radio frequency interference (RFI) or electromagnetic interference (EMI) in a radar or magnetic resonance imaging system that scans target(s) with energy and receives signals that reflect or echo from the target(s). The system involves obtaining RFI/EMI data in the absence of signals of interest in the scanning system using at least one primary antenna and a plurality of reference antennas. The reference antennas are designed and arranged to detect RFI/EMI signals but not signals of interest in the scanning system. Simultaneously a model, e.g. CNN, is trained with the RFI/EMI data to determine the non-linear signal mappings among primary and reference antennas. The trained model is applied to predict the RFI/EMI received by the primary antenna in the presence of signals of interest. Finally, the RFI/EMI signals received by the primary antenna are removed by subtracting out the predicted RFI/EMI.
    Type: Application
    Filed: December 1, 2022
    Publication date: January 2, 2025
    Applicant: The University of Hong Kong
    Inventors: Ed Xuekui WU, Yujiao ZHAO, Tze Lun LEONG
  • Patent number: 12180549
    Abstract: Embodiments of this invention provide methods, systems, and apparatus for determining whether a fetal chromosomal aneuploidy exists from a biological sample obtained from a pregnant female. Nucleic acid molecules of the biological sample are sequenced, such that a fraction of the genome is sequenced. Respective amounts of a clinically-relevant chromosome and of background chromosomes are determined from results of the sequencing. The determination of the relative amounts may count sequences of only certain length. A parameter derived from these amounts (e.g. a ratio) is compared to one or more cutoff values, thereby determining a classification of whether a fetal chromosomal aneuploidy exists. Prior to sequencing, the biological sample may be enriched for DNA fragments of a particular sizes.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: December 31, 2024
    Assignee: The Chinese University of Hong Kong
    Inventors: Yuk-Ming Dennis Lo, Rossa Wai Kwun Chiu, Kwan Chee Chan
  • Publication number: 20240423496
    Abstract: A system and devices provide for accurate localization of orthopedic implants based on magnetic tracking approach (MTA) technology and without radiation. The system includes at least one magnetic beacon that is joined to an orthopedic screw/implant fixed to a patient's spine. A detector in the form of a magnetic sensor array detects the magnetic field from the beacon and produces an electrical signal in response thereto. A computer using a multi-objective magnetic location algorithm tracks the spatial position and movement of the beacon based on the electrical signal, and hence tracks the patient's spine.
    Type: Application
    Filed: July 28, 2022
    Publication date: December 26, 2024
    Applicant: The University of Hong Kong
    Inventors: Weichen QI, Teng ZHANG, Pui Yin CHEUNG
  • Publication number: 20240426951
    Abstract: An ultrafast wide-field quantum sensing device using a neuromorphic event-based vision sensor includes a laser generating a laser beam; a dichroic mirror directing the laser beam onto a diamond sample and passing the laser beam reflected from the diamond, and an event camera receiving from the dichroic mirror the beam reflected from the diamond. A source of microwave energy applied to the diamond. A pulse generator synchronizes the microwave source and the event camera to create CW-ODMR measurements, wherein trigger pulses from the pulse generator are applied to the camera and microwave source. The optically detected magnetic resonance (ODMR) resonance frequency is determined based on the CW-ODMR measurements.
    Type: Application
    Filed: November 4, 2022
    Publication date: December 26, 2024
    Applicant: The University of Hong Kong
    Inventors: Zhiqin CHU, Can LI, Zhiyuan DU, Gupta MADHAV, Feng XU, Ngai WONG
  • Publication number: 20240415152
    Abstract: The present invention is concerned with a method of improving health of fish. The method has a step of feeding the fish with a fish feed, wherein the fish feed in its dried state has 60-93.35 mg/kg of zinc oxide (ZnO) particles.
