Patents Assigned to University of Manitoba
  • Patent number: 10927856
    Abstract: Pump-controlled hydraulic circuits are more efficient than valve-controlled circuits, as they eliminate the energy losses due to flow throttling in valves and require less cooling effort. Presently existing pump-controlled solutions for single rod cylinders encounter an undesirable performance during certain operating conditions. Novel circuit designs employ use of different charge pressures on a pair of pilot-operated charging-control valves or different piston areas and/or spring constants on a shuttle-type charging control valve to shift a critical loading region in a load-force/actuator-velocity plane to a lower load force range, thereby reducing the undesired oscillations experienced in the response of the typical critical loading region.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: February 23, 2021
    Assignee: University of Manitoba
    Inventors: Ahmed A. Imam, Nariman Sepehri
  • Patent number: 10898079
    Abstract: Detection of intravascular plaque in OCT images is carried out by obtaining images of vascular tissue from a vascular component by OCT either in a static mode of a single image or in a dynamic mode where the images are obtained by scanning. The method acts by dividing the OCT image into different regular regions, calculating different texture features for each of the above regions with a reduced set of less than a full set of the 26 Haralick textural features, using a clustering algorithm to segment the image defined by its texture features calculated above into different regions and transforming the segmented image back from its representation using texture features to its space-domain representation. The method uses three or four texture features where the reduced sets can be f1, f 2, and f14 (ASM at 0°, Inertia at 0° and ASM at 90°).
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: January 26, 2021
    Assignee: University of Manitoba
    Inventors: Ammu Prakash, Sherif S. Sherif
  • Patent number: 10882822
    Abstract: The present disclosure relates to using a compound as a reactant in one or more chemical reactions for making intermediate compounds or reaction-product compounds that includes at least one cyclic N-halamine precursor group and at least one cationic center. The compound has the general formula (1): Wherein Z is either N or Y and when Z is N then R1 and R2 are each independently selected from a group of methyl, ethyl or n-propyl. When Z is Y then R1 and R2 are both nil and Y is selected from Cl, Br and I. The reaction-product compound may have biocidal activity and/or it may have increased biocidal activity following one or more chemical-modification reactions.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: January 5, 2021
    Assignee: UNIVERSITY OF MANITOBA
    Inventor: Gurmeet S. Bindra
  • Patent number: 10830665
    Abstract: A low cost and efficient damage detection method is developed by introducing a new piezoelectric composite coating combined with a self-powered wireless signal transmission module. The new piezoelectric composite coating composed with a piezoelectric layer, an electrical conductive layer and an insulator, is designed as the sensor and to be easily applied on rough surfaces of engineering structures, such as concrete and the welded joint area. An energy harvesting circuit and an automatic electronic switch controlled by the piezoelectric coating sensor are designed to power and control the wireless signal transmitter sending warning signals of the damage occurrence. Methodology is explained in detail, and successful detection of the occurrence of crack propagation on a beam structure has been realized through experimental testing.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: November 10, 2020
    Assignee: University of Manitoba
    Inventors: Nan Wu, Farjana Faisal, Samuel Osho
  • Patent number: 10814397
    Abstract: A method for synthesizing a reagent complex includes a step of ball-milling a mixture that includes: a powder of a zero-valent element; a hydride molecule; and a nitrile ligand. The method produces a reagent complex having a formula Q0.Xy.Lz, where Q0 is the zero-valent element, X is the hydride molecule, and L is the nitrile ligand. A process for synthesizing nanoparticles composed of the zero-valent element includes a step of adding solvent to the reagent complex. Crystal texture of the nanoparticles is modulated by appropriate selection of the molar ratio nitrile ligand in the reagent complex.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: October 27, 2020
    Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., The University of Manitoba
    Inventors: Elizabeth Marie Skoropata, Michael Paul Rowe, Johan Alexander van Lierop
  • Patent number: 10728981
