Patents Assigned to University of Queensland
-
Patent number: 8880207Abstract: An apparatus for diagnosing sleep disorders such as OASHS from snore sounds includes a segmentation module (126) coupled to a data logger (124) to provide segments of the digitized audio signal to a Snore Segment Identifier (128). A total airways response (TAR) module (130), pitch calculator (132), and MFCC calculator (134) are each coupled to an output side of the snore segment identifier module (128). Each of these modules is respectively arranged to calculate pitch, bispectrum, diagonal slice, and MFCC parameters for the snore segments received from the snore segment identifier (128). Similarly, the NGI calculator (136) produces a non-Gaussianity index for the digitized audio signal. A classification module (144) is arranged to process the calculated parameters and compare a resulting diagnosis probability to a predetermined threshold value.Type: GrantFiled: December 10, 2009Date of Patent: November 4, 2014Assignee: The University of QueenslandInventors: Udantha Abeyratne, Asela Samantha Karunajeewa, Houman Ghaemmaghami
-
Publication number: 20140315796Abstract: The present invention provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for therapies such as metabolic syndrome, obesity, type II diabetes, fibrosis and cardiovascular diseases, whether they are used alone or in combination with other treatment modalities.Type: ApplicationFiled: July 27, 2012Publication date: October 23, 2014Applicant: The University of QueenslandInventors: David Fairlie, Ligong Liu, Mei-Kwan Yau, Jacky Yung Suen, Robert Reid, Rink-Jan Lohman, Abishek Venkatasubramania Iyer, Junxian Lim, Lindsay Charles Brown
-
Patent number: 8858951Abstract: The invention is directed to the use of (i) a first antigen corresponding to a target antigen of interest, together with (ii) a second antigen, corresponding to a modified form of the target antigen, whose rate of intracellular proteolytic degradation is increased, enhanced or otherwise elevated relative to the first antigen, in compositions and methods for inducing both humoral and cellular immunity in an individual. The ability to provide compositions, which are capable of inducing both host-protective antibody and cell-mediated immune responses, facilitates the generation of immunogenic compositions capable of combating, inter alia, conditions that have long latency periods and, therefore, benefit from the dual approach of prophylaxis and therapy in one delivery.Type: GrantFiled: April 18, 2002Date of Patent: October 14, 2014Assignee: The University of QueenslandInventor: Ian Hector Frazer
-
Patent number: 8860414Abstract: A gradient coil arrangement for use in a magnetic imaging system, the imaging system being for generating a magnetic imaging field in an imaging region provided in a bore. The coil arrangement includes a first portion having a substantially cylindrical shape for positioning in the bore, a second portion extending outwardly from an end of the first portion, the second portion being for positioning outside the bore and at least one coil for generating a gradient magnetic field in the imaging region, the at least one coil having a first part provided on the first portion and a second part provided on the second portion.Type: GrantFiled: December 21, 2009Date of Patent: October 14, 2014Assignee: The University of QueenslandInventors: Ian Malcolm Brereton, Graham John Galloway, Viktor Vegh, Quang Minh Tieng
-
Patent number: 8840339Abstract: The invention provides a process for remediation of sites contaminated with metals such as former industrial sites and mines. In particular the invention provides a process for site remediation comprising the steps of: (a) adding metal-binding particles to a site containing one or more metal contaminants such that at least some of the one or metal contaminants are sequestered by the particles, and (b) populating the site with plants. The use of the particles of the present invention in association with plants, and microbiota associated with the plant roots can achieve sustainable phytostabilization of contaminated sites.Type: GrantFiled: June 23, 2009Date of Patent: September 23, 2014Assignee: The University of QueenslandInventors: Laurence Suzanne Rosa Rossato, Michael Monteiro, Michael Whittaker, Thomas Baumgartl, David Doley, Alex Pudmenzky, Susanne Schmidt
-
Patent number: 8822509Abstract: This invention discloses compositions and methods for inducing, promoting or otherwise facilitating pain relief. More particularly, the present invention discloses the use of sub-normovasodilatory doses of nitric oxide donors in the therapeutic management of vertebrate animals including humans, for the prevention or alleviation of pain, especially neuropathic pain. According to some embodiments of the present invention, nitric oxide donors are administered by any suitable route so as to provide concentrations of NO that are about ½ to 10?15 of those known to induce vasodilation in normal circulations.Type: GrantFiled: June 29, 2009Date of Patent: September 2, 2014Assignee: The University of QueenslandInventor: Maree Therese Smith