    Type: Application
    Filed: June 6, 2023
    Publication date: December 19, 2024
    Applicant: City University of Hong Kong
    Inventors: Wenxiong WANG, Shuoli MA
  • Publication number: 20240415918
    Abstract: The present invention relates to the field of chemical and pharmaceutical technologies, in particular to a polypeptide and its use as a CCK receptor agonist/antagonist. Experiments show that the polypeptide provided by the present invention has a high agonistic/antagonistic activity on CCK receptors. Compared with the polypeptide CCK4, the polypeptide according to the present invention has a longer half-life and duration of efficacy in vivo. Experiments show that the polypeptide according to the present invention produces a significant improvement on the spatial memory deficiency of senile mice, memory-deficient senile mice, and Alzheimer's mice, and thus has a great application potential.
    Type: Application
    Filed: June 30, 2022
    Publication date: December 19, 2024
    Applicants: Centre for Regenerative Medicine & Health, Hong Kong Institute of Science & Innovation, Chinese, City University of Hong Kong
    Inventors: Mickey Daniel Tortorella, Jufang He
  • Patent number: 12168944
    Abstract: The present invention provides an absorption-desorption based Carnot battery designed to achieve a high-efficiency, large-density, and low-loss conversion battery system for power-heat-power purpose. Based on the rational operating strategies, the current Carnot battery system design demonstrates outstanding energy storage density and round-trip efficiency, while the self-discharging loss is minimal even after prolonged standby time. The battery system of the present invention also enables further designs with flexibility in adopting different operating modes for versatile functions to provide electricity, heating, and cooling.
    Type: Grant
    Filed: December 20, 2023
    Date of Patent: December 17, 2024
    Assignee: City University of Hong Kong
    Inventors: Wei Wu, Yunren Sui, Haosheng Lin, Zhixiong Ding
  • Patent number: 12163979
    Abstract: A nano scale robotic system for single cell DNA sequencing of a strand of DNA positioned on a slide utilizes an atomic force microscope (AFM) having an end effector in the form of a cantilever with a tip. The AFM causes its cantilever tip to scan over the base pairs of the DNA strand. A pair of spaced-apart electrodes at the tip makes contact with opposite sides of the DNA strand and the current between bases of the DNA strand is measured by a current measurement system connected to the electrodes. An artificial intelligence-based data analytic system determines the DNA sequence based on the current from the current measuring system. The AFM tip is guided over the DNA strand by comparing compressed desired intensity local scan images and compressed actual intensity local scan images and using the difference to control the location of the tip.
    Type: Grant
    Filed: October 27, 2022
    Date of Patent: December 10, 2024
    Assignees: VERSITECH LIMITED, City University of Hong Kong
    Inventors: Ning Xi, Song Wang, Pengtao Liu, Zhiyong Sun, Lixin Dong, Chaojian Hou, Donglei Chen, Wenqi Zhang
  • Patent number: 12162899
    Abstract: A germole-fused diarylethene-based compound is presented that includes a germanium-containing five-membered ring structure with an ethene bridge fused to photoactive bis-aryl rings. The germole-fused diarylethene-based compound isomerizes between a ring-open and a ring-closed form upon irradiation and to allow optical storage or photoswitching devices. A method to form the germole-fused diarylethene-based compound is through a rhodium catalyzed coupling between a 1-germyl-aryl-2-boronic ester, 1-germyl-heteroaryl-2-boronic ester, or 1-germyl-alkenyl-2-boronic ester with the 1,2-diarylethyne. The germole-fused diarylethene-based compounds display tunable photophysical properties of the photogenerated closed form, with excellent thermal irreversibility and a robust fatigue resistance.
    Type: Grant
    Filed: November 30, 2022
    Date of Patent: December 10, 2024
    Assignee: The University of Hong Kong
    Inventors: Vivian Wing-Wah Yam, Nathan Man-Wai Wu, Tony Ho-Ching Fung
  • Patent number: 12157683
    Abstract: A composite material for floating on a contaminated water source, including: A) a polymeric structure having a network of interconnected porous channels; and B) a carbonous material dispersed within the polymeric structure, the carbonous material has a functionalized surface. The composite material has a density of less than 1 g/cm3, and the contaminated water source contains a low-boiling-point contaminant. The polymeric structure draws contaminated water from the contaminated water source into the polymeric structure via capillary action, and the functionalized surface removes the low-boiling point contaminant from the contaminated water. A method of purifying water using the composite material as mentioned herein and a kit for harvesting purified water including the composite material as mentioned herein.
