Patents Assigned to University of Houston
  • Publication number: 20190144308
    Abstract: Systems and methods discussed herein may harness geothermal energy from geothermal wells, such as a retrofitted decommissioned well, that may be utilized for water desalination. Hot fluids extracted from the geothermal well may be utilized to generate geothermal energy that can be utilized to power desalination devices to removal minerals and/or salt from produced water from another well. These hot fluids may be recirculated back into the geothermal well to gather heat and to form a closed-looped system that provides thermal energy to the desalination unit. The treated water may be stored for latter agricultural, municipal, and/or other use, or it may be utilized further hydraulic fracturing.
    Type: Application
    Filed: January 11, 2019
    Publication date: May 16, 2019
    Applicant: University of Houston System
    Inventor: Amin Kiaghadi
  • Publication number: 20190145869
    Abstract: In some embodiments, the present disclosure pertains to a method for retrieving at least one molecular recognition element in a fixed tissue. In some embodiments the method comprises preparing a solution comprising at least one aldehyde-scavenging agent. In some embodiments, the method comprises contacting the fixed tissue with the solution. In some embodiments, the tissue is fixed with an aldehyde-based cross-linking agent. In some embodiments, a reaction of the aldehyde-scavenging agent with the aldehydes comprising the cross-linking agent retrieves the at least one molecular recognition element. In some embodiments, the at least one molecular recognition element comprises of amino acids, peptides, proteins, nucleic acids, carbohydrates, lipids, or a combination thereof.
    Type: Application
    Filed: January 9, 2019
    Publication date: May 16, 2019
    Applicant: University Of Houston System
    Inventors: Jason Eriksen, Craig Vollert, Steven Bark, Wilna Moree
  • Publication number: 20190144952
    Abstract: The invention provides methods of enriching and isolating novel microbial organisms, such as rhizobacteria, that promote the growth of plants by recreating the rhizosphere in a laboratory setting. The methods of the invention can be used to produce and characterize beneficial microbes grown at the root-soil interface and provide a technique for selectively enriching bacteria that live in close association with plants and foster the growth thereof.
    Type: Application
    Filed: May 9, 2017
    Publication date: May 16, 2019
    Applicant: University of Houston System
    Inventor: Michael LaMontagne
  • Publication number: 20190144291
    Abstract: Embodiments of the invention generally provide compositions of crystalline zeolite materials with tailored crystal habits and the methods for forming such crystalline zeolite materials. The methods for forming the crystalline zeolite materials include binding one or more zeolite growth modifiers (ZGMs) to the surface of a zeolite crystal, which results in the modification of crystal growth rates along different crystallographic directions, leading to the formation of zeolites having a tailored crystal habit. The improved properties enabled by the tailored crystal habit include a minimized crystal thickness, a shortened internal diffusion pathlength, and a greater step density as compared to a zeolite having the native crystal habit prepared by traditional processes. The tailored crystal habit provides the crystalline zeolite materials with an aspect ratio of about 4 or greater and crystal surfaces having a step density of about 25 steps/?m2 or greater.
    Type: Application
    Filed: November 8, 2018
    Publication date: May 16, 2019
    Applicant: University of Houston System
    Inventors: Jeffrey D. Rimer, Manjesh Kumar
  • Patent number: 10285961
    Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: May 14, 2019
    Assignee: University of Houston System
    Inventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
  • Patent number: 10288804
    Abstract: Electronic-photonic integrated circuits (EPICs), such a monolithically integrated circuit, are considered to be next generation technology that takes advantage of high-speed optical communication and nanoscale electronics. Atomically thin transition metal dichalcogenides (TMDs) may serve as a perfect platform to realize EPIC. The generation and detection of light by a monolayer TMD at nanoscale through surface plasmon polaritons (SPPs) may be utilized to provide optical communication. The bidirectional nature of the TMDs allow such a layer to be utilizes as part of emitters or photodetectors for EPICs.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: May 14, 2019
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Jiming Bao, Zhuan Zhu, Zhiming Wang
  • Publication number: 20190133932
    Abstract: Provided herein are fluorinated compounds having chemical structures: (I) where n is 0 or greater, or (II) where m and n are 0 or greater, or an amino acid, a soluble polymer, an oligo(ethylene glycol), a poly(ethylene glycol), or a carbohydrate each fluorinated with perfluorocarbons having the chemical structure (III) where n is 0 or greater. These fluorinated compounds are utilized in contact lenses to impart lipid-resistant, protein-resistant and biofouling-resistant properties, thus reducing discomfort and infection caused by contact lens wear without changing its transmission characteristics. Also provided is an ophthalmic drug delivery system comprising at least one of the compounds described above embedded in the contact lens and a kit to incorporate the ophthalmic into a contact lens. Methods for incorporating these compounds onto a contact lens without affecting transparency and for use in treating an ophthalmologic-associated condition are provided.
