Patents Assigned to University of Pittsburgh-Of the Commonwealth Syste
  • Publication number: 20180221545
    Abstract: The invention relates to biodegradable, magnesium alloys, compositions and composites, methods for their preparation and applications for their use as implantable medical devices in load-bearing conditions. The magnesium alloys are composed of alloying elements selected from yttrium, calcium, zirconium, zinc, and strontium, with the remainder being magnesium and impurities due to production, and are prepared by melting together the elements and casting the resulting melted mixture. In certain embodiments, the methods of preparation include solution treatment and hot extrusion.
    Type: Application
    Filed: August 22, 2016
    Publication date: August 9, 2018
    Applicant: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTE M OF HIGHER EDUCATION
    Inventors: PRASHANT N. KUMTA, ABHIJIT ROY, DA-TREN CHOU, DAEHO HONG, VIJAY S. GORANTLA
  • Publication number: 20170251145
    Abstract: A passively powered image capture device includes a remote execution unit structured to receive commands from a base station and an imaging device coupled to the remote execution unit. The imaging device is structured to be controlled by the remote execution unit based on the commands received by the remote execution unit. The passively powered image capture device also includes an antenna and energy harvesting circuitry coupled to the antenna, the remote execution unit and the imaging device. The energy harvesting circuitry is structured to convert RF energy received by the antenna to DC energy for powering the remote execution unit and the imaging device.
    Type: Application
    Filed: September 21, 2015
    Publication date: August 31, 2017
    Applicant: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTE M OF HIGHER EDUCATION
    Inventors: MARLIN H. MICKLE (DECEASED), ZIQUN ZHOU, KARA NICOLE-SIMMS BOCAN, VYASA SAI, AJAY OGIRALA, ERVIN SEJDIC, NICHOLAS G. FRANCONI
  • Publication number: 20170239398
    Abstract: The invention relates to a biodegradable, magnesium-containing bone screw for implanting into a patient body for use in medical applications, such as, orthopedic and craniofacial surgery. The bone screw has a tapered head, a threaded shaft and pointed tip. The composition of the bone screws provide for improved biodegradability and biocompatibility, and the features of the structure of the bone screws facilitates guidance and placement during implantation as well as reduces the potential for mechanical failures. Moreover, the bone screws are effective to provide targeted release of magnesium ions resulting in enhanced new bone formation.
    Type: Application
    Filed: August 27, 2015
    Publication date: August 24, 2017
    Applicant: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTE M OF HIGHER EDUCATION
    Inventors: CHARLES S. SFEIR, AMY CHAYA, ANDREW J. BROWN, SAYURI YOSHIZAWA
  • Publication number: 20170181657
    Abstract: A method of monitoring glucose transport and/or metabolism in a tissue or an organ of a subject using spin-locking magnetic resonance (MR) includes acquiring pre-glucose MR data by executing a pre-glucose chemical exchange spin-lock (CESL) pulse sequence a number of times each including applying pre-glucose chemical exchange spin-lock pulse sequence irradiation to the tissue or the organ, administering glucose to the subject, acquiring post-glucose MR data by executing a post-glucose chemical exchange spin-lock (CESL) pulse sequence a number of times each including applying post-glucose chemical exchange spin-lock (CESL) pulse sequence irradiation to the tissue or the organ, and using the pre-glucose MR data and the post-glucose MR data to generate a measure of glucose transport, glucose metabolism or both glucose transport and glucose metabolism in the tissue or the organ.
    Type: Application
    Filed: April 22, 2015
    Publication date: June 29, 2017
    Applicant: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTE M OF HIGHER EDUCATION
    Inventors: Tao Jin, Seong-Gi Kim, Hunter S. Mehrens, Kristy S. Hendrich
  • Publication number: 20130006322
    Abstract: Provided herein are methods and devices useful for inhibiting or treating urological conditions, such as overactive bladder (OAB) symptoms including bladder overactivity, urinary frequency, urinary urgency, urinary incontinence, interstitial cystitis (IC), urinary retention, and pelvic pain; gastrointestinal conditions, such as fecal incontinence, irritable bowel syndrome (IBS), and constipation; and sexual conditions, such as premature ejaculation, erectile disorder, and female sexual arousal disorder by non-invasive transcutaneous electrical stimulation of the foot.
    Type: Application
    Filed: September 30, 2010
    Publication date: January 3, 2013
    Applicant: UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTE
    Inventor: Changfeng Tai
  • Publication number: 20120156176
    Abstract: Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers.
    Type: Application
    Filed: April 30, 2010
    Publication date: June 21, 2012
    Applicant: University of Pittsburgh-Of the Commonwealth Syste
    Inventors: Kazuro Lee Fujimoto, Zuwei Ma, Jianjun Guan, William R. Wagner
  • Publication number: 20120122992
    Abstract: Compounds that stimulate fibroblast growth factor production, and thus cell growth are provided. Also provided are compositions comprising the compounds and methods of using the compounds. The compounds can be used to treat wounds, to expand cell populations, such as hematopoietic cells, or to grow tissue in vitro, among other uses.
    Type: Application
    Filed: March 19, 2010
    Publication date: May 17, 2012
    Applicant: University of Pittsburgh-Of the Commonwealth Syste
    Inventors: Billy W. Day, Waikok Michael Tsang, Vasiliy N. Korotchenko