Abstract: The invention relates to a genetic probe, wherein the genetic probe comprises: an oligonucleotide, or an oligonucleotide analogue, with a Raman-active moiety incorporated therein, wherein the Raman-active moiety is incorporated into a base of the oligonucleotide or oligonucleotide thereof; and associated methods, uses, kits and compositions for determining a single point variant nucleotide in a target nucleic acid.

Abstract: This document provides methods and materials for reducing ischemia-reperfusion injury. For example, methods and materials for administering ABA to reduce tissue injury caused by reperfusion following ischemia are provided.

Abstract: This document provides methods and materials for reducing ischemia-reperfusion injury. For example, methods and materials for administering ABA to reduce tissue injury caused by reperfusion following ischemia are provided.

Abstract: The invention relates to a method for generating electromagnetic radiation (preferably UV, VUV, XUV, or X-rays), to an optical short-period undulator (10) and to a free-electron laser comprising the latter. To accomplish the method, a high-energy electrically charged particle beam (5) is provided, and high-intensity electromagnetic pulses (7, 7a, 7b) are generated, and by interfering said pulses with one another an electromagnetic standing wave is created, wherein said standing wave has an electric field strength of a pre-determined peak value. The particle beam is directed through the non-steady electromagnetic field of the standing wave in or in the vicinity of a plane spanned by nodes with maximal electric field strength of said electromagnetic standing wave.

Abstract: The present invention relates to a method and an arrangement to generate a coherent electromagnetic radiation containing at most a few optical cycles in the extreme ultraviolet/vacuum ultraviolet domain. The inventive method comprises the steps of providing an electron package (15) of relativistic velocity; modulating said electron package (15) with high intensity laser light (17) in an undulator (20) having an undulator period smaller than the undulator period (?u) satisfying the resonance condition, producing thereby an electron package formed of electron microbunches; and passing the electron package (15) of electron microbunches leaving said undulator (20) through a static magnetic field, and generating thereby a coherent electromagnetic radiation, wherein said static magnetic field is generated in conformity with the coherent electromagnetic radiation to be achieved.

Abstract: The invention relates to a such particle accelerator setup (1, 11) and method based on the total reflection of electromagnetic pulses with a frequency falling into the THz frequency domain that utilize the evanescent field for the acceleration of electrically charged particles. Said setup includes a radiation source (5) to emit high-energy THz-pulses, preferably comprising a few optical cycles, having a large peak electric field strength, as well as two optical elements (2, 12) in the form of a pair of bulk crystals made of a substance that exhibits large refractive index, low dispersion and high optical destruction threshold, wherein said optical elements are transparent for the THz radiation. The inventive solutions represent much simpler, more compact and more cost effective alternatives compared to the prior art particle accelerator setups.

Abstract: The present invention relates to a method and an arrangement to generate a coherent electromagnetic radiation containing at most a few optical cycles in the extreme ultraviolet/vacuum ultraviolet domain. The inventive method comprises the steps of providing an electron package (15) of relativistic velocity; modulating said electron package (15) with high intensity laser light (17) in an undulator (20) having an undulator period smaller than the undulator period (?u) satisfying the resonance condition, producing thereby an electron package formed of electron microbunches; and passing the electron package (15) of electron microbunches leaving said undulator (20) through a static magnetic field, and generating thereby a coherent electromagnetic radiation, wherein said static magnetic field is generated in conformity with the coherent electromagnetic radiation to be achieved.

Abstract: The invention relates to a such particle accelerator setup (1, 11) and method based on the total reflection of electromagnetic pulses with a frequency falling into the THz frequency domain that utilize the evanescent filed for the acceleration of electrically charged particles. Said setup includes a radiation source (5) to emit high-energy THz-pulses, preferably comprising a few optical cycles, having a large peak electric field strength, as well as two optical elements (2, 12) in the form of a pair of bulk crystals made of a substance that exhibits large refractive index, low dispersion and high optical destruction threshold, wherein said optical elements are transparent for the THz radiation. The inventive solutions represent much simpler, more compact and more cost effective alternatives compared to the prior art particle accelerator setups.

Abstract: The invention relates to a method for generating electromagnetic radiation (preferably UV, VUV, XUV, or X-rays), to an optical short-period undulator (10) and to a free-electron laser comprising the latter. To accomplish the method, a high-energy electrically charged particle beam (5) is provided, and high-intensity electromagnetic pulses (7, 7a, 7b) are generated, and by interfering said pulses with one another an electromagnetic standing wave is created, wherein said standing wave has an electric field strength of a pre-determined peak value. The particle beam is directed through the non-steady electromagnetic field of the standing wave in or in the vicinity of a plane spanned by nodes with maximal electric field strength of said electromagnetic standing wave.