    Type: Application
    Filed: April 28, 2017
    Publication date: May 9, 2019
    Applicant: University of Houston System
    Inventors: Guoting Qin, Chengzhi Cai
  • Patent number: 10281796
    Abstract: Disclosed is a nonlinear optical (NLO) material for use in deep-UV applications, and methods of fabrication thereof. The NLO is fabricated from a plurality of components according to the formula AqByCz and a crystallographic non-centrosymmetric (NCS) structure. The NLO material may be fabricated as a polycrystalline or a single crystal material. In an embodiment, the material may be according to a formula Ba3ZnB5PO14.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: May 7, 2019
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: P. Shiv Halasyamani, Hongwei Yu
  • Patent number: 10283690
    Abstract: A method of manufacturing a thermoelectric material comprising: ball-milling a compound comprising a plurality of components, the first component M comprising at least one of a rare earth metal, an actinide, an alkaline-earth metal, and an alkali metal, the second component T comprising a metal of subgroup VIII, and the third component X comprises a pnictogen atom. The compound may be ball-milled for up to 5 hours, and then thermo-mechanically processed by, for example, hot pressing the compound for less than two hours. Subsequent to the thermo-mechanical processing, the compound comprises a single filled skutterudite phase with a dimensionless figure of merit (ZT) above 1.0 and the compound has a composition following a formula of MT4X12.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: May 7, 2019
    Assignees: UNIVERSITY OF HOUSTON SYSTEM, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Qing Jie, Zhifeng Ren, Gang Chen
  • Publication number: 20190126517
    Abstract: A methodology is disclosed to produce nanostructured carbon particles that act as effective reinforcements. The process is conducted in the solid state at close to ambient conditions. The carbon nanostructures produced under this discovery are nanostructured and are synthesized by mechanical means at standard conditions. The benefit of this processing methodology is that those carbon nanostructures can be used as effective reinforcements for composites of various matrices. As example, are to demonstrate its effectiveness the following matrices were including in testing: ceramic, metallic, and polymeric (organic and inorganic), as well as bio-polymers. The reinforcements have been introduced in those matrices at room and elevated temperatures. The raw material is carbon soot that is a byproduct and hence abundant and cheaper than pristine carbon alternatives (e.g. nanotubes, graphene).
    Type: Application
    Filed: August 21, 2018
    Publication date: May 2, 2019
    Applicant: University of Houston System
    Inventors: Francisco C. Robles, Hector A. Calderon, Anderson Okonkwo
  • Publication number: 20190125779
    Abstract: Novel treatment methods of controlling cell hyperexcitability occurring in a neurological disease or disorder associated with epileptogenesis or cardiac disorder are disclosed herein. Novel pharmaceutical compositions comprising adenosine or adenosine agonists and at least one selected from phytocannabinoids and terpenes are disclosed.
    Type: Application
    Filed: December 30, 2015
    Publication date: May 2, 2019
    Applicant: University of Houston System
    Inventors: Jokubas Ziburkus, Kiran Kumar Akula, Ahmad Abdulla
  • Publication number: 20190125185
    Abstract: Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.
