Abstract: An edge device for monitoring safety of a highway work zone is disclosed. The edge device includes at least one camera, one or more processors, and memory. The at least one camera is configured to capture images in sequence. The memory stores computer-executable instructions that, when executed, cause the one or more processors to: perform vehicle detection over an input of a data stream of the images, from the at least one camera, utilizing just-in-time processing; determine a level of safety by tracking vehicles detected and performing a time sequence analysis of the vehicles; and send a signal to one or more assisted reality devices indicating the level of safety thereto.

Abstract: Methods and compositions of storing a biological material are described herein. In some embodiments, these methods provide one or more advantages over current methods. For example, methods described herein can be used to prepare and process biological materials for storage at elevated temperatures. In one aspect, a method of storing a biological material comprises providing a preservation composition and exposing the preservation composition to electromagnetic radiation to form an amorphous solid matrix containing the biological material. In some embodiments, the method further comprises monitoring temperature of the preservation composition during the exposure to the electromagnetic radiation.

Abstract: In preferred embodiments, a short circuit protection system for a wide-band gap power electronics converter composed of multiple half-bridge legs is presented. The main approaches of the system are a single point of monitoring (SPM) for multiple switching legs, and non-invasive implementation and fast speed of the short circuit current detection. Ultra-high frequency (UHF) AC current, tens or hundreds of MHz, flowing through the DC-link capacitors represents the short circuit current occurred at the multiple switching legs. To capture the UHF AC current, a non-invasive MHz bandwidth magnetic current sensor is applied to the PCB conduction path of the converter. In this digest, simulation results of the short circuit current representation through the DC-link network and the magnetic field distribution in PCB layout for the selection of the proper location of the detection, and experimental results showing the UHF AC current sensing performance are presented.

Abstract: Provided are antibodies, and fragments and derivatives thereof, particularly humanized derivatives thereof, which bind to tumor antigens. Also provided are nucleic acid molecules encoding chimeric antigen receptors (CARs) that bind to tumor antigens, polypeptides and CARs encoded by the nucleic acid molecules, vectors and host cells that include the nucleic acid molecules, methods of making the same, and methods for using the same to generate a persisting population of genetically engineered T cells in a subject, expanding a population of genetically engineered T cells in a subject, modulating the amount of cytokine secreted by a T cell, reducing the amount of activation-induced calcium influx into a T cell, providing an anti-tumor immunity to a subject, treating a mammal having a MUC1-associated disease or disorder, stimulating a T cell-mediated immune response to a target cell population or tissue in a subject, and imaging a MUC1-associated tumor.

Abstract: Provided are antibodies, and fragments, derivatives, and nanoparticle conjugates thereof, particularly humanized derivatives thereof, which bind to tumor antigens. Also provided are nucleic acid molecules encoding chimeric antigen receptors (CARs) that bind to tumor antigens, polypeptides and CARs encoded by the nucleic acid molecules, vectors and host cells that include the nucleic acid molecules, methods of making the same, and methods for using the same to generate a persisting population of genetically engineered T cells in a subject, expanding a population of genetically engineered T cells in a subject, modulating the amount of cytokine secreted by a T cell, reducing the amount of activation-induced calcium influx into a T cell, providing an anti-tumor immunity to a subject, treating a mammal having a MUC1-associated disease or disorder, stimulating a T cell-mediated immune response to a target cell population or tissue in a subject, and imaging a MUC1-associated tumor.

Abstract: In one aspect, separation media are described herein operable for removing one or more water contaminants including NOM and derivatives thereof. Briefly, a separation medium includes a nanoparticle support and an oligomeric stationary phase forming a film on individual nanoparticles of the support, the film having thickness of 1 to 100 nm. In some embodiments, oligomeric chains of the stationary phase are covalently bonded to the individual nanoparticles.

Abstract: Systems and methods for efficient and automatic determination of radiation beam configurations for patient-specific radiation therapy planning are disclosed. According to an aspect, a method includes receiving data based on patient information and geometric characterization of one or more organs at risk proximate to a target volume of a patient. The method includes determining automatically one or more radiation treatment beam configuration sets. Further, the method includes presenting the determined one or more radiation beam configuration sets via a user interface.

Abstract: A radiation treatment planning system can include a machine learning system that receives patient data, including an image scan (e.g., CT scan) and contour(s), a physician prescription, including planning target and dose, and device (radiation beam) data and outputs predicted fluence maps. The machine learning system includes at least two stages, where a stage of the at least two stages includes converting image scans from the patient data to projection images. A treatment planning system can receive the predicted fluence maps and generates treatment plans without performing inverse optimization.

