Abstract: The present invention provides methods for detecting and treating cancer. In some embodiments, levels of ISG15 are determined, and topoisomerase I and II inhibitors as well as other DNA-damaging agents plus agents that increase the expression of ISG15 are selected and administered.
Type:
Application
Filed:
March 17, 2008
Publication date:
May 6, 2010
Applicant:
University of Medicine and Dentistry of New Jresey
Inventors:
Leroy F. Liu, Shyamal Desai, Johnson Yin-Nam Lau