-
Patent number: 8790889Abstract: A method of activating a latent neural precursor cell population, comprising: (1) providing a neural cell population derived from the hippocampus; (2) introducing the neural cell population to a neurosphere-forming culture medium; and (3) activating the latent precursor cell population by treatment with a ?3 adrenergic receptor agonist.Type: GrantFiled: December 21, 2010Date of Patent: July 29, 2014Assignee: The University of QueenslandInventors: Dhanisha Jhaveri, Perry Francis Bartlett
-
Patent number: 8765677Abstract: This invention relates to an isolated, synthetic or recombinant peptide, wherein the peptide comprises the sequence: C K G K G A Xaa1 C R Xaa2 Xaa3 Xaa4 Y Xaa5 C C Xaa6 G Xaa7 C R Xaa8 Xaa9 R C SEQ ID NO: 1 wherein Xaa1, Xaa3, Xaa4, Xaa6, Xaa7 and Xaa8 are independently selected from serine and threonine; Xaa2 is selected from arginine and lysine; Xaa5 is selected from aspartic acid and glutamic acid; and Xaa9 is selected from glycine, alanine, valine, leucine and isoleucine.Type: GrantFiled: September 21, 2010Date of Patent: July 1, 2014Assignees: The University of Queensland, The University of SydneyInventors: Richard Lewis, David John Adams, Geza Berecki, Roger Drinkwater, Paul Francis Alewood, MacDonald James Christie
-
Patent number: 8754644Abstract: Apparatus for use in a magnetic resonance imaging system, the imaging system generating a magnetic imaging field in an imaging region (5), the apparatus including at least one coil for at least one of transmitting, receiving or transceiving an electromagnetic field, a field component (4) (such as a coil or a shield) and a drive (6) coupled to the field component for moving the field component (4) relative to the imaging region (5) to thereby modify the electromagnetic field during imaging process. The same concept can also be applied to nuclear imaging or nuclear spectroscopy apparatus.Type: GrantFiled: June 19, 2009Date of Patent: June 17, 2014Assignee: The University of QueenslandInventors: Adnan Trakic, Ewald Weber, Bing Keong Li, Stephen James Wilson, Wang Hua, Feng Liu, Stuart Crozier
-
Patent number: 8734697Abstract: A method for use in producing a patch having a number of projections thereon. The method includes providing a distribution member and filling material on a mold surface, the mold including a number of cavities extending from the mold surface for defining the patch projections, filling the cavities with filling material, at least in part by urging filling material from the distribution member into the cavities, causing the filling material to solidify and separating the solidified filling material and the mold to thereby form the patch.Type: GrantFiled: December 17, 2009Date of Patent: May 27, 2014Assignee: The University of QueenslandInventors: Xianfeng Chen, Mark Anthony Fernance Kendall, Tarl Prow, Anthony Paul Raphael
-
Patent number: 8728346Abstract: A method for preparing a suspension of LDH particles comprises the steps of preparing LDH precipitates by coprecipitation to form a mixture of LDH precipitates and solution; separating the LDH precipitates from the solution; washing the LDH precipitates to remove residual ions; mixing the LDH precipitates with water; and subjecting the mixture of LDH particles and water from step (d) to a hydrothermal treatment step by heating to a temperature of from greater than 80° C. to 150° C. for a period of about 1 hour to about 144 hours to form a well dispersed suspension of LDH particles in water.Type: GrantFiled: May 26, 2010Date of Patent: May 20, 2014Assignee: The University of QueenslandInventors: Gaoqing Lu, Zhiping Xu
-
Publication number: 20140127117Abstract: A method for preparing a suspension of LDH particles comprises the steps of preparing LDH precipitates by coprecipitation to form a mixture of LDH precipitates and solution; separating the LDH precipitates from the solution; washing the LDH precipitates to remove residual ions; mixing the LDH precipitates with water; and subjecting the mixture of LDH particles and water from step (d) to a hydrothermal treatment step by heating to a temperature of from greater than 80° C. to 150° C. for a period of about 1 hour to about 48 hours to form a well dispersed suspension of LDH particles in water.Type: ApplicationFiled: January 10, 2014Publication date: May 8, 2014Applicant: The University of QueenslandInventors: GAOQING LU, ZHIPING XU
-
Publication number: 20140053294Abstract: Primers suitable for nucleic acid sequence amplification of Pongamia plant genetic markers and a method of genetic analysis of Pongamia plants are provided. The primers comprise a repeat unit of two or three nucleotides repeated five to ten times together with a three prime extension of two or three nucleotides. Genetic markers amplified by the primers are also provided, from which may be produced further primers for genetic analysis of Pongamia plants. The primers, genetic markers and methods of genetic analysis may be suitable for selection and breeding of Pongamia plants having desired traits such as, or relating to, seed size, seed number, seed oil content, seed oil quality, seed flavour and toxicity, disease resistance, water use efficiency, nitrogen use efficiency, precocious flowering, flowering time, tree size, tree shape, growth rate, drought tolerance, salinity tolerance and/or growth in low-nutrient soils.Type: ApplicationFiled: November 18, 2011Publication date: February 20, 2014Applicant: The University of QueenslandInventor: Peter M. Gresshoff
