Patents Assigned to University of Minnesota
  • Patent number: 11561192
    Abstract: An electrical device includes at least one graphene quantum capacitance varactor. In some examples, the graphene quantum capacitance varactor includes an insulator layer, a graphene layer disposed on the insulator layer, a dielectric layer disposed on the graphene layer, a gate electrode formed on the dielectric layer, and at least one contact electrode disposed on the graphene layer and making electrical contact with the graphene layer. In other examples, the graphene quantum capacitance varactor includes an insulator layer, a gate electrode recessed in the insulator layer, a dielectric layer formed on the gate electrode, a graphene layer formed on the dielectric layer, wherein the graphene layer comprises an exposed surface opposite the dielectric layer, and at least one contact electrode formed on the graphene layer and making electrical contact with the graphene layer.
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: January 24, 2023
    Assignee: Regents of the University of Minnesota
    Inventor: Steven J. Koester
  • Patent number: 11560432
    Abstract: Phycoerythrin (PE) and peptide:MHCII (p:MHCII) reactive monoclonal antibodies; methods to generate monoclonal antibodies including, for example, peptide:MHC (p:MHC) reactive monoclonal antibodies; compositions including monoclonal antibodies; and uses thereof.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: January 24, 2023
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Brian T. Fife, Justin A. Spanier, Marc K. Jenkins, Justin J. Taylor
  • Patent number: 11548789
    Abstract: The present disclosure relates to systems and methods of making ammonia using stable ammonia absorbents. The system and method for producing ammonia, comprises a reactor comprising a catalyst that converts at least a portion of nitrogen feed gas and at least a portion of hydrogen feed gas to ammonia (NH3) forming a reaction mixture comprising the ammonia, unreacted nitrogen, and unreacted hydrogen. An absorber configured to selectively absorb ammonia from the reaction mixture at a temperature of about 180 deg. C. to 330 deg. C. and a pressure of about 1-20 bar, the absorber comprising a solid absorbent. Preferably the solid absorbent is at least one metal halide and a solid support. The unabsorbed ammonium, the unreacted nitrogen, and unreacted hydrogen gas are recycled to the reactor.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: January 10, 2023
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Edward Cussler, Alon McCormick, Mohammadmahdi Malmali
  • Patent number: 11552242
    Abstract: In some examples, a device includes a magnetic tunnel junction including a first Weyl semimetal layer, a second Weyl semimetal layer, and a dielectric layer positioned between the first and second Weyl semimetal layers. The magnetic tunnel junction may have a large tunnel magnetoresistance ratio, which may be greater than five hundred percent or even greater than one thousand percent.
    Type: Grant
    Filed: April 8, 2021
    Date of Patent: January 10, 2023
    Assignee: Regents of the University of Minnesota
    Inventors: Duarte José Pereira de Sousa, Cesar Octavio Ascencio, Jian-Ping Wang, Tony Low
  • Patent number: 11547384
    Abstract: Ultrasound methods provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both wall motion and flow can be tracked simultaneously). Ultrasound systems provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both wall motion and flow can be tracked simultaneously).
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: January 10, 2023
    Assignee: Regents of the University of Minnesota
    Inventors: Emad S. Ebbini, Dalong Liu, Yayun Wan, Andrew J. Casper
  • Patent number: 11540874
    Abstract: The present disclosure relates to methods, devices, kits and systems for enhancing the efficacy and longevity of denervation procedures.
    Type: Grant
    Filed: April 30, 2020
    Date of Patent: January 3, 2023
    Assignees: Boston Scientific Scimed, Inc., Regents of the University of Minnesota
    Inventors: Bryan Allen Clark, Akshay Ashok Gupte, Bryce Calvin Beverlin, II, David Ernest Wechter, Kate Taylor
  • Patent number: 11542410
    Abstract: Bioactive coatings that are stabilized against inactivation by weathering are provided including a base including an enzyme associated therein, and a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: January 3, 2023
    Assignees: Toyota Motor Corporation, Regents of the University of Minnesota
    Inventors: Hongfei Jia, Ping Wang, Liting Zhang, Andreas Buthe, Xueyan Zhao, Songtao Wu, Masahiko Ishii, Minjuan Zhang
  • Patent number: 11543475
    Abstract: An antenna apparatus for a radio frequency (RF) coil to transmit signals to and to receive signal from a subject in a magnetic resonance imaging (MRI) system includes a distal surface facing away from the subject, a proximal surface facing towards the subject, a high permittivity material (HPM) having a shape, and an antenna coupled to the HPM and positioned on the proximal surface such that the antenna is positioned between the HPM and the subject.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: January 3, 2023
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Myung Kyun Woo, Gregor Adriany, Kamil Ugurbil, Russell L. Lagore, Lance DelaBarre, Jerahmie Radder
  • Patent number: 11535773
    Abstract: Bioactive coatings suitable for facilitating removal of a fingerprint when contacting the coating are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate. Also provided are processes of facilitating fingerprint removal.
