Abstract: The present disclosure provides, among other things, compounds and crystalline forms of compounds thereof and methods of making and using such compounds and crystalline forms of compounds. Disclosed compounds and crystalline forms are useful in electronic materials, semiconductor materials, and optoelectronic materials and devices incorporating these materials and which exhibit desirable characteristics for the same.

Abstract: This invention is directed to transition metal-based-halloysite nanocomposites and methods of making and using the same.

Abstract: Pneumonia due to the fungus Pneumocystis jirovecii is a life-threatening infection that occurs in immunocompromised patients. The inability to culture the organism as well as the lack of a sequenced genome has hindered antigen discovery that could be useful in developing effective vaccines, therapeutic antibodies and diagnostic methods. A method of surface proteomics of Pneumocystis murina that reliably detects surface proteins that are conserved in Pneumocystis jirovecii is described. In particular, eight identified P. murina surface proteins are described. Methods of eliciting immune responses against the identified proteins, generating therapeutic antibodies against the identified proteins, as well as diagnostic methods based on the identified peptides are described.

Abstract: A surface protein of the murine fungal pathogen Pneumocystis murina can be used to generate an immune response in a recipient animal or human that provides prophylactic protection and an anti-fungal activity in subjects already infected with a Pneumocystis species. Further, the disclosure provides novel polypeptides or peptides derived from the P. murina surface protein Surface Peptidase 1 (SPD-1) that are useful, alone or in combination with the SPD-1 polypeptide, in compositions and methods for the generation of an anti-Pneumocystis immune reaction by a recipient subject. The compositions and methods of the disclosure provide advantageous alternatives to available immunogenic determinants for the treatment or prevention of fungal pneumonia.

Abstract: Pneumonia due to the fungus Pneumocystis jirovecii is a life-threatening infection that occurs in immunocompromised patients. The inability to culture the organism as well as the lack of a sequenced genome has hindered antigen discovery that could be useful in developing effective vaccines, therapeutic antibodies and diagnostic methods. A method of surface proteomics of Pneumocystis murina that reliably detects surface proteins that are conserved in Pneumocystis jirovecii is described. In particular, eight identified P. murina surface proteins are described. Methods of eliciting immune responses against the identified proteins, generating therapeutic antibodies against the identified proteins, as well as diagnostic methods based on the identified peptides are described.

Abstract: One exemplary embodiment of this invention provides a single-effect absorption chiller including an absorber operatively connected to a solution heat exchanger and a generator, and a condenser in fluid communication with the absorber, wherein the absorber is sized and configured to receive a feed of water from a source of water and to transfer heat to the feed of water and then to convey the feed of water to the condenser without further heat conditioning of the feed of water prior to its entry into the condenser, and wherein the condenser is sized and configured to receive the feed of water from the absorber and to transfer heat to the feed of water, thereby cooling the condenser without resorting to an external heat exchanger such as a conventional cooling tower.

Abstract: Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the antimicrobial agent, methods of treatment of an infection, methods of treatment using compositions or pharmaceutical compositions, and the like.

Abstract: A thermoelectric metamaterial is provided, comprising a plurality of component materials selected from the group consisting of dielectrics, semiconductors, semimetals, and metals. The component materials are placed into contact with one another and arranged in a selected geometrical configuration adapted to achieve a thermal conductivity of the metamaterial that is different from the thermal conductivity of each of the component materials. Specifically, the component materials are arranged to affect an increase in the figure of merit and power conversion efficiency of the metamaterial.

Abstract: One exemplary embodiment of this invention provides a single-effect absorption chiller including an absorber operatively connected to a solution heat exchanger and a generator, and a condenser in fluid communication with the absorber, wherein the absorber is sized and configured to receive a feed of water from a source of water and to transfer heat to the feed of water and then to convey the feed of water to the condenser without further heat conditioning of the feed of water prior to its entry into the condenser, and wherein the condenser is sized and configured to receive the feed of water from the absorber and to transfer heat to the feed of water, thereby cooling the condenser without resorting to an external heat exchanger such as a conventional cooling tower.

Abstract: One exemplary embodiment of this invention provides a single-effect absorption chiller including an absorber operatively connected to a solution heat exchanger and a generator, and a condenser in fluid communication with the absorber, wherein the absorber is sized and configured to receive a feed of water from a source of water and to transfer heat to the feed of water and then to convey the feed of water to the condenser without further heat conditioning of the feed of water prior to its entry into the condenser, and wherein the condenser is sized and configured to receive the feed of water from the absorber and to transfer heat to the feed of water, thereby cooling the condenser without resorting to an external heat exchanger such as a conventional cooling tower.

Abstract: Apparatus and methods for fabricating nanofibers by reactive electrospinning are described. An electrospinning process is coupled with an in-line reactor where chemical or photochemical reactions take place. This invention expands the application of the electrospinning and allows the production of nanofibers of crosslinked polymers and other new materials, such as gel nanofibers of ceramic precursors.

Abstract: A number of cationic gold(I) and neutral gold(III) complexes have been synthesized and found to be stabilized by the use of N-heterocyclic carbene ligands. These species are often employed as in situ-generated reactive intermediates in gold catalyzed organic transformations. An isolated, well-defined cationic species was tested in gold mediated carbene transfer reactions from ethyl diazoacetate.