    Type: Grant
    Filed: January 7, 2022
    Date of Patent: December 3, 2024
    Assignee: City University of Hong Kong
    Inventors: Chun-Sing Lee, Shengliang Li, Zhongming Huang, Yingpeng Wan
  • Patent number: 12157142
    Abstract: A metallic nanowire:conductive polymer composite is fabricated. A metallic nanowire layer is formed by a process that leaves an organic ligand residue on the metallic nanowire layer. A conductive polymer film is formed on a supporting substrate. The metallic nanowire layer is integrated with the conductive polymer film to form a metallic nanowire:conductive polymer composite. The metallic nanowire:conductive polymer composite is wet by a reaction solution including a source of metal ions, at least one acid, and a solvent for a period of time sufficient to remove the organic ligand residues from the metallic nanowire layer and sufficient to grow metal nanoparticles from the source of metal ions to create metal interconnections at junctions where the two or more nanowires in the metallic nanowire layer touch each other. Following growth of the nanoparticles, the nanowire:conductive polymer composite is removed from the reaction solution and dried.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: December 3, 2024
    Assignee: The University of Hong Kong
    Inventors: Chik Ho Choy, Jinwook Kim
  • Publication number: 20240391773
    Abstract: The present invention is concerned with a method of direct synthesis of co-products of at a first co-product and a second co-product. The first co-product is superhydrophilic carbon nitride thin film and the second co-product is superhydrophilic carbon nitride powder. The method has a step of using a guanidine carbonate salt as a precursor material. The present invention is also concerned with carbon nitride co-products. The carbon nitride co-products has a first co-product of superhydrophilic carbon nitride thin film and a second co-product of superhydrophilic carbon nitride powder. The superhydrophilic carbon nitride thin film has chemical formula of CNx, wherein x is 0.86-1.04, and the superhydrophilic carbon nitride powder has a chemical formula of g-C3N4.
    Type: Application
    Filed: May 23, 2023
    Publication date: November 28, 2024
    Applicant: City University of Hong Kong
    Inventors: Thuc Hue LY, Quoc Huy THI, Ping MAN
  • Patent number: 12152843
    Abstract: A radiative cooling apparatus including a layer of a material. The layer defines an exterior face. The material has a composition such that the layer is configured to reflect, at the exterior face, at least partly of the incoming electromagnetic radiation of at least some wavelengths in the solar spectrum. The layer is further configured to emit thermally-generated electromagnetic emission of at least some mid-infrared wavelengths out from the exterior face. Ceramics provided by embodiments of the invention could produce extra cooling effect without any electricity consumption, creating a prominent benefit to the energy saving of air conditioning systems of buildings.
    Type: Grant
    Filed: August 3, 2022
    Date of Patent: November 26, 2024
    Assignee: City University of Hong Kong
    Inventors: Kaixin Lin, Siru Chen, Tong Zhu, Yihao Zhu, Hau Him Lee, Tsz Chung Ho, Chi Yan Tso
  • Patent number: 12152301
    Abstract: Provided is a method for synthesizing 2H/1T? transition metal dichalcogenide (TMD) heterophase junctions. Synthesis of vertical 2H/1T? MoS2 heterophase junction is achieved by growing 2H MoS2 monolayers on a mica substrate under pure Ar carrier gas, and then growing 1T? MoS2 nanoribbons on top of the 2H MoS2 monolayers by changing the carrier gas from pure Ar to a mixture of Ar and H2 gases. The integrated devices based on 2H/1T? MoS2 heterophase structures display typical rectifying behavior with a current rectifying ratio of over 102 and achieve a responsivity of 1.07 A/W at 532 nm with an ultra-low dark current of lower than 10-11 A. These superior features make 2H/1T? MoS2 heterophase structure a promising candidate for future rectifiers as well as photodetectors. More importantly, the provided synthesis method can pave the way toward tailoring the phase in MoS2 to promote the performance of electronic devices.
    Type: Grant
    Filed: May 21, 2023
    Date of Patent: November 26, 2024
    Assignee: City University of Hong Kong
    Inventors: Hua Zhang, Yongji Wang, Wei Zhai