    Abstract: Low cost and low power LED lamps exhibit current harmonic contents due to their nonlinear characteristics. A large scale lighting network requires tens to hundreds LED lamp installations, the resultant harmonic currents pollute the grid seriously. Furthermore, light intensity fluctuations are becoming a concern nowadays to many users, as a safety and a health problems. This phenomenon is mainly caused by heavy loads as they lead to voltage fluctuations and deteriorating in PQ and hence visual flickering in LED lamps. A single phase transformer-less unified power quality conditioner (UPQC) topology is provided with its controls to mitigate all PQ problems in a network.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: July 28, 2020
    Assignee: University of Manitoba
    Inventors: Ngai Man Ho, Radwa Abdalaal, Henry Shu Hung Chung
  • Patent number: 10716488
    Abstract: Exemplary methods and systems may image an object of interest using one or more waveguide assemblies including gated elements. The gated elements may be configurable in a transmission state, a reception state, or a passive state. The exemplary methods and systems may deliver electromagnetic energy (e.g., microwave energy) to an object of interest using a gated element of a waveguide assembly configured in a transmission state and sample scattered field using a gated element of another waveguide assembly configured in the reception state while the remainder of gated elements are configured in the passive state.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: July 21, 2020
    Assignee: The University of Manitoba
    Inventors: Majid Ostadrahimi, Joe Lovetri
  • Patent number: 10693393
    Abstract: A new tri-electrode topology reduces the control voltage requirement for electrostatic actuators. Conventional parallel plate actuators are dual-electrode systems, formed by the MEMS structure and the drive electrode. By placing a perforated intermediate electrode between these elements, a tri-electrode configuration is formed. This topology enables a low voltage on the intermediate electrode to modulate the electrostatic force of the higher voltage drive electrode, whose voltage remains fixed. Results presented show that in comparison to conventional parallel plate electrostatic actuators, the intermediate electrode's modulating voltage can be as low as 20% of normal, while still providing the full actuation stroke.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: June 23, 2020
    Assignee: University of Manitoba
    Inventors: Cyrus Shafai, Yu Zhou
  • Patent number: 10438406
    Abstract: A novel methodology for computing the medial axis/skeleton of a discrete binary object using a ‘divide and conquer’ algorithm, in which any 3D object is first sliced into a series of 2D images in X, Y and Z directions. Then, a geometric (Voronoi) algorithm is applied on each 2D image to extract the respective medial axis. This information is then combined to reconstruct the medial axis of the original 3D object using an intersection technique. An optional 3D interpolation step to achieve continuous connected skeletons uses Delaunay triangles and a spherical search to establish the nearest neighboring points in 3D space to interpolate between. Test results show that the proposed 3D Voronoi and optional interpolation algorithms are able to accurately and efficiently extract medial axes for complex 3D objects as well. Finally, an axis-smoothing algorithm using the same Delaunay triangle and spherical test is operable to remove unwanted noise from the extracted medial axis.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: October 8, 2019
    Assignee: University of Manitoba
    Inventors: Sohail Younas, Chase R. Figley
  • Patent number: 10407473
    Abstract: Provided herein are FDC-SP polypeptides and methods of using such polypeptides. Methods include, but are not limited to, altering IgA concentration in a subject, treating a subject having signs of a disorder that includes excessive IgA production, identifying a compound that decreases the concentration of IgA in an animal, and identifying a compound that treats a condition associated with increased levels of IgA. Also provided herein is an animal that has decreased expression of an endogenous FDC-SP coding sequence. The animal may develop pathophysiological features of IgA nephropathy, and/or may display increased IgA in serum, saliva, bronchoalveolar lavage fluid, or a combination thereof; increased IgA expressing B lymphocytes in circulation, lymphoid tissue, or a combination thereof; or increased IgA production in vitro by isolated B lymphocytes.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: September 10, 2019
    Assignee: UNIVERSITY OF MANITOBA
    Inventors: Aaron Marshall, Sen Hou
  • Patent number: 10400227
    Abstract: Embodiments herein include variants of ?-hexosaminidase that are useful for hydrolyzing GM2 ganglioside, polynucleotides encoding the same, and related methods. In various embodiments, a variant ?-hexosaminidase subunit is included wherein the variant ?-hexosaminidase subunit forms a homodimer under physiological conditions and wherein the variant ?-hexosaminidase subunit associates with GM2 activator protein to hydrolyze GM2 ganglioside. In some embodiments, an isolated or recombinant polynucleotide encoding such a variant ?-hexosaminidase subunit is included. In some embodiments, a method of treating a subject exhibiting an abnormal cellular accumulation of GM2 ganglioside is included wherein the method includes administering a composition including a protein variant of ?-hexosaminidase or a polynucleotide encoding the same. Other embodiments are included herein.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: September 3, 2019
