Patents Assigned to University of Mount Sinai School of Medicine of the City of New York
  • Treatment of neurodegenerative conditions with nimesulide
    Patent number: 7226948
    Abstract: The present invention relates to the use of nimesulide and structurally related compounds in the prevention and/or treatment of neurodegenerative conditions. It is based, at least in part, on the discovery that nimesulide exhibits a neuroprotective effect against ?-amyloid induced cell death. Without being bound to any particular theory, it appears that nimesulide inhibits a non-inflammatory mechanism of neurodegeneration.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: June 5, 2007
    Assignee: University of Mount Sinai School of Medicine of the City of New York
    Inventors: Giulio M. Pasinetti, Paul S. Aisen