    Type: Grant
    Filed: January 26, 2019
    Date of Patent: December 27, 2022
    Assignees: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Hongfei Jia, Ping Wang, Liting Zhang, Andreas Buthe, Xueyan Zhao, Songtao Wu, Masahiko Ishii, Minjuan Zhang
  • Patent number: 11533915
    Abstract: Provided herein are genetically modified microbes. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide that includes a pheromone-responsive region. In one embodiment, the pheromone-responsive region is derived from a conjugative plasmid from a member of the genus Enterococcus spp. The pheromone-responsive region includes a pheromone-responsive promoter and an operably linked coding region encoding an antimicrobial peptide. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide that includes a promoter and an operably linked coding sequence encoding an antimicrobial peptide, where expression of the coding region is controlled by a modulator polypeptide and is altered by a modulating agent, and where the coding region encodes an antimicrobial peptide.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: December 27, 2022
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Yiannis J. Kaznessis, Katherine G. Volzing, Juan Borrero Del Pino, Gary Dunny
  • Patent number: 11529340
    Abstract: The invention provides compounds, compositions, and methods for treating pain.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: December 20, 2022
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: George Latimer Wilcox, Daniel John Bruce, Carolyn Ann Fairbanks, Philip S. Portoghese, Eyup Akgun
  • Patent number: 11533220
    Abstract: The concepts and technologies disclosed herein are directed to a network-assisted Raft consensus protocol, referred to herein as “NetRaft.” According to one aspect of the concepts and technologies disclosed herein, a system can include a plurality of servers operating in a server cluster, and a plurality of P4 switches corresponding to the plurality of servers. Each server of the plurality of servers can include a back-end that executes a complete Raft algorithm to perform leader election, log replication, and log commitment of a Raft consensus algorithm. Each P4 switch of the plurality of P4 switches can include a front-end that executes a partial Raft algorithm to perform the log replication and the log commitment of the Raft consensus algorithm. The back-end can maintain a complete state for responding to requests that cannot be fulfilled by the front-end. The requests can include read requests and/or write requests.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: December 20, 2022
    Assignees: AT&T Intellectual Property I, L.P., Regents of the University of Minnesota
    Inventors: Bo Han, Vijay Gopalakrishnan, Marco Platania, Zhi-Li Zhang, Yang Zhang
  • Publication number: 20220389465
    Abstract: Certain embodiments provide a method of reducing biuret in a urea composition, the method comprising contacting the urea composition with an isolated or purified biuret hydrolase enzyme under conditions suitable to reduce the concentration of biuret in the urea composition.
    Type: Application
    Filed: November 25, 2020
    Publication date: December 8, 2022
    Applicant: Regents of the University of Minnesota
    Inventors: Lawrence P. Wackett, Lambros J. Tassoulas, Anthony G. Dodge
  • Publication number: 20220388993
    Abstract: The invention provides a compound of formula (I): or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, wherein R1-R6 have any of the values described in the specification, as well as compositions comprising a compound of formula (I). The compounds are useful as contraceptive agents.
    Type: Application
    Filed: May 3, 2022
    Publication date: December 8, 2022
    Applicant: Regents of the University of Minnesota
    Inventors: Ingrid Gunda Georg, Narsihmulu Cheryala
  • Publication number: 20220387777
    Abstract: Aspects include systems having an intravenous fluid bag, a tubing line assembly including tubing connected to a connector and a purge valve assembly including a spike and an outer housing. The outer housing is connected to the spike and includes a receiving end portion configured to receive the connector. The purge valve assembly further has a check valve provided within the outer housing. Generally, the purge valve assembly interconnects the fluid bag to the fluid tubing assembly for removal of air from the fluid bag prior to connection to the tubing line assembly. Various methods and purge valve assemblies provide a rapid infusion system for use. The purge valve assemblies do not require the user to reinsert the connector or spike into the intravenous fluid bag, creating a sterile solution to preparing the intravenous fluid for rapid infusion while reducing the risk of air emboli.