    Assignees: The University of Manitoba, The Hospital for Sick Children
    Inventors: Don Mahuran, Brian Mark
  • Patent number: 10381953
    Abstract: A bidirectional bridgeless buck-boost power converter circuit is provided that can function as both a voltage source inverter (VSI) circuit to transform direct current (DC) voltage to alternating current (AC) voltage and as a power factor corrector (PFC) circuit to transform AC voltage to DC voltage. The disclosed converter fully utilizes inductors to form a CL filter and buck-boost converter energy storage element. Thus, low inductance chokes are used in the converter, which leads to a higher power density and is more cost-effective. Further, the bridgeless configuration minimizes conduction losses of semiconductors, and coupled with the use of low inductance chokes this improves system efficiency.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: August 13, 2019
    Assignee: The University of Manitoba
    Inventors: Ngai Man Ho, King Man Siu
  • Patent number: 10331813
    Abstract: A method and system for performing closed loop simulation of a computer model of a physical system and a hardware component of the physical system is provided. An input waveform for the component from the simulated model of the physical system using an initial waveform as a response waveform of the component is generated at a simulation processor. The input waveform is sent from the simulation processor through a network to a real-time playback and record device (RTPR). The RTPR plays back the input waveform in real time to the component and receives a response waveform of the component and provides the response waveform to the simulation processor. Waveform relaxation (WR) converging methods are utilized at the simulation processor to enable convergence of the generated waveforms affected by hardware induced distortions. A WR method with the generated waveforms are performed to provide a closed loop response of the component.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: June 25, 2019
    Assignee: THE UNIVERSITY OF MANITOBA
    Inventors: Mohammad Goulkhah, Aniruddha Madhukar Gole
  • Patent number: 10307428
    Abstract: Compositions for therapy of a diabetic symmetrical polyneuropathy a subject in need thereof, the compositions comprising: an effective amount of a muscarinic acetylcholine receptor antagonist exemplified by pirenzepine, telenzepine, atropine, or derivatives thereof or salts thereof or analogs thereof or derivatives thereof, and a pharmacologically acceptable carrier. The composition may be injectable or alternatively, may be applied topically or alternatively, may be delivered orally. A suitable topical composition may comprise a lotion, a cream, a gel, or a viscous fluid. The muscarinic acetylcholine receptor antagonist may be a muscarinic acetylcholine receptor antagonist salt or a muscarinic acetylcholine receptor antagonist derivative or a muscarinic acetylcholine receptor antagonist analog.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: June 4, 2019
    Assignees: University Health Network, University of Manitoba, The Regents of The University of California
    Inventors: Paul Fernyhough, Nigel A. Calcutt, Lakshmi Kotra
  • Patent number: 10281511
    Abstract: A new passive wireless electric field sensor is disclosed. This sensor does not require direct attachment to a source of power which makes it passive. It is composed of a resonator loaded with varactors. The sensor is interrogated by a remotely located device transmitting and receiving the pulses of sine wave in the resonance frequency range of the sensor. Therefore, the sensor can be mounted in the vicinity of high voltage apparatus and interrogated from a safe distance.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: May 7, 2019
    Assignee: The University of Manitoba
    Inventors: Mana Yazdani, Behzad Kordi, Douglas J. Thomson
  • Patent number: 10254249
    Abstract: A method to predict the catalytic activity of a metal oxide of formula MxOy where x is a number from 1 to 3 and y is a number from 1 to 8 is provided. The metal of the metal oxide has redox coupled oxidation states wherein the redox transformation is between oxidation states selected from the group consisting of a diamagnetic oxidation state (Md+) and a paramagnetic oxidation state (Mp+), a paramagnetic oxidation state (Mp+) and a ferromagnetic oxidation state (Mf+), and a paramagnetic oxidation state (Mp+) and an antiferromagnetic oxidation state (Ma+)where d, p, f and a are independently numbers from 1 to 6 and one of the oxidation states (Md+), (Mp+), (Mf+), and (Ma+) is formed by reduction by the O2?. The magnetic susceptibility of the metal oxide as a sample in an oxygen environment at a specified temperature is correlated with a value of (Md+ or Mp+ or Mf+ or Ma+)/g (O2 rich).