-
Publication number: 20140038218Abstract: Disclosed are electrochemical methods, apparatus, systems and kits for the detection or monitoring of proteolysis of proteinaceous matrices such as fibrin clots. The methods, apparatus, systems and kits generally include the use of voltammetric techniques to measure the changes in current that result from diffusion of an electroactive species towards an electrode on proteolysis of a proteinaceous matrix.Type: ApplicationFiled: December 22, 2011Publication date: February 6, 2014Applicant: The University of QueenslandInventor: Krassen Dimitrov
-
Publication number: 20140038895Abstract: The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are antagonists of the RXFP3 receptor, and in some embodiments are selective antagonists of the RXFP3 receptor.Type: ApplicationFiled: September 8, 2011Publication date: February 6, 2014Applicants: The University of Queensland, Howard Florey Institute of Experimental Physiology and MedicineInventors: Karl Johan Rosengren, Linda Maria Haugaard-Kedstrom, Ross Alexander David Bathgate, Mohammed Akhter Hossain, John Desmond Wade, Andrew Lawrence Gundlach, Andrew J. Lawrence
-
Patent number: 8633261Abstract: The present invention relates to polymer composites prepared from a host polymer and particles. Specifically, this invention is concerned with the organic modification of the particles. More specifically, the particles are organically modified with at least two organic modifiers that are different and have specific chemical and physical properties.Type: GrantFiled: April 15, 2009Date of Patent: January 21, 2014Assignee: The University of QueenslandInventors: Darren Martin, Grant Edwards
-
Patent number: 8635027Abstract: A method of determining common three-dimensional structural features of protein surfaces is provided, as is use of representations of these common structures in molecular database searching and in designing focused molecular libraries. The method is particularly concerned with the analysis and representation of protein surfaces such as b-turns, loops and contact surfaces. In one form, the method identifies common locations and orientations of amino acid side-chains, simplified as C?-C? vectors. In another form, the method identifies common regions of surface charge represented by grid points in three-dimensional space. Further provided are common three dimensional structural features of proteins that can be used to search molecular databases for the purposes of identifying molecules that match these common three dimensional structural features.Type: GrantFiled: August 17, 2009Date of Patent: January 21, 2014Assignee: The University of QueenslandInventors: Mark Leslie Smythe, Tran Trung Tran, Darryn Bryant, Stephen Long, Peter Adams
-
Patent number: 8629241Abstract: Disclosed are short chain peptides that are constrained to adopt an alpha helicial conformation and their use as alpha helical scaffolds for directing amino acid side chains into positions analogous to those found in longer chain alpha helical peptides. Also disclosed is the use of these peptides for attaching peptidic or non-peptidic appendages in order to mimic side chains of longer alpha helical peptides. The peptides find use in mimicking naturally occurring peptides or proteins or in preparing new materials.Type: GrantFiled: May 30, 2012Date of Patent: January 14, 2014Assignee: The University of QueenslandInventors: David P. Fairlie, Nicholas E. Shepherd
-
Patent number: 8597383Abstract: A catalytic membrane reactor assembly for producing a hydrogen stream from a feed stream having liquid hydrocarbons, steam, and an oxygen source through the use of an autothermal reforming reaction, a water-gas-shift reaction, and a hydrogen permeable membrane.Type: GrantFiled: April 11, 2011Date of Patent: December 3, 2013Assignees: Saudi Arabian Oil Company, The University of QueenslandInventors: Thang V. Pham, Sai P. Katikaneni, Jorge N. Beltramini, Moses O. Adebajo, Joao Carlos Diniz Da Costa, Gao Qing Lu
-
Patent number: 8577452Abstract: A method for acquiring a physiological response from a test subject, particularly an auditory brainstem response, by presenting a plurality of stimuli, such as a Maximum Length Sequence, detecting electrophysiological signals in response to the stimuli, generating a recover signal based on the stimuli and determining the physiological response from the electrophysiological signals and the recovery signal.Type: GrantFiled: July 12, 2007Date of Patent: November 5, 2013Assignee: The University of QueenslandInventors: Andrew P Bradley, Wayne J Wilson