Abstract: Systems and methods for radiation treatment planning based on a model of planning strategies knowledge including treatment states and treatment actions are disclosed. According to an aspect, a method includes receiving geometric characterization data of a target volume for radiation treatment of a patient. The method also includes receiving geometric characterization data of at least one organ at risk proximate the target volume. Further, the method includes constructing a model for applying a predetermined radiation dosage to the target volume based on the received data. The model includes treatment states and associated treatment actions selectable to implement at each state. The method includes presenting information about at least one treatment state, the treatment actions associated with the at least one treatment state, and the rewards associated with the treatment actions associated with the at least one treatment state. The method also includes reconstructing the model.

Abstract: In one aspect, composite carbide compositions are described herein which can facilitate the efficient and/or economical manufacture of articles comprising SiC. Briefly, a composite carbide composition comprises silicon carbide (SiC) particles and a silica interparticle phase covalently bonded to the SiC particles.

Abstract: Silicon carbide (SiC) is an inert material with excellent biocompatibility properties. The biocompatibility is associated with the chemical inertness of the material. Tissue response to inert material is the formation of thin fibrous capsule. In some embodiments described herein, the conversion of SiC from inert material to bioactive material capable of stimulating cell function and making direct bond with tissue is described and the body response to bioactive materials is direct binding without any fibrous capsule.

Abstract: Various examples are provided related to diode clamped solid-state circuit breakers (SSCBs). Their configuration allows operation of the SSCB without dynamic voltage balancing issues. In one example, a diode clamped SSCB includes source-side switches and line-side switches connected between a DC source connection and a line-side connection. Clamping capacitors are connected at a common connection point between the source-side and line side switches and source-side and line-side clamping diodes are connected between the source-side switches and line-side switches and the clamping capacitors. Sequential switching of the source-side switches or line-side switches can avoid dynamic voltage balancing issues.

Abstract: Carbon dioxide and ash are two major waste by-products from coal fire production. Presented herein is are methods, material, and devices for storing carbon using high ash-content building material. The idea is to generate materials with commercial values to offset the cost for carbon capture. Ash with alkali activator (geopolymer) concrete has been studied extensively for its superior performance (higher strength) than ordinary Portland cement (OPC) concrete. However, most geopolymer concrete needs energy input in the forms of pressure and heat, which in turn are usually based on electricity produced through power plants.

Abstract: Devices, systems, and methods for heterogeneous catalytic quenching of hydrogen peroxide (H2O2) in a water source are disclosed. An exemplary device includes a column containing a catalytic material. The catalytic material can include self-supported granules of Fe(III) oxide. Catalytic reactor systems incorporating the columns and methods of making and using the same are also disclosed.

Abstract: Systems and methods for automatic, customized radiation treatment plan generation for cancer are disclosed. According to an aspect, a method includes receiving data indicating anatomy information of a patient and radiation beam characteristics of a radiation therapy system. Further, the method includes determining energy levels for application of radiation beams to the patient.

Abstract: In one aspect, systems and methods for the efficient and cost-effective removal of bromide from wastewater streams are described herein. Briefly, a system for bromide removal comprises pretreatment apparatus operable for at least partial removal of background ionic species from the wastewater stream and/or dilution of the background ionic species in the wastewater stream. The system also comprises bromide capture apparatus operable for removal of bromide from the pretreated wastewater stream, wherein the system removes bromide from the wastewater stream at an efficiency of at least 80 percent. In some embodiments, bromide is recovered from the capture apparatus and reused in flue gas treatment applications.

Abstract: Disclosed herein are unique single stranded DNA oligonucleotide products identified as binding with high affinity and specificity to ovarian tumor cells that may be used in the delivery of therapy to and diagnosis of ovarian cancer.

Abstract: Apparatuses including power electronics circuitry are provided. The power electronics circuitry includes at least one power converter that is coupled to a DC bus. Moreover, in some embodiments, the at least one power converter is configured to regulate a voltage of the DC bus. Related methods of operating an apparatus including power electronics circuitry are also provided.

Abstract: Materials comprising metamaterials exhibiting form-induced birefringence and anisotropic optical properties are provided. The disclosed articles comprise structures with critical dimensions which are on the order of or smaller than the wavelength for the gigahertz and terahertz spectral range. Methods of preparing same using stereolithography are disclosed. In a further aspect, the disclosed methods pertain to spectroscopic ellipsometry methods comprising a biaxial (orthorhombic) layer homogenization approach is to analyze the terahertz ellipsometric data obtained at three different sample azimuth orientations. The disclosed articles and methods demonstrate provide an avenue to fabricate metamaterials for the terahertz spectral range and allows tailoring of the polarizability and anisotropy of the host material. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Example photoconductive devices and example methods for using photoconductive devices are described. An example method may include providing a photoconductive device having a metal-semiconductor-metal structure. The method may also include controlling, based on a first input state, illumination of the photoconductive device by a first optical beam during a time period, and controlling, based on a second input state, illumination of the photoconductive device by a second optical beam during the time period. Further, the method may include detecting an amount of current produced by the photoconductive device during the time period, and based on the detected amount of current, providing an output indicative of the first input state and the second input state. The example devices can be used individually as discrete components or in integrated circuits for memory or logic applications.