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: April 9, 2019
    Assignees: The University of Manitoba, Toyota Motor Engineering & Manufacturing North America, Inc.
    Inventors: Vinod K. Paidi, Johan A. Van Lierop, Charles A. Roberts
  • Publication number: 20190017964
    Abstract: A method to predict the catalytic activity of a metal oxide of formula MxOy where x is a number from 1 to 3 and y is a number from 1 to 8 is provided. The metal of the metal oxide has redox coupled oxidation states wherein the redox transformation is between oxidation states selected from the group consisting of a diamagnetic oxidation state (Md+) and a paramagnetic oxidation state (Mp+), a paramagnetic oxidation state (Mp+) and a ferromagnetic oxidation state (Mf+), and a paramagnetic oxidation state (Mp+) and an antiferromagnetic oxidation state (Ma+)where d, p, f and a are independently numbers from 1 to 6 and one of the oxidation states (Md+), (Mp+), (Mf+), and (Ma+) is formed by reduction by the O2?. The magnetic susceptibility of the metal oxide as a sample in an oxygen environment at a specified temperature is correlated with a value of (Md+ or Mp+ or Mf+ or Ma+)/g (O2 rich).
    Type: Application
    Filed: July 11, 2017
    Publication date: January 17, 2019
    Applicants: The University of Manitoba, Toyota Motor Engineering & Manufacturing North America, Inc.
    Inventors: Vinod K. PAIDI, Johan A. VAN LIEROP, Charles A. ROBERTS
  • Patent number: 10174440
    Abstract: Textile fibers and textiles produced from Brassica plants retain properties that are favorable for textile manufacture. Also described are textiles manufactured from the textile fibers produced from the Brassica plants which exhibit properties that are favorable for apparel and domestic applications, as well as industrial applications. Methods for producing the textile fibers from Brassica plants are further described.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: January 8, 2019
    Assignee: University of Manitoba
    Inventors: Gustaaf Peter Sevenhuysen, Mashiur Rahman
  • Publication number: 20180263775
    Abstract: A two-part aortic annular support system for supporting an aortic annulus during aortic valve repair procedures for prevention of further annular dilation. The first part comprises a composite annular ring that is positionable from within an aortic valve into the left ventricular outflow tract at the level of annular plane. The composite ring comprises a semi-rigid section and a resiliently deformable section. The semi-rigid section is shorter in length than the deformable section. The deformable section is extendible into a commissure of the aortic valve. The second part is a resilient band that is positionable external to the aortic root. The resilient band is securable to the composite ring through the aortic annulus by suturing. The present disclosure also relates to a use of the aortic annular support system and a method of inserting and securing the aortic annular support system during a surgical intervention.
    Type: Application
    Filed: September 16, 2016
    Publication date: September 20, 2018
    Applicant: University of Manitoba
    Inventor: Pallav SHAH
  • Patent number: 10036742
    Abstract: The Mito-Ob obese mouse model overexpresses the mitochondrial protein prohibitin (PHB). Mito-Ob male mice develop insulin resistance in addition to obesity and they do not develop overt diabetes. It has been discovered that these mice also spontaneously develop nonalcoholic steatohepatitis (NASH) and hepatocarcinogenesis over time. Also described is a mutant Mito-Ob mouse that develops lymphadenopathy and histiocytosis.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: July 31, 2018
    Assignee: University of Manitoba
    Inventors: Sudharsana Rao Ande, Khanh Hoa Nguyen, Suresh Mishra