Patents Assigned to University of New York
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Patent number: 12366574Abstract: The current disclosure provides methods for detecting and analyzing K17 expression in a bladder sample obtained from a subject. The current disclosure also pertains to methods and kits for identifying a mammalian subject with bladder cancer by detecting the expression of K17 in a sample. The present methods include both cell-based and cell-free methods for determining the level of keratin 17 in a sample obtained from the bladder of a subject.Type: GrantFiled: May 27, 2022Date of Patent: July 22, 2025Assignees: The Research Foundation for The State University of New York, KDx Diagnostics, Inc.Inventors: Kenneth R. Shroyer, Luisa F. Escobar-Hoyos, Nam Kim
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Patent number: 12365592Abstract: Provided are methods for transferring graphene from graphene-on-metal foil onto a substrate. The method does not require chemical etching to remove the metal foil and provides more a uniform graphene with improved electronic properties. The present invention also provides compositions comprising graphene, a binder, and a substrate.Type: GrantFiled: November 29, 2019Date of Patent: July 22, 2025Assignee: The Research Foundation for The State University of New YorkInventors: Matthew Eisaman, Jan Folkson, Joseph Andrade
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Patent number: 12362279Abstract: Semiconducting devices, and more specifically back end of line (BEOL) portions for semiconducting devices that may include dielectric materials incorporating deuterium are disclosed. The semiconducting devices may include a back end of line (BEOL) portion electrically coupled to a front end of line (FEOL) portion. The BEOL portion may include at least one BEOL level having a dielectric layer. The dielectric layer may include at least one section formed from a low-k material including deuterium (D). The BEOL level(s) may also include an etch stop layer disposed over the dielectric layer, and at least one conductive structure disposed within the dielectric layer. The at least one conductive structure may extend through the dielectric layer and the etch stop layer, respectively.Type: GrantFiled: August 3, 2020Date of Patent: July 15, 2025Assignee: The Research Foundation for the State University of New YorkInventors: Patrick Lenahan, James Lloyd, Niaz Mahmud
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Publication number: 20250222143Abstract: The present invention provides a compound having the structure: and methods of using the compound in targeted PET and SPECT imaging.Type: ApplicationFiled: October 19, 2022Publication date: July 10, 2025Applicant: The Research Foundation for the State University of New YorkInventors: Eszter BOROS, Brett VAUGHN, Jennifer WHETTER
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Patent number: 12338184Abstract: Provided are ceramic foams. The ceramic foams may have a hierarchical pore gradient. The ceramic foams may be silica aerogels. The ceramic foams may be made by reaction of one or more precursors in the presence of an inert gas generated by a pore-forming gas-forming additive. The ceramic foams may be used as insulating materials.Type: GrantFiled: January 13, 2020Date of Patent: June 24, 2025Assignee: The Research Foundation for The State University of New YorkInventors: Shenqiang Ren, Ruizhe Yang, Binbo Chai, Feng Hu
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Patent number: 12329042Abstract: The present disclosure describes electron-photon and electron-phonon interactions in 2D material systems. In some embodiments, novel entangled states are implemented. Such entangled states may involve the superposition of electronic and phononic modes in these materials. The states may be utilized to realize the transduction of quantum information and sensing. In an aspect, the present disclosure may be a quantum sensor having a single-phonon emitter configured to emit a single phonon. A phononic transducer is configured to receive the emitted single phonon from the single-phonon emitter and propagate the single phonon. A phonon detector is configured to detect an arrival of the propagated single phonon received from the phononic transducer.Type: GrantFiled: January 26, 2022Date of Patent: June 10, 2025Assignee: The Research Foundation for The State University of New YorkInventors: Vasili Perebeinos, Jonathan P. Bird, Huamin Li
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Patent number: 12319913Abstract: The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression and tumorigenesis. As such, the present disclosure provides various nucleic acid (e.g., microRNA) compositions having 5-halouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same.Type: GrantFiled: November 24, 2021Date of Patent: June 3, 2025Assignee: The Research Foundation for The State University of New YorkInventors: Jingfang Ju, Andrew Fesler, Younghwa Song, Jun Chung
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Patent number: 12318463Abstract: Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.Type: GrantFiled: February 24, 2023Date of Patent: June 3, 2025Assignee: The Research Foundation For The State University Of New YorkInventors: Marvin Cohen, Susanne Cohen, Robert Flynn