    Type: Application
    Filed: December 21, 2018
    Publication date: May 2, 2019
    Applicant: University of Houston System
    Inventors: Kirill V. Larin, Manmohan Singh, Jiasong Li, Zhaolong Han, Michael D. Twa
  • Patent number: 10266702
    Abstract: A method of forming a self-cleaning coating on a substrate comprises the step of selecting a substrate, cleaning the substrate, and/or roughening the substrate using an abrasive. In an embodiment, roughening of the substrate create microscopic tortuous grooves. Another embodiment of the method comprises coating the roughened surface with at least one hydrophobic chemical agent. In an exemplary embodiment, the hydrophobic chemical agent covalently binds with the substrate creating nanoscopic grooves. Another embodiment of the present disclosure pertains to an apparatus for depositing a self-cleaning coating on a flat substrate. A further embodiment of the present disclosure pertains to a self-cleaning coating on a substrate comprising a hydrophobic chemical agent covalently bonded to at least one roughened surface of the substrate.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: April 23, 2019
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Seamus Curran, Kang-Shyang Liao, Killian Barton
  • Patent number: 10246489
    Abstract: In an embodiment, the present disclosure pertains to a composition for inhibiting calcium oxalate monohydrate crystal growth comprising at least one isolated polypeptide comprising a plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal; and a plurality of amino acids spacers, wherein the amino acid spacers are arranged in varying sequences between the plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal. In some embodiments, the present disclosure related to a method of controlling calcium oxalate monohydrate crystal growth in a subject in need thereof comprising administering to the subject therapeutically effective amount of the calcium oxalate monohydrate inhibiting polypeptide. In some embodiments, the present disclosure relates to a method of identifying calcium oxalate monohydrate inhibiting peptides.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: April 2, 2019
    Assignees: UNIVERSITY OF HOUSTON, RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Jeffrey D. Rimer, Pankaj Karande
  • Publication number: 20190093440
    Abstract: Reduced order modeling is used in the present systems and methods for monitoring the health of a system and is particularly useful in monitoring the health and estimating the remaining useful life of blow out preventer (BOP) annular used in an oil or gas well. A reduced order model is a linear low order characterization of the system that describes the annular behavior with a small number of parameters that can be interpreted physically. The reduced order model is then identified and adapted in real-time in order to detect the change in the system behavior and characteristics. This adaptation helps in drawing conclusions on diagnostics and prognostics of the physical system.
    Type: Application
    Filed: March 22, 2017
    Publication date: March 28, 2019
    Applicant: University of Houston System
    Inventors: Matthew Franchek, Oussama Hattab, Moadh Mallek
  • Patent number: 10240010
    Abstract: A composition and method for fabricating graphitic nanocomposites in solid state matrices is presented. The process for fabricating graphitic nanocomposites in solid state matrices may include selecting one or a mixture of specific graphitic nanomaterials. The graphitic nanomaterial(s) may be functionalizing with a moiety similar to the building blocks of the solid state matrices. The functionalized graphitic nanomaterials are mixed with the building blocks of the solid state matrices. The mixture may be cured, which causes in situ formation of the sol-gel solid state matrices that entraps and/or covalently links with the graphitic nanomaterials during the network growing process. This process allows the nanomaterials to be introduced into the matrices homogeneously without forming large aggregations.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: March 26, 2019
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Seamus Curran, Kang-Shyang Liao, Alexander Wang
  • Patent number: 10243127
    Abstract: Discussed herein are half-Heusler thermoelectric materials including niobium, iron, antimony, and titanium that are formed by ball-milling and hot-pressing the ball-milled power to obtain various thermoelectric properties and an average grain size above 1 ?m.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: March 26, 2019
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Zhifeng Ren, Ran He
  • Patent number: 10235344
    Abstract: A rank-based score normalization framework that partitions matching scores into subsets and normalize each subset independently. Methods include implementing two versions of the framework: (i) using gallery-based information (i.e., gallery versus galleryscores), and (ii) updating available information in an online fashion. The methods improve the detection and identification rate from 20:90% up to 35:77% for Z-score and from 25:47% up to 30:29% for W-score.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: March 19, 2019
    Assignee: THE UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Panagiotis Moutafis, Ioannis A. Kakadiaris
  • Publication number: 20190054461
    Abstract: A multi-use combined micro and nanowell plate may provide nanowell arrays within the individual microwells of the plate. One or more microwells of the plate may provide an array of nanowells disposed at the bottom of the microwell. The combined micro and nanowell plate may be formed from a top frame with voids defining the microwells, and a bottom plate with voids defining the array of nanowells. When the top frame and the bottom plate are joined, the nanowell arrays may be aligned with the microwells to provide a combined micro/nanowell.
    Type: Application
    Filed: September 30, 2016
    Publication date: February 21, 2019
    Applicant: UNIVERSITY OF HOUSTON SYSTEM
    Inventor: Navin Varadarajan
  • Patent number: 10207469
    Abstract: Nanopantography is a method for patterning nanofeatures over large areas. Transfer of patterns defined by nanopantography using highly selective plasma etching, with an oxide layer of silicon serving as a hard mask, can improve patterning speed and etch profile. With this method, high aspect ratio features can be fabricated in a substrate with no mask undercut. The ability to fabricate complex patterns using nanopantography, followed by highly selective plasma etching, provides improved patterning speed, feature aspect ratio, and etching profile.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: February 19, 2019
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Vincent M. Donnelly, Demetre J. Economou, Siyuan Tian