Abstract: Negatively charged luminescent CdSe—ZnS quantum dots (QDs) were successfully incorporated into novel luminescent glyconanospheres averaging around 190 nm in diameter through electrostatic interactions with carboxymethyldextran (CM-dextran) and polylysine. The glyconanospheres preferably contain as well carboxyl-modified iron oxide nanocrystals. In addition to electrostatic attraction between the negatively charged dextran, the negatively charged CdSe—ZnS QDs (and negatively charged iron oxide nanocrystals, if present), and the positively charged polylysine, covalent amide bonds were introduced to cross link the QDs (and negatively charged iron oxide nanocrystals, if present) with the polysaccharide matrix to further stabilize the glyconanospheres. The dextran residues on the surface of the nanospheres show high affinity toward the glucose binding protein-Concanavalin A (Con A).

Abstract: Catalytic complexes including a metal atom having anionic ligands, at least one nucleophilic carbine ligand, and an alkylidene, vinylidene, or allenylidene ligand. The complexes are highly stable to air, moisture and thermal degradation. The complexes are designed to efficiently carry out a variety of olefin metathesis reactions.

Abstract: One exemplary embodiment of this invention provides a single-effect absorption chiller including an absorber operatively connected to a solution heat exchanger and a generator, and a condenser in fluid communication with the absorber, wherein the absorber is sized and configured to receive a feed of water from a source of water and to transfer heat to the feed of water and then to convey the feed of water to the condenser without further heat conditioning of the feed of water prior to its entry into the condenser, and wherein the condenser is sized and configured to receive the feed of water from the absorber and to transfer heat to the feed of water, thereby cooling the condenser without resorting to an external heat exchanger such as a conventional cooling tower.

Abstract: Negatively charged luminescent CdSe—ZnS quantum dots (QDs) were successfully incorporated into novel luminescent glyconanospheres averaging around 190 nm in diameter through electrostatic interactions with carboxymethyldextran (CM-dextran) and polylysine. The glyconanospheres preferably contain as well carboxyl-modified iron oxide nanocrystals. In addition to electrostatic attraction between the negatively charged dextran, the negatively charged CdSe—ZnS QDs (and negatively charged iron oxide nanocrystals, if present), and the positively charged polylysine, covalent amide bonds were introduced to cross link the QDs (and negatively charged iron oxide nanocrystals, if present) with the polysaccharide matrix to further stabilize the glyconanospheres. The dextran residues on the surface of the nanospheres show high affinity toward the glucose binding protein-Concanavalin A (Con A).

Abstract: This invention provides compositions which are 1,3-oxazinan-2-one compounds of formulae (I) and (II), and oxazolidinone compounds of formula (III): wherein R is a hydrocarbyl group, a heterocyclic group, a hydrocarbyl group having at least one substituent, or a heterocyclic group having at least one hydrocarbyl substituent, wherein the substituent on the hydrocarbyl group or heterocyclic group is selected from the group consisting of a heterocyclic group, an azo group, a cyano group, a nitro group, a fluoro group, a chloro group, a bromo group, an alkoxy group having up to 15 carbon atoms, and a hydrocarbyl group having up to 15 carbon atoms; and R? and R? are each independently hydrogen, an alkyl group, an aryl group, a methylaryl group, a carbonyl group, a hydrocarbylamido group, a sulfonyl group, a sulfonamoyl group, a heterocyclic group, a heterocyclic group having at least one substituent, or an aryl group or methylaryl group having at least one substituent, where the substituent on the heterocyclic grou

Abstract: Catalytic complexes including a metal atom having anionic ligands, at least one nucleophilic carbene ligand, and an alkylidene, vinylidene, or allenylidene ligand. The complexes are highly stable to air, moisture and thermal degradation. The complexes are designed to efficiently carry out a variety of olefin metathesis reactions.

Abstract: Analytical tools and methods employing processing of channel current blockade measurements to detect or assess changes in environmental conditions generally, and more specifically, to detect and assess interactions between a blockade-producing auxiliary molecule in the channel and either the surrounding conductive medium generally or molecules in that conductive medium. The auxiliary molecule is disposed within the channel in order to generate a highly structured channel current blockade signal. The blockade signal resulting from inducing ionic current flow through the channel with auxiliary molecule present, is based on an auxiliary molecule chosen to be highly susceptible to modulation when the auxiliary molecule interacts with other molecules in the surrounding conductive medium, or when it otherwise is modified or affected at the molecular level by changes in the physical or chemical conditions of that surrounding medium.

Abstract: This invention provides compositions which are 1,3-oxazinan-2-one compounds of formulae (I) and (II), and oxazolidinone compounds of formula (III): wherein R is a hydrocarbyl group, a heterocyclic group, a hydrocarbyl group having at least one substituent, or a heterocyclic group having at least one hydrocarbyl substituent, wherein the substituent on the hydrocarbyl group or heterocyclic group is selected from the group consisting of a heterocyclic group, an azo group, a cyano group, a nitro group, a fluoro group, a chloro group, a bromo group, an alkoxy group having up to 15 carbon atoms, and a hydrocarbyl group having up to 15 carbon atoms; and R? and R? are each independently hydrogen, an alkyl group, an aryl group, a methylaryl group, a carbonyl group, a hydrocarbylamido group, a sulfonyl group, a sulfonamoyl group, a heterocyclic group, a heterocyclic group having at least one substituent, or an aryl group or methylaryl group having at least one substituent, where the substituent on the heterocyclic grou