Patents Assigned to UNIVERSITY OF JEDDAH
  • 2-(5-aminopyridin-2-yl)-N-benzylacetamides and use thereof in the treatment of acute myeloid leukemia
    Patent number: 12285418
    Abstract: Three compounds having a common molecular template of 2-(5-(N-acylamino)pyridin-2-yl)-N-benzylacetamide (Compounds I, II and I) are identified as potential anticancer therapeutic agents, and for the treatment of Acute Myeloid Leukemia (AML) in particular. Compound I was specifically designed to target AML cells, inhibit growth, and induce cell death. Compound I demonstrated a dose-dependent effect on AML cell lines HL-60, Mv4-11, KG-1a, and K562.
    Type: Grant
    Filed: August 29, 2024
    Date of Patent: April 29, 2025
    Assignees: University of Jeddah, King Abdulaziz University
    Inventors: Roaa M. Alreemi, Hind A. Alkhatabi, Abdelsattar M. Omar, Mohammed A. Baradwan, Yosra A. Muhammad, Peter Natesan Pushparaj, Mohammad Basabrain, Moustafa E. El-Araby
  • Aryl-1,2,3-triazole compounds, pharmaceutical composition thereof and method for treatment of breast cancer
    Patent number: 12258321
    Abstract: Compounds belonging to the group of N-benzyl-2-(4-(4-substituted-1H-1,2,3-triazol-1-yl)phenylacetamides have cytotoxic activities against MCF7 breast cancer cells, and are useful in therapeutic regimes for breast cancer. The N-benzyl-2-(4-(4-substituted-1H-1,2,3-triazol-1-yl)phenylacetamides also have beneficial effects on BAX, BCL-2, MCL-1 and MAPK pathways within MCF& breast cancer cells.
    Type: Grant
    Filed: October 14, 2024
    Date of Patent: March 25, 2025
    Assignees: University of Jeddah, King Abdulaziz University, Helwan University
    Inventors: Roaa M. Alreemi, Hind A. Alkhatabi, Mohammed A. Baradwan, Abdelsattar M. Omar, Moustafa E. El-Araby, Yara E. Mansour, Samar S. Fatahala, Ahmed M. Said, Shahenda Mahgoub
  • Wearable biosensors and applications thereof
    Patent number: 11813057
    Abstract: Conformable and wearable sensors with integrated on-chip gate for the detection of biomolecules, chemicals, and other substrates and applications thereof are provided. Biosensor chips can be built with In2O3 nanoribbon field-effect transistors. Biosensor chips can conform to features of a human body, enabling ability for individuals to wear a biosensor.
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: November 14, 2023
    Assignees: University of Southern California, The Regents of the University of California, University of Jeddah
    Inventors: Chongwu Zhou, Mohammed R. Amer, Ahmad N. Abbas, Qingzhou Liu, Mervat Alharbi
  • THERMOCOUPLE-BASED DISTILLATION MODULE AND METHOD
    Publication number: 20220401881
    Abstract: A membrane distillation (MD) module includes a first MD sub-module including a first thermocouple; a second MD sub-module including a second thermocouple; and a distillation membrane sandwiched between the first MD sub-module and the second MD sub-module. A hot chamber of the first MD sub-module is closed by the distillation membrane, and a cold chamber of the second MD sub-module is closed by the distillation membrane.
    Type: Application
    Filed: November 19, 2020
    Publication date: December 22, 2022
    Applicants: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY, UNIVERSITY OF JEDDAH
    Inventors: Khaled bin Bandar AL SAUD, Ahmad ALSAADI, Noreddine GHAFFOUR