Abstract: The present invention relates to novel synthetic muc-1 peptides and muc-1 analogs comprising at least two 20-amino acid tandem repeats of muc-1, wherein said synthetic muc-1 peptide is capable of attaining native conformation in the absence of glycosylation. The invention also relates methods of producing the peptides. The invention further relates to uses of the peptides, such as for vaccines and diagnostic testing.
Type:
Grant
Filed:
July 30, 1993
Date of Patent:
April 28, 1998
Assignee:
University Of Pittsburgh University Patent Committee Policy And Procedures
Inventors:
Olivera J. Finn, J. Darrell Fontenot, Ronald C. Montelaro