Abstract: The present invention generally relates to articles comprising microstructures and methods for forming microstructures. The microstructures may be mechanically coupled to impart complex three dimensional shapes. For example, one or more microstructures may be grown on a substrate at different average growth rates, resulting in curved microstructures.
Type:
Application
Filed:
July 28, 2014
Publication date:
January 28, 2016
Applicants:
Massachusetts Institute of Technology, University of Michigan, The Board of Regents Acting For and On Behalf of the C/O Technology Man
Inventors:
Anastasios John Hart, Sei Jin Park, Sameh Hani Tawfick, Michael FI De Volder
Abstract: The present invention relates to the formation and processing of nanostructures including nanotubes. Some embodiments provide processes for nanostructure growth using relatively mild conditions (e.g., low temperatures). In some cases, methods of the invention may improve the efficiency (e.g., catalyst efficiency) of nanostructure formation and may reduce the production of undesired byproducts during nanostructure formation, including volatile organic compounds and/or polycylic aromatic hydrocarbons. Such methods can both reduce the costs associated with nanostructure formation, as well as reduce the harmful effects of nanostructure fabrication on environmental and public health and safety.
Type:
Grant
Filed:
June 17, 2010
Date of Patent:
October 1, 2013
Assignees:
Massachusetts Institute of Technology, University of Michigan, The Board of Regents Acting For and On Behalf of the C/O Technology Management Office, Woods Hole Oceanographic Institute
Inventors:
Desiree L. Plata, Philip S. Gschwend, Anastasios John Hart, Eric R. Meshot, Christopher M. Reddy
Abstract: The present invention relates to the formation and processing of nanostructures including nanotubes. Some embodiments provide processes for nanostructure growth using relatively mild conditions (e.g., low temperatures). In some cases, methods of the invention may improve the efficiency (e.g., catalyst efficiency) of nanostructure formation and may reduce the production of undesired byproducts during nanostructure formation, including volatile organic compounds and/or polycylic aromatic hydrocarbons. Such methods can both reduce the costs associated with nanostructure formation, as well as reduce the harmful effects of nanostructure fabrication on environmental and public health and safety.
Type:
Application
Filed:
June 17, 2010
Publication date:
February 17, 2011
Applicants:
Massachusetts Institute of Technology, University of Michigan, The Board of Regents Acting For and On Behalf of the C/O Technology, Woods Hole Oceanographic Institute
Inventors:
Desiree L. Plata, Philip M. Gschwend, Anastasios John Hart, Eric R. Meshot, Christopher M. Reddy
Abstract: Less toxic agents for reversal of heparin or low molecular weight heparin anticoagulation which are synthetic protamine-like polycationic peptides having a total cationic charge which is less than that of n-protamine. In preferred embodiments, arginine residues of n-protamine are replaced with lysine residues for ease of manufacture. Selective positively charged arginine residues have been replaced with an uncharged amino acid residue or its analog, such as glycine or glutamine, in order to reduce the total cationic charge on the polycationic peptide to the range of about [+14] to [+18], preferably [+16] to [+18]. In specific embodiments, there are sequences of 29 and 32 amino acid residues wherein 4 to 5 clusters of 2 to 4 positively charged amino acids are separated by 2 to 6 neutral amino acids. The C-terminus and the N-terminus can be modified to mitigate against in vivo degradation by carboxypeptidases and aminopeptidases. Another modification, specifically use of .alpha.
Type:
Grant
Filed:
September 8, 1994
Date of Patent:
March 25, 1997
Assignee:
University of Michigan, The Board of Regents Acting For and on Behalf of
Inventors:
Thomas W. Wakefield, James C. Stanley, Philip C. Andrews