Patents Assigned to UNIVERSITY OF MISSOURI, OFFICE OF IPA
  • Patent number: 9771577
    Abstract: The present invention relates to compositions and methods useful for analyzing lariat RNA, which plays a role in the regulation of gene expression. A sample of RNA is specifically treated to remove linear mRNA and enrich for lariat RNA. The enriched lariat RNA sample may be analyzed further to identify introns, branch point sequences, alternative splicing patters, and gene transcription levels. The enriched lariat RNA sample may also be exploited as a detection or compound screening tool, as well as other uses.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: September 26, 2017
    Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI UNIVERSITY OF MISSOURI, OFFICE OF IPA
    Inventor: Thomas Matthew Menees
  • Publication number: 20120070466
    Abstract: Disclosed are compositions comprising collagen covalently bound to particles, wherein covalent bonds are formed between reactive groups of the collagen and reactive groups of the particles, and wherein the particles have an average particle diameter ranging from 20 to 1000 nanometers. Also disclosed are various methods that utilize the compositions.
    Type: Application
    Filed: June 7, 2011
    Publication date: March 22, 2012
    Applicant: UNIVERSITY OF MISSOURI, OFFICE OF IPA
    Inventors: Anthony Harris, Jonathan Thompson, Rebecca Rone, Sheila Grant, David Grant