Abstract: A combined antigen having at least three portions of human cytomegalovirus (HCMV) proteins and characterized by an enhanced ability to bind HCMV-specific antibodies, for use in assays for the detection of HCMV-specific antibodies and as a vaccine to confer protective immunity against HCMV-mediated diseases.
Type:
Grant
Filed:
February 22, 1996
Date of Patent:
September 1, 1998
Assignee:
University of Limburg
Inventors:
Catharina A. Bruggeman, Cornelis Vink, Albert Ramon, Frans Stals