Abstract: Compounds and methods for targeted immune system delivery are disclosed. Pharmaceutical compositions including the disclosed compounds and a pharmaceutically acceptable excipient are also disclosed. Methods of targeted delivery to an antigen-presenting cell, and methods of treating or preventing a disease or condition susceptible to treatment by immunomodulation are disclosed.
Type:
Grant
Filed:
October 4, 2013
Date of Patent:
May 8, 2018
Assignees:
Northeastern University, National Institute of Agricultural Technology, University of Padova
Inventors:
Juan Sebastian Pappalardo, Micaela Toniutti, Stefano Salmaso, Tatyana S. Levchenko, Vladimir Torchilin
Abstract: The invention provides a white sintered glass-ceramic tile and a method for preparing the white sintered glass-ceramic tile. The white sintered glass-ceramic tile is a single fired tile with a glazed glass-ceramic layer and a porous glass-ceramic layer, wherein each layer is prepared using same starting raw materials. The method includes milling the starting raw materials to obtain a homogenous mixture. The homogenous mixture is melted and poured in water to obtain glass frits. The glass frits are milled and thereafter, sieved to obtain glass frit powder with particle size of below 100 micron (?m). A mixture of the glass frit powder and one or more foaming agents is cold pressed to form a porous glass-ceramic layer. Thereafter, the glass frit powder is deposited on the porous glass-ceramic layer to obtain a glazed glass-ceramic layer. Finally, both the layers are fired together.
Type:
Application
Filed:
January 25, 2016
Publication date:
July 27, 2017
Applicants:
The King Abdulaziz City for Science and Technology, University of Padova
Inventors:
Mohammed A. Binhussain, Hamad Al-Talasi, Mauro Marangoni, Enrico Bernardo, Paolo Colombo, Majed Binmajed