    Type: Application
    Filed: May 19, 2022
    Publication date: December 8, 2022
    Applicant: Regents of the University of Minnesota
    Inventors: Jonathan Strutt, Vidhu Pandey
  • Publication number: 20220389209
    Abstract: A semicrystalline multiblock copolymer includes alternating blocks of semicrystalline isotactic polypropylene (iPP) and semicrystalline polyethylene (PE), having a block arrangement according to formula (I): (iPPw)p(PEx)(iPPy)m(PEz)n?? (I), wherein p is 0 or 1; m is 0 or 1; n is 0 or 1; the sum of p, m, and n is 1, 2, or 3; and the sum of w, x, y, and z is greater than or equal to 40 kg/mol, with the provisos that: when m and n are 0, the sum of w and x is greater than or equal to 140 kg/mol; and when p and n are 0, the sum of y and x is greater than or equal to 140 kg/mol. Related compositions and methods are also provided.
    Type: Application
    Filed: February 11, 2022
    Publication date: December 8, 2022
    Applicants: CORNELL UNIVERSITY, REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Geoffrey COATES, James EAGAN, Anne LAPOINTE, Frank S. BATES
  • Publication number: 20220387800
    Abstract: User-specific neurostimulation settings are efficiently determined and optimized based on an optimized set of population-based neurostimulation settings. The population data are clustered and a set of test settings for a new user are selected as settings that efficiently discriminate between the clusters. User preference of the test settings are used to map the user to a particular cluster of settings, which can be used to determine user-specific neurostimulation settings. The user-based settings can be iteratively updated and/or optimized using information from the population data, such as by using average preference score surfaces in the population data to identify and/or filter new test settings for the user.
    Type: Application
    Filed: June 8, 2022
    Publication date: December 8, 2022
    Applicant: Regents of the University of Minnesota
    Inventors: Theoden I. Netoff, Andrew Lamperski, David Darrow, Tyler Lekang, Zixi Zhao
  • Patent number: 11519729
    Abstract: Localization and navigation systems and techniques are described. An electronic device comprises a processor configured to maintain a state vector storing estimates for a position of the electronic device at poses along a trajectory within an environment along with estimates for positions for one or more features within the environment. The processor computes, from the image data, one or more constraints based on features observed from multiple poses of the electronic device along the trajectory, and computes updated state estimates for the position of the electronic device in accordance with the motion data and the one or more computed constraints without computing updated state estimates for the features for which the one or more constraints were computed.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: December 6, 2022
    Assignee: Regents of the University of Minnesota
    Inventors: Stergios I. Roumeliotis, Anastasios I. Mourikis
  • Patent number: 11510840
    Abstract: A comprehensive system for treatment of wrist joint proprioception. The system includes a manipulandum unit and a controller. The unit includes a base, a handle, a linkage assembly, and motors. The base supports a subject's forearm, and the handle is gripped by the palm. The linkage assembly connects the handle to the base, and establishes three DOFs. The motors are operatively connected to the linkage assembly. The controller is programmed to actuate, and receive feedback information from, each of the plurality of motors. Further, the controller is programmed to perform wrist proprioception assessment operations by actuating the plurality of motors to effectuate movement of the handle relative to the base in a prescribed manner indicative of position motion sense acuity as an objective measure of wrist proprioception functioning. The controller is optionally further programmed to perform rehabilitation training via controlled operation of the unit and a virtually reality environment.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: November 29, 2022
    Assignees: Regents of the University of Minnesota, Nanyang Technological University
    Inventors: Lorenzo Masia, Juergen Konczak, Giulio Sandini, Leonardo Cappello
  • Patent number: PP34794
    Abstract: The invention is a new and distinct variety of grapevine plant named ‘Clarion’ that is characterized by its grapes with a moderate juice total acidity (average of 7.73 g/L) making it suitable for wine production, its grapes that lack less desirable aromatic compounds that are typical of cold climate hybrid grapes, its grapes with floral notes including lilac and tropical fruit notes, its good growth habit without excessive vigor, and its grapes with a loose cluster architecture.
    Type: Grant
    Filed: February 2, 2022
    Date of Patent: December 6, 2022
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Matthew D. Clark, James Luby, Peter Hemstad