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Publication number: 20250170277Abstract: The present disclosure provides methods of treating a human having a disease or disorder that would benefit from increasing platelet counts. The method involves inhibiting the enzyme activity of biliverdin IX? reductase (BLVRB) activity or inhibiting the expression of BLVRB gene.Type: ApplicationFiled: February 5, 2025Publication date: May 29, 2025Applicant: The Research Foundation for The State University of New YorkInventors: Wadie F. BAHOU, Song WU
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Patent number: 12316352Abstract: A system and method for concurrent encryption and lossless compression of data with an algorithm executing on a computer platform. The lossless compression component of the algorithm consists of preprocessing the data with a Burrows-Wheeler transformation followed by an inversion ranking transformation in advance of employing an entropy coder, such as binary arithmetic coder. The frequency vector of the Inversion Ranking transformation is then encrypted and transmitted along with the compressed data with only the frequency vector encrypted. Since the frequency vector is required for decompression, no further encryption of the compressed data is necessary to secure the compressed file.Type: GrantFiled: March 9, 2023Date of Patent: May 27, 2025Assignee: The Research Foundation for the State University of New YorkInventors: Ziya Arnavut, Basar Koc, Hüseyin Koçak
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Publication number: 20250154212Abstract: Provided is a method of disrupting memory, including administering to a subject a peptide, wherein the peptide prevents biding of kidney and brain expressed protein to protein kinase M zeta. Administering may include administering to a subject in need of treatment for an addition, neuropathic pain, or an anxiety disorder. The peptide may include amino acid sequence of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, OR SEQ ID NO: 6. Also provided is a lipopeptide including the amino acid sequence and a fatty acyl group selected from a C12 to a C18 fatty acid.Type: ApplicationFiled: November 8, 2024Publication date: May 15, 2025Applicant: The Research Foundation for The State University of New YorkInventor: Todd C. SACKTOR
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Patent number: 12300033Abstract: Methods and systems for identifying persons utilizing a camera and a wireless transceiver. The wireless transceiver receives wireless packets (e.g., Wi-Fi packets) from one or more mobile devices associated with one or more persons. The channel state information (CSI) is determined based on signals associated with the packets, and first motion characteristics are determined based on the CSI data. Congruently, the camera generates images, and associated image data is received, wherein the image data is associated with the one or more persons. Second motion characteristics are determined based on the image data. The first motion characteristics are matched with the second motion characteristics along with a quantified uncertainty, and the matched motion characteristics are assigned with weights that are based on the second motion characteristics (e.g., image-based). The one or more persons are identified based on the matched motion characteristics and the weights.Type: GrantFiled: April 25, 2022Date of Patent: May 13, 2025Assignees: Robert Bosch GmbH, The Research Foundation for The State University of New YorkInventors: Shan Lin, Hongkai Chen, Sirajum Munir
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Patent number: 12285426Abstract: A method of treating and attenuating L-DOPA-induced dyskinesia, comprising administering an effective dose of at least one pharmacological agent, e.g., vilazodone, having serotonin-specific reuptake inhibition (SSRI) and serotonin receptor 1A (5-HT1AR) partial agonism activity, in conjunction with L-DOPA. Other agents, such as an L-DOPA decarboxylase inhibitor, e.g., carbidopa, or other adjunct treatments may also be provided.Type: GrantFiled: April 26, 2021Date of Patent: April 29, 2025Assignees: The Research Foundation for The State University of New York, Rosalind Franklin University of Medicine and Science, Board of Trustees of Michigan State UniversityInventors: Christopher Roy Bishop, Anthony West, Fredric Manfredsson
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Patent number: 12285437Abstract: A pre-prodrug, comprising a drug, e.g., doxorubicin, which has off-target toxicity (e.g., cardiotoxicity) with respect to its antineoplastic activity, and an amine functionality of the drug incorporated into a disubstituted maleimide (DMI). The pre-prodrug may be linked to a targeting or de-targeting agent or a polar modulator, e.g., charged ligand, amino acid, peptide, etc., to increase therapeutic index. The pre-prodrug is hydrolyzed to the prodrug, having a disubstituted maleamic acid (DMA). A polar modulator such as glutamic acid prevents cellular uptake of the prodrug, but not the doxorubicin drug released from the prodrug after dissociation. The prodrug is pH sensitive, and below pH 7.0, tends to cleave to form free drug and cyclized maleic anhydride. Tumor environments tend to be more acidic, e.g., pH 6.8, than cardiac tissue, e.g., pH 7.4, and therefore the heart is spared while the drug is selectively released within a tumor.Type: GrantFiled: October 30, 2020Date of Patent: April 29, 2025Assignee: The Research Foundation for The State University of New YorkInventors: Ming An, Lan Yao, Anqi Zhang
