Patents Assigned to University of Maryland, College Park Office of Technology Commercialization
  • Publication number: 20130239308
    Abstract: A method and devices are described, in which a transformable fiber at a first crystal structure is shaped from its pre-determined configuration into a new shaped configuration. The new shaped configuration of the transformable fiber is inserted into a cavity of a heat and fire protective item. The new shaped configuration of the transformable fiber is heated to above its transformation temperature to a second crystal structure. The heating transforms the new shaped configuration to its pre-determined configuration, wherein the pre-determined configuration forms an air pocket within the heat and fire protective item. The transformable fiber is cooled below its transformation temperature to revert the transformable fiber back to the new shaped configuration at the first crystal structure.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 19, 2013
    Applicant: University of Maryland, College Park Office of Technology Commercialization
    Inventor: University of Maryland, College Park Office of Technology Commercialization
  • Patent number: 8338566
    Abstract: In this application is described the characterization Borrelia burgdorferi lipoprotein BBK07, an in vivo expressed and surface-exposed immunogen. BBK07 expression in the infected hose can be detected at the RNA and protein level as early as the first week of infection. Therefore, described is the use of BBK07 antigen and immunogenic epitopes as well as bbk07 nucleotides in methods and kits for the diagnosis of Lyme disease.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: December 25, 2012
    Assignee: University of Maryland, College Park Office of Technology Commercialization
    Inventors: Utpal Pal, Adam Steven Coleman
  • Publication number: 20120252703
    Abstract: A biosensor comprising an electrically conductive substrate coated with a modified chitosan biopolymer that has been electrodeposited on the substrate, wherein said modified chitosan biopolymer comprises at least one vesicle binding molecule. The biosensor is manufactured by a method where a modified chitosan biopolymer is electrodeposited on a substrate. The method is also used to manufacture a modified chitosan biopolymer film by electrodeposition of the chitosan on the substrate and later removing the film from the substrate after electrodeposition. The resulting film can be used in bandages to treat various types of wounds. The biosensor can also be used to detect various analytes in samples.
    Type: Application
    Filed: December 2, 2011
    Publication date: October 4, 2012
    Applicant: University of Maryland,College Park Office of Technology and Commercialization
    Inventors: Matthew Dowling, Srinivasa R. Raghavan, Neeraja Dashaputre, Douglas Stephen English, Vishal Javvaji, Gregory F. Payne, Philip R. DeShong
  • Publication number: 20110028654
    Abstract: Disclosed is a method of producing a polyolefin composition comprising contacting a metallocene pre-catalyst, co-catalyst, and a stoichiometric excess of a metal alkyl; adding a first olefin monomer; and polymerizing the first monomer for a time sufficient to form the polyolefin. The method allows for the use of minimum amounts of activating co-catalyst and metallocene pre-catalyst. Also disclosed is a method of producing a block polyolefin composition comprising contacting a metallocene pre-catalyst, a co-catalyst, and a stoichiometric excess of a metal alkyl; adding a first olefin monomer; polymerizing the first monomer for a time sufficient to form the polyolefin; adding a second monomer; and polymerizing the second olefin monomer for a time sufficient to form said block polyolefin composition. Also disclosed are amorphous atactic polymer and copolymer compositions made according to the present invention.
    Type: Application
    Filed: November 10, 2008
    Publication date: February 3, 2011
    Applicant: University of Maryland, college Park Office of Technology Commercialization
    Inventors: Lawrence R. Sita, Wei Zhang
  • Patent number: 6846804
    Abstract: A sublancin peptide variant having a Gly-His peptide sequence fused to the C-terminal end of the mature sublancin peptide provides an affinity tag facilitating increased purification of the peptide variant from sample preparations without affecting the intracellular processing of the sublancin peptide variant, expression by a host cell or its biological activity in secreted form. This sublancin variant has specific inhibitory activity for spore outgrowth as for the native sublancin peptide. Production of the sublancin peptide variant on an industrial scale is set forth as are methods of decontaminating spore-infected areas. Methods for generating the peptide variant gene, plasmid and transformant are also described.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: January 25, 2005
    Assignee: University of Maryland, College Park Office of Technology Commercialization
    Inventor: J. Norman Hansen
  • Patent number: 6399306
    Abstract: Methods of reducing blood pressure levels in hypertensive subjects through the identification of subjects with an allele and/or genotype at a gene locus that positively correlates with improved success in reducing blood pressure levels, as compared to other alleles and/or genotypes at the same gene locus, and through the engagement of these subjects in exercise training for a period of time sufficient for the reduction of the subjects' blood pressure levels.
    Type: Grant
    Filed: September 5, 2000
    Date of Patent: June 4, 2002
    Assignee: University of Maryland, College Park Office of Technology Commercialization
    Inventors: James M. Hagberg, Robert E. Ferrell, Michael D. Brown