Patents Assigned to University of Ottawa Heart Institute
  • Patent number: 8912355
    Abstract: Described herein are compositions of an linoleic phospholipid for inhibiting inflammatory pathways or neurodegenerative processes. Also provided are uses of such compositions and methods of inhibiting inflammatory or neurodegenerative processes by administering a composition that includes an linoleic phospholipid and optionally a carrier to a cell, cell culture or subject in need of such treatment.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: December 16, 2014
    Assignee: University of Ottawa Heart Institute
    Inventors: Nihar Pandey, Daniel Sparks
  • Patent number: 8008257
    Abstract: A fusion protein comprising an arterial natriuretic factor (ANF) amino acid sequence linked to an albumin amino acid sequence by one or more peptide bonds is provided. The ANF amino acid sequence may be linked to the N-terminal, the C-terminal, or both the N-terminal and the C-terminal of the albumin amino acid sequence. Also provided is a nucleic acid molecule encoding the fusion protein and a vector comprising the nucleic acid molecule. Methods for treating or preventing cardiovascular or renal disease comprising administration of an effective amount of the fusion protein, or nucleic acid encoding the fusion protein, are also disclosed.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: August 30, 2011
    Assignees: University of Ottawa Heart Institute, McMaster University
    Inventors: Adolfo J. De Bold, Mercedes L. Kuroski De Bold, William Sheffield
  • Publication number: 20070179925
    Abstract: An expert system for assigning and tracking physical activity programs for patients with coronary artery disease provides user interfaces for recruiters who screen and enroll the patients as program participants in the physical activity programs; for coaches who monitor program participants and guide them through the physical activity program; and for program participants who create their own physical activity schedules,and log their physical activities. Expert system algorithms assign predefined physical activity programs to the program participants at predefined program milestones based on predefined criteria.
    Type: Application
    Filed: January 31, 2006
    Publication date: August 2, 2007
    Applicant: University of Ottawa Heart Institute
    Inventors: Robert Reid, Louise Morrin, Sophia Papadakis, Louise Beaton