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Patent number: 12289614Abstract: Methods, computer program products, and systems can include, for example: receiving a plurality of signal instances of a signal emitted by a transmitter, wherein respective signal instances of the plurality of signal instances are collected at different positions. There is also set forth herein receiving by a movable receiver moving within a first location a plurality of signal instances of a signal emitted by a transmitter, wherein signal instances defining the plurality of signal instances are collected by the moveable receiver at different respective receiver positions within the first location. There is also set forth herein discovering a direction of arrival parameter value that specifies a direction of arrival of the signal emitted by the transmitter, wherein the discovering includes using a set of signal instances from the plurality of signal instances.Type: GrantFiled: April 15, 2022Date of Patent: April 29, 2025Assignee: The Research Foundation for The State University of New YorkInventors: Dola Saha, Aveek Dutta, Maqsood Abdul Careem
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Patent number: 12276764Abstract: Provided are a device for detecting sub-atomic particles and method of fabrication thereof. The device includes a plurality of scintillators, a detector provided on a first end of the plurality of scintillators and a prismatoid provided on a second end of the plurality of scintillators. The prismatoid redirects light between adjacent scintillators of the plurality of scintillators.Type: GrantFiled: December 4, 2023Date of Patent: April 15, 2025Assignee: The Research Foundation for The State University of New YorkInventors: Amirhossein Goldan, Andrew Labella, Wei Zhao, Anthony Lubinsky
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Patent number: 12269071Abstract: Systems and methods for self-cleaning a surface of an object where an electrodynamic shield is mounted to a surface of the object. The electrodynamic shield includes one or more sets of electrodes atop a substrate, at least one or more sets of electrodes being covered in a protective film. A coating is applied to the top surface of the protection film. A signal pulse generator is connected to the one or more sets of electrodes. The signal pulse generator generates a pulse signal that causes the one or more sets of electrodes to generate an electric field. The pulse signal comprises a plurality of different pulse signals which have phase differences between consecutive signals, and the electric field causes a particle atop the coating to experience an electrostatic force and be repelled away from the coating. These pulse signals (including shapes, amplitudes, shifts, and frequencies) can be tuned to increase efficiency of removal depending on dust type and relative humidity.Type: GrantFiled: September 11, 2018Date of Patent: April 8, 2025Assignee: The Research Foundation for the State University of New YorkInventors: Alexander Orlov, Shrish Patel, James F. Smith
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Patent number: 12269803Abstract: The present disclosure is concerned with small molecule modulators of KLF15 signaling useful for treating various disorders such as, for example, kidney disease (e.g., chronic kidney disease), heart disease, obesity, or a neurodegenerative disorder (e.g., amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, traumatic brain injury, vascular dementia, Huntington's disease, mental retardation, and attention deficit and hyperactivity disorder (ADHD)). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: March 2, 2023Date of Patent: April 8, 2025Assignees: United States Government as Represented by the Department of Veterans Affairs, Icahn School of Medicine at Mount Sinai, The Research Foundation for the State University of New YorkInventors: Sandeep Mallipattu, Bhaskar Das
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Patent number: 12272059Abstract: A method of testing an impedance-sensitive system with a switching device, wherein the method comprises: switching the disconnecting device into the on-state configured to permit transmission of energy via the coil; implementing a first measurement with the impedance-sensitive system; switching the disconnecting device into the off-state configured to permit damping of the external positioning signal that couples into the coil so as to reduce the undesirable oscillations of the coil; implementing a second measurement with the impedance-sensitive system; performing a comparison of the first measurement and the second measurement; performing a verification of the comparison with a target specification; and displaying a correct function and/or a malfunction depending on the verification.Type: GrantFiled: July 26, 2023Date of Patent: April 8, 2025Assignee: The Research Foundation for The State University of New YorkInventors: Joel Haskin Saltz, Tahsin M. Kurc, Yi Gao, Wei Zhu, Si Wen, Tianhao Zhao, Sampurna Shrestha
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Patent number: 12264207Abstract: A rotary engine that generates electricity using differences in relative humidity. A water-responsive material expands and contracts as water evaporates which drives the rotation of two wheels. The rotary motion drives an electrical generator which produces electricity. In another embodiment, the water-responsive material is used to actuate an artificial muscle of a robotic device.Type: GrantFiled: March 26, 2021Date of Patent: April 1, 2025Assignee: Research Foundation of the City University of New YorkInventors: Xi Chen, Rein V. Ulijn, Zhi-Lun Liu, Yi-Ren Wang, Daniela Kroiss, Haozhen Wang